Deficiências do complemento

Referências

Principais artigos

Schröder-Braunstein J, Kirschfink M. Complement deficiencies and dysregulation: pathophysiological consequences, modern analysis, and clinical management. Mol Immunol. 2019 Oct;114:299-311. Resumo

Grumach AS, Kirschfink M. Are complement deficiencies really rare? Overview on prevalence, clinical importance and modern diagnostic approach. Mol Immunol. 2014 Oct;61(2):110-7. Resumo

Maurer M, Magerl M, Betschel S, et al. The international WAO/EAACI guideline for the management of hereditary angioedema-The 2021 revision and update. Allergy. 2022 Jul;77(7):1961-90.Texto completo  Resumo

Brodszki N, Frazer-Abel A, Grumach AS, et al. European Society for Immunodeficiencies (ESID) and European Reference Network on Rare Primary Immunodeficiency, Autoinflammatory and Autoimmune Diseases (ERN RITA) complement guideline: deficiencies, diagnosis, and management. J Clin Immunol. 2020 May;40(4):576-91.Texto completo  Resumo

Artigos de referência

1. Merle NS, Church SE, Fremeaux-Bacchi V, et al. Complement system part I - molecular mechanisms of activation and regulation. Front Immunol. 2015 Jun 2;6:262.Texto completo  Resumo

2. Merle NS, Noe R, Halbwachs-Mecarelli L, et al. Complement system part II: role in immunity. Front Immunol. 2015 May 26;6:257.Texto completo  Resumo

3. Hajishengallis G, Reis ES, Mastellos DC, et al. Novel mechanisms and functions of complement. Nat Immunol. 2017 Nov 16;18(12):1288-8. Resumo

4. Reis ES, Mastellos DC, Hajishengallis G, et al. New insights into the immune functions of complement. Nat Rev Immunol. 2019 Aug;19(8):503-16.Texto completo  Resumo

5. Ekdahl KN, Teramura Y, Hamad OA, et al. Dangerous liaisons: complement, coagulation, and kallikrein/kinin cross-talk act as a linchpin in the events leading to thromboinflammation. Immunol Rev. 2016 Nov;274(1):245-69. Resumo

6. Ricklin D, Lambris JD. Complement in immune and inflammatory disorders: pathophysiological mechanisms. J Immunol. 2013 Apr 15;190(8):3831-8.Texto completo  Resumo

7. Kojima T, Inoue D, Wajima T, et al. Circulating immune-complexes and complement activation through the classical pathway in myeloperoxidase-ANCA-associated glomerulonephritis. Ren Fail. 2022 Dec;44(1):714-23.Texto completo  Resumo

8. van der Ende EL, Heller C, Sogorb-Esteve A, et al. Elevated CSF and plasma complement proteins in genetic frontotemporal dementia: results from the GENFI study. J Neuroinflammation. 2022 Sep 5;19(1):217.Texto completo  Resumo

9. Koski CL, Sanders ME, Swoveland PT, et al. Activation of terminal components of complement in patients with Guillain-Barré syndrome and other demyelinating neuropathies. J Clin Invest. 1987 Nov;80(5):1492-7.Texto completo  Resumo

10. Saez-Calveras N, Stuve O. The role of the complement system in multiple sclerosis: a review. Front Immunol. 2022 Aug 10;13:970486.Texto completo  Resumo

11. Ekdahl KN, Huang S, Nilsson B, et al. Complement inhibition in biomaterial- and biosurface-induced thromboinflammation. Semin Immunol. 2016 Jun;28(3):268-77.Texto completo  Resumo

12. Pettigrew HD, Teuber SS, Gershwin ME. Clinical significance of complement deficiencies. Ann N Y Acad Sci. 2009 Sep;1173:108-23. Resumo

13. Degn SE, Jensenius JC, Thiel S. Disease-causing mutations in genes of the complement system. Am J Hum Genet. 2011 Jun 10;88(6):689-705.Texto completo  Resumo

