Cuidados paliativos

Referências

Principais artigos

National Institute for Health and Care Excellence. Improving supportive and palliative care for adults with cancer. March 2004 [internet publication].Texto completo

National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: adult cancer pain [internet publication].Texto completo

National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: palliative care [internet publication].Texto completo

Ferrell BR, Temel JS, Temin S, et al. Integration of palliative care into standard oncology care: American Society of Clinical Oncology clinical practice guideline update. J Clin Oncol. 2017 Jan;35(1):96-112.Texto completo  Resumo

Andersen BL, Lacchetti C, Ashing K, et al. Management of anxiety and depression in adult survivors of cancer: ASCO guideline update. J Clin Oncol. 2023 Jun 20;41(18):3426-53.Texto completo  Resumo

Artigos de referência

1. Center to Advance Palliative Care. Policy Matters [internet publication].Texto completo

2. Kelley AS, Morrison RS. Palliative care for the seriously ill. N Engl J Med. 2015 Aug 20;373(8):747-55.Texto completo  Resumo

3. Parikh RB, Kirch RA, Smith TJ, et al. Early specialty palliative care - translating data on oncology into practice. New Engl J Med. 2013 Dec 12;369(24):2347-51.Texto completo  Resumo

4. Office for National Statistics. National life tables, UK: 2015 to 2017. Sep 2019 [internet publication].Texto completo

5. National Institute for Health and Care Excellence. Improving supportive and palliative care for adults with cancer. March 2004 [internet publication].Texto completo

6. World Health Organization. Top 10 causes of death. Dec 2020 [internet publication].Texto completo

7. Population Division, United Nations. World population ageing 1950-2050: VI. conclusions. 2001 [internet publication].Texto completo

8. Naqvi F, Cervo F, Fields S. Evidence-based review of interventions to improve palliation of pain, dyspnea, depression. Geriatrics. 2009 Aug;64(8):8-10, 12-4. Resumo

9. United Nations Programme on Ageing. Th eMadrid international plan of action on ageing. New York; UN Department of Economics and Social Affairs: 2002 [internet publication].Texto completo

10. A controlled trial to improve care for seriously ill hospitalized patients: The Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments (SUPPORT). The SUPPORT Principal Investigators. JAMA. 1995 Nov 22-29;274(20):1591-8. Resumo

11. Higginson IJ, Sen-Gupta GJA. Place of care in advanced cancer: a qualitative systematic literature review of patient preferences. J Palliat Med. 2000;3(3):287-300. Resumo

12. Teno JM, Freedman VA, Kasper JD, et al. Is care for the dying improving in the United States? J Palliat Med. 2015 Aug;18(8):662-6. Resumo

13. Carson SS, Cox CE, Wallenstein S, et al. Effect of palliative care-led meetings for families of patients with chronic critical illness: a randomized clinical trial. JAMA. 2016 Jul 5;316(1):51-62.Texto completo  Resumo

14. Institute of Medicine. Dying in America: improving quality and honoring individual preferences near the end of life. National Academies Press, Washington, DC; 2014.

15. Penrod JD, Deb P, Dellenbaugh C, et al. Hospital-based palliative care consultation: effects on hospital cost. J Palliat Med. 2010 Aug;13(8):973-9. Resumo

16. Ravakhah K, Chideme-Munodawafa A, Nakagawa S. Financial outcomes of palliative care services in an intensive care unit. J Palliat Med. 2010 Jan;13(1):7. Resumo

17. Morrison RS, Penrod JD, Cassel JB, et al. Cost savings associated with US hospital palliative care consultation programs. Arch Intern Med. 2008 Sep 8;168(16):1783-90.Texto completo  Resumo

18. Gade G, Venohr I, Conner D, et al. Impact of an inpatient palliative care team: a randomized controlled trial. J Palliat Med. 2008 Mar;11(2):180-90. Resumo

19. Bendaly EA, Groves J, Juliar B, et al. Financial impact of palliative care consultation in a public hospital. J Palliat Med. 2008 Dec;11(10):1304-8. Resumo

20. Ciemins EL, Blum L, Nunley M, et al. The economic and clinical impact of an inpatient palliative care consultation service: a multifaceted approach. J Palliat Med. 2007 Dec;10(6):1347-55. Resumo

21. Khandelwal N, Kross EK, Engelberg RA, et al. Estimating the effect of palliative care interventions and advance care planning on ICU utilization: a systematic review. Crit Care Med. 2015 May;43(5):1102-1.Texto completo  Resumo

22. Bainbridge D, Seow H, Sussman J. Common components of efficacious in-home end-of-life care programs: a review of systematic reviews. J Am Geriatr Soc. 2016 Mar;64(3):632-9. Resumo

23. Curtis JR, Treece PD, Nielsen EL, et al. Randomized trial of communication facilitators to reduce family distress and intensity of end-of-life care. Am J Respir Crit Care Med. 2016 Jan 15;193(2):154-62.Texto completo  Resumo

24. Khandelwal N, Long AC, Lee RY, et al. Pragmatic methods to avoid intensive care unit admission when it does not align with patient and family goals. Lancet Respir Med. 2019 Jul;7(7):613-25.Texto completo  Resumo

25. Lilley EJ, Khan KT, Johnston FM, et al. Palliative care interventions for surgical patients: a systematic review. JAMA Surg. 2016 Feb;151(2):172-83. Resumo

26. Bakitas M, Lyons KD, Hegel MT, et al. Effects of a palliative care intervention on clinical outcomes in patients with advanced cancer: the Project ENABLE II randomized controlled trial. JAMA. 2009 Aug 19;302(7):741-9.Texto completo  Resumo

27. Gomes B, Calanzani N, Curiale V, et al. Effectiveness and cost-effectiveness of home palliative care services for adults with advanced illness and their caregivers. Cochrane Database Syst Rev. 2013 Jun 6;(6):CD007760.Texto completo  Resumo

28. Shepperd S, Gonçalves-Bradley DC, Straus SE, et al. Hospital at home: home-based end-of-life care. Cochrane Database Syst Rev. 2016 Feb 18;2(2):CD009231.Texto completo  Resumo

29. Agency for Healthcare Research and Quality. Home-based primary care interventions. 2016 [internet publication].Texto completo

30. Temel JS, Greer JA, Muzikansky A, et al. Early palliative care for patients with metastatic non-small-cell lung cancer. N Engl J Med. 2010 Aug 19;363(8):733-42. Resumo

31. Bakitas MA, Tosteson TD, Li Z, et al. Early versus delayed initiation of concurrent palliative oncology care: patient outcomes in the ENABLE III randomized controlled trial. J Clin Oncol. 2015 May 1;33(13):1438-45. Resumo

32. Vanbutsele G, Pardon K, Van Belle S, et al. Effect of early and systematic integration of palliative care in patients with advanced cancer: a randomised controlled trial. Lancet Oncol. 2018 Mar;19(3):394-404. Resumo

33. Peppercorn JM, Smith TJ, Helft PR, et al. American Society of Clinical Oncology statement: toward individualized care for patients with advanced cancer. J Clin Oncol. 2011 Feb 20;29(6):755-60.Texto completo  Resumo

34. Glare PA. Early implementation of palliative care can improve patient outcomes. J Natl Compr Canc Netw. 2013 Mar;11 Suppl 1:S3-9.Texto completo  Resumo

35. Shaw KL, Clifford C, Thomas K, et al. Review: improving end-of-life care: a critical review of the gold standards framework in primary care. Palliat Med. 2010 Apr;24(3):317-29. Resumo

36. Christakis NA, Lamont EB. Extent and determinants of error in doctors' prognoses in terminally ill patients: prospective cohort study. BMJ. 2000 Feb 19;320(7233):469-72.Texto completo  Resumo

