კოლორექტული სიმსივნე

წყაროები

ძირითადი სტატიები

National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: colorectal cancer screening [internet publication].სრული ტექსტი

National Institute for Health and Care Excellence. Colorectal cancer. Dec 2021 [internet publication].სრული ტექსტი

National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: rectal cancer [internet publication].სრული ტექსტი

National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: colon cancer [internet publication].სრული ტექსტი

Sepulveda AR, Hamilton SR, Allegra CJ, et al. Molecular biomarkers for the evaluation of colorectal cancer: guideline from the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and American Society of Clinical Oncology. Arch Pathol Lab Med. 2017 Feb 6;141(5):625-57.სრული ტექსტი  აბსტრაქტი

გამოყენებული სტატიები

1. Ansa BE, Coughlin SS, Alema-Mensah E, et al. Evaluation of Colorectal Cancer Incidence Trends in the United States (2000-2014). J Clin Med. 2018 Jan 30;7(2):.სრული ტექსტი  აბსტრაქტი

2. American College of Surgeons. AJCC version 9 cancer staging system. 2024 [internet publication].სრული ტექსტი

3. Thorne K, Hutchings HA, Elwyn G. The effects of the two-week rule on NHS colorectal cancer diagnostic services: a systematic literature review. BMC Health Serv Res. 2006 Apr 3;6:43-7.სრული ტექსტი  აბსტრაქტი

4. National Cancer Institute: Surveillance, Epidemiology, and End Results Program. Cancer stat facts: colorectal cancer. 2023 [internet publication].სრული ტექსტი

5. American Cancer Society. Cancer facts and figures 2024. 2024 [internet publication].სრული ტექსტი

6. GBD 2019 Colorectal Cancer Collaborators. Global, regional, and national burden of colorectal cancer and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Gastroenterol Hepatol. 2022 Jul;7(7):627-47.სრული ტექსტი  აბსტრაქტი

7. Cancer Research UK. Bowel cancer deaths drop by a third in 20 years. Aug 2017 [internet publication].სრული ტექსტი

8. Fedewa SA, Flanders WD, Ward KC, et al. Racial and ethnic disparities in interval colorectal cancer incidence: a population-based cohort study. Ann Intern Med. 2017 Jun 20;166(12):857-66. აბსტრაქტი

9. American Cancer Society. Colorectal cancer facts and figures, 2020-2022. 2020 [internet publication].სრული ტექსტი

10. Butterworth AS, Higgins JP, Pharoah P. Relative and absolute risk of colorectal cancer for individuals with a family history: a meta-analysis. Eur J Cancer. 2006 Jan;42(2):216-27. აბსტრაქტი

11. Song M, Emilsson L, Roelstraete B, et al. Risk of colorectal cancer in first degree relatives of patients with colorectal polyps: nationwide case-control study in Sweden. BMJ. 2021 May 4;373:n877.სრული ტექსტი  აბსტრაქტი

12. Jasperson KW, Tuohy TM, Neklason DW, et al. Hereditary and familial colon cancer. Gastroenterology. 2010 Jun;138(6):2044-58.სრული ტექსტი  აბსტრაქტი

13. Ma H, Brosens LA, Offerhaus GJ, et al. Pathology and genetics of hereditary colorectal cancer. Pathology. 2017 Nov 21;50(1):49-59. აბსტრაქტი

14. Dong Y, Zhou J, Zhu Y, et al. Abdominal obesity and colorectal cancer risk: systematic review and meta-analysis of prospective studies. Biosci Rep. 2017 Dec 12;37(6):BSR20170945.სრული ტექსტი  აბსტრაქტი

15. Wong MC, Chan CH, Cheung W, et al. Association between investigator-measured body-mass index and colorectal adenoma: a systematic review and meta-analysis of 168,201 subjects. Eur J Epidemiol. 2017 Dec 29;33(1):15-26.სრული ტექსტი  აბსტრაქტი

16. Doleman B, Mills KT, Lim S, et al. Body mass index and colorectal cancer prognosis: a systematic review and meta-analysis. Tech Coloproctol. 2016 Jun 24;20(8):517-35. აბსტრაქტი

17. Ma Y, Yang Y, Wang F, et al. Obesity and risk of colorectal cancer: a systematic review of prospective studies. PLoS One. 2013 Jan 17;8(1):e53916.სრული ტექსტი  აბსტრაქტი

18. Hidayat K, Yang CM, Shi BM. Body fatness at an early age and risk of colorectal cancer. Int J Cancer. 2018 Feb 15;142(4):729-40.სრული ტექსტი  აბსტრაქტი

19. Liu PH, Wu K, Ng K, et al. Association of obesity with risk of early-onset colorectal cancer among women. JAMA Oncol. 2019 Jan 1;5(1):37-44.სრული ტექსტი  აბსტრაქტი

20. Mao Y, Pan S, Wen SW, et al; Canadian Cancer Registries Epidemiology Research Group. Physical inactivity, energy intake, obesity and the risk of rectal cancer in Canada. Int J Cancer. 2003 Jul 20;105(6):831-7. აბსტრაქტი

21. Wolin KY, Yan Y, Colditz GA, Lee IM. Physical activity and colon cancer prevention: a meta-analysis. Br J Cancer. 2009 Feb 24;100(4):611-6.სრული ტექსტი  აბსტრაქტი

22. Chao A, Thun MJ, Connell CJ, et al. Meat consumption and risk of colorectal cancer. JAMA. 2005 Jan 12;293(2):172-82.სრული ტექსტი  აბსტრაქტი

23. Norat T, Bingham S, Ferrari P, et al. Meat, fish, and colorectal cancer risk: the European Prospective Investigation into cancer and nutrition. J Natl Cancer Inst. 2005 Jun 15;97(12):906-16.სრული ტექსტი  აბსტრაქტი

24. Willett WC, Stampfer MJ, Colditz GA, et al. Relation of meat, fat, and fiber intake to the risk of colon cancer in a prospective study among women. N Engl J Med. 1990 Dec 13;323(24):1664-72. აბსტრაქტი

25. Huang J, Pan G, Jiang H, et al. A meta-analysis between dietary carbohydrate intake and colorectal cancer risk: evidence from 17 observational studies. Biosci Rep. 2017 Apr 10;37(2):BSR20160553.სრული ტექსტი  აბსტრაქტი

26. Ferguson LR, Harris PJ. The dietary fibre debate: more food for thought. Lancet. 2003 May 3;361(9368):1487-8. აბსტრაქტი

