Referências
Principais artigos
Ovadia C, Seed PT, Sklavounos A, et al. Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses. Lancet. 2019 Mar 2;393(10174):899-909.Texto completo Resumo
Girling J, Knight CL, Chappell L, et al. Intrahepatic cholestasis of pregnancy: green-top guideline no. 43 June 2022. BJOG. 2022 Aug 9 [Epub ahead of print].Texto completo Resumo
Glantz A, Marschall HU, Mattsson LA. Intrahepatic cholestasis of pregnancy: relationships between bile acid levels and fetal complication rates. Hepatology. 2004 Aug;40(2):467-74.Texto completo Resumo
Society for Maternal-Fetal Medicine; Lee RH, Greenberg M, Metz TD, et al. Society for Maternal-Fetal Medicine consult series #53: Intrahepatic cholestasis of pregnancy: replaces consult #13, April 2011. Am J Obstet Gynecol. 2021 Feb;224(2):B2-9.Texto completo Resumo
European Association for the Study of the Liver. Electronic address: easloffice@easloffice.eu, European Association for the Study of the Liver. EASL clinical practice guidelines on the management of liver diseases in pregnancy. J Hepatol. 2023 Sep;79(3):768-828.Texto completo Resumo
Walker KF, Chappell LC, Hague WM, et al. Pharmacological interventions for treating intrahepatic cholestasis of pregnancy. Cochrane Database Syst Rev. 2020 Jul 27;7(7):CD000493.Texto completo Resumo
Artigos de referência
1. Smith DD, Rood KM. Intrahepatic cholestasis of pregnancy. Clin Obstet Gynecol. 2020 Mar;63(1):134-51. Resumo
2. Ovadia C, Seed PT, Sklavounos A, et al. Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses. Lancet. 2019 Mar 2;393(10174):899-909.Texto completo Resumo
3. Stulic M, Culafic D, Boricic I, et al. Intrahepatic cholestasis of pregnancy: a case study of the rare onset in the first trimester. Medicina (Kaunas). 2019 Aug 9;55(8):454.Texto completo Resumo
4. Lin J, Gu W, Hou Y. Diagnosis and prognosis of early-onset intrahepatic cholestasis of pregnancy: a prospective study. J Matern Fetal Neonatal Med. 2019 Mar;32(6):997-1003. Resumo
5. Ovadia C, Williamson C. Intrahepatic cholestasis of pregnancy: recent advances. Clin Dermatol. 2016 May-Jun;34(3):327-34. Resumo
6. Kenyon AP, Tribe RM, Nelson-Piercy C, et al. Pruritus in pregnancy: a study of anatomical distribution and prevalence in relation to the development of obstetric cholestasis. Obstet Med. 2010 Mar;3(1):25-9.Texto completo Resumo
7. ICP Support. Myth busting. 2022 [internet publication].Texto completo
8. Steele G. Reflection on a pregnancy complicated by obstetric cholestasis. Pract Midwife. 2012 Oct;15(9):30-2. Resumo
9. Kenyon AP, Piercy CN, Girling J, et al. Pruritus may precede abnormal liver function tests in pregnant women with obstetric cholestasis: a longitudinal analysis. BJOG. 2001 Nov;108(11):1190-2. Resumo
10. Conti-Ramsden F, McEwan M, Hill R, et al. Detection of additional abnormalities or co-morbidities in women with suspected intrahepatic cholestasis of pregnancy. Obstet Med. 2020 Dec;13(4):185-91.Texto completo Resumo
11. Tuson A, Chambers J. Top 10 things to know about intrahepatic cholestasis of pregnancy (ICP). Essentially MIDIRS. 2013 Nov;4(10):27-30.Texto completo
12. Reyes H, Radrigan ME, Gonzalez MC, et al. Steatorrhea in patients with intrahepatic cholestasis of pregnancy. Gastroenterology. 1987 Sep;93(3):584-90.Texto completo Resumo
13. Sadler LC, Lane M, North R. Severe fetal intracranial haemorrhage during treatment with cholestyramine for intrahepatic cholestasis of pregnancy. Br J Obstet Gynaecol. 1995 Feb;102(2):169-70. Resumo
