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Rocky Mountain spotted fever

  • 概述
  • 理论
  • 诊断
  • 治疗
  • 随访
  • 资源
最后审阅： 26 Sep 2025
最后更新： 27 Aug 2025

小结

定义

病史和体格检查

关键诊断因素

  • known recent tick exposure or bite
  • triad of fever, rash, and history of tick exposure
  • triad of fever, rash, and headache
  • fever
  • rash
  • headache
  • nausea/vomiting
  • myalgia
  • altered mental status
完整详情

其他诊断因素

  • abdominal pain
  • diarrhea
  • conjunctivitis
  • lymphadenopathy
  • peripheral edema
  • meningismus
  • splenomegaly
  • hepatomegaly
  • jaundice
  • seizures
  • shock
  • coma
完整详情

危险因素

  • illness onset in spring or summer
  • returned travelers from an endemic area
  • residence in or recent exposure to rural area
  • recent (within 2 weeks) outdoor exposure
  • known antecedent tick bite
  • exposure to dogs or pets that spend time outdoors
完整详情

诊断性检查

首要检查

  • CBC
  • serum electrolytes and blood urea nitrogen
  • LFTs
  • indirect immunofluorescent antibody (IFA)
  • blood culture
完整详情

需考虑的检查

  • complement fixation
  • latex agglutination
  • indirect hemagglutination
  • microagglutination
  • enzyme immunoassay
  • lumbar puncture
  • chest x-ray
  • abdominal CT scan
  • immunohistochemistry
  • polymerase chain reaction
完整详情

治疗流程

初步治疗

suspected Rocky Mountain spotted fever (RMSF)

撰稿人

作者

Christopher A. Ohl, MD

Professor of Medicine

Section on Infectious Diseases

Wake Forest School of Medicine

Winston-Salem

NC

Раскрытие информации

CAO declares that he has no competing interests.

Выражение благодарностей

Professor Christopher A. Ohl would like to gratefully acknowledge Dr Steven C. Buckingham, a previous contributor to this topic. SCB is an author of several references cited in this topic. We were made aware that Dr Steven C. Buckingham is now deceased.

Рецензенты

Mary Anne Jackson, MD

Chief

Section of Pediatric Infectious Diseases

Children's Mercy Hospital and Clinics

Professor of Pediatrics

University of Missouri-Kansas City School of Medicine

Kansas City

MO

Раскрытие информации

MAJ is an author of several references cited in this topic.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

Список литературы

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Основные статьи

Biggs HM, Behravesh CB, Bradley KK, et al. Diagnosis and management of tickborne rickettsial diseases: Rocky Mountain spotted fever and other spotted fever group rickettsioses, ehrlichioses, and anaplasmosis - United States. MMWR Recomm Rep. 2016;65:1-44.Полный текст  Аннотация

Centers for Disease Control and Prevention. Ticks: tickborne diseases of the United States. Mar 2025 [internet publication].Полный текст

Статьи, указанные как источники

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