Carcinoma de células escamosas da pele

Referências

Principais artigos

National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: squamous cell skin cancer [internet publication].Texto completo

Kim JYS, Kozlow JH, Mittal B, et al. Guidelines of care for the management of cutaneous squamous cell carcinoma. J Am Acad Dermatol. 2018 Mar;78(3):560-78.Texto completo  Resumo

Keohane SG, Botting J, Budny PG, et al. British Association of Dermatologists guidelines for the management of people with cutaneous squamous cell carcinoma 2020. Br J Dermatol. 2021 Mar;184(3):401-14.Texto completo  Resumo

Stratigos AJ, Garbe C, Dessinioti C, et al. European consensus-based interdisciplinary guideline for invasive cutaneous squamous cell carcinoma: part 2. Treatment - update 2023. Eur J Cancer. 2023 Nov;193:113252.Texto completo  Resumo

Artigos de referência

1. Weimar VM, Ceilley RI, Goeken JA. Aggressive biologic behavior of basal- and squamous-cell cancers in patients with chronic lymphocytic leukemia or chronic lymphocytic lymphoma. J Dermatol Surg Oncol. 1979 Aug;5(8):609-14. Resumo

2. Schwartz RA. Keratoacanthoma. J Am Acad Dermatol. 1994 Jan;30(1):1-19; quiz 20-2. Resumo

3. Walder BK, Robertson MR, Jeremy D. Skin cancer and immunosuppression. Lancet. 1971 Dec 11;2(7737):1282-3. Resumo

4. Phillips TJ, Salman SM, Bhawan J, et al. Burn scar carcinoma. Diagnosis and management. Dermatol Surg. 1998 May;24(5):561-5. Resumo

5. Sánchez G, Nova J, Rodriguez-Hernandez AE, et al. Sun protection for preventing basal cell and squamous cell skin cancers. Cochrane Database Syst Rev. 2016 Jul 25;(7):CD011161. Resumo

6. Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021 May;71(3):209-49.Texto completo  Resumo

7. Gogia R, Binstock M, Hirose R, et al. Fitzpatrick skin phototype is an independent predictor of squamous cell carcinoma risk after solid organ transplantation. J Am Acad Dermatol. 2013 Apr;68(4):585-91. Resumo

8. Larese Filon F, Buric M, Fluehler C. UV exposure, preventive habits, risk perception, and occupation in NMSC patients: a case-control study in Trieste (NE Italy). Photodermatol Photoimmunol Photomed. 2019 Jan;35(1):24-30. Resumo

9. Laughter MR, Maymone MBC, Karimkhani C, et al. The burden of skin and subcutaneous diseases in the United States from 1990 to 2017. JAMA Dermatol. 2020 Aug 1;156(8):874-81.Texto completo  Resumo

10. Johnson TM, Rowe DE, Nelson BR, et al. Squamous cell carcinoma of the skin (excluding lip and oral mucosa). J Am Acad Dermatol. 1992 Mar;26(3 Pt 2):467-84. Resumo

11. Ibrahim N, Ali SR, Dobbs TD, et al. The incidence of non-melanoma skin cancer in the UK and the Republic of Ireland: a systematic review. Eur J Dermatol. 2023 Jun 1;33(3):218-29. Resumo

12. Massey PR, Schmults CD, Li SJ, et al. Consensus-based recommendations on the prevention of squamous cell carcinoma in solid organ transplant recipients: a Delphi consensus statement. JAMA Dermatol. 2021 Sep 1 [Epub ahead of print]. Resumo

13. Zakhem GA, Pulavarty AN, Lester JC, et al. Skin cancer in people of color: a systematic review. Am J Clin Dermatol. 2022 Mar;23(2):137-51. Resumo

14. Hogue L, Harvey VM. Basal cell carcinoma, squamous cell carcinoma, and cutaneous melanoma in skin of color patients. Dermatol Clin. 2019 Oct;37(4):519-26.Texto completo  Resumo