14. Girling J, Knight CL, Chappell L, et al. Intrahepatic cholestasis of pregnancy: green-top guideline no. 43 June 2022. BJOG. 2022 Aug 9 [Epub ahead of print].Texto completo Resumo
15. Bicocca MJ, Sperling JD, Chauhan SP. Intrahepatic cholestasis of pregnancy: review of six national and regional guidelines. Eur J Obstet Gynecol Reprod Biol. 2018 Dec;231:180-7. Resumo
16. Kenyon AP, Piercy CN, Girling J, et al. Obstetric cholestasis, outcome with active management: a series of 70 cases. BJOG. 2002 Mar;109(3):282-8. Resumo
17. Marschall HU, Wikström Shemer E, Ludvigsson JF, et al. Intrahepatic cholestasis of pregnancy and associated hepatobiliary disease: a population-based cohort study. Hepatology. 2013 Oct;58(4):1385-91.Texto completo Resumo
18. Martineau M, Raker C, Powrie R, et al. Intrahepatic cholestasis of pregnancy is associated with an increased risk of gestational diabetes. Eur J Obstet Gynecol Reprod Biol. 2014 May;176:80-5. Resumo
19. Mor M, Shmueli A, Krispin E, et al. Intrahepatic cholestasis of pregnancy as a risk factor for preeclampsia. Arch Gynecol Obstet. 2020 Mar;301(3):655-64. Resumo
20. Arafa A, Dong JY. Association between intrahepatic cholestasis of pregnancy and risk of gestational diabetes and preeclampsia: a systematic review and meta-analysis. Hypertens Pregnancy. 2020 Aug;39(3):354-60. Resumo
21. Glantz A, Marschall HU, Mattsson LA. Intrahepatic cholestasis of pregnancy: relationships between bile acid levels and fetal complication rates. Hepatology. 2004 Aug;40(2):467-74.Texto completo Resumo
22. Abedin P, Weaver JB, Egginton E. Intrahepatic cholestasis of pregnancy: prevalence and ethnic distribution. Ethn Health. 1999 Feb-May;4(1-2):35-7. Resumo
23. Chappell LC, Gurung V, Seed PT, et al. Ursodeoxycholic acid versus placebo, and early term delivery versus expectant management, in women with intrahepatic cholestasis of pregnancy: semifactorial randomised clinical trial. BMJ. 2012 Jun 13;344:e3799.Texto completo Resumo
24. Reyes H. Sex hormones and bile acids in intrahepatic cholestasis of pregnancy. Hepatology. 2008 Feb;47(2):376-9.Texto completo Resumo
25. Allen AM, Kim WR, Larson JJ, et al. The epidemiology of liver diseases unique to pregnancy in a US community: a population-based study. Clin Gastroenterol Hepatol. 2016 Feb;14(2):287-94.Texto completo Resumo
26. Marathe JA, Lim WH, Metz MP, et al. A retrospective cohort review of intrahepatic cholestasis of pregnancy in a South Australian population. Eur J Obstet Gynecol Reprod Biol. 2017 Nov;218:33-8. Resumo
27. Rook M, Vargas J, Caughey A, et al. Fetal outcomes in pregnancies complicated by intrahepatic cholestasis of pregnancy in a Northern California cohort. PLoS One. 2012;7(3):e28343.Texto completo Resumo
28. Luo XL, Zhang WY. Obstetrical disease spectrum in China: an epidemiological study of 111,767 cases in 2011. Chin Med J (Engl). 2015 May 5;128(9):1137-46.Texto completo Resumo
29. Bull LN, Hu D, Shah S, et al. Intrahepatic cholestasis of pregnancy (ICP) in U.S. Latinas and Chileans: clinical features, ancestry analysis, and admixture mapping. PLoS One. 2015 May 5;10(6):e0131211.Texto completo Resumo
30. Lee RH, Goodwin TM, Greenspoon J, et al. The prevalence of intrahepatic cholestasis of pregnancy in a primarily Latina Los Angeles population. J Perinatol. 2006 Sep;26(9):527-32. Resumo
