Estado de mal epiléptico

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National Institute for Health and Care Excellence. Epilepsies in children, young people and adults. Apr 2022 [internet publication].Texto completo

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45. Wheless JW, Clarke DF, Arzimanoglou A, et al. Treatment of pediatric epilepsy: European expert opinion, 2007. Epileptic Disord. 2007 Dec;9(4):353-412. Resumo

46. Gaínza-Lein M, Sánchez Fernández I, Jackson M, et al. Association of time to treatment with short-term outcomes for pediatric patients with refractory convulsive status epilepticus. JAMA Neurol. 2018 Apr 1;75(4):410-8.Texto completo  Resumo

47. Osorio I, Reed RC. Treatment of refractory generalized tonic-clonic status epilepticus with pentobarbital anesthesia after high-dose phenytoin. Epilepsia. 1989 Jul-Aug;30(4):464-71. Resumo

48. Kapur J, Elm J, Chamberlain JM, et al. Randomized trial of three anticonvulsant medications for status epilepticus. N Engl J Med. 2019 Nov 28;381(22):2103-13.Texto completo  Resumo

49. Chamberlain JM, Kapur J, Shinnar S, et al. Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised controlled trial. Lancet. 2020 Apr 11;395(10231):1217-24.Texto completo  Resumo

50. Lyttle MD, Rainford NEA, Gamble C, et al. Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial. Lancet. 2019 May 25;393(10186):2125-34.Texto completo  Resumo

51. Dalziel SR, Borland ML, Furyk J, et al. Levetiracetam versus phenytoin for second-line treatment of convulsive status epilepticus in children (ConSEPT): an open-label, multicentre, randomised controlled trial. Lancet. 2019 May 25;393(10186):2135-45. Resumo

52. Trinka E, Höfler J, Leitinger M, et al. Pharmacotherapy for status epilepticus. Drugs. 2015 Sep;75(13):1499-521.Texto completo  Resumo

53. Vasile B, Rasulo F, Candiani A, et al. The pathophysiology of propofol infusion syndrome: a simple name for a complex syndrome. Intensive Care Med. 2003 Sep;29(9):1417-25. Resumo

54. Parviainen I, Uusaro A, Kalviainen R, et al. High-dose thiopental in the treatment of refractory status epilepticus in intensive care unit. Neurology. 2002 Oct 22;59(8):1249-51. Resumo

55. Shorvon S, Ferlisi M. The treatment of super-refractory status epilepticus: a critical review of available therapies and a clinical treatment protocol. Brain. 2011 Oct;134(pt 10):2802-18.Texto completo  Resumo

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58. Pack AM, Oskoui M, Williams Roberson S, et al. Teratogenesis, perinatal, and neurodevelopmental outcomes after in utero exposure to antiseizure medication: practice guideline from the AAN, AES, and SMFM. Neurology. 2024 Jun;102(11):e209279.Texto completo  Resumo

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60. Bromley R, Adab N, Bluett-Duncan M, et al. Monotherapy treatment of epilepsy in pregnancy: congenital malformation outcomes in the child. Cochrane Database Syst Rev. 2023 Aug 29;8(8):CD010224.Texto completo  Resumo

61. Towne AR, Garnett LK, Waterhouse EJ, et al. The use of topiramate in refractory status epilepticus. Neurology. 2003 Jan 28;60(2):332-4. Resumo

62. Welling LC, Rabelo NN, Yoshikawa MH, et al. Efficacy of topiramate as an add-on therapy in patients with refractory status epilepticus: a short systematic review. [in por]. Rev Bras Ter Intensiva. 2021 Oct 25;33(3):440-4.Texto completo  Resumo

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64. Pieribone VA, Tsai J, Soufflet C, et al. Clinical evaluation of ganaxolone in pediatric and adolescent patients with refractory epilepsy. Epilepsia. 2007 Oct;48(10):1870-4.Texto completo  Resumo

65. Vaitkevicius H, Ramsay RE, Swisher CB, et al. Intravenous ganaxolone for the treatment of refractory status epilepticus: results from an open-label, dose-finding, phase 2 trial. Epilepsia. 2022 Sep;63(9):2381-91.Texto completo  Resumo

66. Rosenthal ES, Claassen J, Wainwright MS, et al. Brexanolone as adjunctive therapy in super-refractory status epilepticus. Ann Neurol. 2017 Sep;82(3):342-52.Texto completo  Resumo

67. Alkhachroum A, Der-Nigoghossian CA, Mathews E, et al. Ketamine to treat super-refractory status epilepticus. Neurology. 2020 Oct 20;95(16):e2286-94.Texto completo  Resumo

68. Rosati A, De Masi S, Guerrini R. Ketamine for refractory status epilepticus: a systematic review. CNS Drugs. 2018 Nov;32(11):997-1009. Resumo

69. Thakur KT, Probasco JC, Hocker SE, et al. Ketogenic diet for adults in super-refractory status epilepticus. Neurology. 2014 Feb 25;82(8):665-70.Texto completo  Resumo

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