Referências
Principais artigos
American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 5th ed., text revision (DSM-5-TR). Washington, DC: American Psychiatric Publishing; 2022.Texto completo
Sateia MJ, Buysse DJ, Krystal AD, et al. Clinical practice guideline for the pharmacologic treatment of chronic insomnia in adults: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2017 Feb 15;13(2):307-49.Texto completo Resumo
Qaseem A, Kansagara D, Forciea MA, et al. Management of chronic insomnia disorder in adults: a clinical practice guideline from the American College of Physicians. Ann Intern Med. 2016 Jul 19;165(2):125-33.Texto completo Resumo
Edinger JD, Arnedt JT, Bertisch SM, et al. Behavioral and psychological treatments for chronic insomnia disorder in adults: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2021 Feb 1;17(2):255-62.Texto completo Resumo
Artigos de referência
1. American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 5th ed., text revision (DSM-5-TR). Washington, DC: American Psychiatric Publishing; 2022.Texto completo
2. American Academy of Sleep Medicine. The AASM international classification of sleep disorders - third edition, text revision (ICSD-3-TR). Jun 2023 [internet publication].Texto completo
3. Vargas I, Nguyen AM, Muench A, et al. Acute and chronic insomnia: what has time and/or hyperarousal got to do with It? Brain Sci. 2020 Jan 29;10(2):71.Texto completo Resumo
4. Yang L, Zhang J, Luo X, et al. Effectiveness of one-week internet-delivered cognitive behavioral therapy for insomnia to prevent progression from acute to chronic insomnia: a two-arm, multi-center, randomized controlled trial. Psychiatry Res. 2023 Mar;321:115066. Resumo
5. Ellis JG, Cushing T, Germain A. Treating acute insomnia: a randomized controlled trial of a "single-shot" of cognitive behavioral therapy for insomnia. Sleep. 2015 Jun 1;38(6):971-8.Texto completo Resumo
6. Randall C, Nowakowski S, Ellis JG. Managing acute insomnia in prison: evaluation of a "one-shot" cognitive behavioral therapy for insomnia (CBT-I) intervention. Behav Sleep Med. 2019 Nov-Dec;17(6):827-36.Texto completo Resumo
7. Perlis ML, Posner D, Riemann D, et al. Insomnia. Lancet. 2022 Sep 24;400(10357):1047-60. Resumo
8. Ohayon MM. Epidemiology of insomnia: what we know and what we still need to learn. Sleep Med Rev. 2002 Apr;6(2):97-111. Resumo
9. National Institutes of Health. National Institutes of Health State of the Science Conference statement on manifestations and management of chronic insomnia in adults, June 13-15, 2005. Sleep. 2005 Sep;28(9):1049-57. Resumo
10. Morin CM, LeBlanc M, Bélanger L, et al. Prevalence of insomnia and its treatment in Canada. Can J Psychiatry. 2011 Sep;56(9):540-8.Texto completo Resumo
11. Wickwire EM, Shaya FT, Scharf SM. Health economics of insomnia treatments: the return on investment for a good night's sleep. Sleep Med Rev. 2016 Dec;30:72-82. Resumo
12. Cochen V, Arbus C, Soto ME, et al. Sleep disorders and their impacts on healthy, dependent, and frail older adults. J Nutr Health Aging. 2009 Apr;13(4):322-9. Resumo
13. Benca RM, Ancoli-Israel S, Moldofsky H. Special considerations in insomnia diagnosis and management: depressed, elderly, and chronic pain populations. J Clin Psychiatry. 2004;65(suppl 8):26-35. Resumo
14. Smagula SF, Stone KL, Fabio A, et al. Risk factors for sleep disturbances in older adults: evidence from prospective studies. Sleep Med Rev. 2016 Feb;25:21-30.Texto completo Resumo
15. Breslau N, Roth T, Rosenthal L, et al. Sleep disturbance and psychiatric disorders: a longitudinal epidemiological study of young adults. Biol Psychiatry. 1996 Mar 15;39(6):411-8. Resumo
16. Mellinger GD, Balter MB, Uhlenhuth EH. Insomnia and its treatment: prevalence and correlates. Arch Gen Psychiatry. 1985 Mar;42(3):225-32. Resumo
17. Lindberg E, Janson C, Gislason T, et al. Sleep disturbances in a young adult population: can gender differences be explained by differences in psychological status? Sleep. 1997 Jun;20(6):381-7. Resumo
18. Roth T. Insomnia: definition, prevalence, etiology, and consequences. J Clin Sleep Med. 2007 Aug 15;3(5 suppl):S7-10.Texto completo Resumo
19. Harvey AG. A cognitive model of insomnia. Behav Res Ther. 2002 Aug;40(8):869-93. Resumo
20. Spielman AJ, Caruso LS, Glovinsky PB. A behavioral perspective on insomnia treatment. Psychiatr Clin North Am. 1987 Dec;10(4):541-53. Resumo
21. Reeve S, Sheaves B, Freeman D. The role of sleep dysfunction in the occurrence of delusions and hallucinations: a systematic review. Clin Psychol Rev. 2015 Dec;42:96-115.Texto completo Resumo
22. Gates P, Albertella L, Copeland J. Cannabis withdrawal and sleep: a systematic review of human studies. Subst Abus. 2016;37(1):255-69. Resumo
23. Perney P, Lehert P. Insomnia in alcohol-dependent patients: prevalence, risk factors and acamprosate effect: an individual patient data meta-analysis. Alcohol Alcohol. 2018 Sep 1;53(5):611-8. Resumo
24. Ford DE, Kamerow DB. Epidemiologic study of sleep disturbances and psychiatric disorders: an opportunity for prevention? JAMA. 1989 Sep 15;262(11):1479-84. Resumo
25. Pigeon WR, Bishop TM, Krueger KM. Insomnia as a precipitating factor in new onset mental illness: a systematic review of recent findings. Curr Psychiatry Rep. 2017 Aug;19(8):44. Resumo