37. Weeks JC, Cook EF, O'Day SJ, et al. Relationship between cancer patients' predictions of prognosis and their treatment preferences. JAMA. 1998 Jun 3;279(21):1709-14.Texto completo  Resumo

38. Finlayson CS, Chen YT, Fu MR. The impact of patients' awareness of disease status on treatment preferences and quality of life among patients with metastatic cancer: a systematic review from 1997-2014. J Palliat Med. 2015 Feb;18(2):176-86. Resumo

39. Institute for Clinical Systems Improvement. Health care guideline: palliative care. November 2013 [internet publication].Texto completo

40. Moroni M, Zocchi D, Bolognesi D, et al. The 'surprise' question in advanced cancer patients: a prospective study among general practitioners. Palliat Med. 2014 Jul;28(7):959-64. Resumo

41. Moss AH, Lunney JR, Culp S, et al. Prognostic significance of the "surprise" question in cancer patients. J Palliat Med. 2010 Jul;13(7):837-40. Resumo

42. Downar J, Goldman R, Pinto R, et al. The “surprise question” for predicting death in seriously ill patients: a systematic review and meta-analysis. CMAJ. 2017 Apr 3;189(13):E484-93.Texto completo  Resumo

43. Education for Physicians on End-of-life Care (EPEC). Trainer's guide, module 2. Princeton, NJ: The Robert Wood Johnson Foundation; 1999.

44. Knaus WA, Harrell FE, Lynn J, et al. The SUPPORT prognostic model: objective estimates of survival for seriously ill hospitalized adults. Ann Intern Med. 1995 Feb 1;122(3):191-203. Resumo

45. Lau F, Downing GM, Lesperance M, et al. Use of palliative performance scale in end-of-life prognostication. J Palliat Med. 2006 Oct;9(5):1066-75. Resumo

46. Olajide O, Hanson L, Usher BM, et al. Validation of the palliative performance scale in the acute tertiary care hospital setting. J Palliat Med. 2007 Feb;10(1):111-7. Resumo

47. Seow H, Barbera L, Dudgeon D, et al. The association of the palliative performance scale and hazard of death in an ambulatory cancer population. J Palliat Med. 2013 Feb;16(2):156-62. Resumo

48. Glare P, Virik K. Independent prospective validation of the PaP score in terminally ill patients referred to a hospital-based palliative medicine consultation service. J Pain Symptom Manage. 2001 Nov;22(5):891-8. Resumo

49. Glare P, Eychmueller S, Virik K, et al. The use of the palliative prognostic score in patients with diagnoses other than cancer. J Pain Symptom Manage. 2003 Oct;26(4):883-5. Resumo

50. Inouye SK, Peduzzi PN, Robison JT, et al. Importance of functional measures in predicting mortality among older hospitalized patients. JAMA. 1998 Apr 15;279(15):1187-93.Texto completo  Resumo

51. Fischer SM, Gozansky WS, Sauaia A, et al. A practical tool to identify patients who may benefit from a palliative approach: the CARING criteria. J Pain Symptom Manage. 2006 Apr;31(4):285-92. Resumo

52. Youngwerth J, Min SJ, Statland B, et al. Caring about prognosis: a validation study of the caring criteria to identify hospitalized patients at high risk for death at 1 year. J Hosp Med. 2013 Dec;8(12):696-701. Resumo

53. Glare PA, Sinclair CT. Palliative medicine review: prognostication. J Palliat Med. 2008 Jan-Feb;11(1):84-103. Resumo

54. Bernacki RE, Block SD; American College of Physicians High Value Care Task Force. Communication about serious illness care goals: a review and synthesis of best practices. JAMA Intern Med. 2014 Dec;174(12):1994-2003. Resumo

55. Education for Physicians on End-of-life Care (EPEC). Trainer's guide, module 7. Princeton, NJ: The Robert Wood Johnson Foundation; 1999.

56. Kaldjian LC, Curtis AE, Shinkunas LA, et al. Goals of care toward the end of life: a structured literature review. Am J Hosp Palliat Care. 2014 Dec;174(12):1994-2003. Resumo

57. Johnston B, Larkin P, Connolly M, et al. Dignity-conserving care in palliative care settings: an integrative review. J Clin Nurs. 2015 Jul;24(13-14):1743-72. Resumo

58. Royal College of Physicians. Talking about dying: How to begin honest conversations about what lies ahead. Oct 2018 [internet publication].Texto completo

59. Education for Physicians on End-of-life Care (EPEC). Trainer's guide, module 3. Princeton, NJ: The Robert Wood Johnson Foundation; 1999.

60. Murray SA, Kendall M, Boyd K, et al. Illness trajectories and palliative care. BMJ. 2005 Apr 30;330(7498):1007-11. Resumo

61. Janssen DJ, Spruit MA, Wouters EF, et al. Daily symptom burden in end-stage chronic organ failure: a systematic review. Palliat Med. 2008 Dec;22(8):938-48. Resumo

62. Porter S, Knight CF, Schonwetter RS. Pocket guide to hospice/palliative medicine. Glenview, IL: American Academy of Hospice and Palliative Medicine; 2003:57-97.

63. Hjermstad MJ, Gibbins J, Haugen DF, et al. Pain assessment tools in palliative care: an urgent need for consensus. Palliat Med. 2008 Dec;22(8):895-903. Resumo

64. Youngwerth J, Johnson D. Palliative care: management of common physical and psychological symptoms. In: Glasheen JJ, ed. Hospital medicine secrets. Philadelphia, PA: Elsevier; 2007:612-8.

65. Thomas JR, von Gunten CF. Clinical management of dyspnoea. Lancet Oncol. 2002 Apr;3(4):223-8. Resumo

66. Panchal SJ, Muller-Schwefe J, Wurzelmann JI. Opioid-induced bowel dysfunction: prevalence, pathophysiology and burden. Int J Clin Pract. 2007 Jul;61(7):1181-7.Texto completo  Resumo

67. Miovic M, Block S. Psychiatric disorders in advanced cancer. Cancer. 2007 Oct 15;110(8):1665-76.Texto completo  Resumo

68. Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 2003 Jan;17(1):40-3. Resumo

69. Lloyd-Williams M, Spiller J, Ward J. Which depression screening tools should be used in palliative care? Palliat Med. 2003 Jan;17(1):40-3. Resumo

70. Horne-Thompson A, Grocke D. The effect of music therapy on anxiety in patients who are terminally ill. J Palliat Med. 2008 May;11(4):582-90. Resumo

71. Yennurajalingam S, Bruera E. Palliative management of fatigue at the close of life. JAMA. 2007 Jan 17;297(3):295-304. Resumo

72. Del Fabbro E, Dalal S, Bruera E. Symptom control in palliative care - part II: cachexia/anorexia and fatigue. J Palliat Med. 2006 Apr;9(2):409-21. Resumo

73. Krupp LB, LaRocca NG, Muir-Nash J, et al. The Fatigue Severity Scale. Application to patients with multiple sclerosis and systemic lupus erythematosus. Arch Neurol. 1989 Oct;46(10):1121-3. Resumo

74. Yavuzsen T, Davis MP, Walsh D, et al. Systematic review of the treatment of cancer-associated anorexia and weight loss. J Clin Oncol. 2005 Nov 20;23(33):8500-11. Resumo

75. Vaurio LE, Sands LP, Wang Y, et al. Postoperative delirium: the importance of pain and pain management. Anesth Analg. 2006 Apr;102(4):1267-73.Texto completo  Resumo

76. Morrison RS, Magaziner J, Gilbert M, et al. Relationship between pain and opioid analgesics on the development of delirium following hip fractures. J Gerontol A Biol Sci Med Sci. 2003 Jan;58(1):76-81. Resumo

77. Salluh JI, Wang H, Schneider EB, et al. Outcome of delirium in critically ill patients: systematic review and meta-analysis. BMJ. 2015 Jun 3;350:h2538.Texto completo  Resumo