27. Song M, Wu K, Meyerhardt JA, et al. Fiber intake and survival after colorectal cancer diagnosis. JAMA Oncol. 2018 Jan 1;4(1):71-9.სრული ტექსტი  აბსტრაქტი

28. Ma Y, Hu M, Zhou L, et al. Dietary fiber intake and risks of proximal and distal colon cancers: a meta-analysis. Medicine (Baltimore). 2018 Sep;97(36):e11678.სრული ტექსტი  აბსტრაქტი

29. National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: colorectal cancer screening [internet publication].სრული ტექსტი

30. Chao A, Thun MJ, Jacobs EJ, et al. Cigarette smoking and colorectal cancer mortality in the cancer prevention study II. J Natl Cancer Inst. 2000 Dec 6;92(23):1888-96.სრული ტექსტი  აბსტრაქტი

31. Hannan LM, Jacobs EJ, Thun MJ. The association between cigarette smoking and risk of colorectal cancer in a large prospective cohort from the United States. Cancer Epidemiol Biomarkers Prev. 2009 Dec;18(12):3362-7.სრული ტექსტი  აბსტრაქტი

32. Fedirko V, Tramacere I, Bagnardi V, et al. Alcohol drinking and colorectal cancer risk: an overall and dose-response meta-analysis of published studies. Ann Oncol. 2011 Sep;22(9):1958-72.სრული ტექსტი  აბსტრაქტი

33. Arnold CN, Goel A, Blum HE, et al. Molecular pathogenesis of colorectal cancer. Cancer. 2005 Nov 15;104(10):2035-47.სრული ტექსტი  აბსტრაქტი

34. Pino MS, Chung DC. The chromosomal instability pathway in colon cancer. Gastroenterology. 2010 Jun;138(6):2059-72.სრული ტექსტი  აბსტრაქტი

35. Sinicrope FA, Sargent DJ. Molecular pathways: microsatellite instability in colorectal cancer: prognostic, predictive, and therapeutic implications. Clin Cancer Res. 2012 Mar 15;18(6):1506-12.სრული ტექსტი  აბსტრაქტი

36. Nazemalhosseini Mojarad E, Kuppen PJ, Aghdaei HA, et al. The CpG island methylator phenotype (CIMP) in colorectal cancer. Gastroenterol Hepatol Bed Bench. 2013 Summer;6(3):120-8.სრული ტექსტი  აბსტრაქტი

37. Sundermeyer ML, Meropol NJ, Rogatko A, et al. Changing patterns of bone and brain metastases in patients with colorectal cancer. Clin Colorectal Cancer. 2005 Jul;5(2):108-13. აბსტრაქტი

38. Christensen TD, Spindler KL, Palshof JA, et al. Systematic review: brain metastases from colorectal cancer - incidence and patient characteristics. BMC Cancer. 2016 Apr 1;16:260.სრული ტექსტი  აბსტრაქტი

39. Issaka RB, Chan AT, Gupta S. AGA clinical practice update on risk stratification for colorectal cancer screening and post-polypectomy surveillance: expert review. Gastroenterology. 2023 Nov;165(5):1280-91.სრული ტექსტი  აბსტრაქტი

40. Petersen GM, Slack J, Nakamura Y. Screening guidelines and premorbid diagnosis of familial adenomatous polyposis using linkage. Gastroenterology. 1991 Jun;100(6):1658-64. აბსტრაქტი

41. Vasen HF, Blanco I, Aktan-Collan K, et al. Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts. Gut. 2013 Feb 13;62(6):812-23.სრული ტექსტი  აბსტრაქტი

42. American College of Obstetricians and Gynecologists. Practice bulletin no. 147: lynch syndrome. Nov 2014 [internet publication].სრული ტექსტი

43. Meyers M, Theodosiou M, Acharya S, et al. Cell cycle regulation of the human DNA mismatch repair genes hMSH2, hMLH1, and hPMS2. Cancer Res. 1997 Jan 15;57(2):206-8. აბსტრაქტი

44. Wang Q, Lasset C, Desseigne F, et al. Prevalence of germline mutations of hMLH1, hMSH2, hPMS1, hPMS2, and hMSH6 genes in 75 French kindreds with nonpolyposis colorectal cancer. Hum Genet. 1999 Jul-Aug;105(1-2):79-85. აბსტრაქტი

45. Fu L, Sheng JQ, Li XO, et al. Mismatch repair gene mutation analysis and colonoscopy surveillance in Chinese Lynch syndrome families. Cell Oncol (Dordr). 2013 Jun;36(3):225-31. აბსტრაქტი

46. De Jong AE, Morreau H, Van Puijenbroek M, et al. The role of mismatch repair gene defects in the development of adenomas in patients with HNPCC. Gastroenterology. 2004 Jan;126(1):42-8. აბსტრაქტი

47. Yamamoto H, Imai K. Microsatellite instability: an update. Arch Toxicol. 2015 Feb 22;89(6):899-921. აბსტრაქტი

48. Kidambi TD, Kohli DR, Samadder NJ, et al. Hereditary polyposis syndromes. Curr Treat Options Gastroenterol. 2019 Dec;17(4):650-65. აბსტრაქტი

49. Giardiello FM, Bresinger JD, Tersmette AC, et al. Very high risk of cancer in familial Peutz-Jeghers syndrome. Gastroenterology. 2000 Dec;119(6):1447-53. აბსტრაქტი

50. Bopanna S, Ananthakrishnan AN, Kedia S, et al. Risk of colorectal cancer in Asian patients with ulcerative colitis: a systematic review and meta-analysis. Lancet Gastroenterol Hepatol. 2017 Feb 21;2(4):269-76.სრული ტექსტი  აბსტრაქტი

51. Castaño-Milla C, Chaparro M, Gisbert JP. Systematic review with meta-analysis: the declining risk of colorectal cancer in ulcerative colitis. Aliment Pharmacol Ther. 2014 Apr;39(7):645-59.სრული ტექსტი  აბსტრაქტი

52. Jess T, Gamborg M, Matzen P, et al. Increased risk of intestinal cancer in Crohn's disease: a meta-analysis of population-based cohort studies. Am J Gastroenterol. 2005 Dec;100(12):2724-9. აბსტრაქტი

53. Gilat T, Fireman Z, Grossman A, et al. Colorectal cancer in patients with ulcerative colitis. A population study in central Israel. Gastroenterology. 1988 Apr;94(4):870-7. აბსტრაქტი

54. Eaden JA, Abrams KR, Mayberry JF. The risk of colorectal cancer in ulcerative colitis: a meta-analysis. Gut. 2001 Apr;48(4):526-35.სრული ტექსტი  აბსტრაქტი

55. Renehan AG, O'Dwyer ST, Shalet SM. Screening colonoscopy for acromegaly in perspective. Clin Endocrinol (Oxf). 2001 Dec;55(6):731-3. აბსტრაქტი

56. Dal J, Leisner MZ, Hermansen K, et al. Cancer incidence in patients with acromegaly: a cohort study and meta-analysis of the literature. J Clin Endocrinol Metab. 2018 Jun 1;103(6):2182-8.სრული ტექსტი  აბსტრაქტი

57. Kruk J, Aboul-Enein HY. Physical activity and cancer prevention: updating the evidence. The role of oxidative stress in carcinogenesis. Curr Cancer Ther Rev. 2007;3(2):81-95.