26. Nierenberg AA, Pava JA, Clancy K, et al. Are neurovegetative symptoms stable in relapsing or recurrent atypical depressive episodes? Biol Psychiatry. 1996 Oct 15;40(8):691-6. Resumo
27. Li L, Wu C, Gan Y, et al. Insomnia and the risk of depression: a meta-analysis of prospective cohort studies. BMC Psychiatry. 2016 Nov 5;16(1):375.Texto completo Resumo
28. Baglioni C, Battagliese G, Feige B, et al. Insomnia as a predictor of depression: a meta-analytic evaluation of longitudinal epidemiological studies. J Affect Disord. 2011 Dec;135(1-3):10-9. Resumo
29. Irwin MR, Carrillo C, Sadeghi N, et al. Prevention of incident and recurrent major depression in older adults with insomnia: a randomized clinical trial. JAMA Psychiatry. 2022 Jan 1;79(1):33-41.Texto completo Resumo
30. Krystal AD, Thase ME, Tucker VL, et al. Bupropion HCL and sleep in patients with depression. Curr Psych Rev. 2007;3(2):123-8.Texto completo
31. Doufas AG, Panagiotou OA, Panousis P, et al. Insomnia from drug treatments: evidence from meta-analyses of randomized trials and concordance with prescribing information. Mayo Clin Proc. 2017 Jan;92(1):72-87. Resumo
32. Ancoli-Israel S, Roth T. Characteristics of insomnia in the United States: results of the 1991 National Sleep Foundation Survey. I. Sleep. 1999 May 1;22(suppl 2):S347-53. Resumo
33. Ohayon MM, Roth T. What are the contributing factors for insomnia in the general population? J Psychosom Res. 2001 Dec;51(6):745-55. Resumo
34. Katz DA, McHorney CA. Clinical correlates of insomnia in patients with chronic illness. Arch Intern Med. 1998 May 25;158(10):1099-107.Texto completo Resumo
35. Mallon L, Broman JE, Hetta J. Sleep complaints predict coronary artery disease mortality in males: a 12-year follow-up study of a middle-aged Swedish population. J Intern Med. 2002 Mar;251(3):207-16.Texto completo Resumo
36. McCracken LM, Iverson GL. Disrupted sleep patterns and daily functioning in patients with chronic pain. Pain Res Manag. 2002 Summer;7(2):75-9. Resumo
37. Mathias JL, Cant ML, Burke ALJ. Sleep disturbances and sleep disorders in adults living with chronic pain: a meta-analysis. Sleep Med. 2018 Dec;52:198-210. Resumo
38. Nicassio PM, Wallston KA. Longitudinal relationships among pain, sleep problems, and depression in rheumatoid arthritis. J Abnorm Psychol. 1992 Aug;101(3):514-20. Resumo
39. Dressle RJ, Riemann D. Hyperarousal in insomnia disorder: current evidence and potential mechanisms. J Sleep Res. 2023 Dec;32(6):e13928.Texto completo Resumo
40. Levenson JC, Kay DB, Buysse DJ. The pathophysiology of insomnia. Chest. 2015 Apr;147(4):1179-92.Texto completo Resumo
41. Bonnet MH, Arand DL. 24-hour metabolic rate in insomniacs and matched normal sleepers. Sleep. 1995 Sep;18(7):581-8. Resumo
42. Bonnet MH, Arand DL. Physiological activation in patients with sleep state misperception. Psychosom Med. 1997 Sep-Oct;59(5):533-40. Resumo
43. Bonnet MH, Arand DL. Heart rate variability in insomniacs and matched normal sleepers. Psychosom Med. 1998 Sep-Oct;60(5):610-5. Resumo
44. Dodds KL, Miller CB, Kyle SD, et al. Heart rate variability in insomnia patients: a critical review of the literature. Sleep Med Rev. 2017 Jun;33:88-100. Resumo
45. Vgontzas AN, Bixler EO, Lin HM, et al. Chronic insomnia is associated with nyctohemeral activation of the hypothalamic-pituitary-adrenal axis: clinical implications. J Clin Endocrinol Metab. 2001 Aug;86(8):3787-94. Resumo
46. Vgontzas AN, Tsigos C, Bixler EO, et al. Chronic insomnia and activity of the stress system: a preliminary study. J Psychosom Res. 1998 Jul;45(1):21-31. Resumo
47. Riemann D, Klein T, Rodenbeck A, et al. Nocturnal cortisol and melatonin secretion in primary insomnia. Psychiatry Res. 2002 Dec 15;113(1-2):17-27. Resumo
48. Wang ZJ, Liu JF. The molecular basis of insomnia: implication for therapeutic approaches. Drug Dev Res. 2016 Dec;77(8):427-36. Resumo
49. Katz DA, McHorney CA. The relationship between insomnia and health-related quality of life in patients with chronic illness. J Fam Pract. 2002 Mar;51(3):229-35. Resumo
50. Hertenstein E, Feige B, Gmeiner T, et al. Insomnia as a predictor of mental disorders: a systematic review and meta-analysis. Sleep Med Rev. 2019 Feb;43:96-105. Resumo
51. Léger D, Massuel MA, Metlaine A; SISYPHE Study Group. Professional correlates of insomnia. Sleep. 2006 Feb;29(2):171-8. Resumo
52. Hägg SA, Torén K, Lindberg E. Role of sleep disturbances in occupational accidents among women. Scand J Work Environ Health. 2015 Jul;41(4):368-76.Texto completo Resumo
53. Sivertsen B, Øverland S, Pallesen S, et al. Insomnia and long sleep duration are risk factors for later work disability. The Hordaland Health Study. J Sleep Res. 2009 Mar;18(1):122-8.Texto completo Resumo
54. Pillai V, Cheng P, Kalmbach DA, et al. Prevalence and predictors of prescription sleep aid use among individuals with DSM-5 insomnia: the role of hyperarousal. Sleep. 2016 Apr 1;39(4):825-32.Texto completo Resumo
55. He Q, Zhang P, Li G, et al. The association between insomnia symptoms and risk of cardio-cerebral vascular events: a meta-analysis of prospective cohort studies. Eur J Prev Cardiol. 2017 Jul;24(10):1071-82. Resumo
56. Fernandez-Mendoza J, Vgontzas AN, Liao D, et al. Insomnia with objective short sleep duration and incident hypertension: the Penn State Cohort. Hypertension. 2012 Oct;60(4):929-35.Texto completo Resumo
