Doença de Whipple

Referências

Principais artigos

Schneider T, Moos V, Loddenkemper C, et al. Whipple's disease: new aspects of pathogenesis and treatment. Lancet Infect Dis. 2008 Mar;8(3):179-90. Resumo

Fenollar F, Puechal X, Raoult D. Whipple's disease. N Engl J Med. 2007 Jan 4;356(1):55-66.

Dobbins WO. Whipple's disease. Springfield, IL: Thomas; 1987.

Louis ED, Lynch T, Kaufmann P, et al. Diagnostic guidelines in central nervous system Whipple's disease. Ann Neurol. 1996 Oct;40(4):561-8. Resumo

Feurle GE, Junga NS, Marth T. Efficacy of ceftriaxone or meropenem as initial therapies in Whipple's disease. Gastroenterology. 2010 Feb;138(2):478-86; quiz 11-2.Texto completo  Resumo

Feurle GE, Moos V, Bläker H, et al. Intravenous ceftriaxone, followed by 12 or three months of oral treatment with trimethoprim-sulfamethoxazole in Whipple's disease. J Infect. 2013 Mar;66(3):263-70. Resumo

Artigos de referência

1. Raoult D, Ogata H, Audic S, et al. Tropheryma whipplei twist: a human pathogenic Actinobacteria with a reduced genome. Genome Res. 2003 Aug;13(8):1800-9.Texto completo  Resumo

2. Bentley SD, Maiwald M, Murphy LD, et al. Sequencing and analysis of the genome of the Whipple's disease bacterium Tropheryma whipplei. Lancet. 2003 Feb 22;361(9358):637-44. Resumo

3. Schoniger-Hekele M, Petermann D, Weber B, et al. Tropheryma whipplei in the environment: survey of sewage plant influxes and sewage plant workers. Appl Environ Microbiol. 2007 Mar;73(6):2033-5.Texto completo  Resumo

4. Maiwald M, Schuhmacher F, Ditton HJ, et al. Environmental occurrence of the Whipple's disease bacterium (Tropheryma whippelii). Appl Environ Microbiol. 1998 Feb;64(2):760-2.Texto completo  Resumo

5. Fenollar F, Trani M, Davoust B, et al. Prevalence of asymptomatic Tropheryma whipplei carriage among humans and nonhuman primates. J Infect Dis. 2008 Mar 15;197(6):880-7.Texto completo  Resumo

6. Ehrbar HU, Bauerfeind P, Dutly F, et al. PCR-positive tests for Tropheryma whippelii in patients without Whipple's disease. Lancet. 1999 Jun 26;353(9171):2214. Resumo

7. Amsler L, Bauernfeind P, Nigg C, et al. Prevalence of Tropheryma whipplei DNA in patients with various gastrointestinal diseases and in healthy controls. Infection. 2003 Mar;31(2):81-5. Resumo

8. Maibach RC, Dutly F, Altwegg M. Detection of Tropheryma whipplei DNA in feces by PCR using a target capture method. J Clin Microbiol. 2002 Jul;40(7):2466-71.Texto completo  Resumo

9. Zinkernagel AS, Gmur R, Fenner L, et al. Marginal and subgingival plaque: a natural habitat of Tropheryma whipplei? Infection. 2003 Mar;31(2):86-91. Resumo

10. Rolain JM, Fenollar F, Raoult D. False positive PCR detection of Tropheryma whipplei in the saliva of healthy people. BMC Microbiol. 2007 May 29;7:48.Texto completo  Resumo

11. Schneider T, Moos V, Loddenkemper C, et al. Whipple's disease: new aspects of pathogenesis and treatment. Lancet Infect Dis. 2008 Mar;8(3):179-90. Resumo

12. Fenollar F, Puechal X, Raoult D. Whipple's disease. N Engl J Med. 2007 Jan 4;356(1):55-66.

13. Dobbins WO 3rd. Is there an immune deficit in Whipple's disease? Dig Dis Sci. 1981 Mar;26(3):247-52. Resumo

14. Dobbins WO. Whipple's disease. Springfield, IL: Thomas; 1987.

15. Gubler JG, Kuster M, Dutly F, et al. Whipple endocarditis without overt gastrointestinal disease: report of four cases. Ann Intern Med. 1999 Jul 20;131(2):112-6. Resumo

