Parto prematuro

Alfirevic Z, Stampalija T, Medley N. Cervical stitch (cerclage) for preventing preterm birth in singleton pregnancy. Cochrane Database Syst Rev. 2017 Jun 6;6(6):CD008991.Texto completo  Resumo

Honest H, Bachmann LM, Gupta JK, et al. Accuracy of cervicovaginal fetal fibronectin test in predicting risk of spontaneous preterm birth: systematic review. BMJ. 2002 Aug 10;325(7359):301.Texto completo  Resumo

Berghella V, Saccone G. Fetal fibronectin testing for reducing the risk of preterm birth. Cochrane Database Syst Rev. 2019 Jul 29;7(7):CD006843.Texto completo  Resumo

Crowther CA, Brown J, McKinlay CJ, et al. Magnesium sulphate for preventing preterm birth in threatened preterm labour. Cochrane Database Syst Rev. 2014 Aug 15;(8):CD001060.Texto completo  Resumo

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6. Smaill FM, Vazquez JC. Antibiotics for asymptomatic bacteriuria in pregnancy. Cochrane Database Syst Rev. 2019 Nov 25;2019(11):.Texto completo  Resumo

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14. Mohsin M, Jalaludin B. Influence of previous pregnancy outcomes and continued smoking on subsequent pregnancy outcomes: an exploratory study in Australia. BJOG. 2008 Oct;115(11):1428-35. Resumo

15. Yost NP, Bloom SL, McIntire DD, et al. A prospective observational study of domestic violence during pregnancy. Obstet Gynecol. 2005 Jul;106(1):61-5. Resumo

16. Albrechtsen S, Rasmussen S, Thoresen S, et al. Pregnancy outcome in women before and after cervical conisation: population based cohort study. BMJ. 2008 Sep 18;337:a1343.Texto completo  Resumo

17. Shennan AH, Bewley S. Why should preterm births be rising? BMJ. 2006 Apr 22;332(7547):924-5. Resumo

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19. DeFranco EA, Lewis DF, Odibo AO. Improving the screening accuracy for preterm labor: is the combination of fetal fibronectin and cervical length in symptomatic patients a useful predictor of preterm birth? A systematic review. Am J Obstet Gynecol. 2013 Mar;208(3):233.e1-6. Resumo

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22. Fogacci MF, Vettore MV, Leão AT. The effect of periodontal therapy on preterm low birth weight: a meta-analysis. Obstet Gynecol. 2011 Jan;117(1):153-65. Resumo

23. National Institute for Health and Care Excellence. Twin and triplet pregnancy. 4 September 2019 [internet publication].Texto completo

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25. Peaceman AM, Andrews WW, Thorp JM, et al. Fetal fibronectin as a predictor of preterm birth in patients with symptoms: a multicenter trial. Am J Obstet Gynecol. 1997;177:13-18. Resumo

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27. Dodd JM, Jones L, Flenady V, et al. Prenatal administration of progesterone for preventing preterm birth in women considered to be at risk of preterm birth. Cochrane Database Syst Rev. 2013;(7):CD004947.Texto completo  Resumo

28. Ananth CV, Getahun D, Peltier MR, et al. Recurrence of spontaneous versus medically indicated preterm birth. Am J Obstet Gynecol. 2006 Sep;195(3):643-50. Resumo

29. Arbyn M, Kyrgiou M, Simoens C, et al. Perinatal mortality and other severe adverse pregnancy outcomes associated with treatment of cervical intraepithelial neoplasia: meta-analysis. BMJ. 2008 Sep 18;337:a1284.Texto completo  Resumo

30. Castanon A, Brocklehurst P, Evans H, et al; PaCT Study Group. Risk of preterm birth after treatment for cervical intraepithelial neoplasia among women attending colposcopy in England: retrospective-prospective cohort study. BMJ. 2012 Aug 16;345:e5174.Texto completo  Resumo

31. Smaill FM, Vazquez JC. Antibiotics for asymptomatic bacteriuria in pregnancy. Cochrane Database Syst Rev. 2019 Nov 25;2019(11):CD000490.Texto completo  Resumo

32. Shennan A, Crawshaw S, Briley A, et al. A randomised controlled trial of metronidazole for the prevention of preterm birth in women positive for cervicovaginal fetal fibronectin: the PREMET Study. BJOG. 2006 Jan;113(1):65-74.Texto completo  Resumo

