Eczema

Referências

Principais artigos

Sidbury R, Tom WL, Bergman JN, et al. Guidelines of care for the management of atopic dermatitis: section 4. Prevention of disease flares and use of adjunctive therapies and approaches. J Am Acad Dermatol. 2014 Dec;71(6):1218-33.Texto completo  Resumo

Eichenfield LF, Tom WL, Chamlin SL, et al. Guidelines of care for the management of atopic dermatitis: section 1. Diagnosis and assessment of atopic dermatitis. J Am Acad Dermatol. 2014 Feb;70(2):338-51.Texto completo  Resumo

van Zuuren EJ, Fedorowicz Z, Christensen R, et al. Emollients and moisturisers for eczema. Cochrane Database Syst Rev. 2017 Feb 6;(2):CD012119.Texto completo  Resumo

Sidbury R, Davis DM, Cohen DE, et al; American Academy of Dermatology. Guidelines of care for the management of atopic dermatitis: section 3. Management and treatment with phototherapy and systemic agents. J Am Acad Dermatol. 2014 Aug;71(2):327-49.Texto completo  Resumo

Eichenfield LF, Tom WL, Berger TG, et al. Guidelines of care for the management of atopic dermatitis: section 2. Management and treatment of atopic dermatitis with topical therapies. J Am Acad Dermatol. 2014 Jul;71(1):116-32.Texto completo  Resumo

Artigos de referência

1. Spergel JM, Paller AS. Atopic dermatitis and the atopic march. J Allergy Clin Immunol. 2003 Dec;112(6 Suppl):S118-27. Resumo

2. Kim JP, Chao LX, Simpson EL, et al. Persistence of atopic dermatitis (AD): a systematic review and meta-analysis. J Am Acad Dermatol. 2016 Oct;75(4):681-87;e11.Texto completo  Resumo

3. Chopra R, Vakharia PP, Sacotte R, et al. Severity strata for Eczema Area and Severity Index (EASI), modified EASI, Scoring Atopic Dermatitis (SCORAD), objective SCORAD, Atopic Dermatitis Severity Index and body surface area in adolescents and adults with atopic dermatitis. Br J Dermatol. 2017 Nov;177(5):1316-21. Resumo

4. National Institute for Health and Care Excellence. Dupilumab for treating moderate to severe atopic dermatitis. August 2018 [internet publication].Texto completo

5. Agache I, Akdis CA, Akdis M, et al. EAACI biologicals guidelines: dupilumab for children and adults with moderate-to-severe atopic dermatitis. Allergy. 2021 Apr;76(4):988-1009. Resumo

6. Williams H. Atopic Dermatitis. N Engl J Med. 2005 Jun 2;352(22):2314-24. Resumo

7. Paller AS, Mancini J. Hurwitz clinical pediatric dermatology: a textbook of skin disorders of childhood and adolescence. 5th ed. Philadelphia, PA: Elsevier Saunders; 2016.

8. Hirano SA, Murray SB, Harvey VM. Reporting, representation, and subgroup analysis of race and ethnicity in published clinical trials of atopic dermatitis in the United States between 2000 and 2009. Pediatr Dermatol. 2012 Nov-Dec;29(6):749-55. Resumo

9. Leung D, Boguniewicz M, Howell MD, et al. New insights into atopic dermatitis. The J Clin Invest. 2004 Mar;113(5):651-7.Texto completo  Resumo

10. Chiesa Fuxench ZC, Block JK, Boguniewicz M, et al. Atopic dermatitis in America study: a cross-sectional study examining the prevalence and disease burden of atopic dermatitis in the US adult population. J Invest Dermatol. 2019 Mar;139(3):583-90.Texto completo  Resumo

11. Silverberg JI, Gelfand JM, Margolis DJ, et al. Patient burden and quality of life in atopic dermatitis in US adults: a population-based cross-sectional study. Ann Allergy Asthma Immunol. 2018 Sep;121(3):340-7.Texto completo  Resumo

12. Bylund S, von Kobyletzki LB, Svalstedt M, et al. Prevalence and incidence of atopic dermatitis: a systematic review. Acta Derm Venereol. 2020 Jun 9;100(12):adv00160.Texto completo  Resumo