31. Turunen K, Helander K, Mattila KJ, et al. Intrahepatic cholestasis of pregnancy is common among patients' first-degree relatives. Acta Obstet Gynecol Scand. 2013 Sep;92(9):1108-10.Texto completo Resumo
32. Dixon PH, van Mil SW, Chambers J, et al. Contribution of variant alleles of ABCB11 to susceptibility to intrahepatic cholestasis of pregnancy. Gut. 2009 Apr;58(4):537-44. Resumo
33. Wasmuth HE, Glantz A, Keppeler H, et al. Intrahepatic cholestasis of pregnancy: the severe form is associated with common variants of the hepatobiliary phospholipid transporter ABCB4 gene. Gut. 2007 Feb;56(2):265-70.Texto completo Resumo
34. Dixon PH, Sambrotta M, Chambers J, et al. An expanded role for heterozygous mutations of ABCB4, ABCB11, ATP8B1, ABCC2 and TJP2 in intrahepatic cholestasis of pregnancy. Sci Rep. 2017 Sep 18;7(1):11823.Texto completo Resumo
35. Van Mil SW, Milona A, Dixon PH, et al. Functional variants of the central bile acid sensor FXR identified in intrahepatic cholestasis of pregnancy. Gastroenterology. 2007 Aug;133(2):507-16.Texto completo Resumo
36. Cabrerizo R, Castaño GO, Burgueño AL, et al. Promoter DNA methylation of farnesoid X receptor and pregnane X receptor modulates the intrahepatic cholestasis of pregnancy phenotype. PLoS One. 2014 Jan 31;9(1):e87697.Texto completo Resumo
37. Keitel V, Dröge C, Stepanow S, et al. Intrahepatic cholestasis of pregnancy (ICP): case report and review of the literature. Z Gastroenterol. 2016 Dec;54(12):1327-33. Resumo
38. Schock H, Zeleniuch-Jacquotte A, Lundin E, et al. Hormone concentrations throughout uncomplicated pregnancies: a longitudinal study. BMC Pregnancy Childbirth. 2016 Jul 4;16(1):146.Texto completo Resumo
39. Williamson C, Hems LM, Goulis DG, et al. Clinical outcome in a series of cases of obstetric cholestasis identified via a patient support group. BJOG. 2004 Jul;111(7):676-81. Resumo
40. Zipori Y, Bachar G, Farago N, et al. Vaginal progesterone treatment for the prevention of preterm birth and intrahepatic cholestasis of pregnancy: a case-control study. Eur J Obstet Gynecol Reprod Biol. 2020 Oct;253:117-20. Resumo
41. Perrault F, Echelard P, Viens D, et al. Contraceptive vaginal ring-induced cholestasis in a patient with a history of intrahepatic cholestasis of pregnancy. Clin Res Hepatol Gastroenterol. 2021 Jul;45(4):101475. Resumo
42. Chen Y, Vasilenko A, Song X, et al. Estrogen and estrogen receptor-α-mediated transrepression of bile salt export pump. Mol Endocrinol. 2015 Apr;29(4):613-26.Texto completo Resumo
43. Miszczuk GS, Barosso IR, Larocca MC, et al. Mechanisms of canalicular transporter endocytosis in the cholestatic rat liver. Biochim Biophys Acta Mol Basis Dis. 2018 Apr;1864(4 pt a):1072-85.Texto completo Resumo
44. Abu-Hayyeh S, Martinez-Becerra P, Sheikh Abdul Kadir SH, et al. Inhibition of Na+-taurocholate co-transporting polypeptide-mediated bile acid transport by cholestatic sulfated progesterone metabolites. J Biol Chem. 2010 May 28;285(22):16504-12.Texto completo Resumo
45. Vallejo M, Briz O, Serrano MA, et al. Potential role of trans-inhibition of the bile salt export pump by progesterone metabolites in the etiopathogenesis of intrahepatic cholestasis of pregnancy. J Hepatol. 2006 Jun;44(6):1150-7. Resumo
46. Abu-Hayyeh S, Papacleovoulou G, Lövgren-Sandblom A, et al. Intrahepatic cholestasis of pregnancy levels of sulfated progesterone metabolites inhibit farnesoid X receptor resulting in a cholestatic phenotype. Hepatology. 2013 Feb;57(2):716-26.Texto completo Resumo