14. Skattum L, Van deuren M, Van der poll T, et al. Complement deficiency states and associated infections. Mol Immunol. 2011 Aug;48(14):1643-55. Resumo

15. Figueroa JE, Densen P. Infectious diseases associated with complement deficiencies. Clin Microbiol Rev. 1991 Jul;4(3):359-95.Texto completo  Resumo

16. Schröder-Braunstein J, Kirschfink M. Complement deficiencies and dysregulation: pathophysiological consequences, modern analysis, and clinical management. Mol Immunol. 2019 Oct;114:299-311. Resumo

17. Lhotta K, Janecke AR, Scheiring J, et al. A large family with a gain-of-function mutation of complement C3 predisposing to atypical hemolytic uremic syndrome, microhematuria, hypertension and chronic renal failure. Clin J Am Soc Nephrol. 2009 Aug;4(8):1356-62.Texto completo  Resumo

18. Urban A, Volokhina E, Felberg A, et al. Gain-of-function mutation in complement C2 protein identified in a patient with aHUS. J Allergy Clin Immunol. 2020 Oct;146(4):916-9.e11.Texto completo  Resumo

19. Arbore G, Kemper C, Kolev M. Intracellular complement - the complosome - in immune cell regulation. Mol Immunol. 2017 Sep;89:2-9.Texto completo  Resumo

20. Mayilyan KR. Complement genetics, deficiencies, and disease associations. Protein Cell. 2012 Jul;3(7):487-96.Texto completo  Resumo

21. Noris M, Remuzzi G. Overview of complement activation and regulation. Semin Nephrol. 2013 Nov;33(6):479-92.Texto completo  Resumo

22. Grumach AS, Kirschfink M. Are complement deficiencies really rare? Overview on prevalence, clinical importance and modern diagnostic approach. Mol Immunol. 2014 Oct;61(2):110-7. Resumo

23. Gompels MM, Lock RJ, Albinun M, et al. C1 inhibitor deficiency: consensus document. Clin Exp Immunol. 2005 Mar;139(3):379-94.Texto completo  Resumo

24. Maurer M, Magerl M, Betschel S, et al. The international WAO/EAACI guideline for the management of hereditary angioedema-The 2021 revision and update. Allergy. 2022 Jul;77(7):1961-90.Texto completo  Resumo

25. Walport MJ. Complement: first of two parts. N Engl J Med. 2001 Apr 5;344(14):1058-66. Resumo

26. Walport MJ. Complement: second of two parts. N Engl J Med. 2001 Apr 12;344(15):1140-4. Resumo

27. Unsworth DJ. Complement deficiency and disease. J Clin Pathol. 2008 Sep;61(9):1013-7. Resumo

28. Ellison RT 3rd, Kohler PF, Curd JG, et al. Prevalence of congenital or acquired complement deficiency in patients with sporadic meningococcal disease. N Engl J Med. 1983 Apr 21;308(16):913-6. Resumo

29. Leggiadro RJ, Winkelstein JA. Prevalence of complement deficiencies in children with systemic meningococcal infections. Pediatr Infect Dis J. 1987 Jan;6(1):75-6.Texto completo  Resumo

30. Quillin SJ, Seifert HS. Neisseria gonorrhoeae host adaptation and pathogenesis. Nat Rev Microbiol. 2018 Apr;16(4):226-40.Texto completo  Resumo

31. Tangye SG, Al-Herz W, Bousfiha A, et al. Human inborn errors of immunity: 2019 update on the classification from the International Union of Immunological Societies Expert Committee. J Clin Immunol. 2020 Jan;40(1):24-64.Texto completo  Resumo

32. Levy JH, Freiberger DJ, Roback J. Hereditary angioedema: current and emerging treatment options. Anesth Analg. 2010 May 1;110(5):1271-80.Texto completo  Resumo

33. Caccia S, Suffritti C, Cicardi M. Pathophysiology of hereditary angioedema. Pediatr Allergy Immunol Pulmonol. 2014 Dec 1;27(4):159-63.Texto completo  Resumo

