全血细胞减少症评估

最后审阅: 22 Oct 2024
最后更新: 16 Nov 2023

小结

鉴别诊断

常见

  • 化疗
  • 放疗
  • 维生素 B12 缺乏症
  • 叶酸缺乏
  • 非血液系统恶性肿瘤骨髓浸润
  • 非霍奇金淋巴瘤
  • 毛细胞白血病
  • 慢性淋巴细胞性白血病
  • 骨髓增生异常
  • 肝硬化
  • 乙型肝炎
  • 丙型肝炎
  • 自身免疫性肝炎
  • HIV
  • 巨细胞病毒感染
  • 分枝杆菌感染
完整详情

不常见

  • 急性髓系白血病
  • 急性淋巴母细胞白血病 (ALL)
  • 多发性骨髓瘤
  • 骨髓纤维化
  • 溶酶体贮积病
  • 神经性厌食症
  • 移植物抗宿主病 (GVHD)
  • 重金属(砷)中毒
  • 镰状细胞贫血(及其他溶血性贫血)中的细小病毒感染
  • 先天性角化不良 (DC)
  • 阵发性睡眠性血红蛋白尿 (PNH)
  • 特发性再生障碍性贫血
  • 范可尼贫血
  • 其他罕见的遗传性血细胞减少症(例如,Diamond-Blackfan 贫血、Shwachman-Diamond 综合征、无巨核细胞性血小板减少症)
  • 特发性门静脉高压症
  • 慢性髓系白血病
  • 布鲁菌病
  • 利什曼病
  • 噬血细胞综合征
  • 药物诱发免疫性全血细胞减少
  • Evans 综合征伴相关中性粒细胞减少
  • 自身免疫性淋巴细胞增生综合征(ALPS)
  • 系统性红斑狼疮
  • 类风湿关节炎
  • 传染性单核细胞增多症
  • Felty 综合征
完整详情

撰稿人

作者

Jeffrey M. Lipton, MD, PhD

Frances and Thomas Gambino Professor of Pediatrics in Hematology/Oncology

Professor of Pediatrics and Molecular Medicine

Donald and Barbara Zucker School of Medicine at Hofstra/Northwell

Professor, The Center for Autoimmune Musculoskeletal and Hematopoietic Diseases

Feinstein Institute for Medical Research

Director, Hematology/Oncology and Stem Cell Transplantation

Cohen Children's Medical Center of New York

Hyde Park

New York

利益声明

JML has been reimbursed by Chiesi Farmaceutici S.p.A as a consultant.

鸣谢

Dr Jeffrey M. Lipton would like to gratefully acknowledge Dr Jeff K. Davies and Dr Eva C. Guinan, the previous contributors to this topic.

利益声明

JKD and ECG declare that they have no competing interests.

同行评议者

Stella Davies, MD, PhD

Professor and Division Director

Cincinnati Children's Hospital Medical Center

Cincinnati

OH

利益声明

SD declares that she has no competing interests.

Drew Provan, BSc, MBChB

Consultant Hematologist

Department of Hematology

The Royal London Hospital

London

UK

利益声明

DP was medical director at GlaxoSmithKline 2005-2006.

Alfred P. Gillio, MD

Director

Bone Marrow Failure Clinic

Tomorrows Children's Institute

Hackensack University Medical Center

Hackensack

NJ

利益声明

APG declares that he has no competing interests.

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