Whipple 病

Schneider T, Moos V, Loddenkemper C, et al. Whipple's disease: new aspects of pathogenesis and treatment. Lancet Infect Dis. 2008 Mar;8(3):179-90. 摘要

Fenollar F, Puechal X, Raoult D. Whipple's disease. N Engl J Med. 2007 Jan 4;356(1):55-66.

Dobbins WO. Whipple's disease. Springfield, IL: Thomas; 1987.

Louis ED, Lynch T, Kaufmann P, et al. Diagnostic guidelines in central nervous system Whipple's disease. Ann Neurol. 1996 Oct;40(4):561-8. 摘要

Feurle GE, Junga NS, Marth T. Efficacy of ceftriaxone or meropenem as initial therapies in Whipple's disease. Gastroenterology. 2010 Feb;138(2):478-86; quiz 11-2.全文  摘要

Feurle GE, Moos V, Bläker H, et al. Intravenous ceftriaxone, followed by 12 or three months of oral treatment with trimethoprim-sulfamethoxazole in Whipple's disease. J Infect. 2013 Mar;66(3):263-70. 摘要

1. Raoult D, Ogata H, Audic S, et al. Tropheryma whipplei twist: a human pathogenic Actinobacteria with a reduced genome. Genome Res. 2003 Aug;13(8):1800-9.全文  摘要

2. Bentley SD, Maiwald M, Murphy LD, et al. Sequencing and analysis of the genome of the Whipple's disease bacterium Tropheryma whipplei. Lancet. 2003 Feb 22;361(9358):637-44. 摘要

3. Schoniger-Hekele M, Petermann D, Weber B, et al. Tropheryma whipplei in the environment: survey of sewage plant influxes and sewage plant workers. Appl Environ Microbiol. 2007 Mar;73(6):2033-5.全文  摘要

4. Maiwald M, Schuhmacher F, Ditton HJ, et al. Environmental occurrence of the Whipple's disease bacterium (Tropheryma whippelii). Appl Environ Microbiol. 1998 Feb;64(2):760-2.全文  摘要

5. Fenollar F, Trani M, Davoust B, et al. Prevalence of asymptomatic Tropheryma whipplei carriage among humans and nonhuman primates. J Infect Dis. 2008 Mar 15;197(6):880-7.全文  摘要

6. Ehrbar HU, Bauerfeind P, Dutly F, et al. PCR-positive tests for Tropheryma whippelii in patients without Whipple's disease. Lancet. 1999 Jun 26;353(9171):2214. 摘要

7. Amsler L, Bauernfeind P, Nigg C, et al. Prevalence of Tropheryma whipplei DNA in patients with various gastrointestinal diseases and in healthy controls. Infection. 2003 Mar;31(2):81-5. 摘要

8. Maibach RC, Dutly F, Altwegg M. Detection of Tropheryma whipplei DNA in feces by PCR using a target capture method. J Clin Microbiol. 2002 Jul;40(7):2466-71.全文  摘要

9. Zinkernagel AS, Gmur R, Fenner L, et al. Marginal and subgingival plaque: a natural habitat of Tropheryma whipplei? Infection. 2003 Mar;31(2):86-91. 摘要

10. Rolain JM, Fenollar F, Raoult D. False positive PCR detection of Tropheryma whipplei in the saliva of healthy people. BMC Microbiol. 2007 May 29;7:48.全文  摘要

11. Schneider T, Moos V, Loddenkemper C, et al. Whipple's disease: new aspects of pathogenesis and treatment. Lancet Infect Dis. 2008 Mar;8(3):179-90. 摘要

12. Fenollar F, Puechal X, Raoult D. Whipple's disease. N Engl J Med. 2007 Jan 4;356(1):55-66.

13. Dobbins WO 3rd. Is there an immune deficit in Whipple's disease? Dig Dis Sci. 1981 Mar;26(3):247-52. 摘要

14. Dobbins WO. Whipple's disease. Springfield, IL: Thomas; 1987.

15. Gubler JG, Kuster M, Dutly F, et al. Whipple endocarditis without overt gastrointestinal disease: report of four cases. Ann Intern Med. 1999 Jul 20;131(2):112-6. 摘要

