Referências
Principais artigos
Burri C, Brun R. Human African trypanosomiasis. In: Cook GC, Zumla AI, eds. Manson's tropical diseases. Philadelphia, PA: Saunders; 2009:1307-1325.
World Health Organization. Control and surveillance of human African trypanosomiasis. Technical Report Series 984. Geneva, Switzerland: WHO; 2013.Texto completo
Chappuis F, Loutan L, Simarro P, et al. Options for the field diagnosis of human African trypanosomiasis. Clin Microbiol Rev. 2005 Jan;18(1):133-46.Texto completo Resumo
Centers for Disease Control and Prevention. Parasites - African trypanosomiasis (also known as sleeping sickness): resources for health professionals. August 2016 [internet publication].Texto completo
Artigos de referência
1. Burri C, Brun R. Human African trypanosomiasis. In: Cook GC, Zumla AI, eds. Manson's tropical diseases. Philadelphia, PA: Saunders; 2009:1307-1325.
2. World Health Organization. Control and surveillance of human African trypanosomiasis. Technical Report Series 984. Geneva, Switzerland: WHO; 2013.Texto completo
3. Chappuis F, Loutan L, Simarro P, et al. Options for the field diagnosis of human African trypanosomiasis. Clin Microbiol Rev. 2005 Jan;18(1):133-46.Texto completo Resumo
4. Simarro PP, Jannin J, Cattand P. Eliminating human African trypanosomiasis: where do we stand and what comes next? PLoS Med. 2008 Feb;5(2):e55.Texto completo Resumo
5. Stich A, Abel PM, Krishna S. Human African trypanosomiasis. BMJ. 2002 Jul 27;325(7357):203-6. Resumo
6. Brun R, Blum J, Chappuis F, et al. Human African trypanosomiasis. Lancet. 2010 Jan 9;375(9709):148-59. Resumo
7. World Health Organization. ICD-10: International statistical classification of diseases and related health problems; 10th revision. Geneva: World Health Organization, 2010.Texto completo
8. Simarro PP, Cecchi G, Franco JR, et al. Estimating and mapping the population at risk of sleeping sickness. PLoS Negl Trop Dis. 2012;6(10):e1859.Texto completo Resumo
9. World Health Organization. Trypanosomiasis, human African (sleeping sickness). February 2018. [internet publication].Texto completo
10. World Health Organization. Report of a WHO meeting on elimination of African trypanosomiasis (Trypanosoma brucei gambiense). December 2012 [internet publication].Texto completo
11. World Health Organization. WHO outlines criteria to assess elimination of sleeping sickness. July 2018 [internet publication].Texto completo
12. World Health Organization. Report of a WHO informal consultation on sustainable control of human African trypanososmiasis. Geneva: WHO; 2007.Texto completo
13. Simarro PP, Cecchi G, Paone M, et al. The atlas of human African trypanosomiasis: a contribution to global mapping of neglected tropical diseases. Int J Health Geogr. 2010 Nov 1;9:57.Texto completo Resumo
14. Simarro PP, Franco JR, Cecchi G, et al. Human African Trypanosomiasis in non-endemic countries (2000-2010). J Travel Med. 2012 Jan-Feb;19(1):44-53. Resumo
15. World Health Organization. Human African trypanosomiasis (sleeping sickness): epidemiological update. Wkly Epidemiol Rec. 2006 Feb 24;81(8):71-80.Texto completo Resumo
16. Moore AC. Human African trypanosomiasis: a reemerging public health threat. In: Scheld WM, Murray BE, Hughes JM, eds. Emerging infections 6. Washington, DC: ASM; 2004:143-157.
17. Duggan AJ, Hutchinson MP. Sleeping sickness in Europeans: a review of 109 cases. J Trop Med Hyg. 1966 Jun;69(6):124-31. Resumo
18. Truc P, Jamonneau V, N'Guessan P, et al. Trypanosoma brucei ssp. and T. congolense: mixed human infection in Côte d'Ivoire. Trans R Soc Trop Med Hyg. 1998 Sep-Oct;92(5):537-8. Resumo
19. Joshi PP, Shegokar VR, Powar RM, et al. Human trypanosomiasis caused by Trypanosoma evansi in India: the first case report. Am J Trop Med Hyg. 2005 Sep;73(3):491-5.Texto completo Resumo
20. Vanhollebeke B, Truc P, Poelvoorde P, et al. Human Trypanosoma evansi infection linked to a lack of apolipoprotein L-1. N Engl J Med. 2006 Dec 28;355(26):2752-6.Texto completo Resumo
21. Deborggraeve S, Koffi M, Jamonneau V, et al. Molecular analysis of archived blood slides reveals an atypical human Trypanosoma infection. Diagn Microbiol Infect Dis. 2008 Aug;61(4):428-33. Resumo
22. Vanhamme L, Paturiaux-Hanocq F, Poelvoorde P, et al. Apolipoprotein L-I is the trypanosome lytic factor of human serum. Nature. 2003 Mar 6;422(6927):83-7. Resumo
23. Verma A, Manchanda S, Kumar N, et al. Trypanosoma lewisi or T. lewisi-like infection in a 37 day old Indian infant. Am J Trop Med Hyg. 2011 Aug;85(2):221-4. doi: Resumo