33. Shennan A, Jones G, Hawken J, et al. Fetal fibronectin test predicts delivery before 30 weeks of gestation in high risk women, but increases anxiety. BJOG. 2005 Mar;112(3):293-8.Texto completo  Resumo

34. Cnattingius S. The epidemiology of smoking during pregnancy: smoking prevalence, maternal characteristics, and pregnancy outcomes. Nicotine Tob Res. 2004 Apr;6 (suppl 2):S125-40.Texto completo  Resumo

35. Department of Health. Local data on pregnant women smoking at time of delivery. February 2010 [internet publication].Texto completo

36. Hendler I, Goldenberg RL, Mercer BM, et al. The Preterm Prediction Study: association between maternal body mass index and spontaneous and indicated preterm birth. Am J Obstet Gynecol. 2005 Mar;192(3):882-6. Resumo

37. Hincz P, Wilczynski J, Kozarzewski M, et al. Two-step test: the combined use of fetal fibronectin and sonographic examination of the uterine cervix for prediction of preterm delivery in symptomatic patients. Acta Obstet Gynecol Scand. 2002 Jan;81(1):58-63. Resumo

38. Levine LD, Sammel MD, Hirshberg A, et al. Does stage of labor at time of cesarean delivery affect risk of subsequent preterm birth? Am J Obstet Gynecol. 2015 Mar;212(3):360.e1-7.Texto completo  Resumo

39. Watson HA, Carter J, David AL, et al. Full dilation cesarean section: a risk factor for recurrent second-trimester loss and preterm birth. Acta Obstet Gynecol Scand. 2017 Sep;96(9):1100-5.Texto completo  Resumo

40. Cong A, de Vries B, Ludlow J. Does previous caesarean section at full dilatation increase the likelihood of subsequent spontaneous preterm birth? Aust N Z J Obstet Gynaecol. 2018 Jun;58(3):267-73. Resumo

41. Althuisius SM, Dekker GA, Hummel P, et al. Final results of the Cervical Incompetence Prevention Randomized Cerclage Trial (CIPRACT): therapeutic cerclage with bed rest versus bed rest alone. Am J Obstet Gynecol. 2001 Nov;185(5):1106-12. Resumo

42. Alfirevic Z, Stampalija T, Medley N. Cervical stitch (cerclage) for preventing preterm birth in singleton pregnancy. Cochrane Database Syst Rev. 2017 Jun 6;6(6):CD008991.Texto completo  Resumo

43. Berghella V, Rafael TJ, Szychowski JM, et al. Cerclage for short cervix on ultrasonography in women with singleton gestations and previous preterm birth: a meta-analysis. Obstet Gynecol. 2011 Mar;117(3):663-71. Resumo

44. National Institute for Health and Care Excellence. Preterm labour and birth. 2 August 2019 [internet publication].Texto completo

45. Berghella V, Keeler SM, To MS, et al. Effectiveness of cerclage according to severity of cervical length shortening: a meta-analysis. Ultrasound Obstet Gynecol. 2010 Apr;35(4):468-73.Texto completo  Resumo

46. Blikman MJ, Le TM, Bruinse HW, et al. Ultrasound-predicated versus history-predicated cerclage in women at risk of cervical insufficiency: a systematic review. Obstet Gynecol Surv. 2008 Dec;63(12):803-12. Resumo

47. Simcox R, Seed PT, Bennett P, et al. A randomized controlled trial of cervical scanning vs history to determine cerclage in women at high risk of preterm birth (CIRCLE trial). Am J Obstet Gynecol. 2009 Jun;200(6):623.e1-6. Resumo

48. To MS, Alfirevic Z, Heath VC, et al. Cervical cerclage for prevention of preterm delivery in women with short cervix: randomised controlled trial. Lancet. 2004 Jun 5;363(9424):1849-53. Resumo

49. Berghella V, Daly SF, Tolosa JE, et al. Prediction of preterm delivery with transvaginal ultrasonography of the cervix in patients with high-risk pregnancies: does cerclage prevent prematurity? Am J Obstet Gynecol. 1999 Oct;181(4):809-15. Resumo

50. Burger NB, Brölmann HA, Einarsson JI, et al. Effectiveness of abdominal cerclage placed via laparotomy or laparoscopy: systematic review. J Minim Invasive Gynecol. 2011 Nov-Dec;18(6):696-704. Resumo