16. Weber U, Morf MH, Gubler JG, et al. Spondylodiscitis as the first manifestation of Whipple's disease: a removal worker with chronic low back pain. Clin Rheumatol. 2003 Dec;22(6):443-6. Resumo

17. Pruss H, Katchanov J, Zschenderlein R, et al. A patient with cerebral Whipple disease with gastric involvement but no gastrointestinal symptoms: a consequence of local protective immunity? J Neurol Neurosurg Psychiatry. 2007 Aug;78(8):896-8. Resumo

18. Feurle GE, Moos V, Schinnerling K, et al. The immune reconstitution inflammatory syndrome in Whipple disease: a cohort study. Ann Int Med. 2010 Dec 7;153(11):710-7. Resumo

19. Elchert JA, Mansoor E, Abou-Saleh M, et al. Epidemiology of Whipple's Disease in the USA Between 2012 and 2017: A Population-Based National Study. Dig Dis Sci. 2019 May;64(5):1305-11.Texto completo  Resumo

20. Ahmad AI, Wikholm C, Pothoulakis I, et al. Whipple's disease review, prevalence, mortality, and characteristics in the United States: a cross-sectional national inpatient study. Medicine (Baltimore). 2022 Dec 9;101(49):e32231.Texto completo  Resumo

21. von Herbay A, Otto HF, Stolte M, et al. Epidemiology of Whipple's disease in Germany: analysis of 110 patients diagnosed in 1965-95. Scand J Gastroenterol. 1997 Jan;32(1):52-7. Resumo

22. Raoult D, Fenollar F, Rolain JM, et al. Tropheryma whipplei in children with gastroenteritis. Emerg Infect Dis. 2010 May;16(5):776-82.Texto completo  Resumo

23. Fenollar F, Trape JF, Bassene H, et al. Tropheryma whipplei in fecal samples from children, Senegal. Emerg Infect Dis. 2009 Jun;15(6):922-4.Texto completo  Resumo

24. Moos V, Kunkel D, Marth T, et al. Reduced peripheral and mucosal Tropheryma whipplei-specific Th1 response in patients with Whipple's disease. J Immunol. 2006 Aug 1;177(3):2015-22.Texto completo  Resumo

25. Bonhomme CJ, Renesto P, Nandi S, et al. Serological microarray for a paradoxical diagnostic of Whipple's disease. Eur J Clin Microbiol Infect Dis. 2008 Oct;27(10):959-68. Resumo

26. Martinetti M, Biagi F, Badulli C, et al. The HLA alleles DRB1*13 and DQB1*06 are associated to Whipple's disease. Gastroenterology. 2009 Jun;136(7):2289-94. Resumo

27. Marth T, Raoult D. Whipple's disease. Lancet. 2003 Jan 18;361(9353):239-46. Resumo

28. Desnues B, Ihrig M, Raoult D, et al. Whipple's disease: a macrophage disease. Clin Vaccine Immunol. 2006 Feb;13(2):170-8.Texto completo  Resumo

29. Bai JC, Sen L, Diez R, et al. Impaired monocyte function in patients successfully treated for Whipple's disease. Acta Gastroenterol Latinoam. 1996;26(2):85-9. Resumo

30. Lukacs G, Dobi S, Szabo M. A case of Whipple's disease with repeated operations for ileus and complete cure. Acta Hepatogastroenterol (Stuttg). 1978 Jun;25(3):238-42. Resumo

31. Ghigo E, Capo C, Aurouze M, et al. Survival of Tropheryma whipplei, the agent of Whipple's disease, requires phagosome acidification. Infect Immun. 2002 Mar;70(3):1501-6.Texto completo  Resumo

32. Marth T, Roux M, von Herbay A, et al. Persistent reduction of complement receptor 3 alpha-chain expressing mononuclear blood cells and transient inhibitory serum factors in Whipple's disease. Clin Immunol Immunopathol. 1994 Aug;72(2):217-26. Resumo