16. Weber U, Morf MH, Gubler JG, et al. Spondylodiscitis as the first manifestation of Whipple's disease: a removal worker with chronic low back pain. Clin Rheumatol. 2003 Dec;22(6):443-6. 摘要

17. Pruss H, Katchanov J, Zschenderlein R, et al. A patient with cerebral Whipple disease with gastric involvement but no gastrointestinal symptoms: a consequence of local protective immunity? J Neurol Neurosurg Psychiatry. 2007 Aug;78(8):896-8. 摘要

18. Feurle GE, Moos V, Schinnerling K, et al. The immune reconstitution inflammatory syndrome in Whipple disease: a cohort study. Ann Int Med. 2010 Dec 7;153(11):710-7. 摘要

19. Elchert JA, Mansoor E, Abou-Saleh M, et al. Epidemiology of Whipple's Disease in the USA Between 2012 and 2017: A Population-Based National Study. Dig Dis Sci. 2019 May;64(5):1305-11.全文  摘要

20. Ahmad AI, Wikholm C, Pothoulakis I, et al. Whipple's disease review, prevalence, mortality, and characteristics in the United States: a cross-sectional national inpatient study. Medicine (Baltimore). 2022 Dec 9;101(49):e32231.全文  摘要

21. von Herbay A, Otto HF, Stolte M, et al. Epidemiology of Whipple's disease in Germany: analysis of 110 patients diagnosed in 1965-95. Scand J Gastroenterol. 1997 Jan;32(1):52-7. 摘要

22. Raoult D, Fenollar F, Rolain JM, et al. Tropheryma whipplei in children with gastroenteritis. Emerg Infect Dis. 2010 May;16(5):776-82.全文  摘要

23. Fenollar F, Trape JF, Bassene H, et al. Tropheryma whipplei in fecal samples from children, Senegal. Emerg Infect Dis. 2009 Jun;15(6):922-4.全文  摘要

24. Moos V, Kunkel D, Marth T, et al. Reduced peripheral and mucosal Tropheryma whipplei-specific Th1 response in patients with Whipple's disease. J Immunol. 2006 Aug 1;177(3):2015-22.全文  摘要

25. Bonhomme CJ, Renesto P, Nandi S, et al. Serological microarray for a paradoxical diagnostic of Whipple's disease. Eur J Clin Microbiol Infect Dis. 2008 Oct;27(10):959-68. 摘要

26. Martinetti M, Biagi F, Badulli C, et al. The HLA alleles DRB1*13 and DQB1*06 are associated to Whipple's disease. Gastroenterology. 2009 Jun;136(7):2289-94. 摘要

27. Marth T, Raoult D. Whipple's disease. Lancet. 2003 Jan 18;361(9353):239-46. 摘要

28. Desnues B, Ihrig M, Raoult D, et al. Whipple's disease: a macrophage disease. Clin Vaccine Immunol. 2006 Feb;13(2):170-8.全文  摘要

29. Bai JC, Sen L, Diez R, et al. Impaired monocyte function in patients successfully treated for Whipple's disease. Acta Gastroenterol Latinoam. 1996;26(2):85-9. 摘要

30. Lukacs G, Dobi S, Szabo M. A case of Whipple's disease with repeated operations for ileus and complete cure. Acta Hepatogastroenterol (Stuttg). 1978 Jun;25(3):238-42. 摘要

31. Ghigo E, Capo C, Aurouze M, et al. Survival of Tropheryma whipplei, the agent of Whipple's disease, requires phagosome acidification. Infect Immun. 2002 Mar;70(3):1501-6.全文  摘要

32. Marth T, Roux M, von Herbay A, et al. Persistent reduction of complement receptor 3 alpha-chain expressing mononuclear blood cells and transient inhibitory serum factors in Whipple's disease. Clin Immunol Immunopathol. 1994 Aug;72(2):217-26. 摘要