15. Jin F, Vajdic CM, Poynten IM, et al. Cancer risk in people living with HIV and solid organ transplant recipients: a systematic review and meta-analysis. Lancet Oncol. 2024 Jul;25(7):933-44. Resumo

16. Buettner PG, Raasch BA. Incidence rates of skin cancer in Townsville, Australia. Int J Cancer. 1998 Nov 23;78(5):587-93.Texto completo  Resumo

17. Venables ZC, Autier P, Nijsten T, et al. Nationwide incidence of metastatic cutaneous squamous cell carcinoma in England. JAMA Dermatol. 2019 Mar 1;155(3):298-306.Texto completo  Resumo

18. Miller DL, Weinstock MA. Nonmelanoma skin cancer in the United States: incidence. J Am Acad Dermatol. 1994 May;30(5 pt 1):774-8.Texto completo  Resumo

19. Rogers HW, Weinstock MA, Feldman SR, et al. Incidence estimate of nonmelanoma skin cancer (keratinocyte carcinomas) in the US population, 2012. JAMA Dermatol. 2015 Oct;151(10):1081-6.Texto completo  Resumo

20. Muzic JG, Schmitt AR, Wright AC, et al. Incidence and trends of basal cell carcinoma and cutaneous squamous cell carcinoma: a population-based study in Olmsted County, Minnesota, 2000 to 2010. Mayo Clin Proc. 2017 Jun;92(6):890-8. Resumo

21. Vitaliano PP, Urbach F. The relative importance of risk factors in nonmelanoma carcinoma. Arch Dermatol. 1980 Apr;116(4):454-6. Resumo

22. Kinlen LJ, Sheil AG, Peto J, et al. Collaborative United Kingdom-Australasian study of cancer in patients treated with immunosuppressive drugs. Br Med J. 1979 Dec 8;2(6203):1461-6.Texto completo  Resumo

23. Weistenhöfer W, Lutz R, Hiller J, et al. Syncarcinogenesis of natural UV radiation and polycyclic aromatic hydrocarbons in the development of squamous cell carcinomas of the skin? J Dtsch Dermatol Ges. 2022 Sep;20(9):1179-86.Texto completo  Resumo

24. Namgoong S, Kim J, Jeong KM, et al. Association of human papillomavirus and extra-genital Bowen disease (squamous cell carcinoma in situ): a systematic review. J Am Acad Dermatol. 2021 Mar;84(3):822-5.Texto completo  Resumo

25. Paprottka FJ, Bontikous S, Lohmeyer JA, et al. Squamous-cell carcinoma arises in red parts of multicolored tattoo within months. Plast Reconstr Surg Glob Open. 2014 Apr 7;2(3):e114.Texto completo  Resumo

26. Droll S, Bao X. Oh, the mutations you'll acquire! A systematic overview of cutaneous squamous cell carcinoma. Cell Physiol Biochem. 2021 Sep 22;55(s2):89-119.Texto completo  Resumo

27. Kripke ML. Immunological effects of ultraviolet radiation. J Dermatol. 1991 Aug;18(8):429-33. Resumo

28. de Gruijl FR, van Kranen HJ, Mullenders LH. UV-induced DNA damage, repair, mutations and oncogenic pathways in skin cancer. J Photochem Photobiol B. 2001 Oct;63(1-3):19-27. Resumo

29. Liang SB, Ohtsuki Y, Furihata M, et al. Sun-exposure- and aging-dependent p53 protein accumulation results in growth advantage for tumour cells in carcinogenesis of nonmelanocytic skin cancer. Virchows Arch. 1999 Mar;434(3):193-9. Resumo

30. Ming M, Feng L, Shea CR, et al. PTEN positively regulates UVB-induced DNA damage repair. Cancer Res. 2011 Aug 1;71(15):5287-95. Resumo