24. Truc P, Büscher P, Cuny G, et al. Atypical human infections by animal trypanosomes. PLoS Negl Trop Dis. 2013 Sep 12;7(9):e2256.Texto completo Resumo
25. Uzureau P, Uzureau S, Lecordier L, et al. Mechanism of Trypanosoma brucei gambiense resistance to human serum. Nature. 2013 Sep 19;501(7467):430-4. Resumo
26. Herwaldt BL, Juranek DD. Laboratory-acquired malaria, leishmaniasis, trypanosomiasis, and toxoplasmosis. Am J Trop Med Hyg. 1993 Mar;48(3):313-23. Resumo
27. Rocha G, Martins A, Gama G, et al. Possible cases of sexual and congenital transmission of sleeping sickness. Lancet. 2004 Jan 17;363(9404):247. Resumo
28. Lindner AK, Priotto G. The unknown risk of vertical transmission in sleeping sickness - a literature review. PLoS Negl Trop Dis. 2010 Dec 21;4(12):e783.Texto completo Resumo
29. Vickerman K. Developmental cycles and biology of pathogenic trypanosomes. Br Med Bull. 1985 Apr;41(2):105-14. Resumo
30. Pays E, Nolan DP. Expression and function of surface proteins in Trypanosoma brucei. Mol Biochem Parasitol. 1998 Mar 1;91(1):3-36. Resumo
31. Pays E. Antigenic variation in African trypanosomes. In: Dumas M, Bouteille B, Buguet A, eds. Progress in human African trypanosomiasis, sleeping sickness. Paris: Springer; 1999:31-52.
32. Lejon V, Reiber H, Legros D, et al. Intrathecal immune response pattern for improved diagnosis of central nervous system involvement in trypanosomiasis. J Infect Dis. 2003 May 1;187(9):1475-83. Resumo
33. Bisser S, Lejon V, Preux PM, et al. Blood-cerebrospinal fluid barrier and intrathecal immunoglobulins compared to field diagnosis of central nervous system involvement in sleeping sickness. J Neurol Sci. 2002 Jan 15;193(2):127-35. Resumo
34. Lejon V, Lardon J, Kenis G, et al. Interleukin (IL)-6, IL-8 and IL-10 in serum and CSF of Trypanosoma gambiense sleeping sickness patients before and after treatment. Trans R Soc Trop Med Hyg. 2002 May-Jun;96(3):329-33. Resumo
35. MacLean L, Odiit M, Sternberg JM. Intrathecal cytokine responses in Trypanosoma brucei rhodesiense sleeping sickness patients. Trans R Soc Trop Med Hyg. 2006 Mar;100(3):270-5. Resumo
36. Courtioux B, Pervieux L, Gedeao V, et al. Increased CXCL-13 levels in human African trypanosomiasis meningo-encephalitis. Trop Med Int Health. 2009 May;14(5):529-34. Resumo
37. Hainard A, Tiberti N, Robin X, et al. A combined CXCL10, CXCL8 and H-FABP panel for the staging of human African trypanosomiasis patients. PLoS Negl Trop Dis. 2009 Jun 16;3(6):e459.Texto completo Resumo
38. Sternberg J. Human African trypanosomiasis: clinical presentation and immune response. Parasite Immunol. 2004 Nov-Dec;26(11-12):469-76. Resumo
39. Kennedy PG. The continuing problem of human African trypanosomiasis (sleeping sickness). Ann Neurol. 2008 Aug;64(2):116-26. Resumo
40. Sholdt LL, Schreck CE, Mwangelwa MI, et al. Evaluations of permethrin-impregnated clothing and three topical repellent formulations of DEET against tsetse flies in Zambia. Med Vet Entomol. 1989 Apr;3(2):153-8. Resumo
41. Chappuis F, Stivanello E, Adams K, et al. Card agglutination test for trypanosomiasis (CATT) end-dilution titer and cerebrospinal fluid cell count as predictors of human African trypanosomiasis (Trypanosoma brucei gambiense) among serologically suspected individuals in Southern Sudan. Am J Trop Med Hyg. 2004 Sep;71(3):313-7.Texto completo Resumo
42. Urech K, Neumayr A, Blum J. Sleeping sickness in travelers - do they really sleep? PLoS Negl Trop Dis. 2011 Nov;5(11):e1358.Texto completo Resumo
43. Odiit M, Shaw A, Welburn SC, et al. Assessing the patterns of health-seeking behaviours and awareness among sleeping-sickness patients in eastern Uganda. Ann Trop Med Parasitol. 2004 Jun;98(4):339-48. Resumo
44. Bukachi SA, Wandibba S, Nyamongo IK. The treatment pathways followed by cases of human African trypanosomiasis in western Kenya and eastern Uganda. Ann Trop Med Parasitol. 2009 Apr;103(3):211-20. Resumo
45. Checchi F, Filipe JA, Haydon DT, et al. Estimates of the duration of the early and late stage of gambiense sleeping sickness. BMC Infect Dis. 2008 Feb 8;8:16.Texto completo Resumo
46. Odiit M, Kanshme F, Enyaru JCK. Duration of symptoms and case fatality of sleeping sickness caused by Trypanosoma brucei rhodesiense in Tororo, Uganda. East Afr Med J. 1997 Dec;74(12):792-5. Resumo
47. Cottle LE, Peters JR, Hall A, et al. Multiorgan dysfunction caused by travel-associated African trypanosomiasis. Emerg Infect Dis. 2012 Feb;18(2):287-9.Texto completo Resumo