51. Simcox R, Shennan A. Cervical cerclage in the prevention of preterm birth. Best Pract Res Clin Obstet Gynaecol. 2007 Oct;21(5):831-42. Resumo

52. Lesser KB, Childers JM, Surwit EA. Transabdominal cerclage: a laparoscopic approach. Obstet Gynecol. 1998 May;91(5 Pt 2):855-6. Resumo

53. Novy MJ. Transabdominal cervicoisthmic cerclage: a reappraisal 25 years after its introduction. Am J Obstet Gynecol. 1991 Jun;164(6 Pt 1):1635-41; discussion 1641-2. Resumo

54. Shennan A, Chandiramani M, Bennett P, et al. MAVRIC: a multicenter randomized controlled trial of transabdominal vs transvaginal cervical cerclage. Am J Obstet Gynecol. 2020 Mar;222(3):261.e1-261.e9. Resumo

55. Ehsanipoor RM, Seligman NS, Saccone G, et al. Physical examination-indicated cerclage: a systematic review and meta-analysis. Obstet Gynecol. 2015 Jul;126(1):125-35. Resumo

56. Olatunbosun OA, al-Nuaim L, Turnell RW. Emergency cerclage compared with bed rest for advanced cervical dilatation in pregnancy. Int Surg. 1995 Apr-Jun;80(2):170-4. Resumo

57. Conde-Agudelo A, Romero R, Nicolaides K, et al. Vaginal progesterone vs. cervical cerclage for the prevention of preterm birth in women with a sonographic short cervix, previous preterm birth, and singleton gestation: a systematic review and indirect comparison metaanalysis. Am J Obstet Gynecol. 2013 Jan;208(1):42.e1-42.e18.Texto completo  Resumo

58. Heath VC, Southall TR, Souka AP, et al. Cervical length at 23 weeks of gestation: prediction of spontaneous preterm delivery. Ultrasound Obstet Gynecol. 1998 Nov;12(5):312-7. Resumo

59. Nygren P, Fu R, Freeman M, et al. Evidence on the benefits and harms of screening and treating pregnant women who are asymptomatic for bacterial vaginosis: an update review for the U.S. Preventive Services Task Force. Ann Intern Med. 2008 Feb 5;148(3):220-33.Texto completo  Resumo

60. Shennan AH, Chandiramani M. Antibiotics for spontaneous preterm birth. BMJ. 2008 Dec 30;337:a3015. Resumo

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62. Michalowicz BS, Hodges JS, DiAngelis AJ, et al. OPT Study. Treatment of periodontal disease and the risk of preterm birth. N Engl J Med. 2006 Nov 2;355(18):1885-94.Texto completo  Resumo

63. Sanchez-Ramos L, Delke I, Zamora J, et al. Fetal fibronectin as a short-term predictor of preterm birth in symptomatic patients: a meta-analysis. Obstet Gynecol. 2009 Sep;114(3):631-40. Resumo

64. Kuhrt K, Smout E, Hezelgrave N, et al. Development and validation of a predictive tool for spontaneous preterm birth incorporating cervical length and quantitative fetal fibronectin in asymptomatic high-risk women. Ultrasound Obstet Gynecol. 2016 Jan;47(1):104-9. Resumo

65. Kuhrt K, Hezelgrave N, Foster C, et al. Development and validation of a tool incorporating quantitative fetal fibronectin to predict spontaneous preterm birth in symptomatic women. Ultrasound Obstet Gynecol. 2016 Feb;47(2):210-6. Resumo

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67. Boots AB, Sanchez-Ramos L, Bowers DM, et al. The short-term prediction of preterm birth: a systematic review and diagnostic metaanalysis. Am J Obstet Gynecol. 2014 Jan;210(1):54.e1-54.e10.Texto completo  Resumo

68. Royal College of Obstetricians and Gynaecologists. Care of women presenting with suspected preterm prelabour rupture of membranes from 24+0 weeks of gestation. Green-top Guideline No. 73. June 2019 [internet publication].Texto completo

69. Berghella V, Saccone G. Cervical assessment by ultrasound for preventing preterm delivery. Cochrane Database Syst Rev. 2019 Sep 25;9(9):CD007235.Texto completo  Resumo

70. Honest H, Bachmann LM, Gupta JK, et al. Accuracy of cervicovaginal fetal fibronectin test in predicting risk of spontaneous preterm birth: systematic review. BMJ. 2002 Aug 10;325(7359):301.Texto completo  Resumo

