Câncer anal

Rao S, Guren MG, Khan K, et al. Anal cancer: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2021 Sep;32(9):1087-100.Texto completo  Resumo

National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: anal carcinoma [internet publication].Texto completo

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33. Bartelink H, Roelofsen F, Eschwege F, et al. Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer radiotherapy and gastrointestinal cooperative groups. J Clin Oncol. 1997 May;15(5):2040-9. Resumo

34. Jones CM, Adams R, Downing A, et al. Toxicity, tolerability, and compliance of concurrent capecitabine or 5-fluorouracil in radical management of anal cancer with single-dose mitomycin-C and intensity modulated radiation therapy: evaluation of a national cohort. Int J Radiat Oncol Biol Phys. 2018 Aug 1;101(5):1202-11. Resumo

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37. Flam M, John M, Pajak TF, et al. Role of mitomycin in combination with fluorouracil and radiotherapy, and salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: results of a phase III randomized intergroup study. J Clin Oncol. 1996 Sep;14(9):2527-39. Resumo

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39. Goodman KA, Julie D, Cercek A, et al. Capecitabine with mitomycin reduces acute hematologic toxicity and treatment delays in patients undergoing definitive chemoradiation using intensity modulated radiation therapy for anal cancer. Int J Radiat Oncol Biol Phys. 2017 Aug 1;98(5):1087-95. Resumo

40. Gunderson LL, Winter KA, Ajani JA, et al. Long-term update of US GI intergroup RTOG 98-11 phase III trial for anal carcinoma: survival, relapse, and colostomy failure with concurrent chemoradiation involving fluorouracil/mitomycin versus fluorouracil/cisplatin. J Clin Oncol. 2012 Dec 10;30(35):4344-51.Texto completo  Resumo

41. James RD, Glynne-Jones R, Meadows HM, et al. Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial. Lancet Oncol. 2013 May;14(6):516-24.Texto completo  Resumo

42. Peiffert D, Tournier-Rangeard L, Gérard JP, et al. Induction chemotherapy and dose intensification of the radiation boost in locally advanced anal canal carcinoma: final analysis of the randomized UNICANCER ACCORD 03 trial. J Clin Oncol. 2012;30:1941-1948. Resumo

43. Bazan JG, Hara W, Hsu A, et al. Intensity-modulated radiation therapy versus conventional radiation therapy for squamous cell carcinoma of the anal canal. Cancer. 2011;117:3342-3351. Resumo

44. Gilbert A, Drinkwater K, McParland L, et al. UK national cohort of anal cancer treated with intensity-modulated radiotherapy: One-year oncological and patient-reported outcomes. Eur J Cancer. 2020 Mar;128:7-16. Resumo

45. ISRCTN registry. PLATO - personalising anal cancer radiotherapy dose. ISRCTN88455282. Sept 2021 [internet publication].Texto completo

46. Muirhead R, Partridge M, Hawkins MA. A tumor control probability model for anal squamous cell carcinoma. Radiother Oncol. 2015 Aug;116(2):192-6. Resumo

47. Moureau-Zabotto L, Viret F, Giovaninni M, et al. Is neoadjuvant chemotherapy prior to radio-chemotherapy beneficial in T4 anal carcinoma? J Surg Oncol. 2011 Jul 1;104(1):66-71. Resumo

48. Glynne-Jones R, Sebag-Montefiore D, Meadows HM, et al. Best time to assess complete clinical response after chemoradiotherapy in squamous cell carcinoma of the anus (ACT II): a post-hoc analysis of randomised controlled phase 3 trial. Lancet Oncol. 2017 Mar;18(3):347-56.Texto completo  Resumo

49. Rao S, Sclafani F, Eng C, et al. International Rare Cancers Initiative multicenter randomized phase II trial of cisplatin and fluorouracil versus carboplatin and paclitaxel in advanced anal cancer: InterAAct. J Clin Oncol. 2020 Aug 1;38(22):2510-18.Texto completo  Resumo

50. Kim S, François E, André T, et al. Docetaxel, cisplatin, and fluorouracil chemotherapy for metastatic or unresectable locally recurrent anal squamous cell carcinoma (Epitopes-HPV02): a multicentre, single-arm, phase 2 study. Lancet Oncol. 2018 Aug;19(8):1094-106. Resumo

51. Sclafani F, Morano F, Cunningham D, et al. Platinum-fluoropyrimidine and paclitaxel-based chemotherapy in the treatment of advanced anal cancer patients. Oncologist. 2017 Apr;22(4):402-8.Texto completo  Resumo

52. Phan LK, Hoff PM. Evidence of clinical activity for cetuximab combined with irinotecan in a patient with refractory anal canal squamous-cell carcinoma: report of a case. Dis Colon Rectum. 2007;50:395-398. Resumo

53. National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: cancer in people with HIV [internet publication].Texto completo

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55. Seo Y, Kinsella MT, Reynolds HL, et al. Outcomes of chemoradiotherapy with 5-Fluorouracil and mitomycin C for anal cancer in immunocompetent versus immunodeficient patients. Int J Radiat Oncol Biol Phys. 2009 Sep 1;75(1):143-9. Resumo

56. Ajani JA, Winter KA, Gunderson LL, et al. US intergroup anal carcinoma trial: tumor diameter predicts for colostomy. J Clin Oncol. 2009 Mar 1;27(7):1116-21.Texto completo  Resumo

57. Ajani JA, Winter KA, Gunderson LL, et al. Prognostic factors derived from a prospective database dictate clinical biology of anal cancer: the intergroup trial (RTOG 98-11). Cancer. 2010 Sep 1;116(17):4007-13.Texto completo  Resumo

58. Goffredo P, Garancini M, Robinson TJ, et al. A national-level validation of the new American Joint Committee on Cancer 8th edition subclassification of stage IIA and B anal squamous cell cancer. Ann Surg Oncol. 2018 Jun;25(6):1654-60. Resumo

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60. Peiffert D, Bey P, Pernot M, et al. Conservative management by irradiation of epidermoid cancers of the anal canal: prognostic factors of tumor control and complications. Int J Radiat Oncol Biol Phys. 1997;37:313-324. Resumo

61. Gerard JP, Ayzac L, Hun D, et al. Treatment of anal canal carcinoma with high dose radiation therapy and concomitant fluorouracil-cisplatinum: long term results in 95 patients. Radiother Oncol. 1998;46:249-256. Resumo

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63. Ajani JA, Winter KA, Gunderson LL, et al. Fluorouracil, mitomycin, and radiotherapy vs fluorouracil, cisplatin, and radiotherapy for carcinoma of the anal canal: a randomized controlled trial. JAMA. 2008 Apr 23;299(16):1914-21.Texto completo  Resumo

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66. Kapp KS, Geyer E, Gebhart FH, et al. Evaluation of sphincter function after external beam irradiation and Ir-192 high-dose-rate (HDR) brachytherapy +/- chemotherapy in patients with carcinoma of the anal canal. Int J Radiat Oncol Biol Phys. 1999;45:339.

67. Tournier-Rangeard L, Mercier M, Peiffert D, et al. Radiochemotherapy of locally advanced anal canal carcinoma: prospective assessment of early impact on the quality of life (randomized trial ACCORD 03). Radiother Oncol. 2008;87:391-397. Resumo

68. Weber DC, Nouet P, Kurtz JM, et al. Assessment of target dose delivery in anal cancer using in vivo thermoluminescent dosimetry. Radiother Oncol. 2001;59:39-43. Resumo

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