13. Flohr C, Yeo L. Atopic dermatitis and the hygiene hypothesis revisited. Curr Probl Dermatol. 2011;41:1-34. Resumo

14. Morar N, Cookson W, Harper JI, et al. Filaggrin Mutations in Children with Severe Atopic Dermatitis. J Invest Dermatol. 2007 Jul;127(7):1667-72.Texto completo  Resumo

15. Palmer CN, Irvine AD, Terron-Kwiatkowski A, et al. Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis. Nat Genet. 2006 Apr;38(4):441-6. Resumo

16. Meagher LJ, Wines NY, Cooper AJ. Atopic dermatitis: review of immunopathogenesis and advances in immunosuppressive therapy. Australas J Dermatol. 2002 Nov;43(4):247-54. Resumo

17. McLean WH. Filaggrin failure: from ichthyosis vulgaris to atopic eczema and beyond. Br J Dermatol. 2016 Oct;175 Suppl 2(Suppl 2):4-7.Texto completo  Resumo

18. McGrath JA. Filaggrin and the great epidermal barrier grief. Australas J Dermatol. 2008 May;49(2):67-73; quiz 73-4. Resumo

19. Kantor R, Silverberg JI. Environmental risk factors and their role in the management of atopic dermatitis. Expert Rev Clin Immunol. 2017 Jan;13(1):15-26.Texto completo  Resumo

20. Tamagawa-Mineoka R, Katoh N. Atopic dermatitis: identification and management of complicating factors. Int J Mol Sci. 2020 Apr 11;21(8):2671.Texto completo  Resumo

21. Geoghegan JA, Irvine AD, Foster TJ. Staphylococcus aureus and atopic dermatitis: a complex and evolving relationship. Trends Microbiol. 2018 Jun;26(6):484-97. Resumo

22. Howell MD, Kim BE, Gao P, et al. Cytokine modulation of atopic dermatitis filaggrin skin expression. J Allergy Clin Immunol. 2007 Jul;120(1):150-5. Resumo

23. Løset M, Brown SJ, Saunes M, et al. Genetics of atopic dermatitis: from DNA sequence to clinical relevance. Dermatology. 2019;235(5):355-64.Texto completo  Resumo

24. Carlsten C, Dimich-Ward H, Ferguson A, et al. Atopic dermatitis in a high-risk cohort: natural history, associated allergic outcomes, and risk factors. Ann Allergy Asthma Immunol. 2013 Jan;110(1):24-8. Resumo

25. Schultz Larsen F, Diepgen T, Svensson A. The occurrence of atopic dermatitis in north Europe: an international questionnaire study. J Am Acad Dermatol. 1996 May;34(5 pt 1):760-4. Resumo

26. Kantor R, Kim A, Thyssen JP, et al. Association of atopic dermatitis with smoking: a systematic review and meta-analysis. J Am Acad Dermatol. 2016 Dec;75(6):1119-25;e1.Texto completo  Resumo

27. Kramer MS, Kakuma R. Maternal dietary antigen avoidance during pregnancy or lactation, or both, for preventing or treating atopic disease in the child. Cochrane Database Syst Rev. 2012 Sep 12;(9):CD000133.Texto completo  Resumo

28. Kramer MS, Kakuma R. Maternal dietary antigen avoidance during pregnancy or lactation, or both, for preventing or treating atopic disease in the child. Evid Based Child Health. 2014 Jun;9(2):447-83. Resumo

29. Cuello-Garcia CA, Brożek JL, Fiocchi A, et al. Probiotics for the prevention of allergy: a systematic review and meta-analysis of randomized controlled trials. J Allergy Clin Immunol. 2015 Oct;136(4):952-61. Resumo

30. Makrgeorgou A, Leonardi-Bee J, Bath-Hextall FJ, et al. Probiotics for treating eczema. Cochrane Database Syst Rev. 2018 Nov 21;(11):CD006135.Texto completo  Resumo

31. Tan-Lim CSC, Esteban-Ipac NAR, Recto MST, et al. Comparative effectiveness of probiotic strains on the prevention of pediatric atopic dermatitis: a systematic review and network meta-analysis. Pediatr Allergy Immunol. 2021 Aug;32(6):1255-70. Resumo