57. Suka M, Yoshida K, Sugimori H. Persistent insomnia is a predictor of hypertension in Japanese male workers. J Occup Health. 2003 Nov;45(6):344-50. Resumo
58. Vgontzas AN, Liao D, Pejovic S, et al. Insomnia with objective short sleep duration is associated with type 2 diabetes: a population-based study. Diabetes Care. 2009 Nov;32(11):1980-5.Texto completo Resumo
59. Li Y, Zhang X, Winkelman JW, et al. Association between insomnia symptoms and mortality: a prospective study of US men. Circulation. 2014 Feb 18;129(7):737-46.Texto completo Resumo
60. Parthasarathy S, Vasquez MM, Halonen M, et al. Persistent insomnia is associated with mortality risk. Am J Med. 2015 Mar;128(3):268-75.Texto completo Resumo
61. Jarrin DC, Alvaro PK, Bouchard MA, et al. Insomnia and hypertension: a systematic review. Sleep Med Rev. 2018 Oct;41:3-38. Resumo
62. Zheng B, Yu C, Lv J, et al; China Kadoorie Biobank Collaborative Group. Insomnia symptoms and risk of cardiovascular diseases among 0.5 million adults: a 10-year cohort. Neurology. 2019 Dec 3;93(23):e2110-20. Resumo
63. Lovato N, Lack L. Insomnia and mortality: a meta-analysis. Sleep Med Rev. 2019 Feb;43:71-83. Resumo
64. de Almondes KM, Costa MV, Malloy-Diniz LF, et al. Insomnia and risk of dementia in older adults: systematic review and meta-analysis. J Psychiatr Res. 2016 Jun;77:109-15. Resumo
65. Shi L, Chen SJ, Ma MY, et al. Sleep disturbances increase the risk of dementia: a systematic review and meta-analysis. Sleep Med Rev. 2018 Aug;40:4-16. Resumo
66. Gottesman RF, Lutsey PL, Benveniste H, et al. Impact of sleep disorders and disturbed sleep on brain health: a scientific statement from the American Heart Association. Stroke. 2024 Mar;55(3):e61-76.Texto completo Resumo
67. Khan MA, Al-Jahdali H. The consequences of sleep deprivation on cognitive performance. Neurosciences (Riyadh). 2023 Apr;28(2):91-9.Texto completo Resumo
68. Aasvik J, Stiles TC, Woodhouse A, et al. The effect of insomnia on neuropsychological functioning in patients with comorbid symptoms of pain, fatigue, and mood disorders. Arch Clin Neuropsychol. 2018 Feb 1;33(1):14-23.Texto completo Resumo
69. Avidan AY, Fries BE, James ML, et al. Insomnia and hypnotic use, recorded in the minimum data set, as predictors of falls and hip fractures in Michigan nursing homes. J Am Geriatr Soc. 2005 Jun;53(6):955-62. Resumo
70. Stone KL, Blackwell TL, Ancoli-Israel S, et al; Osteoporotic Fractures in Men Study Group. Sleep disturbances and risk of falls in older community-dwelling men: the Outcomes of Sleep Disorders in Older Men (MrOS Sleep) Study. J Am Geriatr Soc. 2014 Feb;62(2):299-305.Texto completo Resumo
71. Perrier J, Bertran F, Marie S, et al. Impaired driving performance associated with effect of time duration in patients with primary insomnia. Sleep. 2014 Sep 1;37(9):1565-73.Texto completo Resumo
72. Laugsand LE, Strand LB, Vatten LJ, et al. Insomnia symptoms and risk for unintentional fatal injuries - the HUNT Study. Sleep. 2014 Nov 1;37(11):1777-86.Texto completo Resumo
73. Boyd JH, Weissman MM. Epidemiology of affective disorders: a reexamination and future directions. Arch Gen Psychiatry. 1981 Sep;38(9):1039-46. Resumo
74. Johnson EO, Roth T, Schultz L, et al. Epidemiology of DSM-IV insomnia in adolescence: lifetime prevalence, chronicity, and an emergent gender difference. Pediatrics. 2006 Feb;117(2):e247-56. Resumo
75. Manber R, Bootzin RR. Sleep and the menstrual cycle. Health Psychol. 1997 May;16(3):209-14. Resumo
76. Gislason T, Reynisdottir H, Kristbjarnarson H, et al. Sleep habits and sleep disturbances among the elderly: an epidemiological survey. J Intern Med. 1993 Jul;234(1):31-9. Resumo
77. Janson C, Lindberg E, Gislason T, et al. Insomnia in men: a 10-year prospective population based study. Sleep. 2001 Jun 15;24(4):425-30. Resumo
78. Leysen L, Lahousse A, Nijs J, et al. Prevalence and risk factors of sleep disturbances in breast cancer survivors: systematic review and meta-analyses. Support Care Cancer. 2019 Dec;27(12):4401-33. Resumo
79. Ragnoli B, Pochetti P, Raie A, et al. Comorbid Insomnia and Obstructive Sleep Apnea (COMISA): current concepts of patient management. Int J Environ Res Public Health. 2021 Sep 1;18(17):9248.Texto completo Resumo
80. Anand S, Tong H, Besag FMC, et al. Safety, tolerability and efficacy of drugs for treating behavioural insomnia in children with attention-deficit/hyperactivity disorder: a systematic review with methodological quality assessment. Paediatr Drugs. 2017 Jun;19(3):235-50. Resumo
81. Lobo LL, Tufik S. Effects of alcohol on sleep parameters of sleep-deprived healthy volunteers. Sleep. 1997 Jan;20(1):52-9. Resumo
82. Curatolo PW, Robertson D. The health consequences of caffeine. Ann Intern Med. 1983 May;98(5 Pt 1):641-53. Resumo
83. Clark I, Landolt HP. Coffee, caffeine, and sleep: a systematic review of epidemiological studies and randomized controlled trials. Sleep Med Rev. 2017 Feb;31:70-8. Resumo
84. Soldatos CR, Kales JD, Scharf MB, et al. Cigarette smoking associated with sleep difficulty. Science. 1980 Feb 1;207(4430):551-3. Resumo
85. Sandsmark DK, Elliott JE, Lim MM. Sleep-wake disturbances after traumatic brain injury: synthesis of human and animal studies. Sleep. 2017 May 1;40(5):zsx044.Texto completo Resumo
86. Amara AW, Chahine LM, Videnovic A. Treatment of sleep dysfunction in Parkinson's disease. Curr Treat Options Neurol. 2017 Jul;19(7):26.Texto completo Resumo