31. Ming M, Han W, Maddox J, et al. UVB-induced ERK/AKT-dependent PTEN suppression promotes survival of epidermal keratinocytes. Oncogene. 2010 Jan 28;29(4):492-502.Texto completo  Resumo

32. Tsai KY, Tsao H. The genetics of skin cancer. Am J Med Genet C Semin Med Genet. 2004 Nov 15;131C(1):82-92. Resumo

33. Han W, Ming M, He TC, et al. Immunosuppressive cyclosporin A activates AKT in keratinocytes through PTEN suppression: implications in skin carcinogenesis. J Biol Chem. 2010 Apr 9;285(15):11369-77.Texto completo  Resumo

34. Han W, Soltani K, Ming M, et al. Deregulation of XPC and CypA by cyclosporin A: an immunosuppression-independent mechanism of skin carcinogenesis. Cancer Prev Res (Phila). 2012 Sep;5(9):1155-62. Resumo

35. Kanitz A, Imig J, Dziunycz PJ, et al. The expression levels of microRNA-361-5p and its target VEGFA are inversely correlated in human cutaneous squamous cell carcinoma. PLoS One. 2012;7(11):e49568.Texto completo  Resumo

36. Hu SC, Yu HS, Yen FL, et al. CXCR7 expression correlates with tumor depth in cutaneous squamous cell carcinoma skin lesions and promotes tumor cell survival through ERK activation. Exp Dermatol. 2014 Dec;23(12):902-8. Resumo

37. Dong F, Wang Y, Li L, et al. CD109 expression is increased in cutaneous squamous cell carcinoma. J Dermatol. 2014 Oct;41(10):947-9. Resumo

38. Lee CS, Bhaduri A, Mah A, et al. Recurrent point mutations in the kinetochore gene KNSTRN in cutaneous squamous cell carcinoma. Nat Genet. 2014 Oct;46(10):1060-2. Resumo

39. Kuźbicki Ł, Brożyna AA. Expression of cyclooxygenase-2 in human epithelial skin lesions: a systematic review of immunohistochemical studies. Appl Immunohistochem Mol Morphol. 2021 Mar 1;29(3):163-74. Resumo

40. Fears TR, Scotto J. Estimating increases in skin cancer morbidity due to increases in ultraviolet radiation exposure. Cancer Invest. 1983;1(2):119-26. Resumo

41. Rundel RD. Promotional effects of ultraviolet radiation on human basal and squamous cell carcinoma. Photochem Photobiol. 1983 Nov;38(5):569-75. Resumo

42. Glover MT, Deeks JJ, Raftery MJ, et al. Immunosuppression and risk of non-melanoma skin cancer in renal transplant recipients. Lancet. 1997 Feb 8;349(9049):398. Resumo

43. Hofbauer GF, Anliker M, Arnold A, et al. Swiss clinical practice guidelines for skin cancer in organ transplant recipients. Swiss Med Wkly. 2009 Jul 25;139(29-30):407-15. Resumo

44. Bibee K, Swartz A, Sridharan S, et al. Cutaneous squamous cell carcinoma in the organ transplant recipient. Oral Oncol. 2020 Apr;103:104562. Resumo

45. Preciado DA, Matas A, Adams GL. Squamous cell carcinoma of the head and neck in solid organ transplant recipients. Head Neck. 2002 Apr;24(4):319-25. Resumo

46. Mattei PL, Alora-Palli MB, Kraft S, et al. Cutaneous effects of BRAF inhibitor therapy: a case series. Ann Oncol. 2013 Feb;24(2):530-7. Resumo

47. Belum VR, Rosen AC, Jaimes N, et al. Clinico-morphological features of BRAF inhibition-induced proliferative skin lesions in cancer patients. Cancer. 2015 Jan 1;121(1):60-8.Texto completo  Resumo

48. Keeler CE. Albinism, xeroderma pigmentosum, and skin cancer. Natl Cancer Inst Monogr. 1963;10:349-59.

49. Kraemer KH, Lee MM, Scotto J. Xeroderma pigmentosum: cutaneous, ocular, and neurologic abnormalities in 830 published cases. Arch Dermatol. 1987 Feb;123(2):241-50. Resumo