33. Ectors N, Geboes K, De Vos R, et al. Whipple's disease: a histological, immunocytochemical and electronmicroscopic study of the immune response in the small intestinal mucosa. Histopathology. 1992 Jul;21(1):1-12. 摘要

34. Kalt A, Schneider T, Ring S, et al. Decreased levels of interleukin-12p40 in the serum of patients with Whipple's disease. Int J Colorectal Dis. 2006 Mar;21(2):114-20. 摘要

35. Marth T, Neurath M, Cuccherini BA, et al. Defects of monocyte interleukin 12 production and humoral immunity in Whipple's disease. Gastroenterology. 1997 Aug;113(2):442-8. 摘要

36. Desnues B, Lepidi H, Raoult D, et al. Whipple disease: intestinal infiltrating cells exhibit a transcriptional pattern of M2/alternatively activated macrophages. J Infect Dis. 2005 Nov 1;192(9):1642-6.全文  摘要

37. Moos V, Schmidt C, Geelhaar A, et al. Impaired immune functions of monocytes and macrophages in Whipple's disease. Gastroenterology. 2010 Jan;138(1):210-20. 摘要

38. Marth T, Kleen N, Stallmach A, et al. Dysregulated peripheral and mucosal Th1/Th2 response in Whipple's disease. Gastroenterology. 2002 Nov;123(5):1468-77. 摘要

39. Schoedon G, Goldenberger D, Forrer R, et al. Deactivation of macrophages with interleukin-4 is the key to the isolation of Tropheryma whippelii. J Infect Dis. 1997 Sep;176(3):672-7. 摘要

40. Friedmann AC, Perera GK, Jayaprakasam A, et al. Whipple's disease presenting with symmetrical panniculitis. Br J Dermatol. 2004 Oct;151(4):907-11. 摘要

41. Tarroch X, Vives P, Salas A, et al. Subcutaneous nodules in Whipple's disease. J Cutan Pathol. 2001 Aug;28(7):368-70. 摘要

42. Helliwell TR, Appleton RE, Mapstone NC, et al. Dermatomyositis and Whipple's disease. Neuromuscul Disord. 2000 Jan;10(1):46-51. 摘要

43. Kwee D, Fields JP, King LE Jr. Subcutaneous Whipple's disease. J Am Acad Dermatol. 1987 Jan;16(1 Pt 2):188-90. 摘要

44. Cho C, Linscheer WG, Hirschkorn MA, et al. Sarcoidlike granulomas as an early manifestation of Whipple's disease. Gastroenterology. 1984 Oct;87(4):941-7. 摘要

45. Viteri AL, Stinson JC, Barnes MC, et al. Rod-shaped organism in the liver of a patient with Whipple's disease. Dig Dis Sci. 1979 Jul;24(7):560-4. 摘要

46. Puget M, Iwaz J, Tristan A, et al. Whipple's disease with muscle impairment. Muscle Nerve. 2006 Dec;34(6):794-8. 摘要

47. Misbah SA, Stirzaker D, Ozols B, et al. Anonymous survey of blood donors by polymerase chain reaction for Tropheryma whippelii. QJM. 1999 Jan;92(1):61.全文  摘要

48. Mahnel R, Kalt A, Ring S, et al. Immunosuppressive therapy in Whipple's disease patients is associated with the appearance of gastrointestinal manifestations. Am J Gastroenterol. 2005 May;100(5):1167-73. 摘要

49. Biagi F, Trotta L, Corazza GR. Whipple's disease. Intern Emerg Med. 2012 Oct;7 Suppl 3:S209-13. 摘要

50. Louis ED, Lynch T, Kaufmann P, et al. Diagnostic guidelines in central nervous system Whipple's disease. Ann Neurol. 1996 Oct;40(4):561-8. 摘要

51. Keinath RD, Merrell DE, Vlietstra R, et al. Antibiotic treatment and relapse in Whipple's disease: long-term follow-up of 88 patients. Gastroenterology. 1985 Jun;88(6):1867-73. 摘要