32. Kelleher MM, Cro S, Cornelius V, et al. Skin care interventions in infants for preventing eczema and food allergy. Cochrane Database Syst Rev. 2021 Feb 5;2(2):CD013534.Texto completo  Resumo

33. Sidbury R, Tom WL, Bergman JN, et al. Guidelines of care for the management of atopic dermatitis: section 4. Prevention of disease flares and use of adjunctive therapies and approaches. J Am Acad Dermatol. 2014 Dec;71(6):1218-33.Texto completo  Resumo

34. Eichenfield LF, Tom WL, Chamlin SL, et al. Guidelines of care for the management of atopic dermatitis: section 1. Diagnosis and assessment of atopic dermatitis. J Am Acad Dermatol. 2014 Feb;70(2):338-51.Texto completo  Resumo

35. Eigenmann PA, Sicherer SH, Borkowski TA, et al. Prevalence of IgE-mediated food allergy among children with atopic dermatitis. Pediatrics. 1998 Mar;101(3):E8.Texto completo  Resumo

36. Wollenberg A, Barbarot S, Bieber T, et al. Consensus-based European guidelines for treatment of atopic eczema (atopic dermatitis) in adults and children: part I. J Eur Acad Dermatol Venereol. 2018 May;32(5):657-82.Texto completo  Resumo

37. Beattie PE, Green C, Lowe G, et al. Which children should we patch test? Clin Exp Dermatol. 2007 Jan;32(1):6-11. Resumo

38. Milingou M, Tagka A, Armenaka M, et al. Patch tests in children: a review of 13 years of experience in comparison with previous data. Pediatr Dermatol. 2010 May-Jun;27(3):255-9. Resumo

39. Pigatto P, Martelli A, Marsili C, et al. Contact dermatitis in children. Ital J Pediatr. 2010 Jan 13;36:2.Texto completo  Resumo

40. Owen JL, Vakharia PP, Silverberg JI. The role and diagnosis of allergic contact dermatitis in patients with atopic dermatitis. Am J Clin Dermatol. 2018 Jun;19(3):293-302.Texto completo  Resumo

41. Jacob SE, Burk CJ, Connelly EA. Patch testing: another steroid-sparing agent to consider in children. Pediatr Dermatol. 2008 Jan-Feb;25(1):81-7. Resumo

42. Barnetson R, Rogers M. Childhood atopic eczema. BMJ. 2002 Jun 8;324(7350):1376-9. Resumo

43. Piloto Valdés L, Gómez Echevarría AH, Valdés Sánchez AF, et al. Atopic dermatitis: findings of skin biopsies. Allergol Immunopathol (Madr). 1990 Nov-Dec;18(6):321-4. Resumo

44. Weinstock MA, Horm JW. Mycosis fungoides in the United States. Increasing incidence and descriptive epidemiology. JAMA. 1988 Jul 1;260(1):42-6. Resumo

45. Hanifin JM, Rajka G. Diagnostic features of atopic dermatitis. Acta Dermatol Vereneol. 1980;92(suppl):44-47.

46. De D, Kanwar AJ, Handa S. Comparative efficacy of Hanifin and Rajka's criteria and the UK working party's diagnostic criteria in diagnosis of atopic dermatitis in a hospital setting in North India. JEADV. 2006 Aug;20(7):853-9. Resumo

47. Vakharia PP, Chopra R, Silverberg JI. Systematic review of diagnostic criteria used in atopic dermatitis randomized controlled trials. Am J Clin Dermatol. 2018 Feb;19(1):15-22. Resumo

48. Johnke H, Vach W, Norberg LA, et al. A comparison between criteria for diagnosing atopic eczema in infants. Br J Dermatol. 2005 Aug;153(2):352-8. Resumo

49. Williams HC, Burney PG, Pembroke AC, et al. Validation of the U.K. diagnostic criteria for atopic dermatitis in a population setting. Br J Dermatol. 1996 Jul;135(1):12-7. Resumo

50. Williams HC, Burney PG, Hay RJ, et al. The U.K. Working Party's Diagnostic Criteria for Atopic Dermatitis. I. Derivation of a minimum set of discriminators for atopic dermatitis. Br J Dermatol. 1994 Sep;131(3):383-96. Resumo