50. Yarbro JW, Page DL, Fielding LP, et al. American Joint Committee on Cancer prognostic factors consensus conference. Cancer. 1999 Dec 1;86(11):2436-46. Resumo

51. Wagner SL, Maliner JS, Morton WE, et al. Skin cancer and arsenical intoxication from well water. Arch Dermatol. 1979 Oct;115(10):1205-7. Resumo

52. Wong ST, Chan HL, Teo SK. The spectrum of cutaneous and internal malignancies in chronic arsenic toxicity. Singapore Med J. 1998 Apr;39(4):171-3. Resumo

53. Glogau RG. The risk of progression to invasive disease. J Am Acad Dermatol. 2000 Jan;42(1 Pt 2):23-4. Resumo

54. Ahmady S, Jansen MHE, Nelemans PJ, et al. Risk of invasive cutaneous squamous cell carcinoma after different treatments for actinic keratosis: a secondary analysis of a randomized clinical trial. JAMA Dermatol. 2022 Jun 1;158(6):634-40. Resumo

55. Sun H, Li Y, Zeng F, et al. Melanoma survivors are at increased risk for second primary keratinocyte carcinoma. Int J Dermatol. 2022 Nov;61(11):1397-404. Resumo

56. Lichter MD, Karagas MR, Mott LA, et al; The New Hampshire Skin Cancer Study Group. Therapeutic ionizing radiation and the incidence of basal cell carcinoma and squamous cell carcinoma. Arch Dermatol. 2000 Aug;136(8):1007-11.Texto completo  Resumo

57. Harwood CA, Surentheran T, McGregor JM, et al. Human papillomavirus infection and non-melanoma skin cancer in immunosuppressed and immunocompetent individuals. J Med Virol. 2000 Jul;61(3):289-97. Resumo

58. Meyer T, Arndt R, Christophers E, et al. Importance of human papillomaviruses for the development of skin cancer. Cancer Detect Prev. 2001;25(6):533-47. Resumo

59. de Villiers EM, Lavergne D, McLaren K, et al. Prevailing papillomavirus types in non-melanoma carcinomas of the skin in renal allograft recipients. Int J Cancer. 1997 Nov 4;73(3):356-61. Resumo

60. Viac J, Chardonnet Y, Chignol MC, et al. Papilloma viruses, warts, carcinoma and Langerhans cells. In Vivo. 1993 May-Jun;7(3):207-12. Resumo

61. Leonardi-Bee J, Ellison T, Bath-Hextall F. Smoking and the risk of nonmelanoma skin cancer: systematic review and meta-analysis. Arch Dermatol. 2012 Aug;148(8):939-46. Resumo

62. Song F, Qureshi AA, Gao X, et al. Smoking and risk of skin cancer: a prospective analysis and a meta-analysis. Int J Epidemiol. 2012 Dec;41(6):1694-705. Resumo

63. Traianou A, Ulrich M, Apalla Z,et al; EPIDERM Group. Risk factors for actinic keratosis in eight European centres: a case-control study. Br J Dermatol. 2012 Aug;167 Suppl 2:36-42. Resumo

64. Shao SC, Lai CC, Chen YH, et al. Associations of thiazide use with skin cancers: a systematic review and meta-analysis. BMC Med. 2022 Jul 7;20(1):228.Texto completo  Resumo

65. de Macedo Andrade AC, Felix FA, França GM, et al. Hydrochlorothiazide use is associated with the risk of cutaneous and lip squamous cell carcinoma: a systematic review and meta-analysis. Eur J Clin Pharmacol. 2022 Jun;78(6):919-30. Resumo