33. Ectors N, Geboes K, De Vos R, et al. Whipple's disease: a histological, immunocytochemical and electronmicroscopic study of the immune response in the small intestinal mucosa. Histopathology. 1992 Jul;21(1):1-12. Resumo

34. Kalt A, Schneider T, Ring S, et al. Decreased levels of interleukin-12p40 in the serum of patients with Whipple's disease. Int J Colorectal Dis. 2006 Mar;21(2):114-20. Resumo

35. Marth T, Neurath M, Cuccherini BA, et al. Defects of monocyte interleukin 12 production and humoral immunity in Whipple's disease. Gastroenterology. 1997 Aug;113(2):442-8. Resumo

36. Desnues B, Lepidi H, Raoult D, et al. Whipple disease: intestinal infiltrating cells exhibit a transcriptional pattern of M2/alternatively activated macrophages. J Infect Dis. 2005 Nov 1;192(9):1642-6.Texto completo  Resumo

37. Moos V, Schmidt C, Geelhaar A, et al. Impaired immune functions of monocytes and macrophages in Whipple's disease. Gastroenterology. 2010 Jan;138(1):210-20. Resumo

38. Marth T, Kleen N, Stallmach A, et al. Dysregulated peripheral and mucosal Th1/Th2 response in Whipple's disease. Gastroenterology. 2002 Nov;123(5):1468-77. Resumo

39. Schoedon G, Goldenberger D, Forrer R, et al. Deactivation of macrophages with interleukin-4 is the key to the isolation of Tropheryma whippelii. J Infect Dis. 1997 Sep;176(3):672-7. Resumo

40. Friedmann AC, Perera GK, Jayaprakasam A, et al. Whipple's disease presenting with symmetrical panniculitis. Br J Dermatol. 2004 Oct;151(4):907-11. Resumo

41. Tarroch X, Vives P, Salas A, et al. Subcutaneous nodules in Whipple's disease. J Cutan Pathol. 2001 Aug;28(7):368-70. Resumo

42. Helliwell TR, Appleton RE, Mapstone NC, et al. Dermatomyositis and Whipple's disease. Neuromuscul Disord. 2000 Jan;10(1):46-51. Resumo

43. Kwee D, Fields JP, King LE Jr. Subcutaneous Whipple's disease. J Am Acad Dermatol. 1987 Jan;16(1 Pt 2):188-90. Resumo

44. Cho C, Linscheer WG, Hirschkorn MA, et al. Sarcoidlike granulomas as an early manifestation of Whipple's disease. Gastroenterology. 1984 Oct;87(4):941-7. Resumo

45. Viteri AL, Stinson JC, Barnes MC, et al. Rod-shaped organism in the liver of a patient with Whipple's disease. Dig Dis Sci. 1979 Jul;24(7):560-4. Resumo

46. Puget M, Iwaz J, Tristan A, et al. Whipple's disease with muscle impairment. Muscle Nerve. 2006 Dec;34(6):794-8. Resumo

47. Misbah SA, Stirzaker D, Ozols B, et al. Anonymous survey of blood donors by polymerase chain reaction for Tropheryma whippelii. QJM. 1999 Jan;92(1):61.Texto completo  Resumo

48. Mahnel R, Kalt A, Ring S, et al. Immunosuppressive therapy in Whipple's disease patients is associated with the appearance of gastrointestinal manifestations. Am J Gastroenterol. 2005 May;100(5):1167-73. Resumo

49. Biagi F, Trotta L, Corazza GR. Whipple's disease. Intern Emerg Med. 2012 Oct;7 Suppl 3:S209-13. Resumo

50. Louis ED, Lynch T, Kaufmann P, et al. Diagnostic guidelines in central nervous system Whipple's disease. Ann Neurol. 1996 Oct;40(4):561-8. Resumo

51. Keinath RD, Merrell DE, Vlietstra R, et al. Antibiotic treatment and relapse in Whipple's disease: long-term follow-up of 88 patients. Gastroenterology. 1985 Jun;88(6):1867-73. Resumo