71. Brownfoot FC, Gagliardi DI, Bain E, et al. Different corticosteroids and regimens for accelerating fetal lung maturation for women at risk of preterm birth. Cochrane Database Syst Rev. 2013 Aug 29;(8):CD006764.Texto completo  Resumo

72. Berghella V, Saccone G. Fetal fibronectin testing for reducing the risk of preterm birth. Cochrane Database Syst Rev. 2019 Jul 29;7(7):CD006843.Texto completo  Resumo

73. Bruijn MM, Kamphuis EI, Hoesli IM, et al. The predictive value of quantitative fibronectin testing in combination with cervical length measurement in symptomatic women. Am J Obstet Gynecol. 2016 Dec;215(6):793.e1-793.e8. Resumo

74. Bruijn M, Vis JY, Wilms FF, et al. Quantitative fetal fibronectin testing in combination with cervical length measurement in the prediction of spontaneous preterm delivery in symptomatic women. BJOG. 2016 Nov;123(12):1965-71.Texto completo  Resumo

75. Abbott DS, Radford SK, Seed PT, et al. Evaluation of a quantitative fetal fibronectin test for spontaneous preterm birth in symptomatic women. Am J Obstet Gynecol. 2013 Feb;208(2):122.e1-6.Texto completo  Resumo

76. Deshpande SN, van Asselt AD, Tomini F, et al. Rapid fetal fibronectin testing to predict preterm birth in women with symptoms of premature labour: a systematic review and cost analysis. Health Technol Assess. 2013 Sep;17(40):1-138.Texto completo  Resumo

77. Abbott DS, Hezelgrave NL, Seed PT, et al. Quantitative fetal fibronectin to predict preterm birth in asymptomatic women at high risk. Obstet Gynecol. 2015 May;125(5):1168-76. Resumo

78. Esplin MS, Elovitz MA, Iams JD, et al. Predictive accuracy of serial transvaginal cervical lengths and quantitative vaginal fetal fibronectin levels for spontaneous preterm birth among nulliparous women. JAMA. 2017 Mar 14;317(10):1047-1056. Resumo

79. Yoon BH, Park CW, Chaiworapongsa T. Intrauterine infection and the development of cerebral palsy. BJOG. 2003 Apr;110(suppl 20):124-7.Texto completo  Resumo

80. Kenyon S, Pike K, Jones DR, et al. Childhood outcomes after prescription of antibiotics to pregnant women with spontaneous preterm labor: 7-year follow-up of the ORACLE II trial. Lancet. 2008 Oct 11;372(9646):1319-27. Resumo

81. Abenhaim HA, Morin L, Benjamin A. Does availability of fetal fibronectin testing in the management of threatened preterm labor affect the utilization of hospital resources? J Obstet Gynaecol Can. 2005 Jul;27(7):689-94. Resumo

82. Watts DH, Krohn MA, Hillier SL, et al. Characteristics of women in preterm labor associated with elevated C-reactive protein levels. Obstet Gynecol. 1993 Oct;82(4 Pt 1):509-14. Resumo

83. Lewis DF, Adair CD, Weeks JW, et al. A randomized clinical trial of daily nonstress testing versus biophysical profile in the management of preterm premature rupture of membranes. Am J Obstet Gynecol. 1999 Dec;181(6):1495-9. Resumo

84. Kenyon S, Boulvain M, Neilson JP. Antibiotics for preterm rupture of membranes. Cochrane Database Syst Rev. 2013 Dec 2;(12):CD001058.Texto completo  Resumo

85. Combs CA, McCune M, Clark R, et al. Aggressive tocolysis does not prolong pregnancy or reduce neonatal morbidity after preterm premature rupture of the membranes. Am J Obstet Gynecol. 2004 Jun;190(6):1723-8; discussion 1728-31. Resumo

86. Morris JM, Roberts CL, Bowen JR, et al. Immediate delivery compared with expectant management after preterm pre-labour rupture of the membranes close to term (PPROMT trial): a randomised controlled trial. Lancet. 2016 Jan 30;387(10017):444-52. Resumo

87. Bond DM, Middleton P, Levett KM, et al. Planned early birth versus expectant management for women with preterm prelabour rupture of membranes prior to 37 weeks' gestation for improving pregnancy outcome. Cochrane Database Syst Rev. 2017 Mar 3;3(3):CD004735.Texto completo  Resumo