47. Song X, Vasilenko A, Chen Y, et al. Transcriptional dynamics of bile salt export pump during pregnancy: mechanisms and implications in intrahepatic cholestasis of pregnancy. Hepatology. 2014 Dec;60(6):1993-2007.Texto completo Resumo
48. Dixon PH, Levine AP, Cebola I, et al. GWAS meta-analysis of intrahepatic cholestasis of pregnancy implicates multiple hepatic genes and regulatory elements. Nat Commun. 2022 Aug 17;13(1):4840.Texto completo Resumo
49. Karjalainen MK, Karthikeyan S, Oliver-Williams C, et al. Genome-wide characterization of circulating metabolic biomarkers. Nature. 2024 Apr;628(8006):130-8.Texto completo Resumo
50. Liu X, Landon MB, Chen Y, et al. Perinatal outcomes with intrahepatic cholestasis of pregnancy in twin pregnancies. J Matern Fetal Neonatal Med. 2016;29(13):2176-81. Resumo
51. Lei LL, Lan YL, Wang SY, et al. Perinatal complications and live-birth outcomes following assisted reproductive technology: a retrospective cohort study. Chin Med J (Engl). 2019 Oct 20;132(20):2408-16.Texto completo Resumo
52. Gençosmanoğlu Türkmen G, Vural Yilmaz Z, Dağlar K, et al. Low serum vitamin D level is associated with intrahepatic cholestasis of pregnancy. J Obstet Gynaecol Res. 2018 Sep;44(9):1712-8. Resumo
53. Reyes H, Báez ME, González MC, et al. Selenium, zinc and copper plasma levels in intrahepatic cholestasis of pregnancy, in normal pregnancies and in healthy individuals, in Chile. J Hepatol. 2000 Apr;32(4):542-9. Resumo
54. Kremer AE, Bolier R, Dixon PH, et al. Autotaxin activity has a high accuracy to diagnose intrahepatic cholestasis of pregnancy. J Hepatol. 2015 Apr;62(4):897-904. Resumo
55. Abu-Hayyeh S, Ovadia C, Lieu T, et al. Prognostic and mechanistic potential of progesterone sulfates in intrahepatic cholestasis of pregnancy and pruritus gravidarum. Hepatology. 2016 Apr;63(4):1287-98.Texto completo Resumo
56. Dann AT, Kenyon AP, Wierzbicki AS, et al. Plasma lipid profiles of women with intrahepatic cholestasis of pregnancy. Obstet Gynecol. 2006 Jan;107(1):106-14. Resumo
57. Martineau MG, Raker C, Dixon PH, et al. The metabolic profile of intrahepatic cholestasis of pregnancy is associated with impaired glucose tolerance, dyslipidemia, and increased fetal growth. Diabetes Care. 2015 Feb;38(2):243-8.Texto completo Resumo
58. Hao ZM, Ye YF, Zhang YK, et al. Lipoprotein lipase and lipid profiles in plasma and placenta from normal pregnancies compared with patients with intrahepatic cholestasis of pregnancy. Eur J Obstet Gynecol Reprod Biol. 2016 Aug;203:279-85. Resumo
59. Geenes V, Lövgren-Sandblom A, Benthin L, et al. The reversed feto-maternal bile acid gradient in intrahepatic cholestasis of pregnancy is corrected by ursodeoxycholic acid. PLoS One. 2014 Jan 8;9(1):e83828.Texto completo Resumo
60. Campos GA, Guerra FA, Israel EJ. Effects of cholic acid infusion in fetal lambs. Acta Obstet Gynecol Scand. 1986;65(1):23-6. Resumo
61. Germain AM, Kato S, Carvajal JA, et al. Bile acids increase response and expression of human myometrial oxytocin receptor. Am J Obstet Gynecol. 2003 Aug;189(2):577-82. Resumo
62. Kirwan WO, Smith AN, Mitchell WD, et al. Bile acids and colonic motility in the rabbit and the human. Gut. 1975 Nov;16(11):894-902.Texto completo Resumo
63. Zecca E, De Luca D, Baroni S, et al. Bile acid-induced lung injury in newborn infants: a bronchoalveolar lavage fluid study. Pediatrics. 2008 Jan;121(1):e146-9. Resumo