51. Fleming S, Bodner C, Devereux G, et al. An application of the United Kingdom Working Party diagnostic criteria for atopic dermatitis in Scottish infants. J Invest Dermatol. 2001 Dec;117(6):1526-30. Resumo

52. Levy ML. Atopic dermatitis: understanding the disease and its management. Curr Med Res Opin. 2007 Dec;23(12):3091-103. Resumo

53. Darsow U, Wollenberg A, Simon D, et al. ETFAD/EADV eczema task force 2009 position paper on diagnosis and treatment of atopic dermatitis. J Eur Acad Dermatol Venereol. 2010 Mar;24(3):317-28.Texto completo  Resumo

54. Simpson EL. Atopic dermatitis: a review of topical treatment options. Cur Med Res Opin. 2010 Mar;26(3):633-40. Resumo

55. Kosse RC, Bouvy ML, Daanen M, et al. Adolescents' perspectives on atopic dermatitis treatment-experiences, preferences, and beliefs. JAMA Dermatol. 2018 Jul 1;154(7):824-7.Texto completo  Resumo

56. van Zuuren EJ, Fedorowicz Z, Christensen R, et al. Emollients and moisturisers for eczema. Cochrane Database Syst Rev. 2017 Feb 6;(2):CD012119.Texto completo  Resumo

57. Sidbury R, Davis DM, Cohen DE, et al; American Academy of Dermatology. Guidelines of care for the management of atopic dermatitis: section 3. Management and treatment with phototherapy and systemic agents. J Am Acad Dermatol. 2014 Aug;71(2):327-49.Texto completo  Resumo

58. Yu SH, Drucker AM, Lebwohl M, et al. A systematic review of the safety and efficacy of systemic corticosteroids in atopic dermatitis. J Am Acad Dermatol. 2018 Apr;78(4):733-40. Resumo

59. Eckert L, Gupta S, Amand C, et al. Impact of atopic dermatitis on health-related quality of life and productivity in adults in the United States: an analysis using the National Health and Wellness Survey. J Am Acad Dermatol. 2017 Aug;77(2):274-9.Texto completo  Resumo

60. Teasdale E, Muller I, Sivyer K, et al. Views and experiences of managing eczema: systematic review and thematic synthesis of qualitative studies. Br J Dermatol. 2021 Apr;184(4):627-37.Texto completo  Resumo

61. Eichenfield LF, Tom WL, Berger TG, et al. Guidelines of care for the management of atopic dermatitis: section 2. Management and treatment of atopic dermatitis with topical therapies. J Am Acad Dermatol. 2014 Jul;71(1):116-32.Texto completo  Resumo

62. Czarnowicki T, Malajian D, Khattri S, et al. Petrolatum: barrier repair and antimicrobial responses underlying this "inert" moisturizer. J Allergy Clin Immunol. 2016 Apr;137(4):1091-102.Texto completo  Resumo

63. Nicol NH, Boguniewicz M, Strand M, et al. Wet wrap therapy in children with moderate to severe atopic dermatitis in a multidisciplinary treatment program. J Allergy Clin Immunol Pract. Jul-Aug 2014;2(4):400-6. Resumo

64. Del Rosso JQ, Bhambri S. Daily application of fluocinonide 0.1% cream for the treatment of atopic dermatitis. J Clin Aesthet Dermatol. 2009 Sep;2(9):24-32.Texto completo  Resumo

65. El Hachem M, Gesualdo F, Ricci G, et al. Topical corticosteroid phobia in parents of pediatric patients with atopic dermatitis: a multicentre survey. Ital J Pediatr. 2017 Feb 28;43(1):22.Texto completo  Resumo

66. Smith SD, Hong E, Fearns S, et al. Corticosteroid phobia and other confounders in the treatment of childhood atopic dermatitis explored using parent focus groups. Australas J Dermatol. 2010 Aug;51(3):168-74. Resumo

67. Veenje S, Osinga H, Antonescu I, et al. Focus group parental opinions regarding treatment with topical corticosteroids on children with atopic dermatitis. Allergol Immunopathol (Madr). Mar-Apr 2019;47(2):166-71.Texto completo  Resumo

