局灶性癫痫发作

  • 概述
  • 理论
  • 诊断
  • 治疗
  • 随访
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参考文献

关键文献

Fisher RS, Cross JH, French JA, et al. Operational classification of seizure types by the International League Against Epilepsy: position paper of the ILAE Commission for Classification and Terminology. Epilepsia. 2017 Apr;58(4):522-30.全文  摘要

Scheffer IE, Berkovic S, Capovilla G, et al. ILAE classification of the epilepsies: position paper of the ILAE Commission for Classification and Terminology. Epilepsia. 2017 Apr;58(4):512-21.全文  摘要

Leone MA, Giussani G, Nevitt SJ, et al. Immediate antiepileptic drug treatment, versus placebo, deferred, or no treatment for first unprovoked seizure. Cochrane Database Syst Rev. 2021 May 4;(5):CD007144.全文  摘要

Kanner AM, Ashman E, Gloss D, et al. Practice guideline update summary: efficacy and tolerability of the new antiepileptic drugs I: treatment of new-onset epilepsy. Report of the American Epilepsy Society and the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology. Epilepsy Curr. 2018 Jul-Aug;18(4):260-8.全文  摘要

Kanner AM, Ashman E, Gloss D, et al. Practice guideline update summary: efficacy and tolerability of the new antiepileptic drugs II: treatment-resistant epilepsy. Report of the American Epilepsy Society and the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology. Epilepsy Curr. 2018 Jul-Aug;18(4):269-78.全文  摘要

Royal College of Obstetricians and Gynaecologists. Epilepsy in pregnancy (Green-top Guideline No.68). Jun 2016 (updated May 2018) [internet publication].全文

Nevitt SJ, Sudell M, Weston J, et al. Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data. Cochrane Database Syst Rev. 2017 Dec 15;(12):CD011412.全文  摘要

Boon P, De Cock E, Mertens A, et al. Neurostimulation for drug-resistant epilepsy: a systematic review of clinical evidence for efficacy, safety, contraindications and predictors for response. Curr Opin Neurol. 2018 Apr;31(2):198-210. 摘要

参考文献

1. Fisher RS, Cross JH, French JA, et al. Operational classification of seizure types by the International League Against Epilepsy: position paper of the ILAE Commission for Classification and Terminology. Epilepsia. 2017 Apr;58(4):522-30.全文  摘要

2. Fisher RS, Acevedo C, Arzimanoglou A, et al. ILAE official report: a practical clinical definition of epilepsy. Epilepsia. 2014 Apr;55(4):475-82.全文  摘要

3. Scheffer IE, Berkovic S, Capovilla G, et al. ILAE classification of the epilepsies: position paper of the ILAE Commission for Classification and Terminology. Epilepsia. 2017 Apr;58(4):512-21.全文  摘要

4. GBD 2016 Epilepsy Collaborators. Global, regional, and national burden of epilepsy, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol. 2019 Apr;18(4):357-75.全文  摘要

5. Fiest KM, Sauro KM, Wiebe S, et al. Prevalence and incidence of epilepsy: a systematic review and meta-analysis of international studies. Neurology. 2017 Jan 17;88(3):296-303.全文  摘要

6. Sen A, Jette N, Husain M, et al. Epilepsy in older people. Lancet. 2020 Feb 29;395(10225):735-48. 摘要

7. Rao VR, Parko KL. Clinical approach to posttraumatic epilepsy. Semin Neurol. 2015 Feb;35(1):57-63.全文  摘要

8. Salazar AM, Jabbari B, Vance SC, et al. Epilepsy after penetrating head injury. I. Clinical correlates: a report of the Vietnam Head Injury Study. Neurology. 1985 Oct;35(10):1406-14. 摘要

9. Annegers JF, Grabow JD, Groover RV, et al. Seizures after head trauma: a population study. Neurology. 1980 Jul;30(7 Pt 1):683-9. 摘要

10. Annegers JF, Hauser WA, Coan SP, et al. A population-based study of seizures after traumatic brain injuries. N Engl J Med. 1998 Jan 1;338(1):20-4.全文  摘要

11. Reddy DS, Volkmer R 2nd. Neurocysticercosis as an infectious acquired epilepsy worldwide. Seizure. 2017 Nov;52:176-81.全文  摘要

12. Englot DJ, Chang EF, Vecht CJ. Epilepsy and brain tumors. Handb Clin Neurol. 2016;134:267-85.全文  摘要

13. Maschio M. Brain tumor-related epilepsy. Curr Neuropharmacol. 2012 Jun;10(2):124-33.全文  摘要

14. Foy PM, Copeland GP, Shaw MD. The natural history of postoperative seizures. Acta Neurochir (Wien). 1981;57(1-2):15-22. 摘要

15. Severino M, Geraldo AF, Utz N, et al. Definitions and classification of malformations of cortical development: practical guidelines. Brain. 2020 Oct 1;143(10):2874-94.全文  摘要

16. Leventer RJ, Guerrini R, Dobyns WB. Malformations of cortical development and epilepsy. Dialogues Clin Neurosci. 2008;10(1):47-62.全文  摘要

