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小细胞肺癌

最后审阅: 21 Oct 2024
最后更新: 13 Jun 2023

小结

定义

病史和体格检查

关键诊断因素

  • 存在的危险因素
  • 咳嗽
  • 呼吸困难
  • 咯血
  • 胸痛
  • 体重减轻
完整详情

其他诊断因素

  • 年龄 65~74 岁
  • 男性
  • 乏力
  • 肺部检查异常
  • 声嘶
  • 意识模糊
  • 人格改变
  • 恶心和呕吐
  • 头痛
  • 吞咽困难
  • 骨痛和/或骨折
  • 惊厥
  • 颈部或锁骨上淋巴结肿大
  • 面部肿胀
  • 颈部或胸部/腹壁静脉曲张
  • 杵状指
  • 肥大性骨关节病
完整详情

危险因素

  • 吸烟
  • 暴露于烟草环境
  • 氡气暴露
  • 石棉暴露
完整详情

诊断性检查

首要检查

  • 胸部 X 线检查
  • 胸部、肝脏、肾上腺 CT
完整详情

需考虑的检查

  • 支气管镜检查
  • 活检
  • 胸腔穿刺术
  • 胸腔镜
  • 脑部 MRI 或 CT
  • 骨扫描
  • 纵隔镜检查
  • 正电子发射断层成像 (positron emission tomography, PET)
  • 骨髓穿刺和活检
  • 全血细胞计数(FBC)
  • 肝功能检查 (LFT)
  • 血清钠
  • 肾功能
  • 肺功能检查
完整详情

治疗流程

急症处理

初始就诊时:局限性疾病

初始就诊时:广泛性疾病

持续性治疗

6 个月内复发

6 个月后复发

撰稿人

作者

Catherine B. Meador, MD, PhD

Attending Physician

Center for Thoracic Cancers

Instructor in Medicine

Harvard Medical School

Massachusetts General Hospital

Boston

MA

利益声明

CBM declares that she has no competing interests.

鸣谢

Dr Catherine B. Meador would like to gratefully acknowledge Dr Leena Gandhi, Dr Alvin R. Cabrera, Dr Christopher R. Kelsey, Dr Lawrence B. Marks, and Dr Rebecca Suk Heist, previous contributors to this topic.

利益声明

LG, ARC, CRK, and LBM declare that they have no competing interests. RSH has received honouraria for consulting from Novartis, Abbvie, Daichii Sankyo, and EMD Serono. RSH's institution (not RSH) has received research funding from Agios, Abbvie, Exelixis, Daichii Sankyo, Novartis, Lilly, Mirati, Corvus, Incyte, and Genentech Roche.

同行评议者

Alan Neville, MD

Professor

Assistant Dean

Undergraduate Program

McMaster University

Hamilton

Ontario

Canada

利益声明

AN declares that he has no competing interests.

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