48. Greenwood BM, Whittle HC. The pathogenesis of sleeping sickness. Trans R Soc Trop Med Hyg. 1980;74(6):716-25. Resumo
49. Sullivan L, Wall SJ, Carrington M, et al. Proteomic selection of immunodiagnostic antigens for human African trypanosomiasis and generation of a prototype lateral flow immunodiagnostic device. PLoS Negl Trop Dis. 2013;7(2):e2087.Texto completo Resumo
50. Büscher P, Gilleman Q, Lejon V. Rapid diagnostic test for sleeping sickness. N Engl J Med. 2013 Mar 14;368(11):1069-70.Texto completo Resumo
51. Büscher P, Mertens P, Leclipteux T, et al. Sensitivity and specificity of HAT Sero-K-SeT, a rapid diagnostic test for serodiagnosis of sleeping sickness caused by Trypanosoma brucei gambiense: a case-control study. Lancet Glob Health. 2014 Jun;2(6):e359-63.Texto completo Resumo
52. Bisser S, Lumbala C, Nguertoum E, et al. Sensitivity and specificity of a prototype rapid diagnostic test for the detection of Trypanosoma brucei gambiense infection: a multi-centric prospective study. PLoS Negl Trop Dis. 2016 Apr 8;10(4):e0004608.Texto completo Resumo
53. Miezan TW, Meda AH, Doua F, et al. Evaluation of the parasitologic techniques used in the diagnosis of human Trypanosoma gambiense trypanosomiasis in the Ivory Coast [in French]. Bull Soc Pathol Exot. 1994;87(2):101-4. Resumo
54. Lutumba P, Robays J, Miaka C, et al. Validity, cost and feasibility of the mAECT and CTC confirmation tests after diagnosis of African of sleeping sickness [in French]. Trop Med Int Health. 2006 Apr;11(4):470-8. Resumo
55. Camara M, Camara O, Ilboudo H, et al. Sleeping sickness diagnosis: use of buffy coats improves the sensitivity of the mini anion exchange centrifugation test. Trop Med Int Health. 2010 Jul;15(7):796-9.Texto completo Resumo
56. Mumba Ngoyi D, Ali Ekangu R, Mumvemba Kodi MF, et al. Performance of parasitological and molecular techniques for the diagnosis and surveillance of gambiense sleeping sickness. PLoS Negl Trop Dis. 2014 Jun 12;8(6):e2954.Texto completo Resumo
57. Simarro PP, Ruiz JA, Franco JR, et al. Attitude towards CATT-positive individuals without parasitological conformation in the African trypanosomiasis (T b gambiense) focus of Quiçama (Angola). Trop Med Int Health. 1999 Dec;4(12):858-61.Texto completo Resumo
58. Inojosa WO, Augusto I, Bisoffi Z, et al. Diagnosing human African trypanosomiasis in Angola using card agglutination test: observational study of active and passive case finding strategies. BMJ. 2006;332:1479-1483.Texto completo Resumo
59. Kager PA, Schipper HG, Stam J, et al. Magnetic resonance imaging findings in human African trypanosomiasis: a four-year follow-up study in a patient and review of the literature. Am J Trop Med Hyg. 2009 Jun;80(6):947-52. Resumo
60. Van Meirvenne N, Magnus E, Büscher P. Evaluation of variant specific trypanolysis tests for serodiagnosis of human infections with Trypanosoma brucei gambiense. Acta Trop. 1995 Dec;60(3):189-99. Resumo
61. Jamonneau V, Bucheton B, Kaboré J, et al. Revisiting the immune trypanolysis test to optimise epidemiological surveillance and control of sleeping sickness in West Africa. PLoS Negl Trop Dis. 2010 Dec 21;4(12):e917.Texto completo Resumo
62. Tiberti N, Hainard A, Lejon V, et al. Cerebrospinal fluid neopterin as marker of the meningo-encephalitic stage of Trypanosoma brucei gambiense sleeping sickness. PLoS One. 2012;7:e40909.Texto completo Resumo
63. Amin DN, Mumba Ngoyi D, Nhkwachi GM, et al. Identification of stage biomarkers for human African trypanosomiasis. Am J Trop Med Hyg. 2010 Jun;82(6):983-90.Texto completo Resumo
64. Tiberti N, Lejon V, Hainard A, et al. Neopterin is a cerebrospinal fluid marker for treatment outcome evaluation in patients affected by Trypanosoma brucei gambiense sleeping sickness. PLoS Negl Trop Dis. 2013;7(2):e2088.Texto completo Resumo
65. Simon F, Mura M, Pagès F, et al. Urban transmission of human African trypanosomiasis, Gabon. Emerg Infect Dis. 2012 Jan;18(1):165-7.Texto completo Resumo
66. Buguet A, Bourdon L, Bouteille B, et al. The duality of sleeping sickness: focusing on sleep. Sleep Med Rev. 2001 Apr;5(2):139-153. Resumo
67. Blum JA, Zellweger MJ, Burri C, et al. Cardiac involvement in African and American trypanosomiasis. Lancet Infect Dis. 2008 Oct;8(10):631-41. Resumo
68. Blum JA, Schmid C, Burri C, et al. Cardiac alterations in human African trypanosomiasis (T b gambiense) with respect to the disease stage and antiparasitic treatment. PLoS Negl Trop Dis. 2009;3(2):e383.Texto completo Resumo