78. Hosie A, Agar M, Lobb E, et al. Improving delirium recognition and assessment for people receiving inpatient palliative care: a mixed methods meta-synthesis. Int J Nurs Stud. 2017 Oct;75:123-9. Resumo

79. Solano JP. A comparison of symptom prevalence in far advanced cancer, AIDS, heart disease, chronic obstructive pulmonary disease and renal disease. J Pain Symptom Manage. 2006 Jan;31(1):58-69. Resumo

80. Morin L, Todd A, Barclay S, et al. Preventive drugs in the last year of life of older adults with cancer: Is there room for deprescribing? Cancer. 2019 Jul 1;125(13):2309-17.Texto completo  Resumo

81. AGS Panel on Persistent Pain in Older Persons. The management of persistent pain in older persons. J Am Geriatr Soc. 2002 Jun;50(6 Suppl):S205-2. Resumo

82. Knudsen AK, Aass N, Fainsinger R, et al. Classification of pain in cancer patients: a systematic literature review. Palliat Med. 2009 Jun;23(4):295-308. Resumo

83. American Pain Society. Pain: current understanding of assessment, management, and treatments. 2012 [internet publication].Texto completo

84. Furlan AD, Sandoval JA, Mailis-Gagnon A, et al. Opioids for chronic noncancer pain: a meta-analysis of effectiveness and side effects. CMAJ. 2006 May 23;174(11):1589-94.Texto completo  Resumo

85. Selecky PA, Eliasson Col. AH, Hall RI, et al. Palliative and end-of-life care for patients with cardiopulmonary diseases: American College of Chest Physicians position statement. Chest. 2006 May 23;174(11):1589-94. Resumo

86. Kalso E, Edwards JE, Moore RA, et al. Opioids in chronic non-cancer pain: a systematic review of efficacy and safety. Pain. 2004 Dec;112(3):372-80. Resumo

87. Busse JW, Wang L, Kamaleldin M, et al. Opioids for chronic noncancer pain: a systematic review and meta-analysis. JAMA. 2018 Dec 18;320(23):2448-60.Texto completo  Resumo

88. McNicol ED, Midbari A, Eisenberg E. Opioids for neuropathic pain. Cochrane Database Syst Rev. 2013 Aug 29;2013(8):CD006146.Texto completo  Resumo

89. Quigley C. The role of opioids in cancer pain. BMJ. 2005 Oct 8;331(7520):825-9. Resumo

90. Finnerup NB, Attal N, Haroutounian S, et al. Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis. Lancet Neurol. 2015 Feb;14(2):162-73. Resumo

91. National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: adult cancer pain [internet publication].Texto completo

92. Dalton JA, Keefe FJ, Carlson J, et al. Tailoring cognitive-behavioral treatment for cancer pain. Pain Manag Nurs. 2004 Mar;5(1):3-18. Resumo

93. Given C, Given B, Rahbar M, et al. Effect of a cognitive behavioral intervention on reducing symptom severity during chemotherapy. J Clin Oncol. 2004 Feb 1;22(3):507-16. Resumo

94. Bardia A, Barton DL, Prokop LJ, et al. Efficacy of complementary and alternative medicine therapies in relieving cancer pain: a systematic review. J Clin Oncol. 2006 Dec 1;24(34):5457-64. Resumo

95. Bradt J, Dileo C, Magill L, et al. Music interventions for improving psychological and physical outcomes in cancer patients. Cochrane Database Syst Rev. 2016 Aug 15;(8):CD006911.Texto completo  Resumo

96. Ernst E. Massage therapy for cancer palliation and supportive care: a systematic review of randomised clinical trials. Support Care Cancer. 2009 Apr;17(4):333-7. Resumo

97. Wilkinson S, Lockhart E, Gambles M, et al. Reflexology for symptom relief in patients with cancer. Cancer Nurs. 2008 Sep-Oct;31(5):354-60. Resumo

98. Guidelines and Audit Implementation Network. General palliative care guidelines for the management of pain at the end of life in adult patients. February 2011 [internet publication].Texto completo

99. Gutgsell KJ, Schluchter M, Margevicius S, et al. Music therapy reduces pain in palliative care patients: a randomized controlled trial. J Pain Symptom Manage. 2013 May;45(5):822-31. Resumo

100. Mao JJ, Ismaila N, Bao T, et al. Integrative Medicine for Pain Management in Oncology: Society for Integrative Oncology-ASCO Guideline. J Clin Oncol. 2022 Dec 1;40(34):3998-4024.Texto completo  Resumo

101. Levy MH. Pharmacologic treatment of cancer pain. N Engl J Med. 1996 Oct 10;335(15):1124-32. Resumo

102. Caraceni A, Hanks G, Kaasa S, et al; European Palliative Care Research Collaborative (EPCRC), European Association for Palliative Care (EAPC). Use of opioid analgesics in the treatment of cancer pain: evidence-based recommendations from the EAPC. Lancet Oncol. 2012 Feb;13(2):e58-68. Resumo

103. Caraceni A, Pigni A, Brunelli C. Is oral morphine still the first choice opioid for moderate to severe cancer pain? A systematic review within the European Palliative Care Research Collaborative guidelines project. Palliat Med. 2011 Jul;25(5):402-9. Resumo

104. King SJ, Reid C, Forbes K, et al. A systematic review of oxycodone in the management of cancer pain. Palliat Med. 2011 Jul;25(5):454-70. Resumo

105. Schmidt-Hansen M, Bennett MI, Hilgart J. Oxycodone for cancer pain in adult patients. JAMA. 2015 Sep 22-29;314(12):1282-3. Resumo

106. Riley J, Branford R, Droney J, et al. Morphine or oxycodone for cancer-related pain? A randomized, open-label, controlled trial. J Pain Symptom Manage. 2015 Feb;49(2):161-72. Resumo

107. Flemming K. The use of morphine to treat cancer-related pain: a synthesis of quantitative and qualitative research. J Pain Symptom Manage. 2010 Jan;39(1):139-54. Resumo

108. LeBon B, Zeppetella G, Higginson IJ. Effectiveness of topical administration of opioids in palliative care: a systematic review. J Pain Symptom Manage. 2009 May;37(5):913-7. Resumo

109. Wiffen PJ, Wee B, Moore RA. Oral morphine for cancer pain. Cochrane Database Syst Rev. 2016 Apr 22;4(4):CD003868.Texto completo  Resumo

110. Education for Physicians on End-of-life Care (EPEC). Trainer's guide, module 4. Princeton, NJ: The Robert Wood Johnson Foundation; 1999.

111. Collaborative for REMS Education. Extended release/long acting opioids: achieving safe use while improving patient care. Collaborative for REMS Education CO*RE Seller: CORE Collaboration for REMS Education; 2013.