58. Wu W, Guo F, Ye J, et al. Pre- and post-diagnosis physical activity is associated with survival benefits of colorectal cancer patients: a systematic review and meta-analysis. Oncotarget. 2016 Aug 9;7(32):52095-103.სრული ტექსტი  აბსტრაქტი

59. Bouvard V, Loomis D, Guyton KZ, et al. Carcinogenicity of consumption of red and processed meat. Lancet Oncol. 2015 Dec;16(16):1599-600. აბსტრაქტი

60. Guirguis-Blake JM, Evans CV, Perdue LA, et al. Aspirin use to prevent cardiovascular disease and colorectal cancer: updated evidence report and systematic review for the US Preventive Services Task Force. JAMA. 2022 Apr 26;327(16):1585-97.სრული ტექსტი  აბსტრაქტი

61. Shaukat A, Kahi CJ, Burke CA, et al. ACG clinical guidelines: colorectal cancer screening 2021. Am J Gastroenterol. 2021 Mar 1;116(3):458-79.სრული ტექსტი  აბსტრაქტი

62. National Institute for Health and Care Excellence. Colorectal cancer. Dec 2021 [internet publication].სრული ტექსტი

63. Burn J, Sheth H, Elliott F, et al. Cancer prevention with aspirin in hereditary colorectal cancer (Lynch syndrome), 10-year follow-up and registry-based 20-year data in the CAPP2 study: a double-blind, randomised, placebo-controlled trial. Lancet. 2020 Jun 13;395(10240):1855-63.სრული ტექსტი  აბსტრაქტი

64. Cook NR, Lee IM, Zhang SM, et al. Alternate-day, low-dose aspirin and cancer risk: long-term observational follow-up of a randomized trial. Ann Intern Med. 2013 Jul 16;159(2):77-85.სრული ტექსტი  აბსტრაქტი

65. Emilsson L, Holme Ø, Bretthauer M, et al. Systematic review with meta-analysis: the comparative effectiveness of aspirin vs. screening for colorectal cancer prevention. Aliment Pharmacol Ther. 2017 Jan;45(2):193-204.სრული ტექსტი  აბსტრაქტი

66. Giorli G, Rouette J, Yin H, et al. Prediagnostic use of low-dose aspirin and risk of incident metastasis and all-cause mortality among patients with colorectal cancer. Br J Clin Pharmacol. 2020 Nov;86(11):2266-73.სრული ტექსტი  აბსტრაქტი

67. Guo CG, Ma W, Drew DA, et al. Aspirin use and risk of colorectal cancer among older adults. JAMA Oncol. 2021 Mar 1;7(3):428-35.სრული ტექსტი  აბსტრაქტი

68. Nishihara R, Lochhead P, Kuchiba A, et al. Aspirin use and risk of colorectal cancer according to BRAF mutation status. JAMA. 2013 Jun 26;309(24):2563-71.სრული ტექსტი  აბსტრაქტი

69. Tomić T, Domínguez-López S, Barrios-Rodríguez R. Non-aspirin non-steroidal anti-inflammatory drugs in prevention of colorectal cancer in people aged 40 or older: a systematic review and meta-analysis. Cancer Epidemiol. 2019 Feb;58:52-62. აბსტრაქტი

70. Rostom A, Dubé C, Lewin G, et al. Nonsteroidal anti-inflammatory drugs and cyclooxygenase-2 inhibitors for primary prevention of colorectal cancer: a systematic review prepared for the U.S. Preventive Services Task Force. Ann Intern Med. 2007 Mar 6;146(5):376-89.სრული ტექსტი  აბსტრაქტი

71. Baron JA, Beach M, Mandel JS, et al, for The Calcium Polyp Prevention Study Group. Calcium supplements for the prevention of colorectal adenomas. N Engl J Med. 1999 Jan 14;340(2):101-7.სრული ტექსტი  აბსტრაქტი

72. Ben S, Du M, Ma G, et al. Vitamin B2 intake reduces the risk for colorectal cancer: a dose-response analysis. Eur J Nutr. 2019 Jun;58(4):1591-602. აბსტრაქტი

73. Aglago EK, Huybrechts I, Murphy N, et al. Consumption of fish and long-chain n-3 polyunsaturated fatty acids is associated with reduced risk of colorectal cancer in a large European cohort. Clin Gastroenterol Hepatol. 2020 Mar;18(3):654-66.e6.სრული ტექსტი  აბსტრაქტი

74. Zauber AG, Winawer SJ, O'Brien MJ, et al. Colonoscopic polypectomy and long-term prevention of colorectal-cancer deaths. N Engl J Med. 2012 Feb 23;366(8):687-96.სრული ტექსტი  აბსტრაქტი

75. Rex DK, Boland CR, Dominitz JA, et al. Colorectal cancer screening: recommendations for physicians and patients from the U.S. Multi-Society Task Force on Colorectal Cancer. Am J Gastroenterol. 2017 Jun 6;112(7):1016-30.სრული ტექსტი  აბსტრაქტი

76. National Institute for Health and Care Excellence. Suspected cancer: recognition and referral. Aug 2023 [internet publication].სრული ტექსტი

77. Rockey DC, Cello JP. Evaluation of the gastrointestinal tract in patients with iron-deficiency anemia. N Engl J Med. 1993 Dec 2;329(23):1691-5.სრული ტექსტი  აბსტრაქტი

78. Raje D, Mukhtar H, Oshowo A, et al. What proportion of patients referred to secondary care with iron deficiency anemia have colon cancer? Dis Colon Rectum. 2007 Aug;50(8):1211-4. აბსტრაქტი