68. Matheson R, Kempers S, Breneman D, et al. Hydrocortisone butyrate 0.1% lotion in the treatment of atopic dermatitis in pediatric subjects. J Drugs Dermatol. 2008 Mar;7(3):266-71. Resumo

69. Wolverton SE. Comprehensive dermatologic drug therapy. 2nd ed. Philadelphia, PA: Elsevier Saunders; 2007.

70. Callen J, Chamlin S, Eichenfield LF, et al. A systematic review of the safety of topical therapies for atopic dermatitis. Br J Dermatol. 2007 Feb;156(2):203-21. Resumo

71. Jeziorkowska R, Sysa-Jędrzejowska A, Samochocki Z. Topical steroid therapy in atopic dermatitis in theory and practice. Postepy Dermatol Alergol. 2015 Jun 10;32(3):162-6. Resumo

72. Trookman NS, Rizer RL. Randomized controlled trial of desonlde hydrogel 0.05% versus desonide ointment 0.05% in the treatment of mild-to-moderate atopic dermatitis. J Clin Aesthet Dermatol. 2011 Nov;4(11):34-8.Texto completo  Resumo

73. Sher LG, Chang J, Patel IB, et al. Relieving the pruritus of atopic dermatitis: a meta-analysis. Acta Derm Venereol. 2012 Sep;92(5):455-61. Resumo

74. Cury Martins J, Martins C, Aoki V, et al. Topical tacrolimus for atopic dermatitis. Cochrane Database Syst Rev. 2015 Jul 1;(7):CD009864.Texto completo  Resumo

75. Paller AS, Fölster-Holst R, Chen SC, et al. No evidence of increased cancer incidence in children using topical tacrolimus for atopic dermatitis. J Am Acad Dermatol. 2020 Aug;83(2):375-81.Texto completo  Resumo

76. Beck LA, Thaçi D, Hamilton JD, et al. Dupilumab treatment in adults with moderate-to-severe atopic dermatitis. N Engl J Med. 2014 Jul 10;371(2):130-9.Texto completo  Resumo

77. Yang H, Wang J, Zhang X, et al. Application of topical phosphodiesterase 4 inhibitors in mild to moderate atopic dermatitis: a systematic review and meta-analysis. JAMA Dermatol. 2019 May 1;155(5):585-93.Texto completo  Resumo

78. Draelos ZD, Stein Gold LF, Murrell DF, et al. Post hoc analyses of the effect of crisaborole topical ointment, 2% on atopic dermatitis: associated pruritus from phase 1 and 2 clinical studies. J Drugs Dermatol. 2016 Feb;15(2):172-6. Resumo

79. Gong JQ, Lin L, Lin T, et al. Skin colonization by Staphylococcus aureus in patients with eczema and atopic dermatitis and relevant combined topical therapy: a double-blind multicentre randomized controlled trial. Br J Dermatol. 2006 Oct;155(4):680-7. Resumo

80. Dickman M, Dawson AL, Dellavalle RP. The relationship between hygiene and microbial burden in atopic dermatitis risk based on a systematic review. Arch Dermatol. 2012 Aug;148(8):936-8. Resumo

81. Anderson PC, Dinulos JG. Atopic dermatitis and alternative management strategies. Curr Opin Pediatr. 2009 Feb;21(1):131-8. Resumo

82. Huang JT, Rademaker A, Paller AS. Dilute bleach baths for Staphylococcus aureus colonization in atopic dermatitis to decrease disease severity. Arch Dermatol. 2011 Feb;147(2):246-7. Resumo

83. British Association of Dermatologists. Service guidance and standards for phototherapy units. October 2016 [internet publication].Texto completo

84. Elsner P, Agner T. Hand eczema: treatment. J Eur Acad Dermatol Venereol. 2020 Jan;34 Suppl 1:13-21.Texto completo  Resumo

85. Simpson EL, Bruin-Weller M, Flohr C, et al. When does atopic dermatitis warrant systemic therapy? Recommendations from an expert panel of the International Eczema Council. J Am Acad Dermatol. 2017 Oct;77(4):623-33.Texto completo  Resumo