112. Ballantyne JC, Mao J. Opioid therapy for chronic pain. N Engl J Med. 2012 Feb;15(2):186-91. Resumo

113. Paice JA, Portenoy R, Lacchetti C, et al. Management of chronic pain in survivors of adult cancers: American Society of Clinical Oncology clinical practice guideline. J Clin Oncol. 2016 Sep 20;34(27):3325-45.Texto completo  Resumo

114. McPherson ML, Walker KA, Davis MP, et al. Safe and appropriate use of methadone in hospice and palliative care: expert consensus white paper. J Pain Symptom Manage. 2019 Mar;57(3):635-45.e4.Texto completo  Resumo

115. Kvale PA, Selecky PA, Prakash UB. Palliative care in lung cancer: ACCP evidence-based clinical practice guidelines. Chest. 2007 Sep;132(3 Suppl):368S-403S. Resumo

116. Librach SL, Bouvette M, De Angelis C, et al. Consensus recommendations for the management of constipation in patients with advanced, progressive illness. J Pain Symptom Manage. 2010 Nov;40(5):761-73. Resumo

117. Angst MS, Clark JD. Opioid-induced hyperalgesia. Anesthesiology. 2006 Mar;104(3):570-87. Resumo

118. Mercadante S, Bruera E. Opioid switching: a systematic and critical review. Cancer Treat Rev. 2006 Jun;32(4):304-15. Resumo

119. Mercadante S. Opioid rotation for cancer pain. Cancer. 1999 Nov 1;86(9):1856-66. Resumo

120. Gilron I, Bailey JM, Tu D, et al. Morphine, gabapentin, or their combination for neuropathic pain. N Engl J Med. 2005 Mar 31;352(13):1324-34.Texto completo  Resumo

121. Smith EM, Pang H, Cirrincione C, et al; Alliance for Clinical Trials in Oncology. Effect of duloxetine on pain, function, and quality of life among patients with chemotherapy-induced painful peripheral neuropathy: a randomized clinical trial. JAMA. 2013 Apr 3;309(13):1359-67. Resumo

122. Bauman G, Charette M, Reid R, et al. Radiopharmaceuticals for the palliation of painful metastasis - a systematic review. Radiother Oncol. 2005 Jun;75(3):258-70. Resumo

123. Serafini AN. Therapy of metastatic bone pain. J Nucl Med. 2001 Jun;42(6):895-906.Texto completo  Resumo

124. Wong R, Wiffen PJ. Bisphosphonates for the relief of pain secondary to bone metastasis. Cochrane Database Syst Rev. 2002;2002(2):CD002068.Texto completo  Resumo

125. Macherey S, Monsef I, Jahn F, et al. Bisphosphonates for advanced prostate cancer. Cochrane Database Syst Rev. 2017 Dec 26;(12):CD006250.Texto completo  Resumo

126. O'Carrigan B, Wong MH, Willson ML, et al. Bisphosphonates and other bone agents for breast cancer. Cochrane Database Syst Rev. 2017 Oct 30;(10):CD003474.Texto completo  Resumo

127. Sze WM, Shelley M, Held I, et al. Palliation of metastatic bone pain: single fraction versus multifraction radiotherapy. Cochrane Database Syst Rev. 2004;2002(2):CD004721.Texto completo  Resumo

128. Lutz S, Balboni T, Jones J, et al. Palliative radiation therapy for bone metastases: Update of an ASTRO Evidence-Based Guideline. Pract Radiat Oncol. 2017 Jan - Feb;7(1):4-12.Texto completo  Resumo

129. Martinez-Zapata MJ, Roqué i Figuls M, Alonso-Coello P, et al. Calcitonin for metastatic bone pain. Cochrane Database Syst Rev. 2006 Jul 19;(3):CD003223.Texto completo  Resumo

130. Fallon M, Hoskin PJ, Colvin LA, et al. Randomized double-blind trial of pregabalin versus placebo in conjunction with palliative radiotherapy for cancer-induced bone pain. J Clin Oncol. 2016 Feb 20;34(6):550-6.Texto completo  Resumo

131. Chow E, Harris K, Fan G, et al. Palliative radiotherapy trials for bone metastases: a systematic review. J Clin Oncol. 2007 Apr 10;25(11):1423-36. Resumo

132. Meeuse JJ, van der Linden YM, van Tienhoven G, et al. Efficacy of radiotherapy for painful bone metastases during the last 12 weeks of life: results from the Dutch Bone Metastasis Study. Cancer. 2010 Jun 1;116(11):2716-25.Texto completo  Resumo

133. Dennis K, Makhani L, Zeng L, et al. Single fraction conventional external beam radiation therapy for bone metastases: a systematic review of randomised controlled trials. Radiother Oncol. 2013 Jan;106(1):5-14. Resumo

134. Qaseem A, Snow V, Shekelle P, et al. Evidence-based interventions to improve the palliative care of pain, dyspnea, and depression at the end of life: a clinical practice guideline from the American College of Physicians. Ann Intern Med. 2008 Jan 15;148(2):141-6.Texto completo  Resumo

135. Lorenz KA, Lynn J, Dy SM, et al. Evidence for improving palliative care at the end of life: a systematic review. Ann Intern Med. 2008 Jan 15;148(2):147-59. Resumo

136. O'Connor AB, Dworkin RH. Treatment of neuropathic pain: an overview of recent guidelines. Am J Med. 2009 Oct;122(10 Suppl):S22-32. Resumo

137. Hui D, Bohlke K, Bao T, et al. Management of dyspnea in advanced cancer: ASCO guideline. J Clin Oncol. 2021 Apr 20;39(12):1389-411. Resumo

138. Jennings AL, Davies AN, Higgins JP, et al. A systematic review of the use of opioids in the management of dyspnoea. Thorax. 2002 Nov;57(11):939-44.Texto completo  Resumo

139. Johnson MJ, Hui D, Currow DC. Opioids, exertion, and dyspnea: a review of the evidence. Am J Hosp Palliat Care. 2016 Mar;33(2):194-200. Resumo

140. Ben-Aharon I, Gafter-Gvili A, Paul A, et al. Interventions for alleviating cancer-related dyspnea: a systematic review. J Clin Oncol. 2008 May 10;26(14):2396-404. Resumo

141. Viola R, Kiteley C, Lloyd NS, et al. The management of dyspnea in cancer patients: a systematic review. Support Care Cancer. 2008 Apr;16(4):329-37. Resumo

142. Barnes H, McDonald J, Smallwood N, et al. Opioids for the palliation of refractory breathlessness in adults with advanced disease and terminal illness. Cochrane Database Syst Rev. 2016 Mar 31;3(3):CD011008.Texto completo  Resumo

143. Polosa R, Simidchiev A, Walters EH. Nebulised morphine for severe interstitial lung disease. Cochrane Database Syst Rev. 2002 Jul 22;(3):CD002872. Resumo

144. Booth S, Anderson H, Swannick M, et al. The use of oxygen in the palliation of breathlessness. A report of the expert working group of the Scientific Committee of the Association of Palliative Medicine. Respir Med.2004 Jan;98(1):66-77. Resumo

145. Abernethy AP, Currow DC, Frith P, et al. Randomised, double blind, placebo controlled crossover trial of sustained release morphine for the management of refractory dyspnoea. BMJ. 2003 Sep 6;327(7414):523-8.Texto completo  Resumo

146. Philip J, Gold M, Milner A, et al. A randomized, double-blind, crossover trial of the effect of oxygen on dyspnea in patients with advanced cancer. J Pain Symptom Manage. 2006 Dec;32(6):541-50. Resumo

147. Abernethy AP, McDonald CF, Frith PA, et al. Effect of palliative oxygen versus room air in relief of breathlessness in patients with refractory dyspnoea: a double-blind, randomised controlled trial. Lancet. 2010 Sep 4;376(9743):784-93.Texto completo  Resumo

148. Bruera E, Sweeney C, Willey J, et al. A randomized controlled trial of supplemental oxygen versus air in cancer patients with dyspnea. Palliat Med. 2003 Dec;17(8):659-63. Resumo

149. Ameer F, Carson KV, Usmani ZA, et al. Ambulatory oxygen for people with chronic obstructive pulmonary disease who are not hypoxaemic at rest. Cochrane Database Syst Rev. 2014 Jun 24;2014(6):CD000238.Texto completo  Resumo

150. Hui D, Kilgore K, Frisbee-Hume S, et al. Dexamethasone for dyspnea in cancer patients: a pilot double-blind, randomized, controlled trial. J Pain Symptom Manage. 2016 Jul;52(1):8-16.e1. Resumo

151. Man GC, Hsu K, Sproule BJ. Effect of alprazolam on exercise and dyspnea in patients with chronic obstructive pulmonary disease. Chest. 1986 Dec;90(6):832-6. Resumo