79. Atkin W, Dadswell E, Wooldrage K, et al; SIGGAR Investigators. Computed tomographic colonography versus colonoscopy for investigation of patients with symptoms suggestive of colorectal cancer (SIGGAR): a multicentre randomised trial. Lancet. 2013 Apr 6;381(9873):1194-202. აბსტრაქტი

80. Vogel JD, Felder SI, Bhama AR, et al. The American Society of Colon and Rectal Surgeons clinical practice guidelines for the management of colon cancer. Dis Colon Rectum. 2022 Feb 1;65(2):148-77.სრული ტექსტი  აბსტრაქტი

81. Bressler B, Paszat LF, Chen Z, et al. Rates of new or missed colorectal cancers after colonoscopy and their risk factors: a population-based analysis. Gastroenterology. 2007 Jan;132(1):96-102. აბსტრაქტი

82. Lieberman DA, Weiss DG, Bond JH, et al; Veterans Affairs Cooperative Study Group 380. Use of colonoscopy to screen asymptomatic adults for colorectal cancer. N Engl J Med. 2000 Jul 20;343(3):162-8.სრული ტექსტი  აბსტრაქტი

83. Luning T, Keemers-Gels M, Barendregt W, et al. Colonoscopic perforations: a review of 30,366 patients. Surg Endosc. 2007 Jun;21(6):994-7. აბსტრაქტი

84. Holme Ø, Bretthauer M, Fretheim A, et al. Flexible sigmoidoscopy versus faecal occult blood testing for colorectal cancer screening in asymptomatic individuals. Cochrane Database Syst Rev. 2013 Oct 1;(9):CD009259.სრული ტექსტი  აბსტრაქტი

85. Gluecker TM, Johnson CD, Harmsen WS, et al. Colorectal cancer screening with CT colonography, colonoscopy, and double-contrast barium enema examination: prospective assessment of patient perceptions and preferences. Radiology. 2003 May;227(2):378-84. აბსტრაქტი

86. Bosworth HB, Rockey DC, Paulson EK, et al. Prospective comparison of patient experience with colon imaging tests. Am J Med. 2006 Sep;119(9):791-9. აბსტრაქტი

87. Halligan S, Wooldrage K, Dadswell E, et al; SIGGAR investigators. Computed tomographic colonography versus barium enema for diagnosis of colorectal cancer or large polyps in symptomatic patients (SIGGAR): a multicentre randomised trial. Lancet. 2013 Apr 6;381(9873):1185-93. აბსტრაქტი

88. von Wagner C, Smith S, Halligan S, et al. Patient acceptability of CT colonography compared with double contrast barium enema: results from a multicentre randomised controlled trial of symptomatic patients. Eur Radiol. 2011 May 31;21(10):2046-55. აბსტრაქტი

89. Rex DK, Rahmani EY, Haseman JH, et al. Relative sensitivity of colonoscopy and barium enema for detection of colorectal cancer in clinical practice. Gastroenterology. 1997 Jan;112(1):17-23. აბსტრაქტი

90. Rockey RC, Paulson E, Niedzwiecki D, et al. Analysis of air contrast barium enema, computed tomographic colonography, and colonoscopy: prospective comparison. Lancet. 2005 Jan 22-28;365(9456):305-11. აბსტრაქტი

91. Mulhall BP, Veerappan GR, Jackson JL. Meta-analysis: computed tomographic colonography. Ann Intern Med. 2005 Apr 19;142(8):635-50.სრული ტექსტი  აბსტრაქტი

92. Mang T. [Colorectal cancer: role of imaging in screening]. [in ger]. Radiologe. 2019 Jan;59(1):23-34.სრული ტექსტი  აბსტრაქტი

93. Glynne-Jones L, Wyrwicz E, Tiret G, et al. Rectal cancer: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2017;28(suppl 4):iv22-iv40.სრული ტექსტი

94. National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: rectal cancer [internet publication].სრული ტექსტი

95. Al-Sukhni E, Milot L, Fruitman M, et al. Diagnostic accuracy of MRI for assessment of T category, lymph node metastases, and circumferential resection margin involvement in patients with rectal cancer: a systematic review and meta-analysis. Ann Surg Oncol. 2012 Jul;19(7):2212-23. აბსტრაქტი

96. Watson AJ, Lolohea S, Robertson GM, et al. The role of positron emission tomography in the management of recurrent colorectal cancer: a review. Dis Colon Rectum. 2007 Jan;50(1):102-14. აბსტრაქტი

97. Zhang C, Chen Y, Xue H, et al. Diagnostic value of FDG-PET in recurrent colorectal carcinoma: a meta-analysis. Int J Cancer. 2009 Jan 1;124(1):167-73. აბსტრაქტი

98. Facey K, Bradbury I, Laking G, et al. Overview of the clinical effectiveness of positron emission tomography imaging in selected cancers. Health Technol Assess. 2007 Oct;11(44):iii-iv, xi-267.სრული ტექსტი  აბსტრაქტი

99. Moulton CA, Gu CS, Law CH, et al. Effect of PET before liver resection on surgical management for colorectal adenocarcinoma metastases: a randomized clinical trial. JAMA. 2014 May 14;311(18):1863-9.სრული ტექსტი  აბსტრაქტი

100. Flamen P, Hoekstra OS, Homans F, et al. Unexplained rising carcinoembryonic antigen (CEA) in the postoperative surveillance of colorectal cancer: the utility of positron emission tomography (PET). Eur J Cancer. 2001 May;37(7):862-9. აბსტრაქტი

101. Royal College of Radiologists, Royal College of Physicians. Evidence-based indications for the use of PET-CT in the United Kingdom 2022 [internet publication].სრული ტექსტი

102. Yu T, Meng N, Chi D, et al. Diagnostic value of (18)F-FDG PET/CT in detecting local recurrent colorectal cancer: a pooled analysis of 26 individual studies. Cell Biochem Biophys. 2015 Jun;72(2):443-51. აბსტრაქტი

103. National Institute for Health and Care Excellence. Quantitative faecal immunochemical testing to guide colorectal cancer pathway referral in primary care. Aug 2023 [internet publication].სრული ტექსტი

104. National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: colon cancer [internet publication].სრული ტექსტი

105. National Institute for Health and Care Excellence. Colorectal cancer. Quality standard (QS20). Feb 2022 [internet publication].სრული ტექსტი