86. Agache I, Song Y, Posso M, et al. Efficacy and safety of dupilumab for moderate-to-severe atopic dermatitis: a systematic review for the EAACI biologicals guidelines. Allergy. 2021 Jan;76(1):45-58.Texto completo  Resumo

87. Schmitt J, Schäkel K, Schmitt N, et al. Systemic treatment of severe atopic eczema: a systematic review. Acta Derm Venereol. 2007;87(2):100-11. Resumo

88. Gooderham M, Lynde CW, Papp K, et al. Review of systemic treatment options for adult atopic dermatitis. J Cutan Med Surg. 2017 Jan/Feb;21(1):31-9. Resumo

89. Siegels D, Heratizadeh A, Abraham S, et al. Systemic treatments in the management of atopic dermatitis: a systematic review and meta-analysis. Allergy. 2021 Apr;76(4):1053-76. Resumo

90. Taylor K, Swan DJ, Affleck A, et al. Treatment of moderate-to-severe atopic eczema in adults within the U.K.: results of a national survey of dermatologists. Br J Dermatol. 2017 Jun;176(6):1617-23.Texto completo  Resumo

91. Drucker AM, Ellis AG, Bohdanowicz M, et al. Systemic immunomodulatory treatments for patients with atopic dermatitis: a systematic review and network meta-analysis. JAMA Dermatol. 2020 Jun 1;156(6):659-67.Texto completo  Resumo

92. Schmitt J, Schmitt N, Meurer M. Cyclosporin in the treatment of patients with atopic eczema: a systematic review and meta-analysis. J Eur Acad Dermatol Venereol. 2007 May;21(5):606-19. Resumo

93. Roekevisch E, Spuls PI, Kuester D, et al. Efficacy and safety of systemic treatments for moderate-to-severe atopic dermatitis: a systematic review. J Allergy Clin Immunol. 2014 Feb;133(2):429-38. Resumo

94. Gerbens LAA, Hamann SAS, Brouwer MWD, et al. Methotrexate and azathioprine for severe atopic dermatitis: a 5-year follow-up study of a randomized controlled trial. Br J Dermatol. 2018 Jun;178(6):1288-96. Resumo

95. Schram ME, Roekevisch E, Leeflang MM, et al. A randomized trial of methotrexate versus azathioprine for severe atopic eczema. J Allergy Clin Immunol. 2011 Aug;128(2):353-9.Texto completo  Resumo

96. Li VCY, Chen KS, Yesudian BD. Subcutaneous methotrexate in the management of atopic dermatitis: a series of 12 patients. J Am Acad Dermatol. 2015 May 1;72(5 Suppl 1):AB75.

97. Weatherhead SC, Wahie S, Reynolds NJ, et al. An open-label, dose-ranging study of methotrexate for moderate-to-severe adult atopic eczema. Br J Dermatol. 2007 Feb;156(2):346-51. Resumo

98. Goujon C, Bérard F, Dahel K, et al. Methotrexate for the treatment of adult atopic dermatitis. Eur J Dermatol. 2006 Mar-Apr;16(2):155-8. Resumo

99. Dvorakova V, O'Regan GM, Irvine AD. Methotrexate for severe childhood atopic dermatitis: clinical experience in a tertiary center. Pediatr Dermatol. 2017 Sep;34(5):528-34.Texto completo  Resumo

100. Strober B, Mallya UG, Yang M, et al. Treatment Outcomes Associated With Dupilumab Use in Patients With Atopic Dermatitis: 1-Year Results From the RELIEVE-AD Study. JAMA Dermatol. 2021 Dec 15;:.Texto completo  Resumo

101. Sawangjit R, Dilokthornsakul P, Lloyd-Lavery A, et al. Systemic treatments for eczema: a network meta-analysis. Cochrane Database Syst Rev. 2020 Sep 14;9(9):CD013206.Texto completo  Resumo

102. Phan K, Smith SD. Mycophenolate mofetil and atopic dermatitis: systematic review and meta-analysis. J Dermatolog Treat. 2020 Dec;31(8):810-4. Resumo

103. George SM, Karanovic S, Harrison DA, et al. Interventions to reduce Staphylococcus aureus in the management of atopic eczema. Cochrane Database Syst Rev. 2019 Oct 29;2019(10):CD003871.Texto completo  Resumo