34. Zuraw BL, Bernstein JA, Lang DM, et al. A focused parameter update: hereditary angioedema, acquired C1 inhibitor deficiency, and angiotensin-converting enzyme inhibitor-associated angioedema. J Allergy Clin Immunol. 2013 Jun;131(6):1491-3.Texto completo  Resumo

35. Breitbart SI, Bielory L, Breitbart SI, et al. Acquired angioedema: Autoantibody associations and C1q utility as a diagnostic tool. Allergy Asthma Proc. 2010 Sep-Oct;31(5):428-34. Resumo

36. Bork K, Staubach-Renz P, Hardt J. Angioedema due to acquired C1-inhibitor deficiency: spectrum and treatment with C1-inhibitor concentrate. Orphanet J Rare Dis. 2019 Mar 13;14(1):65.Texto completo  Resumo

37. Bork K, Gül D, Hardt J, et al. Hereditary angioedema with normal C1 inhibitor: clinical symptoms and course. Am J Med. 2007 Nov;120(11):987-92. Resumo

38. Veronez CL, Csuka D, Sheikh FR, et al. The expanding spectrum of mutations in hereditary angioedema. J Allergy Clin Immunol Pract. 2021 Jun;9(6):2229-34. Resumo

39. Brodszki N, Frazer-Abel A, Grumach AS, et al. European Society for Immunodeficiencies (ESID) and European Reference Network on Rare Primary Immunodeficiency, Autoinflammatory and Autoimmune Diseases (ERN RITA) complement guideline: deficiencies, diagnosis, and management. J Clin Immunol. 2020 May;40(4):576-91.Texto completo  Resumo

40. Macedo AC, Isaac L. Systemic lupus erythematosus and deficiencies of early components of the complement classical pathway. Front Immunol. 2016 Feb 24;7:55.Texto completo  Resumo

41. Trendelenburg M. Autoantibodies against complement component C1q in systemic lupus erythematosus. Clin Transl Immunology. 2021 Apr 29;10(4):e1279.Texto completo  Resumo

42. Carroll MC. A protective role for innate immunity in systemic lupus erythematosus. Nat Rev Immunol. 2004 Oct;4(10):825-31. Resumo

43. Weinstein A, Alexander RV, Zack DJ. A review of complement activation in SLE. Curr Rheumatol Rep. 2021 Feb 10;23(3):16.Texto completo  Resumo

44. Lewis LA, Ram S. Meningococcal disease and the complement system. Virulence. 2014 Jan 1;5(1):98-126.Texto completo  Resumo

45. UK Health Security Agency. The complete routine immunisation schedule from February 2022. Feb 2022 [internet publication].Texto completo

46. Centers for Disease Control and Prevention. Child and adolescent immunization schedule by age: recommendations for ages 18 years or younger, United States, 2024. Nov 2023 [internet publication].Texto completo

47. Centers for Disease Control and Prevention. Adult immunization schedule by age: recommendations for ages 19 years or older, United States, 2024. Nov 2023 [internet publication].Texto completo

48. Cook HT. Complement and kidney disease. Curr Opin Nephrol Hypertens. 2013 May;22(3):295-301. Resumo

49. Noris M, Remuzzi G. Genetics of immune-mediated glomerular diseases: focus on complement. Semin Nephrol. 2017 Sep;37(5):447-63. Resumo

50. Willows J, Brown M, Sheerin NS. The role of complement in kidney disease. Clin Med (Lond). 2020 Mar;20(2):156-60.Texto completo  Resumo

51. Smith RJH, Appel GB, Blom AM, et al. C3 glomerulopathy - understanding a rare complement-driven renal disease. Nat Rev Nephrol. 2019 Mar;15(3):129-43.Texto completo  Resumo

52. Cook HT. C3 glomerulopathy. F1000Res. 2017 Mar 10;6:248.Texto completo  Resumo

53. Corvillo F, Okrój M, Nozal P, et al. Nephritic factors: an overview of classification, diagnostic tools and clinical associations. Front Immunol. 2019 Apr 24;10:886.Texto completo  Resumo