17. Josephson CB, Rosenow F, Al-Shahi Salman R. Intracranial vascular malformations and epilepsy. Semin Neurol. 2015 Jun;35(3):223-34.全文  摘要

18. Hauser WA, Annegers JF, Kurland LT. Incidence of epilepsy and unprovoked seizures in Rochester, Minnesota: 1935-1984. Epilepsia. 1993 May-Jun;34(3):453-68. 摘要

19. Holtkamp M, Beghi E, Benninger F, et al. European Stroke Organisation guidelines for the management of post-stroke seizures and epilepsy. Eur Stroke J. 2017 Jun;2(2):103-15.全文  摘要

20. Subota A, Pham T, Jetté N, et al. The association between dementia and epilepsy: a systematic review and meta-analysis. Epilepsia. 2017 Jun;58(6):962-72.全文  摘要

21. Goulden KJ, Shinnar S, Koller H, et al. Epilepsy in children with mental retardation: a cohort study. Epilepsia. 1991 Sep-Oct;32(5):690-7. 摘要

22. Boillot M, Baulac S. Genetic models of focal epilepsies. J Neurosci Methods. 2016 Feb 15;260:132-43. 摘要

23. Ellis CA, Petrovski S, Berkovic SF. Epilepsy genetics: clinical impacts and biological insights. Lancet Neurol. 2020 Jan;19(1):93-100. 摘要

24. Tan HJ, Singh J, Gupta R, et al. Comparison of antiepileptic drugs, no treatment, or placebo for children with benign epilepsy with centro temporal spikes. Cochrane Database Syst Rev. 2014 Sep 5;(9):CD006779.全文  摘要

25. Bertram E. The relevance of kindling for human epilepsy. Epilepsia. 2007;48 Suppl 2:65-74. 摘要

26. Engelborghs S, D'Hooge R, De Deyn PP. Pathophysiology of epilepsy. Acta Neurol Belg. 2000 Dec;100(4):201-13. 摘要

27. Nemani VM. Binder DK. Emerging role of gap junctions in epilepsy. Histol Histopathol. 2005 Jan;20(1):253-9. 摘要

28. Meldrum BS, Rogawski MA. Molecular targets for antiepileptic drug development. Neurotherapeutics. 2007 Jan;4(1):18-61.全文  摘要

29. Nelson KB, Ellenberg JH. Predictors of epilepsy in children who have experienced febrile seizures. N Engl J Med. 1976 Nov 4;295(19):1029-33. 摘要

30. Dreier JW, Li J, Sun Y, et al. Evaluation of long-term risk of epilepsy, psychiatric disorders, and mortality among children with recurrent febrile seizures: a national cohort study in Denmark. JAMA Pediatr. 2019 Oct 7;173(12):1164-70. 摘要

31. Annegers JF, Hauser WA, Shirts SB, et al. Factors prognostic of unprovoked seizures after febrile convulsions. N Engl J Med. 1987 Feb 26;316(9):493-8. 摘要

32. Cendes F. Febrile seizures and mesial temporal sclerosis. Curr Opin Neurol. 2004 Apr;17(2):161-4. 摘要

33. Annegers JF, Hauser WA, Beghai E, et al. The risk of unprovoked seizures after encephalitis and meningitis. Neurology. 1988 Sep;38(9):1407-10. 摘要

34. White AC Jr, Coyle CM, Rajshekhar V, et al. Diagnosis and treatment of neurocysticercosis: 2017 clinical practice guidelines by the Infectious Diseases Society of America (IDSA) and the American Society of Tropical Medicine and Hygiene (ASTMH). Clin Infect Dis. 2018 Apr 3;66(8):e49-75.全文  摘要

35. Shinton RA, Gill JS, Zezulka AV, et al. The frequency of epilepsy preceding stroke. Case-control study in 230 patients. Lancet. 1987 Jan 3;1(8523):11-3. 摘要

36. College of Emergency Medicine (UK). Evidence-based flowchart for the management of first seizure in the emergency department. Dec 2009 [internet publication].全文

37. Koutroumanidis M, Arzimanoglou A, Caraballo R, et al. The role of EEG in the diagnosis and classification of the epilepsy syndromes: a tool for clinical practice by the ILAE Neurophysiology Task Force (Part 1). Epileptic Disord. 2017 Sep 1;19(3):233-98. 摘要

38. Salinsky M, Kanter R, Dasheiff RM. Effectiveness of multiple EEGs in supporting the diagnosis of epilepsy: an operational curve. Epilepsia. 1987 Jul-Aug;28(4):331-4. 摘要

39. Boon P, De Reuck J, Drieghe C, et al. Long-term video-EEG monitoring revisited. The value of interictal and ictal video-EEG recording, a follow-up study. Eur Neurol. 1994;34 Suppl 1:33-9. 摘要

40. Harden CL, Huff JS, Schwartz TH, et al. Reassessment: neuroimaging in the emergency patient presenting with seizure (an evidence-based review). Neurology. 2007 Oct 30;69(18):1772-80.全文  摘要