152. Simon ST, Higginson IJ, Booth S, et al. Benzodiazepines for the relief of breathlessness in advanced malignant and non-malignant diseases in adults. Cochrane Database Syst Rev. 2016 Oct 20;10(10):CD007354.Texto completo  Resumo

153. Navigante AH, Cerchietti LCA, Castro MA, et al. Midazolam as adjunct therapy to morphine in the alleviation of severe dyspnea perception in patients with advanced cancer. J Pain Symptom Manage. 2006 Jan;31(1):38-47. Resumo

154. Bausewein C, Booth S, Gysels M, et al. Non-pharmacological interventions for breathlessness in advanced stages of malignant and non-malignant diseases. Cochrane Database Syst Rev. 22008 Apr 16;(2):CD005623.Texto completo  Resumo

155. Clemens KE, Quednau I, Klaschik E. Is there a higher risk of respiratory depression in opioid-naive palliative care patients during symptomatic therapy of dyspnea with strong opioids? J Palliat Med. 2008 Mar;11(2):204-16. Resumo

156. Chan JD, Treece PD, Engelberg RA, et al. Narcotic and benzodiazepine use after withdrawal of life support: association with time to death? Chest. 2004 Jul;126(1):286-93. Resumo

157. Goodheart CR, Leavitt SB. Pain treatment topics: managing opioid-induced constipation in ambulatory-care patients. August 2006 [internet publication].Texto completo

158. Larkin PJ, Sykes NP, Centeno C, et al. The management of constipation in palliative care: clinical practice recommendations. Palliat Med. 2008 Oct;22(7):796-807. Resumo

159. Candy B, Jones L, Larkin PJ, et al. Laxatives for the management of constipation in people receiving palliative care. Cochrane Database Syst Rev. 2015 May 13;2015(5):CD003448.Texto completo  Resumo

160. Klaschik E, Nauck F, Ostgathe C. Constipation - modern laxative therapy. Support Care Cancer. 2003 Nov;11(11):679-85. Resumo

161. Education for Physicians on End-of-life Care (EPEC). Trainer's guide, module 10. Princeton, NJ: The Robert Wood Johnson Foundation; 1999.

162. Wood GJ, Shega JW, Lynch B, et al. Management of intractable nausea and vomiting in patients at the end of life. JAMA. 2007 Sep 12;298(10):1196-207. Resumo

163. Hawley PH, Byeon JJ. A comparison of sennosides-based bowel protocols with and without docusate in hospitalized patients with cancer. J Palliat Med. 2008 Oct;22(7):796-807. Resumo

164. Tarumi Y, Wilson MP, Szafran O, et al. Randomized, double-blind, placebo-controlled trial of oral docusate in the management of constipation in hospice patients. J Pain Symptom Manage. 2013 Jan;45(1):2-13.Texto completo  Resumo

165. Hurdon V, Viola R, Schroder C. How useful is docusate in patients at risk for constipation? A systematic review of the evidence in the chronically ill. J Pain Symptom Manage. 2000 Feb;19(2):130-6. Resumo

166. Thomas J, Karver S, Cooney GA, et al. Methylnaltrexone for opioid-induced constipation in advanced illness. N Engl J Med. 2008 May 29;358(22):2332-43.Texto completo  Resumo

167. Chamberlain BH, Cross K, Winston JL, et al. Methylnaltrexone treatment of opioid-induced constipation in patients with advanced illness. J Pain Symptom Manage. 2009 Nov;38(5):683-90. Resumo

168. Ndefo UA, Erowele GI. Focus on methylnaltrexone: a selective mu-opioid receptor antagonist for the treatment of opioid-induced constipation. J Pharm Technol. 2011;27:15-8.

169. Candy B, Jones L, Vickerstaff V, et al. Mu-opioid antagonists for opioid-induced bowel dysfunction in people with cancer and people receiving palliative care. Cochrane Database Syst Rev. 2018 Jun 5;(6):CD006332.Texto completo  Resumo

170. Morrison RS, Meier DE. Palliative care. N Engl J Med. 2004 Jun 17;350(25):2582-90. Resumo

171. Ly KL, Chidgey J, Addington-Hall J, et al. Depression in palliative care: a systematic review. Part 2. Treatment. Palliat Med. 2002 Jul;16(4):279-84. Resumo

172. Education for Physicians on End-of-life Care (EPEC). Trainer's guide, module 6. Princeton, NJ: The Robert Wood Johnson Foundation; 1999.

173. Ream E, Richardson A, Expander-Dann C. Supportive intervention for fatigue in patients undergoing chemotherapy: a randomized controlled trial. J Pain Symptom Manage. 2006 Feb;31(2):148-61. Resumo

174. Dileo C. Effects of music and music therapy on medical patients: a meta-analysis of the research and implications for the future. J Soc Integr Oncol. 2006 Spring;4(2):67-70. Resumo

175. Maratos A, Gold C, Wang X, et al. Music therapy for depression. Cochrane Database Syst Rev. 2008 Jan 23;(1):CD004517.Texto completo  Resumo

176. Andersen BL, DeRubeis RJ, Berman BS, et al. Screening, assessment, and care of anxiety and depressive symptoms in adults with cancer: an American Society of Clinical Oncology guideline adaptation. J Clin Oncol. 2014 May 20;32(15):1605-19.Texto completo  Resumo

177. Unutzer JN. Late-life depression. N Engl J Med. 2007 Nov 29;357(22):2269-76. Resumo

178. Ostuzzi G, Matcham F, Dauchy S, et al. Antidepressants for the treatment of depression in people with cancer. Cochrane Database Syst Rev. 2018 Apr 23;(4):CD011006.Texto completo  Resumo

179. Li M, Fitzgerald P, Rodin G. Evidence-based treatment of depression in patients with cancer. J Clin Oncol. 2012 Apr 10;30(11):1187-96. Resumo

180. Rodin G, Lloyd N, Katz M, et al. The treatment of depression in cancer patients: a systematic review. Support Care Cancer. 2007 Feb;15(2):123-36. Resumo

181. Candy B, Jones L, Williams R, et al. Psychostimulants for depression. Cochrane Database Syst Rev. 2008 Apr 16;(2):CD006722.Texto completo  Resumo

182. Rayner L, Price A, Evans A, et al. Antidepressants for the treatment of depression in palliative care: systematic review and meta-analysis. Palliat Med. 2011 Mar;47(5):702-12. Resumo

183. Periyakoil VS, Skultety K, Sheikh J. Panic, anxiety, and chronic dyspnea. J Palliat Med. 2005 Apr;8(2):453-9. Resumo

184. Thekkumpurath P, Venkateswaran C, Kumar M, et al. Screening for psychological distress in palliative care: a systematic review. J Pain Symptom Manage. 2008 Nov;36(5):520-8. Resumo

185. Salt S, Mulvaney CA, Preston NJ. Drug therapy for symptoms associated with anxiety in adult palliative care patients. Cochrane Database Syst Rev. 2017 May 18;(5):CD004596.Texto completo  Resumo

186. Nübling G, Allmendinger S, Lorenzl S. Drug therapy of anxiety and fear in palliative care patients with cancer or other illnesses: a systematic review [in German]. Schmerz. 2012 Sep;26(5):537-49. Resumo

187. Sood A, Barton DL, Bauer BA, et al. A critical review of complementary therapies for cancer-related fatigue. Integr Cancer Ther. 2007 Mar;6(1):8-13. Resumo

188. Strasser F, Luftner D, Possinger K, et al. Comparison of orally administered cannabis extract and delta-9-tetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, Phase III, randomized, double-blind, placebo-controlled clinical trial from the Cannabis-In-Cachexia-Study-Group. J Clin Oncol. 2006 Jul 20;24(21):3394-400. Resumo