106. du Toit J, Hamilton W, Barraclough K. Risk in primary care of colorectal cancer from new onset rectal bleeding: 10 year prospective study. BMJ. 2006 Jul 8;333(7558):69-70. აბსტრაქტი

107. McSherry CK, Cornell GN, Glenn F. Carcinoma of the colon and rectum. Ann Surg. 1969 Apr;169(4):502-9. აბსტრაქტი

108. Shallow TA, Wagner FB, Colcher RE. Clinical evaluation of 750 patients with colon cancer. Diagnostic survey and follow up covering a 15 year period. Ann Surg. 1955 Aug;142(2):164-75. აბსტრაქტი

109. Hamilton W, Sharp D. Diagnosis of colorectal cancer in primary care: the evidence base for guidelines. Fam Pract. 2004 Feb;21(1):99-106.სრული ტექსტი  აბსტრაქტი

110. Kanellos D, Kitsios G, Kanellos I, et al. Anemia as a symptom of right colon cancer. Tech Coloproctol. 2004 Nov;8 Suppl 1:s62-4. აბსტრაქტი

111. Vora P, Chapman A. Complications from radiographer-performed double contrast barium enemas. Clin Rad. 2004 Apr;59(4):364-8. აბსტრაქტი

112. Thoeni RF. Colorectal cancer. Radiologic staging. Radiol Clin North Am. 1997 Mar;35(2):457-85. აბსტრაქტი

113. Kwok H, Bissett IP, Hill GL. Preoperative staging of rectal cancer. Int J Colorectal Dis. 2000 Feb;15(1):9-20. აბსტრაქტი

114. Nikolaou S, Qiu S, Fiorentino F, et al. Systematic review of blood diagnostic markers in colorectal cancer. Tech Coloproctol. 2018 Jul 18;22(7):481-98.სრული ტექსტი  აბსტრაქტი

115. Nicholson BD, Shinkins B, Pathiraja I, et al. Blood CEA levels for detecting recurrent colorectal cancer. Cochrane Database Syst Rev. 2015 Dec 10;(12):CD011134.სრული ტექსტი  აბსტრაქტი

116. Shinkins B, Nicholson BD, James T, et al. What carcinoembryonic antigen level should trigger further investigation during colorectal cancer follow-up? A systematic review and secondary analysis of a randomised controlled trial. Health Technol Assess. 2017 Apr;21(22):1-60.სრული ტექსტი  აბსტრაქტი

117. Backes Y, Moss A, Reitsma JB, et al. Narrow band imaging, magnifying chromoendoscopy, and gross morphological features for the optical diagnosis of T1 colorectal cancer and deep submucosal invasion: a systematic review and meta-analysis. Am J Gastroenterol. 2016 Sep 20;112(1):54-64. აბსტრაქტი

118. Lacy BE, Mearin F, Chang L, et al. Bowel disorders. Gastroenterology. 2016 May;150(6):1393-407. აბსტრაქტი

119. Drossman DA, Camilleri M, Mayer EA, et al. AGA technical review on irritable bowel syndrome. Gastroenterology. 2002 Dec;123(6):2108-31.სრული ტექსტი  აბსტრაქტი

120. Cosnes J, Gower-Rousseau C, Seksik P, et al. Epidemiology and natural history of inflammatory bowel diseases. Gastroenterology. 2011 May;140(6):1785-94.სრული ტექსტი  აბსტრაქტი

121. Shergill AK, Lightdale JR, Bruining DH, et al; American Society for Gastrointestinal Endoscopy Standards of Practice Committee. The role of endoscopy in inflammatory bowel disease. Gastrointest Endosc. 2015 Mar 20;81(5):1101-21.e1-13.სრული ტექსტი  აბსტრაქტი

122. Public Health England. Bowel cancer screening: programme overview. Mar 2021 [internet publication].სრული ტექსტი

123. US Preventive Services Task Force., Davidson KW, Barry MJ, et al. Screening for colorectal cancer: US Preventive Services Task Force recommendation statement. JAMA. 2021 May 18;325(19):1965-77.სრული ტექსტი  აბსტრაქტი

124. Lieberman D, Ladabaum U, Brill JV, et al. Reducing the burden of colorectal cancer: AGA position statements. Gastroenterology. 2022 Aug;163(2):520-6.სრული ტექსტი  აბსტრაქტი

125. Patel SG, May FP, Anderson JC, et al. Updates on age to start and stop colorectal cancer screening: recommendations from the U.S. Multi-Society Task Force on Colorectal Cancer. Am J Gastroenterol. 2022 Jan 1;117(1):57-69.სრული ტექსტი  აბსტრაქტი

126. Wolf AM, Fontham ET, Church TR, et al. Colorectal cancer screening for average-risk adults: 2018 guideline update from the American Cancer Society. CA Cancer J Clin. 2018 May 30;68(4):250-81.სრული ტექსტი  აბსტრაქტი

127. Qaseem A, Harrod CS, Crandall CJ, et al. Screening for colorectal cancer in asymptomatic average-risk adults: a guidance statement from the American College of Physicians (version 2). Ann Intern Med. 2023 Aug;176(8):1092-100.სრული ტექსტი  აბსტრაქტი

128. Canadian Task Force on Preventive Health Care. Recommendations on screening for colorectal cancer in primary care. CMAJ. 2016 Mar 15;188(5):340-8.სრული ტექსტი  აბსტრაქტი

129. Buskermolen M, Cenin DR, Helsingen LM, et al. Colorectal cancer screening with faecal immunochemical testing, sigmoidoscopy or colonoscopy: a microsimulation modelling study. BMJ. 2019 Oct 2;367:l5383.სრული ტექსტი  აბსტრაქტი

130. Cairns SR, Scholefield JH, Steele RJ, et al; British Society of Gastroenterology; Association of Coloproctology for Great Britain and Ireland. Guidelines for colorectal cancer screening and surveillance in moderate and high risk groups (update from 2002). Gut. 2010 May;59(5):666-89. აბსტრაქტი

131. Syngal S, Brand RE, Church JM, et al. ACG clinical guideline: genetic testing and management of hereditary gastrointestinal cancer syndromes. Am J Gastroenterol. 2015 Feb 3;110(2):223-62.სრული ტექსტი  აბსტრაქტი

132. National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: genetic/familial high-risk assessment: colorectal [internet publication].სრული ტექსტი