41. Gaillard WD, Chiron C, Cross JH, et al; ILAE, Subcommittee for Pediatric Neuroimaging. Guidelines for imaging infants and children with recent-onset epilepsy. Epilepsia. 2009 Sep;50(9):2147-53.全文  摘要

42. American College of Radiology. ACR appropriateness criteria: seizures and epilepsy. 2019 [internet publication].全文

43. Kuzniecky R, Burgard S, Faught E, et al. Predictive value of magnetic resonance imaging in temporal lobe epilepsy surgery. Arch Neurol. 1993 Jan;50(1):65-9. 摘要

44. Szaflarski JP, Gloss D, Binder JR, et al. Practice guideline summary: use of fMRI in the presurgical evaluation of patients with epilepsy. Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology. Neurology. 2017 Jan 24;88(4):395-402.全文  摘要

45. Bauer PR, Reitsma JB, Houweling BM, et al. Can fMRI safely replace the Wada test for preoperative assessment of language lateralisation? A meta-analysis and systematic review. J Neurol Neurosurg Psychiatry. 2014 May;85(5):581-8. 摘要

46. Massot-Tarrús A, Mousavi SR, Mirsattari SM. Comparing the intracarotid amobarbital test and functional MRI for the presurgical evaluation of language in epilepsy. Curr Neurol Neurosci Rep. 2017 Jul;17(7):54. 摘要

47. Massot-Tarrús A, White KP, Mousavi SR, et al. Concordance between fMRI and Wada test for memory lateralization in temporal lobe epilepsy: a meta-analysis and systematic review. Epilepsy Behav. 2020 Jun;107:107065. 摘要

48. Massot-Tarrús A, White K, Mirsattari SM. Comparing the Wada test and functional MRI for the presurgical evaluation of memory in temporal lobe epilepsy. Curr Neurol Neurosci Rep. 2019 May 1;19(6):31. 摘要

49. Salamon N, Kung J, Shaw SJ, et al. FDG-PET/MRI coregistration improves detection of cortical dysplasia in patients with epilepsy. Neurology. 2008 Nov 11;71(20):1594-601. 摘要

50. Opheim G, van der Kolk A, Markenroth Bloch K, et al. 7T Epilepsy Task Force consensus recommendations on the use of 7T MRI in clinical practice. Neurology. 2021 Feb 16;96(7):327-41. 摘要

51. Jankovic J, Lang AE. Movement disorders: diagnosis and assessment. In: Bradley WG, Daroff RB, Fenichel GM, et al, eds. Neurology in clinical practice. Principles of diagnosis and management. 4th ed. Philadelphia, PA: Elsevier; 2004:313-5.

52. Fahn S, Jankovic J. Principles and practice of movement disorders. Philadelphia, PA: Elsevier; 2007:409-33.

53. Bartsch T, Butler C. Transient amnesic syndromes. Nat Rev Neurol. 2013 Feb;9(2):86-97. 摘要

54. Kim J, Kwon Y, Yang Y, et al. Clinical experience of modified diffusion-weighted imaging protocol for lesion detection in transient global amnesia: an 8-year large-scale clinical study. J Neuroimaging. 2014 Jul-Aug;24(4):331-7. 摘要

55. Scheel M, Malkowsky C, Klingebiel R, et al. Magnetic resonance imaging in transient global amnesia: lessons learned from 198 cases. Clin Neuroradiol. 2012 Dec;22(4):335-40. 摘要

56. Avbersek A, Sisodiya S. Does the primary literature provide support for clinical signs used to distinguish psychogenic nonepileptic seizures from epileptic seizures? J Neurol Neurosurg Psychiatry. 2010 Jul;81(7):719-25. 摘要

57. Stone J, Burton C, Carson A. Recognising and explaining functional neurological disorder. BMJ. 2020 Oct 21;371:m3745. 摘要

58. Brown RJ, Reuber M. Psychological and psychiatric aspects of psychogenic non-epileptic seizures (PNES): A systematic review. Clin Psychol Rev. 2016 Apr;45:157-82.全文  摘要

59. Gidal B, Klein P, Hirsch LJ. Seizure clusters, rescue treatments, seizure action plans: unmet needs and emerging formulations. Epilepsy Behav. 2020 Nov;112:107391.全文  摘要

60. Mesraoua B, Abou-Khalil B, Hosni Khodair R, et al. Seizure clusters. J Drug Assess. 2021 Aug 14;10(1):86-90.全文  摘要

61. Jafarpour S, Hirsch LJ, Gaínza-Lein M, et al. Seizure cluster: definition, prevalence, consequences, and management. Seizure. 2019 May;68:9-15.全文  摘要

62. Leone MA, Giussani G, Nevitt SJ, et al. Immediate antiepileptic drug treatment, versus placebo, deferred, or no treatment for first unprovoked seizure. Cochrane Database Syst Rev. 2021 May 4;(5):CD007144.全文  摘要

63. Krumholz A, Wiebe S, Gronseth GS, et al. Evidence-based guideline: management of an unprovoked first seizure in adults. Report of the Guideline Development Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology. 2015 Apr 21;84(16):1705-13.全文  摘要