87. Cingi C, Emre IE, Muluk NB. Jetlag related sleep problems and their management: a review. Travel Med Infect Dis. 2018 Jul-Aug;24:59-64. Resumo
88. Richardson GS, Miner JD, Czeisler CA. Impaired driving performance in shiftworkers: the role of the circadian system in a multifactorial model. Alcohol Drugs Driving. 1989-1990;5-6(4-1):265-73. Resumo
89. Schutte-Rodin S, Broch L, Buysse D, et al. Clinical guideline for the evaluation and management of chronic insomnia in adults. J Clin Sleep Med. 2008 Oct 15;4(5):487-504.Texto completo Resumo
90. Ohayon MM, Lemoine P, Arnaud-Briant V, et al. Prevalence and consequences of sleep disorders in a shift worker population. J Psychosom Res. 2002 Jul;53(1):577-83. Resumo
91. Booker LA, Magee M, Rajaratnam SMW, et al. Individual vulnerability to insomnia, excessive sleepiness and shift work disorder amongst healthcare shift workers. A systematic review. Sleep Med Rev. 2018 Oct;41:220-33. Resumo
92. Gupta L, Morgan K, Gilchrist S. Does elite sport degrade sleep quality? A systematic review. Sports Med. 2017 Jul;47(7):1317-33.Texto completo Resumo
93. Yang Y, Shin JC, Li D, et al. Sedentary behavior and sleep problems: a systematic review and meta-analysis. Int J Behav Med. 2017 Aug;24(4):481-92. Resumo
94. Carney CE, Buysse DJ, Ancoli-Israel S, et al. The consensus sleep diary: standardizing prospective sleep self-monitoring. Sleep. 2012 Feb 1;35(2):287-302.Texto completo Resumo
95. Smith MT, McCrae CS, Cheung J, et al. Use of actigraphy for the evaluation of sleep disorders and circadian rhythm sleep-wake disorders: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2018 Jul 15;14(7):1231-7.Texto completo Resumo
96. Herscovitch J, Broughton R. Sensitivity of the Stanford Sleepiness Scale to the effects of cumulative partial sleep deprivation and recovery oversleeping. Sleep. 1981;4(1):83-91. Resumo
97. Bastien CH, Vallieres A, Morin CM. Validation of the Insomnia Severity Index as an outcome measure for insomnia research. Sleep Med. 2001 Jul;2(4):297-307. Resumo
98. Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001 Sep;16(9):606-13.Texto completo Resumo
99. Spitzer RL, Kroenke K, Williams JB, et al. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006 May 22;166(10):1092-7.Texto completo Resumo
100. Johns MW. A new method for measuring daytime sleepiness: the Epworth Sleepiness Scale. Sleep. 1991 Dec;14(6):540-5. Resumo
101. Soldatos CR, Dikeos DG, Paparrigopoulos TJ. The diagnostic validity of the Athens Insomnia Scale. J Psychosom Res. 2003 Sep;55(3):263-7. Resumo
102. Tombaugh TN, McIntyre NJ. The Mini-Mental State Examination: a comprehensive review. J Am Geriatr Soc. 1992 Sep;40(9):922-35. Resumo
103. de Souza L, Benedito-Silva AA, Pires ML, et al. Further validation of actigraphy for sleep studies. Sleep. 2003 Feb 1;26(1):81-5. Resumo
104. Sateia MJ, Buysse DJ, Krystal AD, et al. Clinical practice guideline for the pharmacologic treatment of chronic insomnia in adults: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2017 Feb 15;13(2):307-49.Texto completo Resumo
105. Buysse DJ, Reynolds CF 3rd, Monk TH, et al. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res. 1989 May;28(2):193-213. Resumo
106. Riemann D, Baglioni C, Bassetti C, et al. European guideline for the diagnosis and treatment of insomnia. J Sleep Res. 2017 Dec;26(6):675-700.Texto completo Resumo
107. van Straten A, van der Zweerde T, Kleiboer A, et al. Cognitive and behavioral therapies in the treatment of insomnia: a meta-analysis. Sleep Med Rev. 2018 Apr;38:3-16. Resumo
108. Perlis ML, Smith MT, Benson-Jungquist C, et al. Cognitive behavioral treatment of insomnia: a session-by-session guide. New York, NY: Springer Science+Business Media, Inc.; 2005.
109. Dawson SC, Krakow B, Haynes PL, et al. Use of sleep aids in insomnia: the role of time monitoring behavior. Prim Care Companion CNS Disord. 2023 May 16;25(3):22m03344.Texto completo Resumo
110. Miller CB, Espie CA, Epstein DR, et al. The evidence base of sleep restriction therapy for treating insomnia disorder. Sleep Med Rev. 2014 Oct;18(5):415-24. Resumo
111. Nielson SA, Perez E, Soto P, et al. Challenging beliefs for quality sleep: a systematic review of maladaptive sleep beliefs and treatment outcomes following cognitive behavioral therapy for insomnia. Sleep Med Rev. 2023 Dec;72:101856. Resumo
112. Cheng SK, Dizon J. Computerised cognitive behavioural therapy for insomnia: a systematic review and meta-analysis. Psychother Psychosom. 2012;81(4):206-16. Resumo
113. Morin CM, Vallières A, Guay B, et al. Cognitive behavioral therapy, singly and combined with medication, for persistent insomnia: a randomized controlled trial. JAMA. 2009 May 20;301(19):2005-15.Texto completo Resumo
114. Morin CM, Bootzin RR, Buysse DJ, et al. Psychological and behavioral treatment of insomnia: update of the recent evidence (1998-2004). Sleep. 2006 Nov;29(11):1398-414. Resumo
115. Mitchell MD, Gehrman P, Perlis M, et al. Comparative effectiveness of cognitive behavioral therapy for insomnia: a systematic review. BMC Fam Pract. 2012 May 25;13:40.Texto completo Resumo
116. Buysse DJ. Insomnia. JAMA. 2013 Feb 20;309(7):706-16.Texto completo Resumo
117. Sun J, Kang J, Wang P, et al. Self-relaxation training can improve sleep quality and cognitive functions in the older: a one-year randomised controlled trial. J Clin Nurs. 2013 May;22(9-10):1270-80. Resumo