64. Herraez E, Lozano E, Poli E, et al. Role of macrophages in bile acid-induced inflammatory response of fetal lung during maternal cholestasis. J Mol Med (Berl). 2014 Apr;92(4):359-72. Resumo
65. Reid R, Ivey KJ, Rencoret RH, et al. Fetal complications of obstetric cholestasis. Br Med J. 1976 Apr 10;1(6014):870-2.Texto completo Resumo
66. He J, Chen L, Liang C. Clinical analysis of fetal death cases in intrahepatic cholestasis of pregnancy [in Chinese]. Zhonghua Fu Chan Ke Za Zhi. 2011 May;46(5):333-7. Resumo
67. Lee RH, Incerpi MH, Miller DA, et al. Sudden fetal death in intrahepatic cholestasis of pregnancy. Obstet Gynecol. 2009 Feb;113(2 pt 2):528-31. Resumo
68. Williamson C, Gorelik J, Eaton BM, et al. The bile acid taurocholate impairs rat cardiomyocyte function: a proposed mechanism for intra-uterine fetal death in obstetric cholestasis. Clin Sci (Lond). 2001 Apr;100(4):363-9. Resumo
69. Ataalla WM, Ziada DH, Gaber R, et al. The impact of total bile acid levels on fetal cardiac function in intrahepatic cholestasis of pregnancy using fetal echocardiography: a tissue Doppler imaging study. J Matern Fetal Neonatal Med. 2016;29(9):1445-50. Resumo
70. Strehlow SL, Pathak B, Goodwin TM, et al. The mechanical PR interval in fetuses of women with intrahepatic cholestasis of pregnancy. Am J Obstet Gynecol. 2010 Nov;203(5):455. Resumo
71. Zhang LJ, Xiang H, Ding YL. Influence of total bile acid in maternal serum and cord blood on neonatal cardiac function from intrahepatic cholestasis of pregnancy [in Chinese]. Zhonghua Fu Chan Ke Za Zhi. 2009 Mar;44(3):188-90. Resumo
72. Vasavan T, Deepak S, Jayawardane IA, et al. Fetal cardiac dysfunction in intrahepatic cholestasis of pregnancy is associated with elevated serum bile acid concentrations. J Hepatol. 2021 May;74(5):1087-96.Texto completo Resumo
73. Dolinsky BM, Zelig CM, Paonessa DJ, et al. Effect of taurocholic acid on fetoplacental arterial pressures in a dual perfusion placental cotyledon model: a novel approach to intrahepatic cholestasis of pregnancy. J Reprod Med. 2014 Jul-Aug;59(7-8):367-70. Resumo
74. Wijarnpreecha K, Thongprayoon C, Sanguankeo A, et al. Hepatitis C infection and intrahepatic cholestasis of pregnancy: a systematic review and meta-analysis. Clin Res Hepatol Gastroenterol. 2017 Feb;41(1):39-45. Resumo
75. Wu K, Wang H, Li S, et al. Maternal hepatitis B infection status and adverse pregnancy outcomes: a retrospective cohort analysis. Arch Gynecol Obstet. 2020 Sep;302(3):595-602. Resumo
76. Society for Maternal-Fetal Medicine; Lee RH, Greenberg M, Metz TD, et al. Society for Maternal-Fetal Medicine consult series #53: Intrahepatic cholestasis of pregnancy: replaces consult #13, April 2011. Am J Obstet Gynecol. 2021 Feb;224(2):B2-9.Texto completo Resumo
77. Estiú MC, Frailuna MA, Otero C, et al. Relationship between early onset severe intrahepatic cholestasis of pregnancy and higher risk of meconium-stained fluid. PLoS One. 2017 Apr 24;12(4):e0176504.Texto completo Resumo
78. Zhang Y, Shi D, Abagyan R, et al. Population scale retrospective analysis reveals potential risk of cholestasis in pregnant women taking omeprazole, lansoprazole, and amoxicillin. Interdiscip Sci. 2019 Jun;11(2):273-81.Texto completo Resumo
79. European Association for the Study of the Liver. Electronic address: easloffice@easloffice.eu, European Association for the Study of the Liver. EASL clinical practice guidelines on the management of liver diseases in pregnancy. J Hepatol. 2023 Sep;79(3):768-828.Texto completo Resumo