64. National Institute for Health and Care Excellence. Epilepsies in children, young people and adults. Apr 2022 [internet publication].全文

65. Thieffry S, Klein P, Baulac M, et al. Understanding the challenge of comparative effectiveness research in focal epilepsy: a review of network meta-analyses and real-world evidence on antiepileptic drugs. Epilepsia. 2020 Apr;61(4):595-609.全文  摘要

66. Perucca E, Brodie MJ, Kwan P, et al. 30 years of second-generation antiseizure medications: impact and future perspectives. Lancet Neurol. 2020 Jun;19(6):544-56. 摘要

67. Palleria C, Cozza G, Khengar R, et al. Safety profile of the newest antiepileptic drugs: a curated literature review. Curr Pharm Des. 2017;23(37):5606-24. 摘要

68. Tassone DM, Boyce E, Guyer J, et al. Pregabalin: a novel gamma-aminobutyric acid analogue in the treatment of neuropathic pain, partial-onset seizures, and anxiety disorders. Clin Ther. 2007 Jan;29(1):26-48. 摘要

69. Delahoy P, Thompson S, Marschner IC. Pregabalin versus gabapentin in partial epilepsy: a meta-analysis of dose-response relationships. BMC Neurol. 2010 Nov 1;10:104.全文  摘要

70. Panebianco M, Bresnahan R, Marson AG. Pregabalin add-on for drug-resistant focal epilepsy. Cochrane Database Syst Rev. 2022 Mar 29;3:CD005612.全文  摘要

71. Kim LG, Johnson TL, Marson AG, et al; MRC MESS Study Group. Prediction of risk of seizure recurrence after a single seizure and early epilepsy: further results from the MESS trial. Lancet Neurol. 2006 Apr;5(4):317-22.全文  摘要

72. Koch MW, Polman SK. Oxcarbazepine versus carbamazepine monotherapy for partial onset seizures. Cochrane Database Syst Rev. 2009 Oct 7;(4):CD006453.全文  摘要

73. Brodie MJ, Perucca E, Ryvlin P, et al; Levetiracetam Monotherapy Study Group. Comparison of levetiracetam and controlled-release carbamazepine in newly diagnosed epilepsy. Neurology. 2007 Feb 6;68(6):402-8. 摘要

74. Kanner AM, Ashman E, Gloss D, et al. Practice guideline update summary: efficacy and tolerability of the new antiepileptic drugs I: treatment of new-onset epilepsy. Report of the American Epilepsy Society and the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology. Epilepsy Curr. 2018 Jul-Aug;18(4):260-8.全文  摘要

75. Lattanzi S, Zaccara G, Giovannelli F, et al. Antiepileptic monotherapy in newly diagnosed focal epilepsy. A network meta-analysis. Acta Neurol Scand. 2019 Jan;139(1):33-41. 摘要

76. Nevitt SJ, Tudur Smith C, Weston J, et al. Lamotrigine versus carbamazepine monotherapy for epilepsy: an individual participant data review. Cochrane Database Syst Rev. 2018 Jun 28;(6):CD001031.全文  摘要

77. Nevitt SJ, Tudur Smith C, Marson AG. Oxcarbazepine versus phenytoin monotherapy for epilepsy: an individual participant data review. Cochrane Database Syst Rev. 2018 Oct 23;(10):CD003615.全文  摘要

78. Marson A, Burnside G, Appleton R, et al; SANAD II Collaborators. The SANAD II study of the effectiveness and cost-effectiveness of levetiracetam, zonisamide, or lamotrigine for newly diagnosed focal epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial. Lancet. 2021 Apr 10;397(10282):1363-74.全文  摘要

79. Reimers A, Ljung H. An evaluation of zonisamide, including its long-term efficacy, for the treatment of focal epilepsy. Expert Opin Pharmacother. 2019 Jun;20(8):909-15.全文  摘要

80. Nevitt SJ, Sudell M, Tudur Smith C, et al. Topiramate versus carbamazepine monotherapy for epilepsy: an individual participant data review. Cochrane Database Syst Rev. 2019 Jun 24;(6):CD012065.全文  摘要

81. Arnold S, Badalamenti V, Diaz A, et al. Conversion to brivaracetam monotherapy for the treatment of patients with focal seizures: two double-blind, randomized, multicenter, historical control, phase III studies. Epilepsy Res. 2018 Mar;141:73-82. 摘要

82. Milovanović JR, Janković SM, Pejčić A, et al. Evaluation of brivaracetam: a new drug to treat epilepsy. Expert Opin Pharmacother. 2017 Sep;18(13):1381-9. 摘要

83. Menzler K, Mross PM, Rosenow F, et al. First clinical postmarketing experiences in the treatment of epilepsies with brivaracetam: a retrospective observational multicentre study. BMJ Open. 2019 Nov 4;9(11):e030746.全文  摘要

84. Feyissa AM. Brivaracetam in the treatment of epilepsy: a review of clinical trial data. Neuropsychiatr Dis Treat. 2019 Sep 9;15:2587-600.全文  摘要

85. Simoens S. Lacosamide as adjunctive therapy for partial-onset epileptic seizures: a review of the clinical and economic literature. Curr Med Res Opin. 2011 Jul;27(7):1329-38. 摘要

