巨细胞动脉炎 (GCA) 在 50 岁或以上的人群中是血管炎的常见形式。颈动脉颅外分支常常受累。
巨细胞动脉炎 (GCA) 是大中型动脉的肉芽肿性血管炎。它首先累及颈外动脉分支，且是成人最常见的系统性血管炎。巨细胞动脉炎主要发生于 50 岁或以上的人群，更常见于女性。常见风湿性多肌痛症状。巨细胞动脉炎最常见的严重后果是视神经缺血导致的不可逆性失明。巨细胞动脉炎有时也称颞动脉炎、颅动脉炎或肉芽肿性动脉炎。
Kenneth J. Warrington, MD
Professor of Medicine
Mayo Clinic College of Medicine
KJW’s employer receives payments from Eli Lilly and GlaxoSmithKline for his role as investigator in giant cell arteritis clinical trials. KJW has conducted consulting work for Sanofi. KJW is an author of a number of references cited in this topic.
Dr Kenneth J. Warrington wishes to gratefully acknowledge Dr Eric L. Matteson, a previous contributor to this topic. ELM’s employer has received payments from Bristol Meyers Squibb and GlaxoSmithKline for his role as investigator in giant cell arteritis clinical trials; from Novartis for his role in polymyalgia rheumatica clinical trials; and from GlaxoSmithKline for his role as an advisory consultant. ELM is an author and editor for Up To Date and Paradigm, as well as an author of a number of references cited in this topic.
Gene Hunder, MD
Professor of Rheumatology
GH declares that he has no competing interests.
Kuntal Chakravarty, FRCP (London), FRCP (Glasgow), FRCP (Ireland), FACP (USA), FACR (USA)
BHRT University Hospital
KC declares that he has no competing interests.