69. Whittle HC, Greenwood BM, Bidwell DE, et al. IgM and antibody measurement in the diagnosis and management of Gambian trypanosomiasis. Am J Trop Med Hyg. 1977 Nov;26(6 Pt 1):1129-34. Resumo
70. Lambert PH, Berney M, Kazyumba G. Immune complexes in serum and in cerebrospinal fluid in African trypanosomiasis: correlation with polyclonal B cell activation and with intracerebral immunoglobulin synthesis. J Clin Invest. 1981 Jan;67(1):77-85.Texto completo Resumo
71. Wellde BT, Chumo DA, Reardon MJ, et al. Presenting features of Rhodesian sleeping sickness patients in the Lambwe Valley, Kenya. Ann Trop Med Parasitol. 1989 Aug;83 Suppl 1:73-89. Resumo
72. Bisser S, Bouteille B, Sarda J, et al. Contribution of biochemical tests in the diagnosis of the nervous phase of human African trypanosomiasis [in French]. Bull Soc Pathol Exot. 1997;90(5):321-6. Resumo
73. Apted FIC. Clinical manifestations and diagnosis of sleeping sickness. In: Mulligan HW, ed. The African trypanosomiases. London: George Allen and Unwin Ltd; 1970:661-683.
74. Magnus E, Vervoort T, Van Meirvenne N. A card-agglutination test with stained trypanosomes (C.A.T.T.) for the serological diagnosis of T. b. gambiense trypanosomiasis. Ann Soc Belg Med Trop. 1978;58(3):169-76. Resumo
75. Dukes P, Gibson WC, Gashumba JK, et al. Absence of the LiTat 1.3 (CATT antigen) gene in Trypanosoma brucei gambiense stocks from Cameroon. Acta Trop. 1992 Jun;51(2):123-34. Resumo
76. Paquet C, Ancelle T, Gastellu-Etchegorry M, et al. Persistence of antibodies to Trypanosoma brucei gambiense after treatment of human trypanosomiasis in Uganda. Lancet. 1992 Jul 25;340(8813):250. Resumo
77. Miezan TW, Dje NN, Doua F, et al. Human African trypanosomiasis in Ivory Coast: biological characteristics after treatment. 812 cases treated in the Daloa focus (Ivory Coast) [in French]. Bull Soc Pathol Exot. 2002 Dec;95(5):362-5. Resumo
78. Lejon V, Ngoyi DM, Boelaert M, et al. A CATT negative result after treatment for human African trypanosomiasis is no indication for cure. PLoS Negl Trop Dis. 2010 Jan 26;4(1):e590. Resumo
79. Jamonneau V, Camara O, Ilboudo H, et al. Accuracy of individual rapid tests for serodiagnosis of gambiense sleeping sickness in West Africa. PLoS Negl Trop Dis. 2015 Feb 2;9(2):e0003480.Texto completo Resumo
80. Simarro PP, Franco JR, Ndongo P. Field evaluation of several serological screening tests for sleeping sickness (T b gambiense). Bull Liais Doc OCEAC. 1999;32:28-33.
81. Kegels G, Criel B, van Lerberghe W, et al. Screening for Trypanosoma brucei gambiense antibodies with the indirect fluorescent antibody test (IFAT). Ann Soc Belg Med Trop. 1992 Dec;72(4):271-81. Resumo
82. Dukes P, Rickman LR, Killick-Kendrick R, et al. A field comparison of seven diagnostic techniques for human trypanosomiasis in the Luangwa Valley, Zambia. Tropenmed Parasitol. 1984 Sep;35(3):141-7. Resumo
83. Wellde BT, Chumo DA, Reardon MJ, et al. Diagnosis of Rhodesian sleeping sickness in the Lambwe Valley (1980-1984). Ann Trop Med Parasitol. 1989 Aug;83 Suppl 1:63-71. Resumo
84. Bailey NM, Cunningham MP, Kimber CD. The indirect fluorescent antibody technique applied to dried blood, for use as a screening test in the diagnosis of human trypanosomiasis in Africa. Trans R Soc Trop Med Hyg. 1967;61(5):696-700. Resumo
85. Roffi J, Carrie J, Garre MT, et al. Immunoenzymatic detection of human African trypanosomiasis using dried blood samples [in French]. Bull Soc Pathol Exot. 1980 Jan-Feb;73(1):67-74. Resumo
86. Vervoort T, Magnus E, Van Meirvenne N. Enzyme-linked immunosorbent assay (ELISA) with variable antigen for serodiagnosis of T b gambiense trypanosomiasis. Ann Soc Belg Med Trop. 1978;58(3):177-83. Resumo
87. Mangenot M, Chaize J, Desfontaine M, et al. Comparative value of ELISA technique and immunofluorescence for the detection in the foci of human African trypanosomiasis [in French]. Med Trop. 1979 Sep-Oct;39(5):527-30. Resumo
88. Lejon V, Jamonneau V, Solano P, et al. Detection of trypanosome-specific antibodies in saliva, towards non-invasive serological diagnosis of sleeping sickness. Trop Med Int Health. 2006 May;11(5):620-7.Texto completo Resumo
89. Woo PT. The haematocrit centrifuge technique for the diagnosis of African trypanosomiasis. Acta Trop. 1970;27(4):384-6. Resumo
90. Bailey JW, Smith DH. The use of the acridine orange QBC technique in the diagnosis of African trypanosomiasis. Trans R Soc Trop Med Hyg. 1992 Nov-Dec;86(6):630. Resumo