118. Vitiello MV, McCurry SM, Shortreed SM, et al. Cognitive-behavioral treatment for comorbid insomnia and osteoarthritis pain in primary care: the Lifestyles randomized controlled trial. J Am Geriatr Soc. 2013 Jun;61(6):947-56.Texto completo Resumo
119. Black DS, O'Reilly GA, Olmstead R, et al. Mindfulness meditation and improvement in sleep quality and daytime impairment among older adults with sleep disturbances: a randomized clinical trial. JAMA Intern Med. 2015 Apr;175(4):494-501.Texto completo Resumo
120. Wu JQ, Appleman ER, Salazar RD, et al. Cognitive behavioral therapy for insomnia comorbid with psychiatric and medical conditions: a meta-analysis. JAMA Intern Med. 2015 Sep;175(9):1461-72.Texto completo Resumo
121. Brasure M, Fuchs E, MacDonald R, et al. Psychological and behavioral interventions for managing insomnia disorder: an evidence report for a clinical practice guideline by the American College of Physicians. Ann Intern Med. 2016 Jul 19;165(2):113-24. Resumo
122. Brasure M, MacDonald R, Fuchs E, et al; Agency for Healthcare Research and Quality. Management of insomnia disorder. Dec 2015 [internet publication].Texto completo Resumo
123. Rash JA, Kavanagh VAJ, Garland SN. A meta-analysis of mindfulness-based therapies for insomnia and sleep disturbance: moving towards processes of change. Sleep Med Clin. 2019 Jun;14(2):209-33. Resumo
124. Qaseem A, Kansagara D, Forciea MA, et al. Management of chronic insomnia disorder in adults: a clinical practice guideline from the American College of Physicians. Ann Intern Med. 2016 Jul 19;165(2):125-33.Texto completo Resumo
125. Edinger JD, Arnedt JT, Bertisch SM, et al. Behavioral and psychological treatments for chronic insomnia disorder in adults: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2021 Feb 1;17(2):255-62.Texto completo Resumo
126. Alberta Medical Association: Toward Optimized Practice. Assessment to management of adult insomnia. Dec 2015 [internet publication].Texto completo
127. Australian Prescriber Editorial Executive Committee. Lemborexant for insomnia. Aust Prescr. 2022 Feb;45(1):29-30.Texto completo Resumo
128. Mignot E, Mayleben D, Fietze I, et al. Safety and efficacy of daridorexant in patients with insomnia disorder: results from two multicentre, randomised, double-blind, placebo-controlled, phase 3 trials. Lancet Neurol. 2022 Feb;21(2):125-39. Resumo
129. Wilson S, Anderson K, Baldwin D, et al. British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders: an update. J Psychopharmacol. 2019 Aug;33(8):923-47.Texto completo Resumo
130. Ree M, Junge M, Cunnington D. Australasian Sleep Association position statement regarding the use of psychological/behavioral treatments in the management of insomnia in adults. Sleep Med. 2017 Aug;36(suppl 1):S43-7.Texto completo Resumo
131. Manber R, Bei B, Simpson N, et al. Cognitive behavioral therapy for prenatal insomnia: a randomized controlled trial. Obstet Gynecol. 2019 May;133(5):911-9.Texto completo Resumo
132. Felder JN, Epel ES, Neuhaus J, et al. Efficacy of digital cognitive behavioral therapy for the treatment of insomnia symptoms among pregnant women: a randomized clinical trial. JAMA Psychiatry. 2020 May 1;77(5):484-92.Texto completo Resumo
133. Riemann D, Perlis ML. The treatments of chronic insomnia: a review of benzodiazepine receptor agonists and psychological and behavioral therapies. Sleep Med Rev. 2009 Jun;13(3):205-14. Resumo
134. Morin CM, Culbert JP, Schwartz SM. Nonpharmacological interventions for insomnia: a meta-analysis of treatment efficacy. Am J Psychiatry. 1994 Aug;151(8):1172-80. Resumo
135. Johnson JA, Rash JA, Campbell TS, et al. A systematic review and meta-analysis of randomized controlled trials of cognitive behavior therapy for insomnia (CBT-I) in cancer survivors. Sleep Med Rev. 2016 Jun;27:20-8. Resumo
136. Cheung JMY, Jarrin DC, Ballot O, et al. A systematic review of cognitive behavioral therapy for insomnia implemented in primary care and community settings. Sleep Med Rev. 2019 Apr;44:23-36. Resumo
137. Davidson JR, Dickson C, Han H. Cognitive behavioural treatment for insomnia in primary care: a systematic review of sleep outcomes. Br J Gen Pract. 2019 Aug 29;69(686):e657-64.Texto completo Resumo
138. Koffel E, Bramoweth AD, Ulmer CS. Increasing access to and utilization of cognitive behavioral therapy for insomnia (CBT-I): a narrative review. J Gen Intern Med. 2018 Jun;33(6):955-62.Texto completo Resumo
139. Seyffert M, Lagisetty P, Landgraf J, et al. Internet-delivered cognitive behavioral therapy to treat insomnia: a systematic review and meta-analysis. PLoS One. 2016 Feb 11;11(2):e0149139.Texto completo Resumo
140. Zachariae R, Lyby MS, Ritterband LM, et al. Efficacy of internet delivered cognitive-behavioral therapy for insomnia: a systematic review and meta-analysis of randomized controlled trials. Sleep Med Rev. 2016 Dec;30:1-10. Resumo
141. National Institute for Health and Care Excellence. Sleepio to treat insomnia and insomnia symptoms. May 2022 [internet publication].Texto completo
142. Deschenes CL, McCurry SM. Current treatments for sleep disturbances in individuals with dementia. Curr Psychiatry Rep. 2009 Feb;11(1):20-6.Texto completo Resumo
143. McCurry SM, Gibbons LE, Logsdon RG, et al. Nighttime insomnia treatment and education for Alzheimer's disease: a randomized, controlled trial. J Am Geriatr Soc. 2005 May;53(5):793-802. Resumo