80. Manzotti C, Casazza G, Stimac T, et al. Total serum bile acids or serum bile acid profile, or both, for the diagnosis of intrahepatic cholestasis of pregnancy. Cochrane Database Syst Rev. 2019 Jul 5;7(7):CD012546.Texto completo Resumo
81. Furrer R, Winter K, Schäffer L, et al. Postpartum blood loss in women treated for intrahepatic cholestasis of pregnancy. Obstet Gynecol. 2016 Nov;128(5):1048-52.Texto completo Resumo
82. Lewiecki EM, Rahman F. Pruritus. A manifestation of iron deficiency. JAMA. 1976 Nov 15;236(20):2319-20. Resumo
83. Lundåsen T, Gälman C, Angelin B, et al. Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man. J Intern Med. 2006 Dec;260(6):530-6.Texto completo Resumo
84. Smith DD, Kiefer MK, Lee AJ, et al. Effect of fasting on total bile acid levels in pregnancy. Obstet Gynecol. 2020 Dec;136(6):1204-10. Resumo
85. Mitchell AL, Ovadia C, Syngelaki A, et al. Re-evaluating diagnostic thresholds for intrahepatic cholestasis of pregnancy: case-control and cohort study. BJOG. 2021 Sep;128(10):1635-44.Texto completo Resumo
86. European Association for the Study of the Liver. EASL clinical practice guidelines: drug-induced liver injury. J Hepatol. 2019 Jun;70(6):1222-61.Texto completo Resumo
87. Royal College of Obstetricians and Gynaecologists. Guidance for maternal medicine services in the coronavirus (COVID-19) pandemic. Dec 2020 [internet publication].Texto completo
88. Di Mascio D, Quist-Nelson J, Riegel M, et al. Perinatal death by bile acid levels in intrahepatic cholestasis of pregnancy: a systematic review. J Matern Fetal Neonatal Med. 2021 Nov;34(21):3614-22. Resumo
89. Walker KF, Chappell LC, Hague WM, et al. Pharmacological interventions for treating intrahepatic cholestasis of pregnancy. Cochrane Database Syst Rev. 2020 Jul 27;7(7):CD000493.Texto completo Resumo
90. Manna LB, Ovadia C, Lövgren-Sandblom A, et al. Enzymatic quantification of total serum bile acids as a monitoring strategy for women with intrahepatic cholestasis of pregnancy receiving ursodeoxycholic acid treatment: a cohort study. BJOG. 2019 Dec;126(13):1633-40.Texto completo Resumo
91. Chappell LC, Bell JL, Smith A, et al. Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): a randomised controlled trial. Lancet. 2019 Sep 7;394(10201):849-60.Texto completo Resumo
92. Ovadia C, Sajous J, Seed PT, et al. Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a systematic review and individual participant data meta-analysis. Lancet Gastroenterol Hepatol. 2021 Jul;6(7):547-58.Texto completo Resumo
93. Hague WM, Briley A, Callaway L, et al. Intrahepatic cholestasis of pregnancy - diagnosis and management: a consensus statement of the Society of Obstetric Medicine of Australia and New Zealand (SOMANZ): Executive summary. Aust N Z J Obstet Gynaecol. 2023 Oct;63(5):656-65.Texto completo Resumo
94. Kondrackiene J, Beuers U, Kupcinskas L. Efficacy and safety of ursodeoxycholic acid versus cholestyramine in intrahepatic cholestasis of pregnancy. Gastroenterology. 2005 Sep;129(3):894-901.Texto completo Resumo
95. Zhang L, Liu XH, Qi HB, et al. Ursodeoxycholic acid and S-adenosylmethionine in the treatment of intrahepatic cholestasis of pregnancy: a multi-centered randomized controlled trial. Eur Rev Med Pharmacol Sci. 2015 Oct;19(19):3770-6.Texto completo Resumo