91. Truc P, Bailey JW, Doua F, et al. A comparison of parasitological methods for the diagnosis of Gambian trypanosomiasis in an area of low endemicity in Côte d'Ivoire. Trans R Soc Trop Med Hyg. 1994 Jul-Aug;88(4):419-21. Resumo
92. Büscher P, Mumba Ngoyi D, Kaboré J, et al. Improved models of mini Anion Exchange Centrifugation Technique (mAECT) and Modified Single Centrifugation (MSC) for sleeping sickness diagnosis and staging. PLoS Negl Trop Dis. 2009 Nov 24;3(11):e471.Texto completo Resumo
93. Lumsden WH, Kimber CD, Evans DA, et al. Trypanosoma brucei: miniature anion-exchange centrifugation technique for detection of low parasitaemias: adaptation for field use. Trans R Soc Trop Med Hyg. 1979;73(3):312-7. Resumo
94. Boda C, Courtioux B, Roques P, et al. Immunophenotypic lymphocyte profiles in human African trypanosomiasis. PLOS One. 2009 Jul 8;4(7):e6184.Texto completo Resumo
95. Cattand P, Miézan BT, de Raadt P. Human African trypanosomiasis: use of double centrifugation of cerebrospinal fluid to detect trypanosomes. Bull World Health Organ. 1988;66(1):83-6.Texto completo Resumo
96. Miezan TW, Meda AH, Doua F, et al. Single centrifugation of cerebrospinal fluid in a sealed pasteur pipette for simple, rapid and sensitive detection of trypanosomes. Trans R Soc Trop Med Hyg. 2000 May-Jun;94(3):293. Resumo
97. Mumba Ngoyi D, Menten J, Pyana PP, et al. Stage determination in sleeping sickness: comparison of two cell counting and two parasite detection techniques. Trop Med Int Health. 2013 Jun;18(6):778-82.Texto completo Resumo
98. Lejon V, Büscher P. Cerebrospinal fluid in human African trypanosomiasis: a key to diagnosis, therapeutic decision and post-treatment follow-up. Trop Med Int Health. 2005 May;10(5):395-403.Texto completo Resumo
99. Moser DR, Cook GA, Ochs DE, et al. Detection of Trypanosoma congolense and Trypanosoma brucei subspecies by DNA amplification using the polymerase chain reaction. Parasitology. 1989 Aug;99 Pt 1:57-66. Resumo
100. Becker S, Franco JR, Simarro PP, et al. Real-time PCR for detection of Trypanosoma brucei in human blood samples. Diagn Microbiol Infect Dis. 2004 Nov;50(3):193-9. Resumo
101. Kabiri M, Franco JR, Simarro PP, et al. Detection of Trypanosoma brucei gambiense in sleeping sickness suspects by PCR amplification of expression-site-associated genes 6 and 7. Trop Med Int Health. 1999 Oct;4(10):658-61.Texto completo Resumo
102. Deborggraeve S, Claes F, Laurent T, et al. Molecular dipstick test for diagnosis of sleeping sickness. J Clin Microbiol. 2006 Aug;44(8):2884-9.Texto completo Resumo
103. Radwanska M, Chamekh M, Vanhamme L, et al. The serum resistance-associated gene as a diagnostic tool for the detection of Trypanosoma brucei rhodesiense. Am J Trop Med Hyg. 2002 Dec;67(6):684-90. Resumo
104. Welburn SC, Picozzi K, Fevre EM, et al. Identification of human-infective trypanosomes in animal reservoir of sleeping sickness in Uganda by means of serum-resistance-associated (SRA) gene. Lancet. 2001 Dec 15;358(9298):2017-9. Resumo
105. Picozzi K, Fèvre EM, Odiit M, et al. Sleeping sickness in Uganda: a thin line between two fatal diseases. BMJ. 2005 Nov 26;331(7527):1238-41.Texto completo Resumo
106. Radwanska M, Claes F, Magez S, et al. Novel primer sequences for polymerase chain reaction-based detection of Trypanosoma brucei gambiense. Am J Trop Med Hyg. 2002 Sep;67(3):289-95.Texto completo Resumo
107. Jamonneau V, Solano P, Garcia A, et al. Stage determination and therapeutic decision in human African trypanosomiasis: value of PCR and IgM quantification on the cerebrospinal fluid of sleeping sickness patients in Côte d'Ivoire. Trop Med Int Health. 2003 Jul;8(7):589-94.Texto completo Resumo
108. Kirchhoff LV. Use of a PCR assay for diagnosing African trypanosomiasis of the CNS: a case report. Cent Afr J Med. 1998 May;44(5):134-6. Resumo
109. Truc P, Jamonneau V, Cuny G, et al. Use of polymerase chain reaction in human African trypanosomiasis stage determination and follow-up. Bull World Health Organ. 1999;77(9):745-8.Texto completo Resumo
110. Deborggraeve S, Lejon V, Ekangu RA, et al. Diagnostic accuracy of PCR in gambiense sleeping sickness diagnosis, staging and post-treatment follow-up: a 2-year longitudinal study. PLoS Negl Trop Dis. 2011 Feb 22;5(2):e972Texto completo Resumo
111. Kuboki N, Inoue N, Sakurai T, et al. Loop-mediated isothermal amplification for detection of African trypanosomes. J Clin Microbiol. 2003 Dec;41(12):5517-24.Texto completo Resumo