144. Lamarche LJ, De Koninck J. Sleep disturbance in adults with posttraumatic stress disorder: a review. J Clin Psychiatry. 2007 Aug;68(8):1257-70. Resumo
145. Ballesio A, Aquino M, Feige B, et al. The effectiveness of behavioural and cognitive behavioural therapies for insomnia on depressive and fatigue symptoms: a systematic review and network meta-analysis. Sleep Medicine Reviews. 2018 Feb;37:114-29. Resumo
146. Cunningham JEA, Shapiro CM. Cognitive behavioural therapy for insomnia (CBT-I) to treat depression: a systematic review. J Psychosom Res. 2018 Mar;106:1-12. Resumo
147. Gebara MA, Siripong N, DiNapoli EA, et al. Effect of insomnia treatments on depression: a systematic review and meta-analysis. Depress Anxiety. 2018 Aug;35(8):717-31. Resumo
148. Alimoradi Z, Jafari E, Broström A, et al. Effects of cognitive behavioral therapy for insomnia (CBT-I) on quality of life: a systematic review and meta-analysis. Sleep Med Rev. 2022 Aug;64:101646.Texto completo Resumo
149. Savin KL, Clark TL, Perez-Ramirez P, et al. The effect of cognitive behavioral therapy for insomnia (CBT-I) on cardiometabolic health biomarkers: a systematic review of randomized controlled trials. Behav Sleep Med. 2023 Nov 2;21(6):671-94.Texto completo Resumo
150. Chung KF, Lee CT, Yeung WF, et al. Sleep hygiene education as a treatment of insomnia: a systematic review and meta-analysis. Fam Pract. 2018 Jul; 35(4):365-75. Resumo
151. van Straten A, Cuijpers P. Self-help therapy for insomnia: a meta-analysis. Sleep Med Rev. 2009 Feb;13(1):61-71. Resumo
152. Yang PY, Ho KH, Chen HC, et al. Exercise training improves sleep quality in middle-aged and older adults with sleep problems: a systematic review. J Physiother. 2012;58(3):157-63.Texto completo Resumo
153. Rubio-Arias JÁ, Marín-Cascales E, Ramos-Campo DJ, et al. Effect of exercise on sleep quality and insomnia in middle-aged women: a systematic review and meta-analysis of randomized controlled trials. Maturitas. 2017 Jun;100:49-56. Resumo
154. Taibi DM, Landis CA, Petry H, et al. A systematic review of valerian as a sleep aid: safe but not effective. Sleep Med Rev. 2007 Jun;11(3):209-30. Resumo
155. Meolie AL, Rosen C, Kristo D, et al. Oral nonprescription treatment for insomnia: an evaluation of products with limited evidence. J Clin Sleep Med. 2005 Apr 15;1(2):173-87. Resumo
156. Cooper KL, Relton C. Homeopathy for insomnia: a systematic review of research evidence. Sleep Med Rev. 2010 Oct;14(5):329-37. Resumo
157. Cooper KL, Relton C. Homeopathy for insomnia: summary of additional RCT published since systematic review. Sleep Med Rev. 2010 Dec;14(6):411. Resumo
158. Kalavapalli R, Singareddy R. Role of acupuncture in the treatment of insomnia: a comprehensive review. Complement Ther Clin Pract. 2007 Aug;13(3):184-93. Resumo
159. Lee SH, Lim SM. Acupuncture for insomnia after stroke: a systematic review and meta-analysis. BMC Complement Altern Med. 2016 Jul 19;16:228.Texto completo Resumo
160. Cao HJ, Yu ML, Wang LQ, et al. Acupuncture for primary insomnia: an updated systematic review of randomized controlled trials. J Altern Complement Med. 2019 May; 25(5):451-74. Resumo
161. He W, Li M, Zuo L, et al. Acupuncture for treatment of insomnia: an overview of systematic reviews. Complement Ther Med. 2019 Feb;42:407-16. Resumo
162. Cheuk DK, Yeung WF, Chung KF, et al. Acupuncture for insomnia. Cochrane Database Syst Rev. 2012 Sep 12;(9):CD005472.Texto completo Resumo
163. Herring WJ, Snyder E, Budd K, et al. Orexin receptor antagonism for treatment of insomnia: a randomized clinical trial of suvorexant. Neurology. 2012 Dec 4;79(23):2265-74. Resumo
164. Wilt TJ, MacDonald R, Brasure M, et al. Pharmacologic treatment of insomnia disorder: an evidence report for a clinical practice guideline by the American College of Physicians. Ann Intern Med. 2016 Jul 19;165(2):103-12. Resumo
165. Herring WJ, Connor KM, Snyder E, et al. Suvorexant in elderly patients with insomnia: pooled analyses of data from phase III randomized controlled clinical trials. Am J Geriatr Psychiatry. 2017 Jul;25(7):791-802. Resumo
166. Kuriyama A, Tabata H. Suvorexant for the treatment of primary insomnia: a systematic review and meta-analysis. Sleep Med Rev. 2017 Oct;35:1-7. Resumo
167. McElroy H, O'Leary B, Adena M, et al. Comparative efficacy of lemborexant and other insomnia treatments: a network meta-analysis. J Manag Care Spec Pharm. 2021 Sep;27(9):1296-308.Texto completo Resumo
168. Greenblatt DJ, Roth T. Zolpidem for insomnia. Expert Opin Pharmacother. 2012 Apr;13(6):879-93. Resumo
169. Griffin CE 3rd, Kaye AM, Bueno FR, et al. Benzodiazepine pharmacology and central nervous system-mediated effects. Ochsner J. 2013 Summer;13(2):214-23.Texto completo Resumo
170. Griffiths RR, Johnson MW. Relative abuse liability of hypnotic drugs: a conceptual framework and algorithm for differentiating among compounds. J Clin Psychiatry. 2005;66 Suppl 9:31-41. Resumo
171. Mayer G, Wang-Weigand S, Roth-Schechter B, et al. Efficacy and safety of 6-month nightly ramelteon administration in adults with chronic primary insomnia. Sleep. 2009 Mar;32(3):351-60.Texto completo Resumo
172. Auld F, Maschauer EL, Morrison I, et al. Evidence for the efficacy of melatonin in the treatment of primary adult sleep disorders. Sleep Med Rev. 2017 Aug;34:10-22. Resumo