133. Giardiello FM, Allen JI, Axilbund JE, et al. Guidelines on genetic evaluation and management of Lynch syndrome: a consensus statement by the US Multi-Society Task Force on Colorectal Cancer. Dis Colon Rectum. 2014 Aug;57(8):1025-48. აბსტრაქტი

134. Boland CR, Idos GE, Durno C, et al. Diagnosis and management of cancer risk in the gastrointestinal hamartomatous polyposis syndromes: recommendations from the US Multi-Society Task Force on Colorectal Cancer. Am J Gastroenterol. 2022 Jun 1;117(6):846-64.სრული ტექსტი  აბსტრაქტი

135. Rubin DT, Ananthakrishnan AN, Siegel CA, et al. ACG clinical guideline: ulcerative colitis in adults. Am J Gastroenterol. 2019 Mar;114(3):384-413.სრული ტექსტი  აბსტრაქტი

136. Murthy SK, Feuerstein JD, Nguyen GC, et al. AGA clinical practice update on endoscopic surveillance and management of colorectal dysplasia in inflammatory bowel diseases: expert review. Gastroenterology. 2021 Sep;161(3):1043-51.e4.სრული ტექსტი  აბსტრაქტი

137. van Gijn W, Gooiker GA, Wouters MW, et al. Volume and outcome in colorectal cancer surgery. Eur J Surg Oncol. 2010;36(suppl 1):S55-S63. აბსტრაქტი

138. Nelson H, Sargent DJ, Wieand HS, et al; Clinical Outcomes of Surgical Therapy Study Group. A comparison of laparoscopically assisted and open colectomy for colon cancer. N Engl J Med. 2004 May 13;350(20):2050-9.სრული ტექსტი  აბსტრაქტი

139. Buunen M, Veldkamp R, Hop WC, et al; Colon Cancer Laparoscopic or Open Resection Study Group. Survival after laparoscopic surgery versus open surgery for colon cancer: long-term outcome of a randomised clinical trial. Lancet Oncol. 2009 Jan;10(1):44-52. აბსტრაქტი

140. Green BL, Marshall HC, Collinson F, et al. Long-term follow-up of the Medical Research Council CLASICC trial of conventional versus laparoscopically assisted resection in colorectal cancer. Br J Surg. 2013 Jan;100(1):75-82.სრული ტექსტი  აბსტრაქტი

141. Kennedy RH, Francis EA, Wharton R, et al. Multicenter randomized controlled trial of conventional versus laparoscopic surgery for colorectal cancer within an enhanced recovery programme: EnROL. J Clin Oncol. 2014 Jun 10;32(17):1804-11.სრული ტექსტი  აბსტრაქტი

142. Lai JH, Law WL. Laparoscopic surgery for colorectal cancer. Br Med Bull. 2012 Oct 19;104:61-89.სრული ტექსტი  აბსტრაქტი

143. Anderson C, Uman G, Pigazzi A. Oncologic outcomes of laparoscopic surgery for rectal cancer: a systematic review and meta-analysis of the literature. Eur J Surg Oncol. 2008 Oct;34(10):1135-42. აბსტრაქტი

144. Ng SS, Lee JF, Yiu RY, et al. Long-term oncologic outcomes of laparoscopic versus open surgery for rectal cancer: a pooled analysis of 3 randomized controlled trials. Ann Surg. 2014 Jan;259(1):139-47. აბსტრაქტი

145. Vennix S, Pelzers L, Bouvy N, et al. Laparoscopic versus open total mesorectal excision for rectal cancer. Cochrane Database Syst Rev. 2014 Apr 15;(4):CD005200.სრული ტექსტი  აბსტრაქტი

146. Bonjer HJ, Deijen CL, Abis GA, et al; COLOR II Study Group. A randomized trial of laparoscopic versus open surgery for rectal cancer. N Engl J Med. 2015 Apr 2;372(14):1324-32.სრული ტექსტი  აბსტრაქტი

147. Jeong SY, Park JW, Nam BH, et al. Open versus laparoscopic surgery for mid-rectal or low-rectal cancer after neoadjuvant chemoradiotherapy (COREAN trial): survival outcomes of an open-label, non-inferiority, randomised controlled trial. Lancet Oncol. 2014 Jun;15(7):767-74. აბსტრაქტი

148. Fleshman J, Branda M, Sargent DJ, et al. Effect of laparoscopic-assisted resection vs. open resection of stage II or III rectal cancer on pathologic outcomes: the ACOSOG Z6051 randomized clinical trial. JAMA. 2015 Oct 6;314(13):1346-55. აბსტრაქტი

149. Prete FP, Pezzolla A, Prete F, et al. Robotic versus laparoscopic minimally invasive surgery for rectal cancer: a systematic review and meta-analysis of randomized controlled trials. Ann Surg. 2018 Jun;267(6):1034-46. აბსტრაქტი

150. Holmer C, Kreis ME. Systematic review of robotic low anterior resection for rectal cancer. Surg Endosc. 2017 Dec 7;32(2):569-81. აბსტრაქტი

151. Lee SH, Kim DH, Lim SW. Robotic versus laparoscopic intersphincteric resection for low rectal cancer: a systematic review and meta-analysis. Int J Colorectal Dis. 2018 Sep 5;33(12):1741-53. აბსტრაქტი

152. Jayne D, Pigazzi A, Marshall H, et al. Effect of robotic-assisted vs conventional laparoscopic surgery on risk of conversion to open laparotomy among patients undergoing resection for rectal cancer: the ROLARR randomized clinical trial. JAMA. 2017 Oct 24;318(16):1569-80.სრული ტექსტი  აბსტრაქტი

153. Spanjersberg WR, Reurings J, Keus F, et al. Fast track surgery versus conventional recovery strategies for colorectal surgery. Cochrane Database Syst Rev. 2011 Feb 16;(2):CD007635.სრული ტექსტი  აბსტრაქტი

154. van der Pas MH, Haglind E, Cuesta MA, et al. Laparoscopic versus open surgery for rectal cancer (COLOR II): short-term outcomes of a randomised, phase 3 trial. Lancet Oncol. 2013 Mar;14(3):210-8. აბსტრაქტი

155. Sajid MS, Farag S, Leung P, et al. Systematic review and meta-analysis of published trials comparing the effectiveness of transanal endoscopic microsurgery and radical resection in the management of early rectal cancer. Colorectal Dis. 2014 Jan;16(1):2-14. აბსტრაქტი

156. Sgourakis G, Lanitis S, Gockel I, et al. Transanal endoscopic microsurgery for T1 and T2 rectal cancers: a meta-analysis and meta-regression analysis of outcomes. Am Surg. 2011 Jun;77(6):761-72. აბსტრაქტი