112. Njiru ZK, Mikosza AS, Matovu E, et al. African trypanosomiasis: sensitive and rapid detection of the sub-genus Trypanozoon by loop-mediated isothermal amplification (LAMP) of parasite DNA. Int J Parasitol. 2008 Apr;38(5):589-99. Resumo
113. Mugasa CM, Schoone GJ, Ekangu RA, et al. Detection of Trypanosoma brucei parasites in blood samples using real-time nucleic acid sequence-based amplification. Diagn Microbiol Infect Dis. 2008 Aug;61(4):440-5. Resumo
114. Matovu E, Mugasa CM, Ekangu RA, et al. Phase II evaluation of sensitivity and specificity of PCR and NASBA followed by oligochromatography for diagnosis of human African trypanosomiasis in clinical samples from D.R. Congo and Uganda. PLoS Negl Trop Dis. 2010 Jul 6;4(7):e737. Resumo
115. Njiru ZK, Traub R, Ouma JO, et al. Detection of group 1 trypanosoma brucei gambiense by loop-mediated isothermal amplification. J Clin Microbiol. 2011 Apr;49(4):1530-6.Texto completo Resumo
116. Wastling SL, Picozzi K, Kakembo AS, et al. LAMP for human African trypanosomiasis: a comparative study of detection formats. PLoS Negl Trop Dis. 2010 Nov 2;4(11):e865.Texto completo Resumo
117. González-Andrade P, Camara M, Ilboudo H, et al. Diagnosis of trypanosomatid infections: targeting the spliced leader RNA. J Mol Diagn. 2014 Jul;16(4):400-4. Resumo
118. Mugasa CM, Adams ER, Boer KR, et al. Diagnostic accuracy of molecular amplification tests for human African trypanosomiasis - systematic review. PLoS Negl Trop Dis. 2012 Jan;6(1):e1438.Texto completo Resumo
119. Deborggraeve S, Büscher P. Molecular diagnostics for sleeping sickness: what is the benefit for the patient? Lancet Infect Dis. 2010 Jun;10(6):433-9. Resumo
120. Deborggraeve S, Büscher P. Recent progress in molecular diagnosis of sleeping sickness. Expert Rev Mol Diagn. 2012 Sep;12(7):719-30. Resumo
121. Mitashi P, Hasker E, Mumba Ngoyi D, et al. Diagnostic accuracy of Loopamp Trypanosoma brucei detection kit for diagnosis of human African trypanosomiasis in clinical samples. PLos Negl Trop Dis. 2013 Oct 17;7(10):e2504.Texto completo Resumo
122. Lejon V, Sindic C, Van Antwerpen MP, et al. Human African trypanosomiasis: quantitative and qualitative assessment of intrathecal immune response. Eur J Neurol. 2003 Nov;10(6):711-9. Resumo
123. Gillet P, Mumba Ngoyi D, Lukuka A, et al. False positivity of non-targeted infections in malaria rapid diagnostic tests: the case of human African trypanosomiasis. PLoS Negl Trop Dis. 2013 Apr 25;7(4):e2180.Texto completo Resumo
124. Priotto G, Pinoges L, Fursa IB, et al. Safety and effectiveness of first line eflornithine for Trypanosoma brucei gambiense sleeping sickness in Sudan: cohort study. BMJ. 2008 Mar 29;336(7646):705-8.Texto completo Resumo
125. Lejon V, Ngoyi DM, Ilunga M, et al. Low specificities of HIV diagnostic tests caused by Trypanosoma brucei gambiense sleeping sickness. J Clin Microbiol. 2010 Aug;48(8):2836-9. Resumo
126. Sahlas DJ, MacLean JD, Janevski J, et al. Clinical problem-solving: out of Africa. N Engl J Med. 2002 Sep 5;347(10):749-53. Resumo
127. Sindato C, Kibona SN, Nkya GM, et al. Challenges in the diagnosis and management of sleeping sickness: a case report. Tanzania J Health Res. 2008 Jul;10(3):177-81. Resumo
128. Louis FJ, Kohange Tongue L, Ebo'O Eyenga V, et al. Organizing an active screening campaign for human African trypanosomiasis due to Trypanosoma brucei gambiense [in French]. Med Trop. 2008 Feb;68(1):11-6. Resumo
129. Checchi F, Chappuis F, Karunakara U, et al. Accuracy of five algorithms to diagnose gambiense human African trypanosomiasis. PLoS Negl Trop Dis. 2011 Jul;5(7):e1233.Texto completo Resumo
130. Franco JR, Simarro PP, Diarra A, et al. The journey towards elimination of gambiense human African trypanosomiasis: not far, nor easy. Parasitology. 2014 May;141(6):748-60. Resumo
131. Franco JR, Simarro PP, Diarra A, et al. Epidemiology of human African trypanosomiasis. Clin Epidemiol. 2014 Aug 6;6:257-75.Texto completo Resumo
132. Van Nieuwenhove S, Kande Betu-Ku-Mesu V, Mansinsa Diabakana P, et al. Sleeping sickness resurgence in the DRC: the past decade. Trop Med Int Health. 2001 May;6(5):335-41.Texto completo Resumo
133. Checchi F, Filipe JA, Barrett MP, et al. The natural progression of gambiense sleeping sickness: what is the evidence? PLoS Negl Trop Dis. 2008;2(12):e303.Texto completo Resumo
134. Jamonneau V, Ilboudo H, Kaboré J, et al. Untreated human infections by Trypanosoma brucei gambiense are not 100% fatal. PLoS Negl Trop Dis. 2012;6(6):e1691.Texto completo Resumo