66. Kluger N, Koljonen V. Tattoos, inks, and cancer. Lancet Oncol. 2012 Apr;13(4):e161-8. Resumo

67. US Preventive Services Task Force, Grossman DC, Curry SJ, et al. Behavioral counseling to prevent skin cancer: US Preventive Services Task Force recommendation statement. JAMA. 2018 Mar 20;319(11):1134-42.Texto completo  Resumo

68. Farmer KC, Naylor MF. Sun exposure, sunscreens, and skin cancer prevention: a year-round concern. Ann Pharmacother. 1996 Jun;30(6):662-73. Resumo

69. Gordon LG, Scuffham PA, van der Pols JC, et al. Regular sunscreen use is a cost-effective approach to skin cancer prevention in subtropical settings. J Invest Dermatol. 2009 Dec;129(12):2766-71.Texto completo  Resumo

70. Hirst NG, Gordon LG, Scuffham PA, et al. Lifetime cost-effectiveness of skin cancer prevention through promotion of daily sunscreen use. Value Health. 2012 Mar-Apr;15(2):261-8. Resumo

71. Rönsch H, Bauer A. The preventive value of sun protection. Curr Probl Dermatol. 2021;55:316-28. Resumo

72. Green A, Williams G, Neale R, et al. Daily sunscreen application and betacarotene supplementation in prevention of basal-cell and squamous-cell carcinoma of the skin: a randomised controlled trial. Lancet. 1999 Aug 28;354(9180):723-9. Resumo

73. Thompson SC, Jolley D, Marks R. Reduction of solar keratoses by regular sunscreen use. N Engl J Med. 1993 Oct 14;329(16):1147-51.Texto completo  Resumo

74. Darlington S, Williams G, Neale R, et al. A randomized controlled trial to assess sunscreen application and beta carotene supplementation in the prevention of solar keratoses. Arch Dermatol. 2003 Apr;139(4):451-5.Texto completo  Resumo

75. National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: squamous cell skin cancer [internet publication].Texto completo

76. Abdi MA, Yan M, Hanna TP. Systematic review of modern case series of squamous cell cancer arising in a chronic ulcer (Marjolin's ulcer) of the skin. JCO Glob Oncol. 2020 Jun;6:809-18.Texto completo  Resumo

77. Libson K, Sheridan C, Carr DR, et al. Use of imaging in cutaneous squamous cell carcinoma to detect high-risk tumor features, nodal metastasis, and distant metastasis: a systematic review. Dermatol Surg. 2024 Aug 1;50(8):705-9. Resumo

78. Barr RJ. Classification of cutaneous squamous cell carcinoma. J Cutan Pathol. 1991 Aug;18(4):225-6. Resumo

79. Cassarino DS, Derienzo DP, Barr RJ. Cutaneous squamous cell carcinoma: a comprehensive clinicopathologic classification. Part one. J Cutan Pathol. 2006 Mar;33(3):191-206. Resumo

80. Broders AC. Squamous-cell epithelioma of the skin: a study of 256 cases. Ann Surg. 1921 Feb;73(2):141-60.Texto completo  Resumo

81. Amin MB, Edge S, Greene F, et al. (eds); American Joint Committee on Cancer. AJCC cancer staging manual. 8th ed. New York, NY: Springer; 2017.

82. Schmults CD, Karia PS, Carter JB, et al. Factors predictive of recurrence and death from cutaneous squamous cell carcinoma: a 10-year, single-institution cohort study. JAMA Dermatol. 2013 May;149(5):541-7.Texto completo  Resumo

83. Karia PS, Jambusaria-Pahlajani A, Harrington DP, et al. Evaluation of American Joint Committee on Cancer, International Union Against Cancer, and Brigham and Women's Hospital tumor staging for cutaneous squamous cell carcinoma. J Clin Oncol. 2014 Feb 1;32(4):327-34. Resumo

84. US Preventive Services Task Force, Mangione CM, Barry MJ, et al. Screening for skin cancer: US Preventive Services Task Force recommendation statement. JAMA. 2023 Apr 18;329(15):1290-5.Texto completo  Resumo