157. Clancy C, Burke JP, Albert MR, et al. Transanal endoscopic microsurgery versus standard transanal excision for the removal of rectal neoplasms: a systematic review and meta-analysis. Dis Colon Rectum. 2015 Feb;58(2):254-61. აბსტრაქტი

158. Bax TW, McNevin MS. The value of diverting loop ileostomy on the high-risk colon and rectal anastomosis. Am J Surg. 2007 May;193(5):585-7; discussion 587-8. აბსტრაქტი

159. Hanna MH, Vinci A, Pigazzi A. Diverting ileostomy in colorectal surgery: when is it necessary? Langenbecks Arch Surg. 2015 Feb;400(2):145-52. აბსტრაქტი

160. Lynn PB, Renfro LA, Carrero XW, et al. Anorectal function and quality of life in patients with early stage rectal cancer treated with chemoradiation and local excision. Dis Colon Rectum. 2017 May;60(5):459-68. აბსტრაქტი

161. Rödel C, Liersch T, Becker H, et al; German Rectal Cancer Study Group. Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial. Lancet Oncol. 2012 Jul;13(7):679-87. აბსტრაქტი

162. Sauer R, Liersch T, Merkel S, et al. Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years. J Clin Oncol. 2012 Jun 1;30(16):1926-33. აბსტრაქტი

163. Fiorica F, Cartei F, Licata A, et al. Can chemotherapy concomitantly delivered with radiotherapy improve survival of patients with resectable rectal cancer? A meta-analysis of literature data. Cancer Treat Rev. 2010 Nov;36(7):539-49. აბსტრაქტი

164. Tiv M, Puyraveau M, Mineur L, et al. Long-term quality of life in patients with rectal cancer treated with preoperative (chemo)-radiotherapy within a randomized trial. Cancer Radiother. 2010 Oct;14(6-7):530-4. აბსტრაქტი

165. Conroy T, Bosset JF, Etienne PL, et al. Neoadjuvant chemotherapy with FOLFIRINOX and preoperative chemoradiotherapy for patients with locally advanced rectal cancer (UNICANCER-PRODIGE 23): a multicentre, randomised, open-label, phase 3 trial. Lancet Oncol. 2021 May;22(5):702-15. აბსტრაქტი

166. van Gijn W, Marijnen CA, Nagtegaal ID, et al; Dutch Colorectal Cancer Group. Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer: 12-year follow-up of the multicentre, randomised controlled TME trial. Lancet Oncol. 2011 Jun;12(6):575-82. აბსტრაქტი

167. Pettersson D, Cedermark B, Holm T, et al. Interim analysis of the Stockholm III trial of preoperative radiotherapy regimens for rectal cancer. Br J Surg. 2010 Apr;97(4):580-7. აბსტრაქტი

168. Ngan SY, Burmeister B, Fisher RJ, et al. Randomized trial of short-course radiotherapy versus long-course chemoradiation comparing rates of local recurrence in patients with T3 rectal cancer: Trans-Tasman Radiation Oncology Group trial 01.04. J Clin Oncol. 2012 Nov 1;30(31):3827-33. აბსტრაქტი

169. Bujko K, Nowacki MP, Nasierowska-Guttmejer A, et al. Sphincter preservation following preoperative radiotherapy for rectal cancer: report of a randomised trial comparing short-term radiotherapy vs. conventionally fractionated radiochemotherapy. Radiother Oncol. 2004 Jul;72(1):15-24. აბსტრაქტი

170. van den Broek CB, Vermeer TA, Bastiaannet E, et al. Impact of the interval between short-course radiotherapy and surgery on outcomes of rectal cancer patients. Eur J Cancer. 2013 Oct;49(15):3131-9.სრული ტექსტი  აბსტრაქტი

171. Erlandsson J, Holm T, Pettersson D, et al. Optimal fractionation of preoperative radiotherapy and timing to surgery for rectal cancer (Stockholm III): a multicentre, randomised, non-blinded, phase 3, non-inferiority trial. Lancet Oncol. 2017 Mar;18(3):336-46. აბსტრაქტი

172. Bujko K, Glynne-Jones R, Bujko M. Does adjuvant fluoropyrimidine-based chemotherapy provide a benefit for patients with resected rectal cancer who have already received neoadjuvant radiochemotherapy? A systematic review of randomised trials. Ann Oncol. 2010 Sep;21(9):1743-50.სრული ტექსტი  აბსტრაქტი

173. Bosset JF, Calais G, Mineur L, et al; EORTC Radiation Oncology Group. Fluorouracil-based adjuvant chemotherapy after preoperative chemoradiotherapy in rectal cancer: long-term results of the EORTC 22921 randomised study. Lancet Oncol. 2014 Feb;15(2):184-90. აბსტრაქტი

174. Cancer Care Ontario. Preoperative or postoperative therapy for the management of patients with stage II or III rectal cancer. Mar 2019 [internet publication].სრული ტექსტი

175. Hong YS, Kim SY, Lee JS, et al. Oxaliplatin-based adjuvant chemotherapy for rectal cancer after preoperative chemoradiotherapy (ADORE): long-term results of a randomized controlled trial. J Clin Oncol. 2019 Nov 20;37(33):3111-23.სრული ტექსტი  აბსტრაქტი

176. Kim TW, Lee JH, Lee JH, et al. Randomized trial of postoperative adjuvant therapy in stage II and III rectal cancer to define the optimal sequence of chemotherapy and radiotherapy: 10-year follow-up. Int J Radiat Oncol Biol Phys. 2011 Nov 15;81(4):1025-31. აბსტრაქტი

177. Cercek A, Roxburgh CSD, Strombom P, et al. Adoption of total neoadjuvant therapy for locally advanced rectal cancer. JAMA Oncol. 2018 Jun 14;4(6):e180071.სრული ტექსტი  აბსტრაქტი

178. de Mestier L, Manceau G, Neuzillet C, et al. Primary tumor resection in colorectal cancer with unresectable synchronous metastases: a review. World J Gastrointest Oncol. 2014 Jun 15;6(6):156-69.სრული ტექსტი  აბსტრაქტი

179. Choti MA, Sitzmann JV, Tiburi MF, et al. Trends in long term survival following liver resection for hepatic colorectal metastases. Ann Surg. 2002 Jun;235(6):759-66.სრული ტექსტი  აბსტრაქტი