86. Gidal BE, Laurenza A, Hussein Z, et al. Perampanel efficacy and tolerability with enzyme-inducing AEDs in patients with epilepsy. Neurology. 2015 May 12;84(19):1972-80.全文  摘要

87. Li-Na Z, Deng C, Hai-Jiao W, et al. Indirect comparison of third-generation antiepileptic drugs as adjunctive treatment for uncontrolled focal epilepsy. Epilepsy Res. 2018 Jan;139:60-72. 摘要

88. Brigo F, Lattanzi S, Igwe SC, et al. Zonisamide add-on therapy for focal epilepsy. Cochrane Database Syst Rev. 2020 Jul 24;(7):CD001416.全文  摘要

89. Bresnahan R, Panebianco M, Marson AG. Brivaracetam add-on therapy for drug-resistant epilepsy. Cochrane Database Syst Rev. 2022 Mar 14;3:CD011501.全文  摘要

90. Bresnahan R, Hounsome J, Jette N, et al. Topiramate add-on therapy for drug-resistant focal epilepsy. Cochrane Database Syst Rev. 2019 Oct 23;(10):CD001417.全文  摘要

91. Panebianco M, Bresnahan R, Ramaratnam S, et al. Lamotrigine add-on therapy for drug-resistant focal epilepsy. Cochrane Database Syst Rev. 2020 Mar 20;(3):CD001909.全文  摘要

92. Bresnahan R, Martin-McGill KJ, Williamson J, et al. Clobazam add-on therapy for drug-resistant epilepsy. Cochrane Database Syst Rev. 2019 Oct 22;(10):CD004154.全文  摘要

93. Potschka H, Trinka E. Perampanel: does it have broad-spectrum potential? Epilepsia. 2019 Mar;60 (suppl 1):22-36.全文  摘要

94. Panebianco M, Al-Bachari S, Hutton JL, et al. Gabapentin add-on treatment for drug-resistant focal epilepsy. Cochrane Database Syst Rev. 2021 Jan 12;(1):CD001415.全文  摘要

95. Bresnahan R, Atim-Oluk M, Marson AG. Oxcarbazepine add-on for drug-resistant focal epilepsy. Cochrane Database Syst Rev. 2020 Mar 4;(3):CD012433.全文  摘要

96. Mbizvo GK, Chandrasekar B, Nevitt SJ, et al. Levetiracetam add-on for drug-resistant focal epilepsy. Cochrane Database Syst Rev. 2020 Jun 30;(6):CD001901.全文

97. Babar RK, Bresnahan R, Gillespie CS, et al. Lacosamide add-on therapy for focal epilepsy. Cochrane Database Syst Rev. 2021 May 17;(5):CD008841.全文  摘要

98. Chang XC, Yuan H, Wang Y, et al. Eslicarbazepine acetate add-on therapy for drug-resistant focal epilepsy. Cochrane Database Syst Rev. 2021 Jun 22;(6):CD008907.全文  摘要

99. Krauss GL, Klein P, Brandt C, et al. Safety and efficacy of adjunctive cenobamate (YKP3089) in patients with uncontrolled focal seizures: a multicentre, double-blind, randomised, placebo-controlled, dose-response trial. Lancet Neurol. 2020 Jan;19(1):38-48. 摘要

100. Sperling MR, Abou-Khalil B, Aboumatar S, et al. Efficacy of cenobamate for uncontrolled focal seizures: post hoc analysis of a phase 3, multicenter, open-label study. Epilepsia. 2021 Dec;62(12):3005-15.全文  摘要

101. Kanner AM, Ashman E, Gloss D, et al. Practice guideline update summary: efficacy and tolerability of the new antiepileptic drugs II: treatment-resistant epilepsy. Report of the American Epilepsy Society and the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology. Epilepsy Curr. 2018 Jul-Aug;18(4):269-78.全文  摘要

102. National Institute for Health and Care Excellence. Cenobamate for treating focal onset seizures in epilepsy. Dec 2021 [internet publication].全文

103. Bresnahan R, Gianatsi M, Maguire MJ, et al. Vigabatrin add-on therapy for drug-resistant focal epilepsy. Cochrane Database Syst Rev. 2020 Jul 30;(7):CD007302.全文  摘要

104. Panebianco M, Prabhakar H, Marson AG. Rufinamide add-on therapy for drug-resistant epilepsy. Cochrane Database Syst Rev. 2020 Nov 8;(11):CD011772.全文  摘要

105. Bresnahan R, Martin-McGill KJ, Hutton JL, et al. Tiagabine add-on therapy for drug-resistant focal epilepsy. Cochrane Database Syst Rev. 2019 Oct 14;(10):CD001908.全文  摘要

106. Shi LL, Bresnahan R, Martin-McGill KJ, et al. Felbamate add-on therapy for drug-resistant focal epilepsy. Cochrane Database Syst Rev. 2019 Aug 1;(8):CD008295.全文  摘要