189. Cramp F, Byron-Daniel J. Exercise for the management of cancer-related fatigue in adults. Cochrane Database Syst Rev. 2012 Nov 14;(11):CD006145. Resumo

190. Lowe SS, Watanabe SM, Courneya KS. Physical activity as a supportive care intervention in palliative cancer patients: a systematic review. J Support Oncol. 2009 Jan-Feb;7(1):27-34. Resumo

191. Goedendorp MM, Knoop H, Gielissen MF, et al. The effects of cognitive behavioral therapy for postcancer fatigue on perceived cognitive disabilities and neuropsychological test performance. J Pain Symptom Manage. 2014 Jan;47(1):35-44. Resumo

192. Mustian KM, Alfano CM, Heckler C, et al. Comparison of pharmaceutical, psychological, and exercise treatments for cancer-related fatigue: a meta-analysis. JAMA Oncol. 2017 Jul 1;3(7):961-8.Texto completo  Resumo

193. National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: cancer-related fatigue [internet publication].Texto completo

194. Minton O, Richardson A, Sharpe M, et al. Drug therapy for the management of cancer related fatigue. Cochrane Database Syst Rev. 2010 Jul 7;(7):CD006704. Resumo

195. Minton O, Richardson A, Sharpe M, et al. Psychostimulants for the management of cancer-related fatigue: a systematic review and meta-analysis. J Pain Symptom Manage. 2011 Apr;41(4):761-7. Resumo

196. Mücke M, Mochamat M, Cuhls H, et al. Pharmacological treatments for fatigue associated with palliative care. Cochrane Database Syst Rev. 2015 May 30;2015(5):CD006788.Texto completo  Resumo

197. Moraska AR, Sood A, Dakhil SR, et al. Phase III, randomized, double-blind, placebo-controlled study of long-acting methylphenidate for cancer-related fatigue: North Central Cancer Treatment Group NCCTG-N05C7 Trial. J Clin Oncol. 2010 Aug 10;28(23):3673-9. Resumo

198. Yennurajalingam S, Frisbee-Hume S, Palmer JL, et al. Reduction of cancer-related fatigue with dexamethasone: a double-blind, randomized, placebo-controlled trial in patients with advanced cancer. J Clin Oncol. 2013 Sep 1;31(25):3076-82. Resumo

199. Ruiz Garcia V, López-Briz E, Carbonell Sanchis R, et al. Megestrol acetate for treatment of anorexia-cachexia syndrome. Cochrane Database Syst Rev. 2013 Mar 28;2013(3):CD004310.Texto completo  Resumo

200. Bodenner D, Spencer T, Riggs AT, et al. A retrospective study of the association between megestrol acetate administration and mortality among nursing home residents with clinically significant weight loss. Am J Geriatr Pharmacother. 2007 Jun;5(2):137-46. Resumo

201. Miller S, McNutt L, McCann MA, et al. Use of corticosteroids for anorexia in palliative medicine: a systematic review. J Palliat Med. 2014 Apr;17(4):482-5. Resumo

202. Dewey A, Baughan C, Dean T, et al. Eicosapentaenoic acid (EPA, an omega-3 fatty acid from fish oils) for the treatment of cancer cachexia. Cochrane Database Syst Rev. 2007 Jan 24;2007(1):CD004597. Resumo

203. Koretz RL, Avenell A, Lipman TO, et al. Does enteral nutrition affect clinical outcome? A systematic review of the randomized trials. Am J Gastroenterol. 2007 Feb;102(2):412-29. Resumo

204. Dy SM. Enteral and parenteral nutrition in terminally ill cancer patients: a review of the literature. Am J Hosp Palliat Care. 2006 Oct-Nov;23(5):369-77. Resumo

205. Buchan EJ, Haywood A, Syrmis W, et al. Medically assisted hydration for adults receiving palliative care. Cochrane Database Syst Rev. 2023 Jun 21;(8):CD006273.Texto completo

206. Bruera E, Hui D, Dalal S, et al. Parenteral hydration in patients with advanced cancer: a multicenter, double-blind, placebo-controlled randomized trial. J Clin Oncol. 2013 Jan 1;31(1):111-8.Texto completo  Resumo

207. Sampson EL, Candy B, Jones L. Enteral tube feeding for older people with advanced dementia. Cochrane Database Syst Rev. 2009 Apr 15;2009(2):CD007209. Resumo

208. Sanders DS, Carter MJ, D'Silva J, et al. Survival analysis in percutaneous endoscopic gastrostomy feeding: a worse outcome in patients with dementia. Am J Gastroenterol. 2000 Jun;95(6):1472-5. Resumo

209. Murphy LM, Lipman TO. Percutaneous endoscopic gastrostomy does not prolong survival in patients with dementia. Arch Intern Med. 2003 Jun 9;163(11):1351-3.Texto completo  Resumo

210. American Geriatrics Society Ethics Committee and Clinical Practice and Models of Care Committee. American Geriatrics Society feeding tubes in advanced dementia position statement. J Am Geriatr Soc. 2014 Aug;62(8):1590-3.Texto completo  Resumo

211. Casarett DJ, Inouye SK. Diagnosis and management of delirium near the end of life. Ann Intern Med. 2001 Jul 3;135(1):32-40. Resumo

212. Young J, Inouye SK. Delirium in older people. BMJ. 2007 Apr 21;334(7598):842-6. Resumo

213. Martinez F, Tobar C, Hill N. Preventing delirium: should non-pharmacological, multicomponent interventions be used? A systematic review and meta-analysis of the literature. Age Ageing. 2015 Mar;44(2):196-204.Texto completo  Resumo

214. Candy B, Jackson KC, Jones L, et al. Drug therapy for delirium in terminally ill adult patients. Cochrane Database Syst Rev. 2012 Nov 14;(11):CD004770. Resumo

215. Crawford GB, Agar MM, Quinn SJ, et al. Pharmacovigilance in hospice/palliative care: net effect of haloperidol for delirium. J Palliat Med. 2013 Nov;16(11):1335-41. Resumo

216. Bush SH, Kanji S, Pereira JL, et al. Treating an established episode of delirium in palliative care: expert opinion and review of the current evidence base with recommendations for future development. J Pain Symptom Manage. 2014 Aug;48(2):231-48.Texto completo  Resumo

217. Agar MR, Lawlor PG, Quinn S, et al. Efficacy of oral risperidone, haloperidol, or placebo for symptoms of delirium among patients in palliative care: a randomized clinical trial. JAMA Intern Med. 2017 Jan 1;177(1):34-42. Resumo

218. Lonergan E, Britton AM, Luxenberg J, et al. Antipsychotics for delirium. Cochrane Database Syst Rev. 2007 Apr 18;(2):CD005594. Resumo

219. Schneider LS, Dagerman KS, Insel P. Risk of death with atypical antipsychotic drug treatment for dementia: meta-analysis of randomized placebo-controlled trials. JAMA. 2005 Oct 19;294(15):1934-43. Resumo

220. Wang PS, Schneeweiss S, Avorn J, et al. Risk of death in elderly users of conventional vs. atypical antipsychotic medications. N Engl J Med. 2005 Dec 1;353(22):2335-41.Texto completo  Resumo

221. Lonergan E, Luxenberg J, Sastre AA. Benzodiazepines for delirium. Cochrane Database Syst Rev. 2009 Oct 7;2009(4):CD006379. Resumo

222. Elie D, Gagnon P, Gagnon B, et al. Using psychostimulants in end-of-life patients with hypoactive delirium and cognitive disorders: a literature review [in French]. Can J Psych. 2010 Jun;55(6):386-93. Resumo

223. Ücok A, Gaebel W. Side effects of atypical antipsychotics: a brief overview. World Psychiatry. 2008 Feb;7(1):58-62.Texto completo  Resumo