96. Binser T, Salaj P, Zima T, et al. Randomized prospective comparative study of ursodeoxycholic acid and S-adenosyl-L-methionine in the treatment of intrahepatic cholestasis of pregnancy. J Perinat Med. 2006;34(5):383-91. Resumo
97. Geenes V, Chambers J, Khurana R, et al. Rifampicin in the treatment of severe intrahepatic cholestasis of pregnancy. Eur J Obstet Gynecol Reprod Biol. 2015 Jun;189:59-63. Resumo
98. Glantz A, Marschall HU, Lammert F, et al. Intrahepatic cholestasis of pregnancy: a randomized controlled trial comparing dexamethasone and ursodeoxycholic acid. Hepatology. 2005 Dec;42(6):1399-405.Texto completo Resumo
99. Ovadia C, Lövgren-Sandblom A, Edwards LA, et al. Therapeutic plasma exchange as a novel treatment for severe intrahepatic cholestasis of pregnancy: case series and mechanism of action. J Clin Apher. 2018 Dec;33(6):638-44. Resumo
100. Puljic A, Kim E, Page J, et al. The risk of infant and fetal death by each additional week of expectant management in intrahepatic cholestasis of pregnancy by gestational age. Am J Obstet Gynecol. 2015 May;212(5):667.e1-5. Resumo
101. Lo JO, Shaffer BL, Allen AJ, et al. Intrahepatic cholestasis of pregnancy and timing of delivery. J Matern Fetal Neonatal Med. 2015;28(18):2254-8. Resumo
102. Geenes V, Chappell LC, Seed PT, et al. Association of severe intrahepatic cholestasis of pregnancy with adverse pregnancy outcomes: a prospective population-based case-control study. Hepatology. 2014 Apr;59(4):1482-91.Texto completo Resumo
103. DeLeon A, De Oliveira GS, Kalayil M, et al. The incidence of coagulopathy in pregnant patients with intrahepatic cholestasis: should we delay or avoid neuraxial analgesia? J Clin Anesth. 2014 Dec;26(8):623-7. Resumo
104. Wikström Shemer EA, Stephansson O, Thuresson M, et al. Intrahepatic cholestasis of pregnancy and cancer, immune-mediated and cardiovascular diseases: a population-based cohort study. J Hepatol. 2015 Aug;63(2):456-61. Resumo
105. Hämäläinen ST, Turunen K, Mattila KJ, et al. Intrahepatic cholestasis of pregnancy and associated causes of death: a cohort study with follow-up of 27-46 years. BMC Womens Health. 2018 Jun 19;18(1):98.Texto completo Resumo
106. Chen S, Ahlqvist VH, Sjöqvist H, et al. Maternal intrahepatic cholestasis of pregnancy and neurodevelopmental conditions in offspring: a population-based cohort study of 2 million Swedish children. PLoS Med. 2024 Jan;21(1):e1004331.Texto completo Resumo
107. Papacleovoulou G, Abu-Hayyeh S, Nikolopoulou E, et al. Maternal cholestasis during pregnancy programs metabolic disease in offspring. J Clin Invest. 2013 Jul;123(7):3172-81.Texto completo Resumo
108. Zhao C, Wang X, Cong Y, et al. Effects of bile acids and the bile acid receptor FXR agonist on the respiratory rhythm in the in vitro brainstem medulla slice of neonatal Sprague-Dawley rats. PLoS One. 2014 Nov 18;9(11):e112212.Texto completo Resumo
109. National Institute for Health and Care Excellence. Preterm labour and birth. Jun 2022 [internet publication].Texto completo
110. Stock SJ, Thomson AJ, Papworth S, et al. Antenatal corticosteroids to reduce neonatal morbidity and mortality: green-top guideline no. 74. BJOG. 2022 Jul;129(8):e35-60.Texto completo Resumo
111. American College of Obstetricians and Gynecologists. Committee opinion no. 455: magnesium sulfate before anticipated preterm birth for neuroprotection. Obstet Gynecol. 2010 Mar;115(3):669-71.Texto completo Resumo
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