最后审阅: 19 九月 2021
最后更新: 06 八月 2020

小结

定义

病史和体格检查

关键诊断因素

  • 在特定种族或地域人群中易患倾向增加
  • 口腔溃疡
  • 生殖器溃疡
  • 葡萄膜炎
  • 痤疮皮损
  • 结节性红斑
  • 症状持续时间短
  • 血栓性浅静脉炎
  • 前房积脓
  • 卒中
  • 眼痛、视力模糊、畏光或光过敏
  • 记忆减退
  • 头痛、意识模糊或发热
  • 咯血、咳嗽、气短或胸痛
  • 眼红或流泪
  • 言语、平衡或运动功能受损

其他诊断因素

  • 腹部绞痛、腹泻或胃肠道溃疡

危险因素

  • 年龄为 20 至 40 岁
  • 白塞综合征的家族史
  • 遗传易感性

诊断性检查

需考虑的检查

  • 针刺试验
  • 类风湿因子
  • 抗核抗体 (ANA)
  • 抗中性粒细胞胞质抗体
  • HLA-B51
  • 腰椎穿刺:
  • 头颅MRI和增强MRA
  • 结肠镜检查
  • 上消化道内镜检查
  • 高分辨率胸部CT扫描
  • 胸部CTA
  • 肺血管造影术

新兴检查

  • 抗酿酒酵母抗体

治疗流程

撰稿人

作者

Yusuf Yazici, MD
Yusuf Yazici

Clinical Associate Professor of Medicine

New York University School of Medicine

Director

Behcet's Syndrome Center

New York University School of Medicine

NY

利益声明

YY has received research support from Amgen, Celgene, Genentech, and Bristol-Myers Squibb. YY is a consultant for Celgene, Bristol-Myers Squibb, and Amgen.

同行评议者

Izzet Fresko, MD

Associate Professor of Medicine

Department of Rheumatology

Cerrahpasa Medical Faculty

Istanbul

Turkey

利益声明

IF declares that he has no competing interests.

Megan E.B. Clowse, MD, MPH

Assistant Professor of Medicine

Division of Rheumatology and Immunology

Duke University Medical Center

Durham

NC

利益声明

MEBC has received speaking fees from Abbott Pharmaceuticals.

Philip Seo, MD, MHS

Assistant Professor of Medicine

Division of Rheumatology

Johns Hopkins University School of Medicine

Co-Director

Johns Hopkins Vasculitis Center

Baltimore

MD

利益声明

PS declares that he has no competing interests.

内容使用需遵循免责声明