104. Klein PA, Clark RA. An evidence-based review of the efficacy of antihistamines in relieving pruritus in atopic dermatitis. Arch Dermatol. 1999 Dec;135(12):1522-5.Texto completo  Resumo

105. National Institute for Health and Care Excellence. Atopic eczema in under 12s: diagnosis and management. March 2021 [internet publication].Texto completo

106. Ferguson L, Futamura M, Vakirlis E, et al. Leukotriene receptor antagonists for eczema. Cochrane Database Syst Rev. 2018 Oct 21;10(10):CD011224.Texto completo  Resumo

107. Pickett K, Loveman E, Kalita N, et al. Educational interventions to improve quality of life in people with chronic inflammatory skin diseases: systematic reviews of clinical effectiveness and cost-effectiveness. Health Technol Assess. 2015 Oct;19(86):1-176.Texto completo  Resumo

108. Chisolm SS, Taylor SL, Balkrishnan R, et al. Written action plans: potential for improving outcomes in children with atopic dermatitis. J Am Acad Dermatol. 2008 Oct;59(4):677-83. Resumo

109. de Bes J, Legierse CM, Prinsen CA, et al. Patient education in chronic skin diseases: a systematic review. Acta Derm Venereol. 22011 Jan;91(1):12-7.Texto completo  Resumo

110. Carbone A, Siu A, Patel R. Pediatric atopic dermatitis: a review of the medical management. Ann Pharmacother. 2010 Sep;44(9):1448-58. Resumo

111. Wollenberg A, Blauvelt A, Guttman-Yassky E, et al. Tralokinumab for moderate-to-severe atopic dermatitis: results from two 52-week, randomized, double-blind, multicentre, placebo-controlled phase III trials (ECZTRA 1 and ECZTRA 2). Br J Dermatol. 2021 Mar;184(3):437-49.Texto completo  Resumo

112. Silverberg JI, Toth D, Bieber T, et al. Tralokinumab plus topical corticosteroids for the treatment of moderate-to-severe atopic dermatitis: results from the double-blind, randomized, multicentre, placebo-controlled phase III ECZTRA 3 trial. Br J Dermatol. 2021 Mar;184(3):450-463.Texto completo  Resumo

113. Guttman-Yassky E, Teixeira HD, Simpson EL, et al. Once-daily upadacitinib versus placebo in adolescents and adults with moderate-to-severe atopic dermatitis (Measure Up 1 and Measure Up 2): results from two replicate double-blind, randomised controlled phase 3 trials. Lancet. 2021 Jun 5;397(10290):2151-2168.Texto completo  Resumo

114. Reich K, Teixeira HD, de Bruin-Weller M, et al. Safety and efficacy of upadacitinib in combination with topical corticosteroids in adolescents and adults with moderate-to-severe atopic dermatitis (AD Up): results from a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet. 2021 Jun 5;397(10290):2169-2181.Texto completo  Resumo

115. Silverberg JI, Simpson EL, Thyssen JP, et al. Efficacy and safety of abrocitinib in patients with moderate-to-severe atopic dermatitis: a randomized clinical trial. JAMA Dermatol. 2020 Aug 1;156(8):863-73.Texto completo  Resumo

116. Silverberg JI, Thyssen JP, Simpson EL, et al. Impact of Oral Abrocitinib Monotherapy on Patient-Reported Symptoms and Quality of Life in Adolescents and Adults with Moderate-to-Severe Atopic Dermatitis: A Pooled Analysis of Patient-Reported Outcomes. Am J Clin Dermatol. 2021 Jul;22(4):541-554.Texto completo  Resumo

117. Thyssen JP, Yosipovitch G, Paul C, et al. Patient-reported outcomes from the JADE COMPARE randomized phase 3 study of abrocitinib in adults with moderate-to-severe atopic dermatitis. J Eur Acad Dermatol Venereol. 2021 Nov 15;:.Texto completo  Resumo

118. Kim BS, Howell MD, Sun K, et al. Treatment of atopic dermatitis with ruxolitinib cream (JAK1/JAK2 inhibitor) or triamcinolone cream. Allergy Clin Immunol. 2020 Feb;145(2):572-82.Texto completo  Resumo

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