85. Kim JYS, Kozlow JH, Mittal B, et al. Guidelines of care for the management of cutaneous squamous cell carcinoma. J Am Acad Dermatol. 2018 Mar;78(3):560-78.Texto completo  Resumo

86. Mittal A, Colegio OR. Skin cancers in organ transplant recipients. Am J Transplant. 2017 Oct;17(10):2509-30.Texto completo  Resumo

87. Keohane SG, Botting J, Budny PG, et al. British Association of Dermatologists guidelines for the management of people with cutaneous squamous cell carcinoma 2020. Br J Dermatol. 2021 Mar;184(3):401-14.Texto completo  Resumo

88. Behshad R, Garcia-Zuazaga J, Bordeaux JS. Systemic treatment of locally advanced nonmetastatic cutaneous squamous cell carcinoma: a review of the literature. Br J Dermatol. 2011 Dec;165(6):1169-77. Resumo

89. Shimizu I, Cruz A, Chang KH, et al. Treatment of squamous cell carcinoma in situ: a review. Dermatol Surg. 2011 Oct;37(10):1394-411. Resumo

90. Bath-Hextall FJ, Matin RN, Wilkinson D, et al. Interventions for cutaneous Bowen's disease. Cochrane Database Syst Rev. 2013 Jun 24;(6):CD007281.Texto completo  Resumo

91. Stewart JR, Lang ME, Brewer JD. Efficacy of nonexcisional treatment modalities for superficially invasive and in situ squamous cell carcinoma: a systematic review and meta-analysis. J Am Acad Dermatol. 2022 Jul;87(1):131-7. Resumo

92. Goette DK. Topical chemotherapy with 5-fluorouracil. A review. J Am Acad Dermatol. 1981 Jun;4(6):633-49. Resumo

93. Kaur RR, Alikhan A, Maibach HI. Comparison of topical 5-fluorouracil formulations in actinic keratosis treatment. J Dermatolog Treat. 2010 Sep;21(5):267-71. Resumo

94. Feldman SR, Fleischer AB Jr, Williford PM, et al. Destructive procedures are the standard of care for treatment of actinic keratoses. J Am Acad Dermatol. 1999 Jan;40(1):43-7. Resumo

95. Kuflik EG, Gage AA. The five-year cure rate achieved by cryosurgery for skin cancer. J Am Acad Dermatol. 1991 Jun;24(6 Pt 1):1002-4. Resumo

96. Williamson GS, Jackson R. Treatment of squamous cell carcinoma of the skin by electrodesiccation and curettage. Can Med Assoc J. 1964 Feb 8;90:408-13.Texto completo  Resumo

97. Rosenthal A, Juhasz MLW, Chang C, et al. Lasers for the treatment of nonmelanoma skin cancer: a systematic review of the literature. Dermatol Surg. 2024 Aug 1;50(8):714-9. Resumo

98. Wong TH, Morton CA, Collier N, et al. British Association of Dermatologists and British Photodermatology Group guidelines for topical photodynamic therapy 2018. Br J Dermatol. 2019 Apr;180(4):730-9.Texto completo  Resumo

99. Xue WL, Ruan JQ, Liu HY, et al. Efficacy of photodynamic therapy for the treatment of Bowen's disease: a meta-analysis of randomized controlled trials. Dermatology. 2022;238(3):542-50.Texto completo  Resumo

100. Antonetti P, Pellegrini C, Caponio C, et al. Photodynamic therapy for the treatment of Bowen's disease: a review on efficacy, non-invasive treatment monitoring, tolerability, and cosmetic outcome. Biomedicines. 2024 Apr 3;12(4):795.Texto completo  Resumo

101. Zygogianni A, Kouvaris J, Tolia M, et al. The potential role of radiation therapy in Bowen's disease: a review of the current literature. Rev Recent Clin Trials. 2012 Feb;7(1):42-6.Texto completo  Resumo