107. Slater J, Chung S, Huynh L, et al. Efficacy of antiepileptic drugs in the adjunctive treatment of refractory partial-onset seizures: meta-analysis of pivotal trials. Epilepsy Res. 2018 Jul;143:120-9.全文  摘要

108. Glauser T, Ben-Menachem E, Bourgeois B, et al; ILAE Subcommission on AED Guidelines. Updated ILAE evidence review of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes. Epilepsia. 2013 Mar;54(3):551-63.全文  摘要

109. Lattanzi S, Trinka E, Del Giovane C, et al. Antiepileptic drug monotherapy for epilepsy in the elderly: a systematic review and network meta-analysis. Epilepsia. 2019 Nov;60(11):2245-54. 摘要

110. Lezaic N, Gore G, Josephson CB, et al. The medical treatment of epilepsy in the elderly: a systematic review and meta-analysis. Epilepsia. 2019 Jul;60(7):1325-40. 摘要

111. Stephen LJ, Harden C, Tomson T, et al. Management of epilepsy in women. Lancet Neurol. 2019 May;18(5):481-91. 摘要

112. Johansen-Bibby A. Prescribing for pregnancy: epilepsy. Drug Ther Bull. 2020 Jul;58(7):103-6. 摘要

113. Wyszynski DF, Nambisan M, Surve T, et al; Antiepileptic Drug Pregnancy Registry. Increased rate of major malformations in offspring exposed to valproate during pregnancy. Neurology. 2005 Mar 22;64(6):961-5. 摘要

114. Holmes LB, Wyszynski DF, Lieberman E. The AED (antiepileptic drug) pregnancy registry: a 6-year experience. Arch Neurol. 2004 May;61(5):673-8.全文  摘要

115. Meador KJ, Baker GA, Browning N, et al; NEAD Study Group. Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs. N Engl J Med. 2009 Apr 16;360(16):1597-605. 摘要

116. Harden CL, Meador KJ, Pennell PB, et al. Practice parameter update: management issues for women with epilepsy - focus on pregnancy (an evidence-based review): teratogenesis and perinatal outcomes. Neurology. 2009 Jul 14;73(2):133-41.全文  摘要

117. Medicines and Healthcare products Regulatory Agency. Antiepileptic drugs in pregnancy: updated advice following comprehensive safety review. Jan 2021 [internet publication].全文

118. American College of Obstetricians and Gynecologists. Gynecologic management of adolescents and young women with seizure disorders: ACOG Committee Opinion, number 806. Obstet Gynecol. 2020 May;135(5):e213-20.全文  摘要

119. European Medicines Agency. New measures to avoid valproate exposure in pregnancy endorsed. Mar 2018 [internet publication].全文

120. Dreier JW, Bjørk MH, Alvestad S, et al. Prenatal exposure to antiseizure medication and incidence of childhood- and adolescence-onset psychiatric disorders. JAMA Neurol. 2023 Jun 1;80(6):568-77. 摘要

121. Bromley R, Adab N, Bluett-Duncan M, et al. Monotherapy treatment of epilepsy in pregnancy: congenital malformation outcomes in the child. Cochrane Database Syst Rev. 2023 Aug 29;8(8):CD010224.全文  摘要

122. Medicines and Healthcare products Regulatory Agency. Pregabalin (Lyrica): findings of safety study on risks during pregnancy. Apr 2022 [internet publication].全文

123. Bjørk MH, Zoega H, Leinonen MK, et al. Association of prenatal exposure to antiseizure medication with risk of autism and intellectual disability. JAMA Neurol. 2022 Jul 1;79(7):672-81.全文  摘要

124. European Medicines Agency. New measures to avoid topiramate exposure in pregnancy. Oct 2023 [internet publication].全文

125. Medicines and Healthcare products Regulatory Agency. Topiramate (Topamax): start of safety review triggered by a study reporting an increased risk of neurodevelopmental disabilities in children with prenatal exposure. Jul 2022 [internet publication].全文  摘要

126. Athar F, Ehsan M, Farooq M, et al. Adverse fetal and neonatal outcomes following in-utero exposure to oxcarbazepine: a systematic review and meta-analysis. Br J Clin Pharmacol. 2022 Aug;88(8):3600-9.全文  摘要

127. Royal College of Obstetricians and Gynaecologists. Epilepsy in pregnancy (Green-top Guideline No.68). Jun 2016 (updated May 2018) [internet publication].全文

128. Zhu LN, Chen D, Xu D, et al. Newer antiepileptic drugs compared to levetiracetam as adjunctive treatments for uncontrolled focal epilepsy: an indirect comparison. Seizure. 2017 Oct;51:121-32.全文  摘要

129. Harden CL, Pennell PB, Koppel BS, et al; American Academy of Neurology; American Epilepsy Society. Practice parameter update: management issues for women with epilepsy - focus on pregnancy (an evidence-based review): vitamin K, folic acid, blood levels, and breastfeeding. Neurology. 2009 Jul 14;73(2):142-9.全文  摘要

130. Morrow JI, Hunt SJ, Russell AJ, et al. Folic acid use and major congenital malformations in offspring of women with epilepsy: a prospective study from the UK Epilepsy and Pregnancy Register. J Neurol Neurosurg Psychiatry. 2009 May;80(5):506-11. 摘要