52. Durand DV, Lecomte C, Cathebras P, et al. Whipple disease: clinical review of 52 cases. The SNFMI Research Group on Whipple Disease. Societe Nationale Francaise de Medecine Interne. Medicine (Baltimore). 1997 May;76(3):170-84. Resumo

53. Gerard A, Sarrot-Reynauld F, Liozon E, et al. Neurologic presentation of Whipple disease: report of 12 cases and review of the literature. Medicine (Baltimore). 2002 Nov;81(6):443-57. Resumo

54. Messori A, Di Bella P, Polonara G, et al. An unusual spinal presentation of Whipple disease. AJNR Am J Neuroradiol. 2001 May;22(5):1004-8.Texto completo  Resumo

55. Mendel E, Khoo LT, Go JL, et al. Intracerebral Whipple's disease diagnosed by stereotactic biopsy: a case report and review of the literature. Neurosurgery. 1999 Jan;44(1):203-9. Resumo

56. Feurle GE, Utz G, Kies D, et al. Neurological manifestations of Whipple's disease. Schweiz Med Wochenschr. 1976 Nov 20;106(47):1642-6. Resumo

57. Feurle GE, Volk B, Waldherr R. Cerebral Whipple's disease with negative jejunal histology. N Engl J Med. 1979 Apr 19;300(16):907-8. Resumo

58. Fenollar F, Raoult D. Whipple's disease. Clin Vaccine Immunol. 2001;8(1):1-8.Texto completo  Resumo

59. Fenollar F, Raoult D. Molecular techniques in Whipple's disease. Expert Rev Mol Diagn. 2001 Sep;1(3):299-309. Resumo

60. Maiwald M, von Herbay A, Persing DH, et al. Tropheryma whippelii DNA is rare in the intestinal mucosa of patients without other evidence of Whipple disease. Ann Intern Med. 2001 Jan 16;134(2):115-9.Texto completo  Resumo

61. Misbah SA, Mapstone NP. Whipple's disease revisited. J Clin Pathol. 2000 Oct;53(10):750-5.Texto completo  Resumo

62. Krober SM, Kaiserling E, Horny HP, et al. Primary diagnosis of Whipple's disease in bone marrow. Hum Pathol. 2004 Apr;35(4):522-5. Resumo

63. Walter R, Bachmann SP, Schaffner A, et al. Bone marrow involvement in Whipple's disease: rarely reported, but really rare? Br J Haematol. 2001 Mar;112(3):677-9.Texto completo  Resumo

64. Lepidi H, Fenollar F, Gerolami R, et al. Whipple's disease: immunospecific and quantitative immunohistochemical study of intestinal biopsy specimens. Hum Pathol. 2003 Jun;34(6):589-96. Resumo

65. Baisden BL, Lepidi H, Raoult D, et al. Diagnosis of Whipple disease by immunohistochemical analysis: a sensitive and specific method for the detection of Tropheryma whipplei (the Whipple bacillus) in paraffin-embedded tissue. Am J Clin Pathol. 2002 Nov;118(5):742-8. Resumo

66. Sinha S, Satishchandra P, Gayathri N, et al. Progressive myoclonic epilepsy: a clinical, electrophysiological and pathological study from South India. J Neurol Sci. 2007 Jan 15;252(1):16-23. Resumo

67. Giuffre B, Parini R, Rizzuti T, et al. Severe neonatal onset of glycogenosis type IV: clinical and laboratory findings leading to diagnosis in two siblings. J Inherit Metab Dis. 2004;27(5):609-19. Resumo

68. Kulczycki J, Collinge J, Lojkowska W, et al. Report on the first Polish case of the Gerstmann-Straussler-Scheinker syndrome. Folia Neuropathol. 2001;39(1):27-31. Resumo

69. von Herbay A, Ditton HJ, Schuhmacher F, et al. Whipple's disease: staging and monitoring by cytology and polymerase chain reaction analysis of cerebrospinal fluid. Gastroenterology. 1997 Aug;113(2):434-41. Resumo