102. Brodland DG, Zitelli JA. Surgical margins for excision of primary cutaneous squamous cell carcinoma. J Am Acad Dermatol. 1992 Aug;27(2 Pt 1):241-8. Resumo

103. Lambert DR, Siegle RJ. Skin cancer: a review with consideration of treatment options including Mohs micrographic surgery. Ohio Med. 1990 Oct;86(10):745-7. Resumo

104. Robinson JK. Mohs micrographic surgery. Clin Plast Surg. 1993 Jan;20(1):149-56. Resumo

105. Boettler MA, Gray AN, Brodsky MA, et al. Mohs micrographic surgery for verrucous carcinoma: a review of the literature. Arch Dermatol Res. 2023 Mar;315(2):133-7. Resumo

106. Connolly SM, Baker DR, Coldiron BM, et al; Ad Hoc Task Force. AAD/ACMS/ASDSA/ASMS 2012 appropriate use criteria for Mohs micrographic surgery: a report of the American Academy of Dermatology, American College of Mohs Surgery, American Society for Dermatologic Surgery Association, and the American Society for Mohs Surgery. Dermatol Surg. 2012 Oct;38(10):1582-603. Resumo

107. Emmett AJ, Broadbent GD. Shave excision of superficial solar skin lesions. Plast Reconstr Surg. 1987 Jul;80(1):47-54. Resumo

108. Veness MJ. Treatment recommendations in patients diagnosed with high-risk cutaneous squamous cell carcinoma. Australas Radiol. 2005 Oct;49(5):365-76. Resumo

109. Martinez JC, Otley CC, Okuno SH, et al. Chemotherapy in the management of advanced cutaneous squamous cell carcinoma in organ transplant recipients: theoretical and practical considerations. Dermatol Surg. 2004 Apr;30(4 Pt 2):679-86. Resumo

110. Gross ND, Miller DM, Khushalani NI, et al. Neoadjuvant cemiplimab for stage II to IV cutaneous squamous-cell carcinoma. N Engl J Med. 2022 Oct 27;387(17):1557-68.Texto completo  Resumo

111. Migden MR, Khushalani NI, Chang ALS, et al. Cemiplimab in locally advanced cutaneous squamous cell carcinoma: results from an open-label, phase 2, single-arm trial. Lancet Oncol. 2020 Feb;21(2):294-305. Resumo

112. Gross ND, Miller DM, Khushalani NI, et al. Neoadjuvant cemiplimab and surgery for stage II-IV cutaneous squamous-cell carcinoma: follow-up and survival outcomes of a single-arm, multicentre, phase 2 study. Lancet Oncol. 2023 Nov;24(11):1196-1205. Resumo

113. Stratigos AJ, Garbe C, Dessinioti C, et al. European consensus-based interdisciplinary guideline for invasive cutaneous squamous cell carcinoma: part 2. Treatment - update 2023. Eur J Cancer. 2023 Nov;193:113252.Texto completo  Resumo

114. National Institute of Health and Care Excellence. Cemiplimab for treating advanced cutaneous squamous cell carcinoma. Jun 2022 [internet publication].Texto completo

115. Cañueto J, Muñoz-Couselo E, Cardona-Machado C, et al. Efficacy and safety of cemiplimab in the treatment of advanced cutaneous squamous cell carcinoma: a multicentre real-world retrospective study from Spain and systematic review of the published data. J Eur Acad Dermatol Venereol. 2024 Aug;38(8):e666-70. Resumo

116. Young NR, Liu J, Pierce C, et al. Molecular phenotype predicts sensitivity of squamous cell carcinoma of the head and neck to epidermal growth factor receptor inhibition. Mol Oncol. 2013 Jun;7(3):359-68. Resumo

117. Markovic A, Chung CH. Current role of EGF receptor monoclonal antibodies and tyrosine kinase inhibitors in the management of head and neck squamous cell carcinoma. Expert Rev Anticancer Ther. 2012 Sep;12(9):1149-59. Resumo