173. Pan B, Ge L, Lai H, et al. The comparative effectiveness and safety of insomnia drugs: a systematic review and network meta-analysis of 153 randomized trials. Drugs. 2023 May;83(7):587-619. Resumo
174. De Crescenzo F, D'Alò GL, Ostinelli EG, et al. Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis. Lancet. 2022 Jul 16;400(10347):170-84.Texto completo Resumo
175. Barkopoulos P, Cho JH. Hypnotic medications as an adjunct treatment to cognitive behavioral therapy for insomnia. Sleep Med Clin. 2023 Mar;18(1):95-111. Resumo
176. Morin CM, Edinger JD, Beaulieu-Bonneau S, et al. Effectiveness of sequential psychological and medication therapies for insomnia disorder: a randomized clinical trial. JAMA Psychiatry. 2020 Nov 1;77(11):1107-15.Texto completo Resumo
177. Everitt H, Baldwin DS, Stuart B, et al. Antidepressants for insomnia in adults. Cochrane Database Syst Rev. 2018 May 14;(5):CD010753.Texto completo Resumo
178. Richardson GS, Roehrs TA, Rosenthal L, et al. Tolerance to daytime sedative effects of H1 antihistamines. J Clin Psychopharmacol. 2002 Oct;22(5):511-5. Resumo
179. 2023 American Geriatrics Society Beers Criteria® Update Expert Panel. American Geriatrics Society 2023 updated AGS Beers Criteria® for potentially inappropriate medication use in older adults. J Am Geriatr Soc. 2023 Jul;71(7):2052-81.Texto completo Resumo
180. Fietze I, Bassetti CLA, Mayleben DW, et al. Efficacy and safety of daridorexant in older and younger adults with insomnia disorder: a secondary analysis of a randomised placebo-controlled trial. Drugs Aging. 2022 Oct;39(10):795-810.Texto completo Resumo
181. Zammit G, Dauvilliers Y, Pain S, et al. Daridorexant, a new dual orexin receptor antagonist, in elderly subjects with insomnia disorder. Neurology. 2020 May 26;94(21):e2222-32. Resumo
182. Rosenberg R, Murphy P, Zammit G, et al. Comparison of lemborexant with placebo and zolpidem tartrate extended release for the treatment of older adults with insomnia disorder: a phase 3 randomized clinical trial. JAMA Netw Open. 2019 Dec 2;2(12):e1918254.Texto completo Resumo
183. Pollack M, Kinrys G, Krystal A, et al. Eszopiclone coadministered with escitalopram in patients with insomnia and comorbid generalized anxiety disorder. Arch Gen Psychiatry. 2008 May;65(5):551-62. Resumo
184. Ji JL, Liu WJ, Zhang N, et al. Effects of paroxetine with or without zolpidem on depression with insomnia: a multi-center randomized comparative study [in Chinese]. Zhonghua Yi Xue Za Zhi. 2007 Jun 19;87(23):1585-9. Resumo
185. Fava M, Asnis GM, Shrivastava R, et al. Zolpidem extended-release improves sleep and next-day symptoms in comorbid insomnia and generalized anxiety disorder. J Clin Psychopharmacol. 2009 Jun;29(3):222-30. Resumo
186. Ensrud KEJ, Sternfeld BL. Effect of escitalopram on insomnia symptoms and subjective sleep quality in healthy perimenopausal and postmenopausal women with hot flashes: a randomized controlled trial. Menopause. 2012 Aug;19(8):848-55.Texto completo Resumo
187. Fava M, Asnis GM, Shrivastava RK, et al. Improved insomnia symptoms and sleep-related next-day functioning in patients with comorbid major depressive disorder and insomnia following concomitant zolpidem extended-release 12.5 mg and escitalopram treatment: a randomized controlled trial. J Clin Psychiatry. 2011 Jul;72(7):914-28. Resumo
188. McCall WV, Benca RM, Rosenquist PB, et al. Reducing Suicidal Ideation Through Insomnia Treatment (REST-IT): a randomized clinical trial. Am J Psychiatry. 2019 Nov 1;176(11):957-65.Texto completo Resumo
189. Karsten J, Hagenauw LA, Kamphuis J, et al. Low doses of mirtazapine or quetiapine for transient insomnia: a randomised, double-blind, cross-over, placebo-controlled trial. J Psychopharmacol. 2017 Mar;31(3):327-37. Resumo
190. Krystal A, Fava M, Rubens R, et al. Evaluation of eszopiclone discontinuation after cotherapy with fluoxetine for insomnia with coexisting depression. J Clin Sleep Med. 2007 Feb 15;3(1):48-55.Texto completo Resumo
191. Kinnunen KM, Vikhanova A, Livingston G. The management of sleep disorders in dementia: an update. Curr Opin Psychiatry. 2017 Nov;30(6):491-7.Texto completo Resumo
192. Lenzer J. FDA warns about using antipsychotic drugs for dementia. BMJ. 2005 Apr 23;330(7497):922. [Erratum in: BMJ. 2005 May 28;330(7502):1258.]Texto completo Resumo
193. Ishikawa I, Shinno H, Ando N, et al. The effect of memantine on sleep architecture and psychiatric symptoms in patients with Alzheimer's disease. Acta Neuropsychiatr. 2016 Jun;28(3):157-64. Resumo
194. Cummings JL, Isaacson RS, Schmitt FA, et al. A practical algorithm for managing Alzheimer's disease: what, when, and why? Ann Clin Transl Neurol. 2015 Mar;2(3):307-23.Texto completo Resumo
195. Jin JW, Nowakowski S, Taylor A, et al. Cognitive behavioral therapy for mood and insomnia in persons with dementia: a systematic review. Alzheimer Dis Assoc Disord. 2021 Oct-Dec 01;35(4):366-73. Resumo
196. Shub D, Darvishi R, Kunik ME. Non-pharmacologic treatment of insomnia in persons with dementia. Geriatrics. 2009 Feb;64(2):22-6. Resumo
197. McCleery J, Sharpley AL. Pharmacotherapies for sleep disturbances in dementia. Cochrane Database Syst Rev. 2020 Nov 15;(11):CD009178.Texto completo Resumo
198. James SP, Mendelson WB. The use of trazodone as a hypnotic: a critical review. J Clin Psychiatry. 2004 Jun;65(6):752-5. Resumo