52. Durand DV, Lecomte C, Cathebras P, et al. Whipple disease: clinical review of 52 cases. The SNFMI Research Group on Whipple Disease. Societe Nationale Francaise de Medecine Interne. Medicine (Baltimore). 1997 May;76(3):170-84. 摘要

53. Gerard A, Sarrot-Reynauld F, Liozon E, et al. Neurologic presentation of Whipple disease: report of 12 cases and review of the literature. Medicine (Baltimore). 2002 Nov;81(6):443-57. 摘要

54. Messori A, Di Bella P, Polonara G, et al. An unusual spinal presentation of Whipple disease. AJNR Am J Neuroradiol. 2001 May;22(5):1004-8.全文  摘要

55. Mendel E, Khoo LT, Go JL, et al. Intracerebral Whipple's disease diagnosed by stereotactic biopsy: a case report and review of the literature. Neurosurgery. 1999 Jan;44(1):203-9. 摘要

56. Feurle GE, Utz G, Kies D, et al. Neurological manifestations of Whipple's disease. Schweiz Med Wochenschr. 1976 Nov 20;106(47):1642-6. 摘要

57. Feurle GE, Volk B, Waldherr R. Cerebral Whipple's disease with negative jejunal histology. N Engl J Med. 1979 Apr 19;300(16):907-8. 摘要

58. Fenollar F, Raoult D. Whipple's disease. Clin Vaccine Immunol. 2001;8(1):1-8.全文  摘要

59. Fenollar F, Raoult D. Molecular techniques in Whipple's disease. Expert Rev Mol Diagn. 2001 Sep;1(3):299-309. 摘要

60. Maiwald M, von Herbay A, Persing DH, et al. Tropheryma whippelii DNA is rare in the intestinal mucosa of patients without other evidence of Whipple disease. Ann Intern Med. 2001 Jan 16;134(2):115-9.全文  摘要

61. Misbah SA, Mapstone NP. Whipple's disease revisited. J Clin Pathol. 2000 Oct;53(10):750-5.全文  摘要

62. Krober SM, Kaiserling E, Horny HP, et al. Primary diagnosis of Whipple's disease in bone marrow. Hum Pathol. 2004 Apr;35(4):522-5. 摘要

63. Walter R, Bachmann SP, Schaffner A, et al. Bone marrow involvement in Whipple's disease: rarely reported, but really rare? Br J Haematol. 2001 Mar;112(3):677-9.全文  摘要

64. Lepidi H, Fenollar F, Gerolami R, et al. Whipple's disease: immunospecific and quantitative immunohistochemical study of intestinal biopsy specimens. Hum Pathol. 2003 Jun;34(6):589-96. 摘要

65. Baisden BL, Lepidi H, Raoult D, et al. Diagnosis of Whipple disease by immunohistochemical analysis: a sensitive and specific method for the detection of Tropheryma whipplei (the Whipple bacillus) in paraffin-embedded tissue. Am J Clin Pathol. 2002 Nov;118(5):742-8. 摘要

66. Sinha S, Satishchandra P, Gayathri N, et al. Progressive myoclonic epilepsy: a clinical, electrophysiological and pathological study from South India. J Neurol Sci. 2007 Jan 15;252(1):16-23. 摘要

67. Giuffre B, Parini R, Rizzuti T, et al. Severe neonatal onset of glycogenosis type IV: clinical and laboratory findings leading to diagnosis in two siblings. J Inherit Metab Dis. 2004;27(5):609-19. 摘要

68. Kulczycki J, Collinge J, Lojkowska W, et al. Report on the first Polish case of the Gerstmann-Straussler-Scheinker syndrome. Folia Neuropathol. 2001;39(1):27-31. 摘要

69. von Herbay A, Ditton HJ, Schuhmacher F, et al. Whipple's disease: staging and monitoring by cytology and polymerase chain reaction analysis of cerebrospinal fluid. Gastroenterology. 1997 Aug;113(2):434-41. 摘要

