通常随疾病进展而发生，尤其是在穿孔发生之后。 表现为右下腹包块压痛、弛张热、白细胞增多。 超声和计算机体层成像（computed tomography, CT）扫描可显示脓肿。 初始治疗包括静脉使用抗生素和 CT 引导下脓肿引流。 如果临床情况改善，体征和症状完全消退，则不需要进行延期阑尾切除术。[72]Mason RJ. Surgery for appendicitis: is it necessary? Surg Infect (Larchmt). 2008 Aug;9(4):481-8.
http://www.ncbi.nlm.nih.gov/pubmed/18687030?tool=bestpractice.com
[73]Deakin DE, Ahmed I. Interval appendicectomy after resolution of adult inflammatory appendix mass - is it necessary? Surgeon. 2007 Feb;5(1):45-50.
http://www.ncbi.nlm.nih.gov/pubmed/17313128?tool=bestpractice.com
[74]Andersson RE, Petzold MG. Nonsurgical treatment of appendiceal abscess or phlegmon: a systematic review and meta-analysis. Ann Surg. 2007 Nov;246(5):741-8.
http://www.ncbi.nlm.nih.gov/pubmed/17968164?tool=bestpractice.com
如果症状没有完全消退，延期阑尾切除术应在 6 周后进行。[75]Garba ES, Ahmed A. Management of appendiceal mass. Ann Afr Med. 2008 Dec;7(4):200-4.
http://www.annalsafrmed.org/article.asp?issn=1596-3519;year=2008;volume=7;issue=4;spage=200;epage=204;aulast=Garba
http://www.ncbi.nlm.nih.gov/pubmed/19623924?tool=bestpractice.com
有证据显示，对于成人阑尾脓肿，相对于保守治疗，腹腔镜下阑尾切除术可能是一种可行的一线治疗选择；然而，一项系统评价却无法找到证据，证明在阑尾脓肿治疗中，早期阑尾切除术（腹腔镜或开放手术）相对于保守治疗更为获益亦或更为有害。[76]Mentula P, Sammalkorpi H, Leppäniemi A. Laparoscopic surgery or conservative treatment for appendiceal abscess in adults? A randomized controlled trial. Ann Surg. 2015 Aug;262(2):237-42.
http://www.ncbi.nlm.nih.gov/pubmed/25775072?tool=bestpractice.com
[77]Cheng Y, Xiong X, Lu J, et al. Early versus delayed appendicectomy for appendiceal phlegmon or abscess. Cochrane Database Syst Rev. 2017 Jun 2;(6):CD011670.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481778/
http://www.ncbi.nlm.nih.gov/pubmed/28574593?tool=bestpractice.com
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