88. The American College of Obstetricians and Gynecologists. ACOG Committee Opinion No. 764: Medically indicated late-preterm and early-term deliveries. Obstet Gynecol. 2019 Feb;133(2):e151-55.Texto completo  Resumo

89. The American Collage of Obstetricians and Gynecologists. ACOG Committee Opinion No. 765: Avoidance of nonmedically indicated early-term deliveries and associated neonatal morbidities. Obstet Gynecol. 2019 Feb;133(2):e156-63.Texto completo  Resumo

90. Roberts D, Brown J, Medley N, et al. Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth. Cochrane Database Syst Rev. 2017 Mar 21;3(3):CD004454.Texto completo  Resumo

91. Committee on Obstetric Practice. Committee Opinion No. 713: Antenatal corticosteroid therapy for fetal maturation. Obstet Gynecol. 2017 Aug;130(2):e102-9. Resumo

92. Elimian A, Garry D, Figueroa R, et al. Antenatal betamethasone compared with dexamethasone (betacode trial): a randomized controlled trial. Obstet Gynecol. 2007 Jul;110(1):26-30. Resumo

93. Gyamfi-Bannerman C, Thom EA, Blackwell SC, et al. Antenatal betamethasone for women at risk for late preterm delivery. N Engl J Med. 2016 Apr 7;374(14):1311-20. Resumo

94. Saccone G, Berghella V. Antenatal corticosteroids for maturity of term or near term fetuses: systematic review and meta-analysis of randomized controlled trials. BMJ. 2016 Oct 12;355:i5044.Texto completo  Resumo

95. Murphy KE, Hannah ME, Willan AR, et al. Multiple courses of antenatal corticosteroids for preterm birth (MACS): a randomised controlled trial. MACS Collaborative Group. Lancet. 2008 Dec 20;372(9656):2143-51. Resumo

96. Crowther CA, Haslam RR, Hiller JE, et al; Australasian Collaborative Trial of Repeat Doses of Steroids (ACTORDS) Study Group. Neonatal respiratory distress syndrome after repeat exposure to antenatal corticosteroids: a randomised controlled trial. Lancet. 2006 Jun 10;367(9526):1913-9. Resumo

97. Crowther CA, McKinlay CJ, Middleton P, et al. Repeat doses of prenatal corticosteroids for women at risk of preterm birth for preventing neonatal respiratory disease. Cochrane Database Syst Rev. 2015 Jul 5;2015(7):CD003935.Texto completo  Resumo

98. McKinlay CJ, Crowther CA, Middleton P, et al. Repeat antenatal glucocorticoids for women at risk of preterm birth: a Cochrane Systematic Review. Am J Obstet Gynecol. 2012 Mar;206(3):187-94.Texto completo  Resumo

99. Althabe F, Belizán JM, McClure EM, et al. A population-based, multifaceted strategy to implement antenatal corticosteroid treatment versus standard care for the reduction of neonatal mortality due to preterm birth in low-income and middle-income countries: the ACT cluster-randomised trial. Lancet. 2015 Feb 14;385(9968):629-39. Resumo

100. Neilson JP, West HM, Dowswell T. Betamimetics for inhibiting preterm labour. Cochrane Database Syst Rev. 2014 Feb 5;(2):CD004352.Texto completo  Resumo

101. Flenady V, Wojcieszek AM, Papatsonis DN, et al. Calcium channel blockers for inhibiting preterm labour. Cochrane Database Syst Rev. 2014 Jun 5;2014;(6):CD002255.Texto completo  Resumo

102. Flenady V, Reinebrant HE, Liley HG, et al. Oxytocin receptor antagonists for inhibiting preterm labour. Cochrane Database Syst Rev. 2014 Jun 6;(6):CD004452.Texto completo  Resumo

103. van Vliet EO, Nijman TA, Schuit E, et al. Nifedipine versus atosiban for threatened preterm birth (APOSTEL III): a multicentre, randomised controlled trial. Lancet. 2016 May 21;387(10033):2117-24. Resumo

104. Khan K, Zamora J, Lamont RF, et al. Safety concerns for the use of calcium channel blockers in pregnancy for the treatment of spontaneous preterm labour and hypertension: a systematic review and meta-regression analysis. J Matern Fetal Neonatal Med. 2010 Sep;23(9):1030-8. Resumo