70. Ramzan NN, Loftus E Jr, Burgart LJ, et al. Diagnosis and monitoring of Whipple disease by polymerase chain reaction. Ann Intern Med. 1997 Apr 1;126(7):520-7. Resumo

71. Lagier JC, Lepidi H, Raoult D, et al. Systemic Tropheryma whipplei: clinical presentation of 142 patients with infections diagnosed or confirmed in a reference center. Medicine (Baltimore). 2010 Sep;89(5):337-45.Texto completo  Resumo

72. Duss FR, Jaton K, Vollenweider P, et al. Whipple disease: a 15-year retrospective study on 36 patients with positive polymerase chain reaction for Tropheryma whipplei. Clin Microbiol Infect. 2021 Jun;27(6):910.e9-910.e13.Texto completo  Resumo

73. Maizel H, Ruffin JM, Dobbins WO 3rd. Whipple's disease: a review of 19 patients from one hospital and a review of the literature since 1950. Medicine (Baltimore). 1970 May;49(3):175-205.

74. Fleming JL, Wiesner RH, Shorter RG. Whipple's disease: clinical, biochemical, and histopathologic features and assessment of treatment in 29 patients. Mayo Clin Proc. 1988 Jun;63(6):539-51. Resumo

75. von Herbay A, Maiwald M, Ditton HJ, et al. Histology of intestinal Whipple's disease revisited: a study of 48 patients. Virchows Arch. 1996 Dec;429(6):335-43. Resumo

76. Kowalczewska M, Fenollar F, Lafitte D, et al. Identification of candidate antigen in Whipple's disease using a serological proteomic approach. Proteomics. 2006 Jun;6(11):3294-3305. Resumo

77. Boulos A, Rolain JM, Raoult D. Antibiotic susceptibility of Tropheryma whipplei in MRC5 cells. Antimicrob Agents Chemother. 2004 Mar;48(3):747-52.Texto completo  Resumo

78. Boulos A, Rolain JM, Mallet MN, et al. Molecular evaluation of antibiotic susceptibility of Tropheryma whipplei in axenic medium. J Antimicrob Chemother. 2005 Feb;55(2):178-81.Texto completo  Resumo

79. Feurle GE, Junga NS, Marth T. Efficacy of ceftriaxone or meropenem as initial therapies in Whipple's disease. Gastroenterology. 2010 Feb;138(2):478-86; quiz 11-2.Texto completo  Resumo

80. Feurle GE, Moos V, Bläker H, et al. Intravenous ceftriaxone, followed by 12 or three months of oral treatment with trimethoprim-sulfamethoxazole in Whipple's disease. J Infect. 2013 Mar;66(3):263-70. Resumo

81. Lagier JC, Fenollar F, Lepidi H, et al. Treatment of classic Whipple's disease: from in vitro results to clinical outcome. J Antimicrob Chemother. 2014 Jan;69(1):219-27. Resumo

82. Schiepatti A, Nicolardi ML, Marone P, et al. Long-term morbidity and mortality in Whipple's disease: a single-center experience over 20 years. Future Microbiol. 2020 Jul;15:847-54. Resumo

83. Fenollar F, Rolain JM, Alric L, et al. Resistance to trimethoprim/sulfamethoxazole and Tropheryma whipplei. Int J Antimicrob Agents. 2009 Sep;34(3):255-9. Resumo

84. Lagier JC, Fenollar F, Lepidi H, et al. Failure and relapse after treatment with trimethoprim/sulfamethoxazole in classic Whipple's disease. J Antimicrob Chemother. 2010 Sep;65(9):2005-12. Resumo

85. Marumganti AR, Murphy TF. Whipple's disease: neurological relapse presenting as headache for two years. J Gen Intern Med. 2008 Dec;23(12):2131-3. Resumo

86. Garas G, Cheng WS, Abrugiato R, et al. Clinical relapse in Whipple's disease despite maintenance therapy. J Gastroenterol Hepatol. 2000 Oct;15(10):1223-6. Resumo

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