最近审阅: 30 十月 2020
最近更新: 20 十二月 2018

小结

定义

病史和体格检查

关键诊断因素

  • 存在的危险因素
  • 疲劳
  • 厌食
  • 体重减轻
  • 色素过度沉着
  • 嗜盐症

其他诊断因素

  • 恶心
  • 呕吐
  • 低血压
  • 关节痛和肌痛

危险因素

  • 女性
  • 肾上腺皮质自身抗体
  • 肾上腺出血
  • 自身免疫性疾病
  • 结核病 (TB)
  • 非结核菌感染
  • 真菌感染
  • HIV
  • 抑制皮质醇分泌的药物
  • 转移性恶性肿瘤
  • 乳糜泻
  • 结节病

诊断性检查

首要检查

  • 血清电解质
  • 血尿素
  • 全血细胞计数(FBC)
  • 清晨血清皮质醇
更多 首要检查

需考虑的检查

  • 促肾上腺皮质激素 (ACTH) 刺激试验
  • 血清 ACTH
  • 血浆肾素活性
  • 血浆醛固酮
  • 血浆脱氢表雄酮 (DHEA)
  • 血浆硫酸脱氢表雄酮 (DHEAS)
  • 肾上腺抗体
  • 肾上腺 CT 或 MRI 检查
  • 胰岛素低血糖试验
  • 隔夜单次剂量美替拉酮试验
更多 需考虑的检查

治疗流程

撰稿人

Professor Emeritus and Honorary Consultant

Department of Endocrinology and Diabetes Mellitus

St. Vincent’s University Hospital

Dublin

Ireland

利益声明

TJMcK declares that he has no competing interests.

Dr T. Joseph McKenna would like to gratefully acknowledge Dr Shehzad Basaria and Dr Milena Braga-Basaria, previous contributors to this topic.

利益声明

SB and MBB declare that they have no competing interests.

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Division of Endocrinology

Case Medical Center

Cleveland

OH

利益声明

BA declares that he has no competing interests.

Instructor in Medicine

Brigham and Women's Hospital

Division of Endocrinology

Diabetes and Hypertension

Boston

MA

利益声明

RKG declares that he has no competing interests.

Head

Department of Endocrinology

Centre Hospitalier Universitaire de Bordeaux

Pessac

France

利益声明

AT declares that he has no competing interests.

Department of Endocrinology

Centre Hospitalier Universitaire de Bordeaux

Pessac

France

利益声明

BGC declares that she has no competing interests.

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