118. Pham JP, Rodrigues A, Goldinger SM, et al. Epidermal growth factor receptor inhibitors in advanced cutaneous squamous cell carcinoma: a systematic review and meta-analysis. Exp Dermatol. 2024 Jan;33(1):e14978.Texto completo  Resumo

119. Zhang J, Wang Y, Wijaya WA, et al. Efficacy and prognostic factors of adjuvant radiotherapy for cutaneous squamous cell carcinoma: a systematic review and meta-analysis. J Eur Acad Dermatol Venereol. 2021 Sep;35(9):1777-87.Texto completo  Resumo

120. Daniels CP, Liu HY, Porceddu SV. Indications and limits of postoperative radiotherapy for skin malignancies. Curr Opin Otolaryngol Head Neck Surg. 2021 Apr 1;29(2):100-6. Resumo

121. Niles RM. Recent advances in the use of vitamin A (retinoids) in the prevention and treatment of cancer. Nutrition. 2000 Nov-Dec;16(11-12):1084-9. Resumo

122. Jambusaria-Pahlajani A, Miller CJ, Quon H, et al. Surgical monotherapy versus surgery plus adjuvant radiotherapy in high-risk cutaneous squamous cell carcinoma: a systematic review of outcomes. Dermatol Surg. 2009 Apr;35(4):574-85. Resumo

123. Han A, Ratner D. What is the role of adjuvant radiotherapy in the treatment of cutaneous squamous cell carcinoma with perineural invasion? Cancer. 2007 Mar 15;109(6):1053-9. Resumo

124. Chen AC, Martin AJ, Choy B, et al. A phase 3 randomized trial of nicotinamide for skin-cancer chemoprevention. N Engl J Med. 2015 Oct 22;373(17):1618-26.Texto completo  Resumo

125. Mainville L, Smilga AS, Fortin PR. Effect of nicotinamide in skin cancer and actinic keratoses chemoprophylaxis, and adverse effects related to nicotinamide: a systematic review and meta-analysis. J Cutan Med Surg. 2022 May-Jun;26(3):297-308.Texto completo  Resumo

126. Tosti G, Pepe F, Gnagnarella P, et al. The role of nicotinamide as chemo-preventive agent in NMSCs: a systematic review and meta-analysis. Nutrients. 2023 Dec 27;16(1):100.Texto completo  Resumo

127. Marcil I, Stern RS. Risk of developing a subsequent nonmelanoma skin cancer in patients with a history of nonmelanoma skin cancer: a critical review of the literature and meta-analysis. Arch Dermatol. 2000 Dec;136(12):1524-30. Resumo

128. Zakhem GA, Pulavarty AN, Carucci J, et al. Association of patient risk factors, tumor characteristics, and treatment modality with poor outcomes in primary cutaneous squamous cell carcinoma: a systematic review and meta-analysis. JAMA Dermatol. 2023 Feb 1;159(2):160-171.Texto completo  Resumo

129. Russell E, Udkoff J, Knackstedt T. Squamous cell carcinoma with bone invasion: a systematic review and pooled survival analysis. Dermatol Surg. 2022 Oct 1;48(10):1025-8. Resumo

130. Mulvaney PM, Massey PR, Yu KK, et al. Differential molecular expression patterns associated with metastasis in cutaneous squamous cell carcinoma: a systematic review and meta-analysis. J Invest Dermatol. 2021 Sep;141(9):2161-9.Texto completo  Resumo

131. Epstein E, Epstein NN, Bragg K, et al. Metastases from squamous cell carcinoma of the skin. Arch Dermatol. 1968 Mar;97(3):245-51. Resumo

132. Jones TP, Boiko PE, Piepkorn MW. Skin biopsy indications in primary care practice: a population-based study. J Am Board Fam Pract. 1996 Nov-Dec;9(6):397-404. Resumo

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