199. Bronskill SE, Campitelli MA, Iaboni A, et al. Low-dose trazodone, benzodiazepines, and fall-related injuries in nursing homes: a matched-cohort study. J Am Geriatr Soc. 2018 Oct;66(10):1963-71. Resumo
200. Dyer O. FDA issues black box warnings on common insomnia drugs. BMJ. 2019 May 10;365:l2165. Resumo
201. Na HJ, Jeon N, Staatz CE, et al. Clinical safety and narcolepsy-like symptoms of dual orexin receptor antagonists in patients with insomnia: a systematic review and meta-analysis. Sleep. 2024 Feb 8;47(2):zsad293. Resumo
202. McCall WV, Benca RM, Rosenquist PB, et al. Hypnotic medications and suicide: risk, mechanisms, mitigation, and the FDA. Am J Psychiatry. 2017 Jan 1;174(1):18-25.Texto completo Resumo
203. Watson NF, Benca RM, Krystal AD, et al. Alliance for Sleep clinical practice guideline on switching or deprescribing hypnotic medications for insomnia. J Clin Med. 2023 Mar 25;12(7):2493.Texto completo Resumo
204. Roehrs TA, Randall S, Harris E, et al. Twelve months of nightly zolpidem does not lead to dose escalation: a prospective placebo-controlled study. Sleep. 2011 Feb 1;34(2):207-12.Texto completo Resumo
205. Roehrs TA, Randall S, Harris E, et al. Twelve months of nightly zolpidem does not lead to rebound insomnia or withdrawal symptoms: a prospective placebo-controlled study. J Psychopharmacol. 2012 Aug;26(8):1088-95.Texto completo Resumo
206. Krystal AD, Walsh JK, Laska E, et al. Sustained efficacy of eszopiclone over 6 months of nightly treatment: results of a randomized, double-blind, placebo-controlled study in adults with chronic insomnia. Sleep. 2003 Nov 1;26(7):793-9. Resumo
207. Morin CM, Bélanger L, Bastien C, et al. Long-term outcome after discontinuation of benzodiazepines for insomnia: a survival analysis of relapse. Behav Res Ther. 2005 Jan;43(1):1-14. Resumo
208. Ji X, Ivers H, Savard J, et al. Residual symptoms after natural remission of insomnia: associations with relapse over 4 years. Sleep. 2019 Aug 1;42(8):zsz122.Texto completo Resumo
209. Simpson N, Manber R. CBT-I in patients who wish to reduce use of hypnotic medication. In: Nowakowski S, Garland S, Grandner MA, eds. Adapting cognitive behavioral therapy for insomnia. Cambridge, MA: Academic Press; 2022:437-56.Texto completo
210. Perlis M, Gehrman P, Riemann D. Intermittent and long-term use of sedative hypnotics. Curr Pharm Des. 2008;14(32):3456-65. Resumo
211. Brooks S, Jacobs GE, de Boer P, et al. The selective orexin-2 receptor antagonist seltorexant improves sleep: an exploratory double-blind, placebo controlled, crossover study in antidepressant-treated major depressive disorder patients with persistent insomnia. J Psychopharmacol. 2019 Feb;33(2):202-9. Resumo
212. Hoyer D, Allen A, Jacobson LH. Hypnotics with novel modes of action. Br J Clin Pharmacol. 2020 Feb;86(2):244-9.Texto completo Resumo
213. Lo HS, Yang CM, Lo HG, et al. Treatment effects of gabapentin for primary insomnia. Clin Neuropharmacol. 2010 Mar-Apr;33(2):84-90. Resumo
214. Liu GJ, Karim MR, Xu LL, et al. Efficacy and tolerability of gabapentin in adults with sleep disturbance in medical illness: a systematic review and meta-analysis. Front Neurol. 2017 Jul 14;8:316.Texto completo Resumo
215. Her J, Cho MK. Effect of aromatherapy on sleep quality of adults and elderly people: a systematic literature review and meta-analysis. Complement Ther Med. 2021 Aug;60:102739.Texto completo Resumo
216. de Diego-Cordero R, Acevedo-Aguilera R, Vega-Escaño J, et al. The use of spiritual and religious interventions for the treatment for insomnia: a scoping review. J Relig Health. 2022 Feb;61(1):507-23. Resumo
217. Mamoune S, Mener E, Chapron A, et al. Hypnotherapy and insomnia: a narrative review of the literature. Complement Ther Med. 2022 May;65:102805.Texto completo Resumo
218. Curry G, Cheung T, Zhang SD, et al. Repeated electrical vestibular nerve stimulation (VeNS) reduces severity in moderate to severe insomnia; a randomised, sham-controlled trial; the modius sleep study. Brain Stimul. 2024 Jul-Aug;17(4):782-93.Texto completo Resumo
219. Yin X, Li W, Liang T, et al. Effect of electroacupuncture on insomnia in patients with depression: a randomized clinical trial. JAMA Netw Open. 2022 Jul 1;5(7):e2220563.Texto completo Resumo
220. Zhao FY, Spencer SJ, Kennedy GA, et al. Acupuncture for primary insomnia: effectiveness, safety, mechanisms and recommendations for clinical practice. Sleep Med Rev. 2024 Apr;74:101892. Resumo
221. Liu C, Xi H, Wu W, et al. Placebo effect of acupuncture on insomnia: a systematic review and meta-analysis. Ann Palliat Med. 2020 Jan;9(1):19-29.Texto completo Resumo
222. Siu PM, Yu AP, Tam BT, et al. Effects of tai chi or exercise on sleep in older adults with insomnia: a randomized clinical trial. JAMA Netw Open. 2021 Feb 1;4(2):e2037199.Texto completo Resumo
223. Ong JC, Ulmer CS, Manber R. Improving sleep with mindfulness and acceptance: a metacognitive model of insomnia. Behav Res Ther. 2012 Nov;50(11):651-60.Texto completo Resumo
224. Jansson-Fröjmark M, Alfonsson S, Bohman B, et al. Paradoxical intention for insomnia: a systematic review and meta-analysis. J Sleep Res. 2022 Apr;31(2):e13464.Texto completo Resumo
225. Richardson G, Wang-Weigand S. Effects of long-term exposure to ramelteon, a melatonin receptor agonist, on endocrine function in adults with chronic insomnia. Hum Psychopharmacol. 2009 Mar;24(2):103-11. Resumo
O uso deste conteúdo está sujeito ao nosso aviso legal