135. Bucheton B, MacLeod A, Jamonneau V. Human host determinants influencing the outcome of Trypanosoma brucei gambiense infections. Parasite Immunol. 2011 Aug;33(8):438-47. Resumo
136. Pepin J, Milord F. The treatment of human African trypanosomiasis. Adv Parasitol. 1994;33:1-47. Resumo
137. Barrett MP, Boykin DW, Brun R, et al. Human African trypanosomiasis: pharmacological re-engagement with a neglected disease. Br J Pharmacol. 2007 Dec;152(8):1155-71.Texto completo Resumo
138. Delespaux V, de Koning HP. Drugs and drug resistance in African trypanosomiasis. Drug Resist Updat. 2007 Feb-Apr;10(1-2):30-50. Resumo
139. Simarro PP, Franco J, Diarra A, et al. Update on field use of the available drugs for the chemotherapy of human African trypanosomiasis. Parasitology. 2012 Jun;139(7):842-6. Resumo
140. Centers for Disease Control and Prevention. Parasites - African trypanosomiasis (also known as sleeping sickness): resources for health professionals. August 2016 [internet publication].Texto completo
141. Balasegaram M, Harris S, Checchi F, et al. Treatment outcomes and risk factors for relapse in patients with early-stage human African trypanosomiasis (HAT) in the Republic of the Congo. Bull World Health Organ. 2006 Oct;84(10):777-82. Resumo
142. Balasegaram M, Harris S, Checchi F, et al. Melarsoprol versus eflornithine for treating late-stage Gambian trypanosomiasis in the Republic of the Congo. Bull World Health Organ. 2006 Oct;84(10):783-91. Resumo
143. Chappuis F. Melarsoprol-free drug combinations for second-stage Gambian sleeping sickness: the way to go. Clin Infect Dis. 2007 Dec 1;45(11):1443-5. Resumo
144. Balasegaram M, Young H, Chappuis F, et al. Effectiveness of melarsoprol and eflornithine as first-line regimens for gambiense sleeping sickness in nine Medecins Sans Frontieres programmes. Trans R Soc Trop Med Hyg. 2009 Mar;103(3):280-90. Resumo
145. Lutje V, Seixas J, Kennedy A. Chemotherapy for second-stage human African trypanosomiasis. Cochrane Database Syst Rev. 2013 Jun 28;(6):CD006201.Texto completo Resumo
146. Priotto G, Kasparian S, Mutombo W, et al. Nifurtimox-eflornithine combination therapy for second-stage African Trypanosoma brucei gambiense trypanosomiasis: a multicentre, randomised, phase III, non-inferiority trial. Lancet. 2009 Jul 4;374(9683):56-64. Resumo
147. Chappuis F, Udayraj N, Stietenroth K, et al. Eflornithine is safer than melarsoprol for the treatment of second-stage Trypanosoma brucei gambiense human African trypanosomiasis. Clin Infect Dis. 2005 Sep 1;41(5):748-51. Resumo
148. Alirol E, Schrumpf D, Amici Heradi J, et al. Nifurtimox-eflornithine combination therapy for second-stage Gambiense human African trypanosomiasis: Médecins sans Frontières experience in the Democratic Republic of the Congo. Clin Infect Dis. 2013 Jan;56(2):195-203.Texto completo Resumo
149. Schmid C, Richer M, Bilenge CM, et al. Effectiveness of a 10-day melarsoprol schedule for the treatment of late-stage human African trypanosomiasis: confirmation from a multinational study (Impamel II). J Infect Dis. 2005 Jun 1;191(11):1922-31.Texto completo Resumo
150. Kuepfer I, Schmid C, Allan M, et al. Safety and efficacy of the 10-day melarsoprol schedule for the treatment of second stage Rhodesiense sleeping sickness. PLoS Negl Trop Dis. 2012 Aug;6(8):e1695.Texto completo Resumo
151. Eperon G, Schmid C, Loutan L, et al. Clinical presentation and treatment outcome of sleeping sickness in Sudanese pre-school children. Acta Trop. 2007 Jan;101(1):31-9. Resumo
152. Milord F, Pepin J, Loko L, et al. Efficacy and toxicity of eflornithine for treatment of Trypanosoma brucei gambiense sleeping sickness. Lancet. 1992 Sep 12;340(8820):652-5. Resumo
153. World Health Organization. WHO model prescribing information: drugs used in parasitic diseases, 2nd edition. Geneva: World Health Organization, 1995.Texto completo
154. Stauffert I, Paulini H, Steinmann U, et al. Investigations on mutagenicity and genotoxicity of pentamidine and some related trypanocidal diamidines. Mutation Research. 1990 Oct;245(2):93-8. Resumo
155. Freeman SJ, Lloyd JB. Evidence that suramin and aurothiomalate are teratogenic in rat by disturbing yolk sac-mediated embryonic protein nutrition. Chem Biol Interact. 1986 May;58(2):149-60. Resumo
156. Reinhardt MC, MacLeod CL. African trypanosomiasis (African sleeping sickness). In: MacLeod CL, ed. Parasitic infections in pregnancy and the newborn. Oxford: Oxford University Press; 1988:1-308.