131. Harden CL, Hopp J, Ting TY, et al. Practice parameter update: management issues for women with epilepsy - focus on pregnancy (an evidence-based review): obstetrical complications and change in seizure frequency. Neurology. 2009 Jul 14;73(2):126-32.全文  摘要

132. Tomson T, Battino D, Bromley R, et al. Management of epilepsy in pregnancy: a report from the International League Against Epilepsy Task Force on Women and Pregnancy. Epileptic Disord. 2019 Dec 1;21(6):497-517. 摘要

133. Pennell PB, Karanam A, Meador KJ, et al. Antiseizure medication concentrations during pregnancy: results from the Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD) Study. JAMA Neurol. 2022 Apr 1;79(4):370-9.全文  摘要

134. New South Wales Ministry of Health. Infants and children: acute management of seizures. Feb 2016 [internet publication].全文

135. Ambrosetto G, Tassinari CA. Antiepileptic drug treatment of benign childhood epilepsy with rolandic spikes: is it necessary? Epilepsia. 1990 Nov-Dec;31(6):802-5. 摘要

136. Nevitt SJ, Sudell M, Weston J, et al. Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data. Cochrane Database Syst Rev. 2017 Dec 15;(12):CD011412.全文  摘要

137. Schubert-Bast S, Willems LM, Kurlemann G, et al. Postmarketing experience with brivaracetam in the treatment of focal epilepsy in children and adolescents. Epilepsy Behav. 2018 Dec;89:89-93. 摘要

138. Arya R, Giridharan N, Anand V, et al. Clobazam monotherapy for focal or generalized seizures. Cochrane Database Syst Rev. 2018 Jul 11;(7):CD009258.全文  摘要

139. Cao Y, He X, Zhao L, et al. Efficacy and safety of levetiracetam as adjunctive treatment in children with focal onset seizures: a systematic review and meta-analysis. Epilepsy Res. 2019 Jul;153:40-8. 摘要

140. Lattanzi S, Brigo F, Grillo E, et al. Adjunctive eslicarbazepine acetate in pediatric patients with focal epilepsy: a systematic review and meta-analysis. CNS Drugs. 2018 Mar;32(3):189-96. 摘要

141. Kwan P, Brodie MJ. Early identification of refractory epilepsy. N Engl J Med. 2000 Feb 3;342(5):314-9.全文  摘要

142. Schiller Y, Najjar Y. Quantifying the response to antiepileptic drugs: effect of past treatment history. Neurology. 2008 Jan 1;70(1):54-65. 摘要

143. Michaelis R, Tang V, Nevitt SJ, et al. Psychological treatments for people with epilepsy. Cochrane Database Syst Rev. 2020 Sep 7;(8):CD012081.全文

144. Luedke MW, Blalock DV, Goldstein KM, et al. Self-management of epilepsy: a systematic review. Ann Intern Med. 2019 Jul 16;171(2):117-26. 摘要

145. Michaelis R, Tang V, Goldstein LH, et al. Psychological treatments for adults and children with epilepsy: evidence-based recommendations by the International League Against Epilepsy Psychology Task Force. Epilepsia. 2018 Jul;59(7):1282-302. 摘要

146. Sheng J, Liu S, Qin H, et al. Drug-resistant epilepsy and surgery. Curr Neuropharmacol. 2018;16(1):17-28.全文  摘要

147. Engel J Jr, Wiebe S, French J, et al. Practice parameter: temporal lobe and localized neocortical resections for epilepsy. Neurology. 2003 Feb 25;60(4):538-47.全文  摘要

148. West S, Nevitt SJ, Cotton J, et al. Surgery for epilepsy. Cochrane Database Syst Rev. 2019 Jun 25;(6):CD010541.全文  摘要

149. Kohlhase K, Zöllner JP, Tandon N, et al. Comparison of minimally invasive and traditional surgical approaches for refractory mesial temporal lobe epilepsy: a systematic review and meta-analysis of outcomes. Epilepsia. 2021 Apr;62(4):831-45.全文  摘要

150. Grewal SS, Alvi MA, Lu VM, et al. Magnetic resonance-guided laser interstitial thermal therapy versus stereotactic radiosurgery for medically intractable temporal lobe epilepsy: a systematic review and meta-analysis of seizure outcomes and complications. World Neurosurg. 2019 Feb;122:e32-47. 摘要

151. Boon P, De Cock E, Mertens A, et al. Neurostimulation for drug-resistant epilepsy: a systematic review of clinical evidence for efficacy, safety, contraindications and predictors for response. Curr Opin Neurol. 2018 Apr;31(2):198-210. 摘要

152. Panebianco M, Rigby A, Weston J, et al. Vagus nerve stimulation for partial seizures. Cochrane Database Syst Rev. 2015 Apr 3;(4):CD002896.全文  摘要

153. Wang HJ, Tan G, Zhu LN, et al. Predictors of seizure reduction outcome after vagus nerve stimulation in drug-resistant epilepsy. Seizure. 2019 Mar;66:53-60.全文  摘要