224. Scorza K, Williams A, Phillips D, et al. Evaluation of nausea and vomiting. Am Fam Physician. 2007 Jul 1;76(1):76-84.Texto completo  Resumo

225. National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: antiemesis [internet publication].Texto completo

226. Mizukami N, Yamauchi M, Koike K, et al. Olanzapine for the prevention of chemotherapy-induced nausea and vomiting in patients receiving highly or moderately emetogenic chemotherapy: a randomized, double-blind, placebo-controlled study. J Pain Symptom Manage. 2014 Mar;47(3):542-50. Resumo

227. Navari RM, Qin R, Ruddy KJ, et al. Olanzapine for the prevention of chemotherapy-induced nausea and vomiting. N Engl J Med. 2016 Jul 14;375(2):134-42.Texto completo  Resumo

228. Sutherland A, Naessens K, Plugge E, et al. Olanzapine for the prevention and treatment of cancer-related nausea and vomiting in adults. Cochrane Database Syst Rev. 2018 Sep 21;(9):CD012555.Texto completo  Resumo

229. Benze G, Alt-Epping B, Geyer A, et al. Treatment of nausea and vomiting with prokinetics and neuroleptics in palliative care patients: a review [in German]. Schmerz. 2012 Sep;26(5):500-14. Resumo

230. To TH, Agar M, Yates P, et al. Prescribing for nausea in palliative care: a cross-sectional national survey of Australian palliative medicine doctors. J Palliat Med. 2014 Sep;17(9):1032-6. Resumo

231. Smith LA, Azariah F, Lavender VT, et al. Cannabinoids for nausea and vomiting in adults with cancer receiving chemotherapy. Cochrane Database Syst Rev. 2015 Nov 12;2015(11):CD009464.Texto completo  Resumo

232. Vayne-Bossert P, Haywood A, Good P, et al. Corticosteroids for adult patients with advanced cancer who have nausea and vomiting (not related to chemotherapy, radiotherapy, or surgery). Cochrane Database Syst Rev. 2017 Jul 3;(7):CD012002.Texto completo  Resumo

233. Murray-Brown F, Dorman S. Haloperidol for the treatment of nausea and vomiting in palliative care patients. Cochrane Database Syst Rev. 2015 Nov 2;2015(11):CD006271.Texto completo  Resumo

234. Smith TJ, Ritter JK, Poklis JL, et al. ABH gel is not absorbed from the skin of normal volunteers. J Pain Symptom Manage. 2012 May;43(5):961-6.Texto completo  Resumo

235. Weschules DJ. Tolerability of the compound ABHR in hospice patients. J Palliat Med. 2005 Dec;8(6):1135-43. Resumo

236. Tulsky JA. Beyond advanced directives: importance of communication skills at the end of life. JAMA. 2005 Jul 20;294(3):359-65. Resumo

237. Education for Physicians on End-of-life Care (EPEC) Trainer's guide, plenary 2. Princeton, NJ: The Robert Wood Johnson Foundation; 1999.

238. Lo B, Steinbrook R. Resuscitating advance directives. Arch Intern Med. 2004 Jul 26;164(14):1501-6. Resumo

239. Chittenden EH, Clark ST, Pantilat SZ. Discussing resuscitation preferences with patients: challenges and rewards. J Hosp Med. 2006 Jul;1(4):231-40. Resumo

240. Dow LA, Matsuyama RK, Ramakrishnan V, et al. Paradoxes in advance care planning: the complex relationship of oncology patients, their physicians, and advance medical directives. J Clin Oncol. 2010 Jan 10;28(2):299-304. Resumo

241. Detering KM, Hancock AD, Reade MC, et al. The impact of advance care planning on end of life care in elderly patients: randomised controlled trial. BMJ. 2010 Mar 23;340:c134.Texto completo  Resumo

242. Silveira MJ, Kim SY, Langa KM. Advance directives and outcomes of surrogate decision making before death. N Engl J Med. 2010 Apr 1;362(13):1211-8. Resumo

243. Abel J, Pring A, Rich A, et al. The impact of advance care planning of place of death, a hospice retrospective cohort study. BMJ Support Palliat Care. 2013 Jun;3(2):168-73.Texto completo  Resumo

244. Song MK, Ward SE, Fine JP, et al. Advance care planning and end-of-life decision making in dialysis: a randomized controlled trial targeting patients and their surrogates. Am J Kidney Dis. 2015 Nov;66(5):813-22. Resumo

245. POLST. Physician orders for life-sustaining treatment paradigm. 2012-2015 [internet publication].Texto completo

246. Hickman SE, Nelson CA, Perrin NA, et al. A comparison of methods to communicate treatment preferences in nursing facilities: traditional practices versus the Physician Orders for Life-Sustaining Treatment program. J Am Geriatr Soc. 2010 Jul;58(7):1241-8.Texto completo  Resumo

247. Hickman SE, Tolle SW, Brummel-Smith K, et al. Use of the Physician Orders for Life-Sustaining Treatment program in Oregon nursing facilities: beyond resuscitation status. J Am Geriatr Soc. 2004 Sep;52(9):1424-9. Resumo

248. Lee MA, Brummel-Smith K, Meyer J, et al. Physician Orders for Life-Sustaining Treatment (POLST): outcomes in a PACE program. J Am Geriatr Soc. 2000 Oct;48(10):1219-25. Resumo

249. Tolle SW, Tilden VP, Nelson CA, et al. A prospective study of the efficacy of the physician order form for life-sustaining treatment. J Am Geriatr Soc. 1998 Sep;46(9):1097-102. Resumo

250. Meyers JL, Moore C, McGrory A, et al. Physician Orders for Life-Sustaining Treatment form: honoring end-of-life directives for nursing home residents. J Gerontol Nurs. 2004 Sep;30(9):37-46. Resumo

251. Butler M, Ratner E, McCreedy E, et al. Decision aids for advance care planning: an overview of the state of the science. Ann Intern Med. 2014 Sep 16;161(6):408-18.Texto completo  Resumo

252. Sudore RL, Knight SJ, McMahan RD, et al. A novel website to prepare diverse older adults for decision making and advance care planning: a pilot study. J Pain Symptom Manage. 2014 Apr;47(4):674-86. Resumo

253. Van Scoy LJ, Reading JM, Scott AM, et al. Exploring the topics discussed during a conversation card game about death and dying: a content analysis. J Pain Symptom Manage. 2016 Nov;52(5):655-62. Resumo

254. Delgado-Guay MO, Rodriguez-Nunez A, De la Cruz V, et al. Advanced cancer patients' reported wishes at the end of life: a randomized controlled trial. Support Care Cancer. 2016 Oct;24(10):4273-81. Resumo

255. National Ethics Committee of the Veterans Health Administration. The ethics of palliative sedation as therapy of last resort. Am J Hosp Palliat Care. 2006 Dec-2007 Jan;23(6):483-91. Resumo

256. Carr MF, Mohr GJ. Palliative sedation as part of a continuum of palliative care. J Palliat Med. 2008 Jan-Feb;11(1):76-81. Resumo

257. De Graeff A, Dean M. Palliative sedation therapy in the last weeks of life: a literature review and recommendations for standards. J Palliat Med. 2007 Feb;10(1):67-85. Resumo

258. Kirk TW, Mahon MM. National Hospice and Palliative Care Organization (NHPCO) position statement and commentary on the use of palliative sedation in imminently dying terminally ill patients. J Pain Symptom Manage. 2010 May;39(5):914-23. Resumo

259. Bruce SD, Hendrix CC, Gentry JH. Palliative sedation in end-of-life care. J Hospice Palliat Nurs. 2006 Nov 1;8(6):320-7.