105. Papatsonis D, Flenady V, Liley H. Maintenance therapy with oxytocin antagonists for inhibiting preterm birth after threatened preterm labour. Cochrane Database Syst Rev. 2013 Oct 13;(10):CD005938.Texto completo  Resumo

106. Royal College of Obstetricians and Gynaecologists. Group B streptococcal disease, early-onset. Green-top Guideline No. 36. September 2017 [internet publication].Texto completo

107. Goya M, Pratcorona L, Merced C, et al; Pesario Cervical para Evitar Prematuridad (PECEP) Trial Group. Cervical pessary in pregnant women with a short cervix (PECEP): an open-label randomised controlled trial. Lancet. 2012 May 12;379(9828):1800-6. Resumo

108. Liem S, Schuit E, Hegeman M, et al. Cervical pessaries for prevention of preterm birth in women with a multiple pregnancy (ProTWIN): a multicentre, open-label randomised controlled trial. Lancet. 2013 Oct 19;382(9901):1341-9. Resumo

109. Nicolaides KH, Syngelaki A, Poon LC, et al. A randomized trial of a cervical pessary to prevent preterm singleton birth. N Engl J Med. 2016 Mar 17;374(11):1044-52.Texto completo  Resumo

110. Nicolaides KH, Syngelaki A, Poon LC, et al. Cervical pessary placement for prevention of preterm birth in unselected twin pregnancies: a randomized controlled trial. Am J Obstet Gynecol. 2016 Jan;214(1):3.e1-9. Resumo

111. Saccone G, Maruotti GM, Giudicepietro A, et al. Effect of cervical pessary on spontaneous preterm birth in women with singleton pregnancies and short cervical length: a randomized clinical trial. JAMA. 2017 Dec 19;318(23):2317-24.Texto completo  Resumo

112. Australian Research Centre for Health of Women and Babies, UoA. Antenatal magnesium sulphate prior to preterm birth for neuroprotection of the fetus, infant and child. March 2010 [internet publication].

113. US Food and Drug Administration. Magnesium sulfate: drug safety communication - recommendation against prolonged use in pre-term labor. May 2013 [internet publication].Texto completo

114. Medicines and Healthcare products Regulatory Agency. Magnesium sulfate: risk of skeletal adverse effects in the neonate following prolonged or repeated use in pregnancy. 17 May 2019 [internet publication].Texto completo

115. Crowther CA, Brown J, McKinlay CJ, et al. Magnesium sulphate for preventing preterm birth in threatened preterm labour. Cochrane Database Syst Rev. 2014 Aug 15;(8):CD001060.Texto completo  Resumo

116. da Fonseca EB, Bittar RE, Carvalho MH, et al. Prophylactic administration of progesterone by vaginal suppository to reduce the incidence of spontaneous preterm birth in women at increased risk: a randomized placebo-controlled double-blind study. Am J Obstet Gynecol. 2003 Feb;188(2):419-24. Resumo

117. O'Brien JM, Adair CD, Lewis DF, et al. Progesterone vaginal gel for the reduction of recurrent preterm birth: primary results from a randomized, double-blind, placebo-controlled trial. Ultrasound Obstet Gynecol. 2007 Oct;30(5):687-96. Resumo

118. DeFranco EA, O'Brien JM, Adair CD, et al. Vaginal progesterone is associated with a decrease in risk for early preterm birth and improved neonatal outcome in women with a short cervix: a secondary analysis from a randomized, double-blind, placebo-controlled trial. Ultrasound Obstet Gynecol. 2007 Oct;30(5):697-705.Texto completo  Resumo

119. Fonseca EB, Celik E, Parra M, et al. Progesterone and the risk of preterm birth among women with a short cervix. N Engl J Med. 2007 Aug 2;357(5):462-9.Texto completo  Resumo

120. Romero R, Nicolaides K, Conde-Agudelo A, et al. Vaginal progesterone in women with an asymptomatic sonographic short cervix in the midtrimester decreases preterm delivery and neonatal morbidity: a systematic review and metaanalysis of individual patient data. Am J Obstet Gynecol. 2012 Feb;206(2):124.e1-19.Texto completo  Resumo

121. Norman JE, Marlow N, Messow CM, et al. Vaginal progesterone prophylaxis for preterm birth (the OPPTIMUM study): a multicentre, randomised, double-blind trial. Lancet. 2016 May 21;387(10033):2106-16.Texto completo  Resumo

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