154. Li MCH, Cook MJ. Deep brain stimulation for drug-resistant epilepsy. Epilepsia. 2018 Feb;59(2):273-90.全文  摘要

155. Toffa DH, Touma L, El Meskine T, et al. Learnings from 30 years of reported efficacy and safety of vagus nerve stimulation (VNS) for epilepsy treatment: a critical review. Seizure. 2020 Dec;83:104-23.全文  摘要

156. Morris GL 3rd, Gloss D, Buchhalter J, et al. Evidence-based guideline update: vagus nerve stimulation for the treatment of epilepsy: report of the Guideline Development Subcommittee of the American Academy of Neurology. Neurology. 2013 Oct 15;81(16):1453-9. [Re-affirmed 2019.]全文  摘要

157. National Institute for Health and Care Excellence. Deep brain stimulation for refractory epilepsy in adults. Aug 2020 [internet publication].全文

158. US Food and Drug Administration. RNS® System - P100026. Jan 2015 [internet publication].全文

159. Bergey GK, Morrell MJ, Mizrahi EM, et al. Long-term treatment with responsive brain stimulation in adults with refractory partial seizures. Neurology. 2015 Feb 24;84(8):810-7.全文  摘要

160. Heck CN, King-Stephens D, Massey AD, et al. Two-year seizure reduction in adults with medically intractable partial onset epilepsy treated with responsive neurostimulation: final results of the RNS System Pivotal trial. Epilepsia. 2014 Mar;55(3):432-41.全文  摘要

161. Morrell MJ; RNS System in Epilepsy Study Group. Responsive cortical stimulation for the treatment of medically intractable partial epilepsy. Neurology. 2011 Sep 27;77(13):1295-304. 摘要

162. Freeman JM, Kossoff EH, Freeman JB, et al. The ketogenic diet: a treatment for children and others with epilepsy. New York, NY: Demos Medical Publishing; 2006.

163. Martin-McGill KJ, Bresnahan R, Levy RG, et al. Ketogenic diets for drug-resistant epilepsy. Cochrane Database Syst Rev. 2020 Jun 24;6(6):CD001903.全文  摘要

164. Zhang Y, Xu J, Zhang K, et al. The anticonvulsant effects of ketogenic diet on epileptic seizures and potential mechanisms. Curr Neuropharmacol. 2018;16(1):66-70.全文  摘要

165. Gloss D, Pargeon K, Pack A, et al. Antiseizure medication withdrawal in seizure-free patients: practice advisory update summary. Report of the AAN Guideline Subcommittee. Neurology. 2021 Dec 7;97(23):1072-81.全文  摘要

166. Strozzi I, Nolan SJ, Sperling MR, et al. Early versus late antiepileptic drug withdrawal for people with epilepsy in remission. Cochrane Database Syst Rev. 2015 Feb 11;(2):CD001902.全文  摘要

167. Hixson JD. Stopping antiepileptic drugs: when and why? Curr Treat Options Neurol. 2010 Sep;12(5):434-42.全文  摘要

168. Chen H, He H, Xiao Y, et al. Losigamone add-on therapy for focal epilepsy. Cochrane Database Syst Rev. 2019 Dec 11;(12):CD009324.全文  摘要

169. Sperling MR, Klein P, Tsai J. Randomized, double-blind, placebo-controlled phase 2 study of ganaxolone as add-on therapy in adults with uncontrolled partial-onset seizures. Epilepsia. 2017 Apr;58(4):558-64.全文  摘要

170. American Epilepsy Society. AES position statement on cannabis as a treatment for patients with epileptic seizures. Sept 2022 [internet publication].全文

171. Lamberink HJ, Otte WM, Blümcke I, et al. Seizure outcome and use of antiepileptic drugs after epilepsy surgery according to histopathological diagnosis: a retrospective multicentre cohort study. Lancet Neurol. 2020 Sep;19(9):748-57. 摘要

172. Harden C, Tomson T, Gloss D, et al. Practice guideline summary: sudden unexpected death in epilepsy incidence rates and risk factors. Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology. 2017 Apr 25;88(17):1674-80. [Re-affirmed 2020.]全文  摘要

173. Sveinsson O, Andersson T, Carlsson S, et al. The incidence of SUDEP: a nationwide population-based cohort study. Neurology. 2017 Jul 11;89(2):170-7. 摘要

174. Keezer MR, Sisodiya SM, Sander JW. Comorbidities of epilepsy: current concepts and future perspectives. Lancet Neurol. 2016 Jan;15(1):106-15. 摘要

175. Hesdorffer DC, Ishihara L, Mynepalli L, et al. Epilepsy, suicidality, and psychiatric disorders: a bidirectional association. Ann Neurol. 2012 Aug;72(2):184-91. 摘要

176. Maguire MJ, Marson AG, Nevitt SJ. Antidepressants for people with epilepsy and depression. Cochrane Database Syst Rev. 2021 Apr 16;(4):CD010682.全文  摘要

177. ​American Epilepsy Society. Substitution of different formulations of antiseizure medication for the treatment of epilepsy. Aug 2023 [internet publication].全文

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