54. Jokiranta TS. HUS and atypical HUS. Blood. 2017 May 25;129(21):2847-56.Texto completo  Resumo

55. Fritsche LG, Igl W, Bailey JN, et al. A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants. Nat Genet. 2016 Feb;48(2):134-43.Texto completo  Resumo

56. Hill A, DeZern AE, Kinoshita T, et al. Paroxysmal nocturnal haemoglobinuria. Nat Rev Dis Primers. 2017 May 18;3:17028. Resumo

57. Gorevic PD. Rheumatoid factor, complement, and mixed cryoglobulinemia. Clin Dev Immunol. 2012;2012:439018.Texto completo  Resumo

58. Levy Y, George J, Yona E, et al. Partial lipodystrophy, mesangiocapillary glomerulonephritis, and complement dysregulation. An autoimmune phenomenon. Immunol Res. 1998 Aug;18(1):55-60. Resumo

59. Prohászka Z, Nilsson B, Frazer-Abel A, et al. Complement analysis 2016: clinical indications, laboratory diagnostics and quality control. Immunobiology. 2016 Nov;221(11):1247-58. Resumo

60. Ling M, Murali M. Analysis of the complement system in the clinical immunology laboratory. Clin Lab Med. 2019 Dec;39(4):579-90. Resumo

61. Frazer-Abel A, Kirschfink M, Prohászka Z. Expanding horizons in complement analysis and quality control. Front Immunol. 2021 Aug 9;12:697313.Texto completo  Resumo

62. Seelen MA, Roos A, Wieslander J, et al. Functional analysis of the classical, alternative, and MBL pathways of the complement system: standardization and validation of a simple ELISA. J Immunol Methods. 2005 Jan;296(1-2):187-98. Resumo

63. Wehling C, Amon O, Bommer M, et al. Monitoring of complement activation biomarkers and eculizumab in complement-mediated renal disorders. Clin Exp Immunol. 2017 Feb;187(2):304-15.Texto completo  Resumo

64. Fakhouri F, Frémeaux-Bacchi V. Thrombotic microangiopathy in aHUS and beyond: clinical clues from complement genetics. Nat Rev Nephrol. 2021 Aug;17(8):543-53. Resumo

65. Germenis AE, Margaglione M, Pesquero JB, et al. International consensus on the use of genetics in the management of hereditary angioedema. J Allergy Clin Immunol Pract. 2020 Mar;8(3):901-11. Resumo

66. Licht C, Weyersburg A, Heinen S, et al. Successful plasma therapy for atypical hemolytic uremic syndrome caused by factor H deficiency owing to a novel mutation in the complement cofactor protein domain 15. Am J Kidney Dis. 2005 Feb;45(2):415-21. Resumo

67. Ricklin D, Mastellos DC, Reis ES, et al. The renaissance of complement therapeutics. Nat Rev Nephrol. 2018 Jan;14(1):26-47.Texto completo  Resumo

68. Fakhouri F, Frémeaux-Bacchi V, Loirat C. Atypical hemolytic uremic syndrome: from the rediscovery of complement to targeted therapy. Eur J Intern Med. 2013 Sep;24(6):492-5. Resumo

69. Mastellos DC, Ricklin D, Lambris JD. Clinical promise of next-generation complement therapeutics. Nat Rev Drug Discov. 2019 Sep;18(9):707-29.Texto completo  Resumo

70. Caballero T. Treatment of hereditary angioedema. J Investig Allergol Clin Immunol. 2021 Feb;31(1):1-16.Texto completo  Resumo

71. Centers for Disease Control and Prevention. Vaccine recommendations and guidelines of the ACIP. General best practice guidelines for immunization: altered immunocompetence. Aug 2023 [internet publication].Texto completo

72. Caballero T, Farkas H, Bouillet L, et al. International consensus and practical guidelines on the gynecologic and obstetric management of female patients with hereditary angioedema caused by C1 inhibitor deficiency. J Allergy Clin Immunol. 2012 Feb;129(2):308-20.Texto completo  Resumo

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