157. Kirchner DL, Mercieca MD, Crowell JA, et al. Developmental toxicity studies of 2-(difluoromethyl)-dl-ornithine (DFMO) in rats and rabbits. Toxicol Sci. 1999 Jul;50(1):127-35.Texto completo Resumo
158. Mesu VKBK, Kalonji WM, Bardonneau C, et al. Oral fexinidazole for late-stage African Trypanosoma brucei gambiense trypanosomiasis: a pivotal multicentre, randomised, non-inferiority trial. Lancet. 2018 Jan 13;391(10116):144-154. Resumo
159. World Health Organization. Statement on the recent opinion of the European Medicines Agency on fexinidazole treatment for gambiense human African trypanosomiasis. November 2018 [internet publication].Texto completo
160. Rodgers J, Jones A, Gibaud S, et al. Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human African trypanosomiasis. PLoS Negl Trop Dis. 2011 Sep;5(9):e1308.Texto completo Resumo
161. Eperon G, Balasegaram M, Potet J, et al. Treatment options for second-stage gambiense human African trypanosomiasis. Expert Rev Anti Infect Ther. 2014 Nov;12(11):1407-17.Texto completo Resumo
162. Jacobs RT, Plattner JJ, Nare B, et al. Benzoxaboroles: a new class of potential drugs for human African trypanosomiasis. Future Med Chem. 2011 Aug;3(10):1259-78. Resumo
163. Jacobs RT, Nare B, Wring SA, et al. SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis. PLoS Negl Trop Dis. 2011 Jun;5(6):e1151.Texto completo Resumo
164. Robays J, Nyamowala G, Sese C, et al. High failure rates of melarsoprol for sleeping sickness, Democratic Republic of Congo. Emerg Infect Dis. 2008 Jun;14(6):966-7.Texto completo Resumo
165. Legros D, Evans S, Maiso F, et al. Risk factors for treatment failure after melarsoprol for Trypanosoma brucei gambiense trypanosomiasis in Uganda. Trans R Soc Trop Med Hyg. 1999 Jul-Aug;93(4):439-42. Resumo
166. World Health Organization. Epidemiology and control of African trypanosomiasis. WHO Technical Report Series 739. 1986 [internet publication].Texto completo
167. World Health Organization. Recommendations of the informal consultation on issues for clinical product development for human African trypanosomiasis. Geneva: WHO; 2007.Texto completo
168. Franco JR, Simarro PP, Diarra A, et al. Monitoring the use of nifurtimox-eflornithine combination therapy (NECT) in the treatment of second stage gambiense human African trypanosomiasis. Res Rep Trop Med. 2012;1:93-101.Texto completo
169. Fèvre EM, Coleman PG, Welburn SC, et al. Reanalyzing the 1900-1920 sleeping sickness epidemic in Uganda. Emerg Infect Dis. 2004 Apr;10(4):567-73.Texto completo Resumo
170. Fairlamb AH. Chemotherapy of human African trypanosomiasis: current and future prospects. Trends Parasitol. 2003 Nov;19(11):488-94. Resumo
171. Blum J, Nkunku S, Burri C. Clinical description of encephalopathic syndromes and risk factors for their occurrence and outcome during melarsoprol treatment of human African trypanosomiasis. Trop Med Int Health. 2001 May;6(5):390-400.Texto completo Resumo
172. Chappuis F. Eflornithine for the treatment of human African trypanosomiasis; practical perspectives [in French]. Développement et Santé. 2004;171:41-47.
173. Priotto G, Chappuis F, Bastard M, et al. Early prediction of treatment efficacy in second-stage gambiense human African trypanosomiasis. PLoS Negl Trop Dis.2012;6(6):e1662.Texto completo Resumo
174. Mumba Ngoyi D, Lejon V, Pyana P, et al. How to shorten patient follow-up after treatment for Trypanosoma brucei gambiense sleeping sickness. J Infect Dis. 2010 Feb 1;201(3):453-63. Resumo
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