70. Ramzan NN, Loftus E Jr, Burgart LJ, et al. Diagnosis and monitoring of Whipple disease by polymerase chain reaction. Ann Intern Med. 1997 Apr 1;126(7):520-7. 摘要

71. Lagier JC, Lepidi H, Raoult D, et al. Systemic Tropheryma whipplei: clinical presentation of 142 patients with infections diagnosed or confirmed in a reference center. Medicine (Baltimore). 2010 Sep;89(5):337-45.全文  摘要

72. Duss FR, Jaton K, Vollenweider P, et al. Whipple disease: a 15-year retrospective study on 36 patients with positive polymerase chain reaction for Tropheryma whipplei. Clin Microbiol Infect. 2021 Jun;27(6):910.e9-910.e13.全文  摘要

73. Maizel H, Ruffin JM, Dobbins WO 3rd. Whipple's disease: a review of 19 patients from one hospital and a review of the literature since 1950. Medicine (Baltimore). 1970 May;49(3):175-205.

74. Fleming JL, Wiesner RH, Shorter RG. Whipple's disease: clinical, biochemical, and histopathologic features and assessment of treatment in 29 patients. Mayo Clin Proc. 1988 Jun;63(6):539-51. 摘要

75. von Herbay A, Maiwald M, Ditton HJ, et al. Histology of intestinal Whipple's disease revisited: a study of 48 patients. Virchows Arch. 1996 Dec;429(6):335-43. 摘要

76. Kowalczewska M, Fenollar F, Lafitte D, et al. Identification of candidate antigen in Whipple's disease using a serological proteomic approach. Proteomics. 2006 Jun;6(11):3294-3305. 摘要

77. Boulos A, Rolain JM, Raoult D. Antibiotic susceptibility of Tropheryma whipplei in MRC5 cells. Antimicrob Agents Chemother. 2004 Mar;48(3):747-52.全文  摘要

78. Boulos A, Rolain JM, Mallet MN, et al. Molecular evaluation of antibiotic susceptibility of Tropheryma whipplei in axenic medium. J Antimicrob Chemother. 2005 Feb;55(2):178-81.全文  摘要

79. Feurle GE, Junga NS, Marth T. Efficacy of ceftriaxone or meropenem as initial therapies in Whipple's disease. Gastroenterology. 2010 Feb;138(2):478-86; quiz 11-2.全文  摘要

80. Feurle GE, Moos V, Bläker H, et al. Intravenous ceftriaxone, followed by 12 or three months of oral treatment with trimethoprim-sulfamethoxazole in Whipple's disease. J Infect. 2013 Mar;66(3):263-70. 摘要

81. Lagier JC, Fenollar F, Lepidi H, et al. Treatment of classic Whipple's disease: from in vitro results to clinical outcome. J Antimicrob Chemother. 2014 Jan;69(1):219-27. 摘要

82. Schiepatti A, Nicolardi ML, Marone P, et al. Long-term morbidity and mortality in Whipple's disease: a single-center experience over 20 years. Future Microbiol. 2020 Jul;15:847-54. 摘要

83. Fenollar F, Rolain JM, Alric L, et al. Resistance to trimethoprim/sulfamethoxazole and Tropheryma whipplei. Int J Antimicrob Agents. 2009 Sep;34(3):255-9. 摘要

84. Lagier JC, Fenollar F, Lepidi H, et al. Failure and relapse after treatment with trimethoprim/sulfamethoxazole in classic Whipple's disease. J Antimicrob Chemother. 2010 Sep;65(9):2005-12. 摘要

85. Marumganti AR, Murphy TF. Whipple's disease: neurological relapse presenting as headache for two years. J Gen Intern Med. 2008 Dec;23(12):2131-3. 摘要

86. Garas G, Cheng WS, Abrugiato R, et al. Clinical relapse in Whipple's disease despite maintenance therapy. J Gastroenterol Hepatol. 2000 Oct;15(10):1223-6. 摘要