260. Claessens P, Menten J, Schotsmans P, et al. Palliative sedation: a review of the research literature. J Pain Symptom Manage. 2008 Sep;36(3):310-33. Resumo

261. Schildmann EK, Schildmann J, Kiesewetter I. Medication and monitoring in palliative sedation therapy: a systematic review and quality assessment of published guidelines. J Pain Symptom Manage. 2015 Apr;49(4):734-46. Resumo

262. Mercadante S, Intravaia G, Villari P, et al. Controlled sedation for refractory symptoms in dying patients. J Pain Symptom Manage. 2009 May;37(5):771-9. Resumo

263. Education for Physicians on End-of-life Care (EPEC). Trainer's guide, module 5. Princeton, NJ: The Robert Wood Johnson Foundation; 1999.

264. Scottish Palliative Care Guidelines. End of life care. December 2014 [internet publication].Texto completo

265. National Institute for Health and Care Excellence. End of life care for infants, children and young people with life-limiting conditions: planning and management. July 2019 [internet publication].Texto completo

266. National Institute for Health and Care Excellence. Palliative care for adults: strong opioids for pain relief. August 2016 [internet publication].Texto completo

267. European Society for Medical Oncology. ESMO Clinical Practice Guidelines on palliative care: supportive and palliative care. Ann Oncol. 2018 Jan 1;29(1):36-43.Texto completo

268. European Society for Medical Oncology (ESMO). Clinical Practice Guidelines on palliative care: advanced care planning. 2014 [internet publication].Texto completo

269. Crawford GB, Dzierżanowski T, Hauser K, et al. Care of the adult cancer patient at the end of life: ESMO Clinical Practice Guidelines. ESMO Open. 2021 Aug;6(4):100225.Texto completo  Resumo

270. National Institute for Health and Care Excellence. Care of dying adults in the last days of life. December 2015 [internet publication].Texto completo

271. Clayton JM, Hancock KM, Butow PN, et al. Clinical practice guidelines for communicating prognosis and end-of-life issues with adults in the advanced stages of a life-limiting illness, and their caregivers. Med J Aust. 2007 Jun 18;186(S12):S77-S105.Texto completo  Resumo

272. Giannini A, Messeri A, Aprile A, et al. End-of-life decisions in pediatric intensive care: recommendations of the Italian Society of Neonatal and Pediatric Anesthesia and Intensive Care (SARNePI). Paediatr Anaesth. 2008 Nov;18(11):1089-95. Resumo

273. Clinical Practice Guidelines and Protocols in British Columbia. Palliative care for the patient with incurable cancer or advanced disease - part 1: approach to care. February 2017 [internet publication].Texto completo

274. Gomm S, Farrington K; NHS Kidney Care, National End of Life Care Programme. End of life care in advanced kidney disease: a framework for implementation. June 2009 [internet publication].Texto completo

275. Green E, Zwaal C, Beals C, et al; Cancer Care Ontario. Cancer-related pain management: a report of evidence-based recommendations to guide practice. Clin J Pain. 2010 Jul-Aug;26(6):449-62. Resumo

276. Agnew A, Manktelow R, Taylor B, et al. Bereavement needs assessment in specialist palliative care: a review of the literature. Palliat Med. 2010 Jan;24(1):46-59. Resumo

277. Clayton JM, Hancock K, Parker S, et al. Sustaining hope when communicating with terminally ill patients and their families: a systematic review. Psychooncology. 2008 Jul;17(7):641-59. Resumo

278. National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: palliative care [internet publication].Texto completo

279. National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: distress management [internet publication].Texto completo

280. National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: survivorship [internet publication].Texto completo

281. Lanken PN, Terry PB, DeLisser HM, et al. An official American Thoracic Society clinical policy statement: palliative care for patients with respiratory diseases and critical illnesses. Am J Respir Crit Care Med. 2008 Apr 15;177(8):912-27.Texto completo  Resumo

282. Sullivan DR, Iyer AS, Enguidanos S, et al. Palliative care early in the care continuum among patients with serious respiratory illness: an official ATS/AAHPM/HPNA/SWHPN policy statement. Am J Respir Crit Care Med. 2022 Sep 15;206(6):e44-69.Texto completo  Resumo

283. Truog RD, Campbell ML, Curtis JR, et al. Recommendations for end-of-life care in the intensive care unit: a consensus statement by the American College of Critical Care Medicine. Crit Care Med. 2008 Mar;36(3):953-63. Resumo

284. National Consensus Project for Quality Palliative Care. Clinical practice guidelines for quality palliative care, 4th ed. 2018 [internet publication].Texto completo

285. Haun MW, Estel S, Rücker G, et al. Early palliative care for adults with advanced cancer. Cochrane Database Syst Rev. 2017 Jun 12;6:CD011129.Texto completo  Resumo

286. Ferrell BR, Temel JS, Temin S, et al. Integration of palliative care into standard oncology care: American Society of Clinical Oncology clinical practice guideline update. J Clin Oncol. 2017 Jan;35(1):96-112.Texto completo  Resumo

287. Osman H, Shrestha S, Temin S, et al. Palliative care in the global setting: ASCO resource-stratified practice guideline. J Glob Oncol. 2018 Jul;4:1-24.Texto completo  Resumo

288. Paice JA, Bohlke K, Barton D, et al. Use of opioids for adults with pain from cancer or cancer treatment: ASCO guideline. J Clin Oncol. 2023 Feb 1;41(4):914-30.Texto completo  Resumo

289. Andersen BL, Lacchetti C, Ashing K, et al. Management of anxiety and depression in adult survivors of cancer: ASCO guideline update. J Clin Oncol. 2023 Jun 20;41(18):3426-53.Texto completo  Resumo

290. National Association of Neonatal Nurses. Palliative and end-of-life care for newborns and infants: position statement #3063. February 2015 [internet publication].Texto completo

291. Linebarger JS, Johnson V, Boss RD, et al. Guidance for pediatric end-of-life care. Pediatrics. 2022 May 1;149(5):e2022057011.Texto completo  Resumo

292. Blume ED, Kirsch R, Cousino MK, et al. Palliative care across the life span for children with heart disease: a scientific statement from the American Heart Association. Circ Cardiovasc Qual Outcomes. 2023 Feb;16(2):e000114.Texto completo  Resumo

293. Bosslet GT, Pope TM, Rubenfeld GD, et al; American Thoracic Society/ American Association for Critical Care Nurses/ American College of Chest Physicians/ European Society for Intensive Care Medicine/ Society of Critical Care Medicine. An official ATS/AACN/ACCP/ESICM/SCCM policy statement: responding to requests for potentially inappropriate treatments in intensive care units. Am J Respir Crit Care Med. 2015 Jun 1;191(11):1318-30. Resumo

294. Surbone A, Baider L, Weitzman TS, et al. Psychosocial care for patients and their families is integral to supportive care in cancer: MASCC position statement. Support Care Cancer. 2010 Feb;18(2):255-63. Resumo

295. Ford DW, Koch KA, Ray DE, et al. Palliative and end-of-life care in lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest. 2013 May;143(5 Suppl):e498S-e512S.Texto completo  Resumo

296. Australian Cancer Network Melanoma Guidelines Revision Working Party. Clinical practice guidelines for the management of melanoma in Australia and New Zealand. October 2008 [internet publication].Texto completo

297. Davidson PM, Macdonald PS, Newton PJ, et al. End stage heart failure patients: palliative care in general practice. Aust Fam Physician. 2010 Dec;39(12):916-20.Texto completo  Resumo

298. Holloway RG, Arnold RM, Creutzfeldt CJ, et al. Palliative and end-of-life care in stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2014 Jun;45(6):1887-916.Texto completo  Resumo

299. Chan RJ, Webster J, Bowers A. End-of-life care pathways for improving outcomes in caring for the dying. Cochrane Database Syst Rev. 2016 Feb 12;2(2):CD008006.Texto completo  Resumo

O uso deste conteúdo está sujeito ao nosso aviso legal