180. Cummings LC, Payes JD, Cooper GS. Survival after hepatic resection in metastatic colorectal cancer: a population-based study. Cancer. 2007 Feb 15;109(4):718-26.სრული ტექსტი  აბსტრაქტი

181. Cao G, Cheng D, Ye L, et al. Surgical resection of pulmonary metastases from colorectal cancer: 11 years of experiences. PLoS One. 2017 Apr 10;12(4):e0175284.სრული ტექსტი  აბსტრაქტი

182. Groot Koerkamp B, Sadot E, Kemeny NE, et al. Perioperative hepatic arterial infusion pump chemotherapy is associated with longer survival after resection of colorectal liver metastases: a propensity score analysis. J Clin Oncol. 2017 Jun 10;35(17):1938-44.სრული ტექსტი  აბსტრაქტი

183. Pozzo C, Basso M, Cassano A, et al. Neoadjuvant treatment of unresectable liver disease with irinotecan and 5-fluorouracil plus folinic acid in colorectal cancer patients. Ann Oncol. 2004 Jun;15(6):933-9.სრული ტექსტი  აბსტრაქტი

184. Ozair A, Collings A, Adams AM, et al. Minimally invasive versus open hepatectomy for the resection of colorectal liver metastases: a systematic review and meta-analysis. Surg Endosc. 2022 Nov;36(11):7915-37. აბსტრაქტი

185. Vreeland TJ, Collings AT, Ozair A, et al. SAGES/AHPBA guidelines for the use of minimally invasive surgery for the surgical treatment of colorectal liver metastases (CRLM). Surg Endosc. 2023 Apr;37(4):2508-16. აბსტრაქტი

186. Abdalla M, Collings AT, Dirks R, et al. Surgical approach to microwave and radiofrequency liver ablation for hepatocellular carcinoma and colorectal liver metastases less than 5 cm: a systematic review and meta-analysis. Surg Endosc. 2023 May;37(5):3340-53. აბსტრაქტი

187. Ceppa EP, Collings AT, Abdalla M, et al. SAGES/AHPBA guidelines for the use of microwave and radiofrequency liver ablation for the surgical treatment of hepatocellular carcinoma or colorectal liver metastases less than 5 cm. Surg Endosc. 2023 Dec;37(12):8991-9000. აბსტრაქტი

188. Hall B, Padussis J, Foster JM. Cytoreduction and hyperthermic intraperitoneal chemotherapy in the management of colorectal peritoneal metastasis. Surg Clin North Am. 2017 Jun;97(3):671-82. აბსტრაქტი

189. Baratti D, Kusamura S, Pietrantonio F, et al. Progress in treatments for colorectal cancer peritoneal metastases during the years 2010-2015. A systematic review. Crit Rev Oncol Hematol. 2016 Jan 22;100:209-22. აბსტრაქტი

190. Haram A, Boland MR, Kelly ME, et al. The prognostic value of neutrophil-to-lymphocyte ratio in colorectal cancer: a systematic review. J Surg Oncol. 2017 Jan 20;115(4):470-9. აბსტრაქტი

191. Min GT, Wang YH, Yao N, et al. The prognostic role of pretreatment platelet-to-lymphocyte ratio as predictors in patients with colorectal cancer: a meta-analysis. Biomark Med. 2016 Dec 5;11(1):87-97. აბსტრაქტი

192. Tan D, Fu Y, Su Q, et al. Prognostic role of platelet-lymphocyte ratio in colorectal cancer: a systematic review and meta-analysis. Medicine (Baltimore). 2016 Jun;95(24):e3837.სრული ტექსტი  აბსტრაქტი

193. Tsai PL, Su WJ, Leung WH, et al. Neutrophil-lymphocyte ratio and CEA level as prognostic and predictive factors in colorectal cancer: a systematic review and meta-analysis. J Cancer Res Ther. 2016 Apr-Jun;12(2):582-9.სრული ტექსტი  აბსტრაქტი

194. Zhu L, Dong C, Cao Y, et al. Prognostic role of BRAF mutation in stage II/III colorectal cancer receiving curative resection and adjuvant chemotherapy: a meta-analysis based on randomized clinical trials. PLoS One. 2016 May 3;11(5):e0154795.სრული ტექსტი  აბსტრაქტი

195. Pikoulis E, Margonis GA, Andreatos N, et al. Prognostic role of BRAF mutations in colorectal cancer liver metastases. Anticancer Res. 2016 Sep;36(9):4805-11.სრული ტექსტი  აბსტრაქტი

196. Li ZN, Zhao L, Yu LF, et al. BRAF and KRAS mutations in metastatic colorectal cancer: future perspectives for personalized therapy. Gastroenterol Rep (Oxf). 2020 Jun;8(3):192-205.სრული ტექსტი  აბსტრაქტი

197. Costas-Chavarri A, Nandakumar G, Temin S, et al. Treatment of patients with early-stage colorectal cancer: ASCO resource-stratified guideline. J Glob Oncol. 2019 Feb;5:1-19.სრული ტექსტი  აბსტრაქტი

198. Maak M, Simon I, Nitsche U, et al. Independent validation of a prognostic genomic signature (ColoPrint) for patients with stage II colon cancer. Ann Surg. 2013 Jun;257(6):1053-8. აბსტრაქტი

199. Venook AP, Niedzwiecki D, Lopatin M, et al. Biologic determinants of tumor recurrence in stage II colon cancer: validation study of the 12-gene recurrence score in cancer and leukemia group B (CALGB) 9581. J Clin Oncol. 2013 May 10;31(14):1775-81.სრული ტექსტი  აბსტრაქტი

200. Meyers BM, Cosby R, Quereshy F, et al. Adjuvant systemic chemotherapy for stages II and III colon cancer after complete resection: a clinical practice guideline. Curr Oncol. 2016 Dec 21;23(6):418-24.სრული ტექსტი  აბსტრაქტი

201. Lieu C, Kennedy EB, Bergsland E, et al. Duration of oxaliplatin-containing adjuvant therapy for stage III colon cancer: ASCO clinical practice guideline. J Clin Oncol. 2019 Jun 1;37(16):1436-47.სრული ტექსტი  აბსტრაქტი

202. André T, Boni C, Navarro M, et al. Improved overall survival with oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment in stage II or III colon cancer in the MOSAIC trial. J Clin Oncol. 2009 Jul 1;27(19):3109-16.სრული ტექსტი  აბსტრაქტი

203. Baxter NN, Kennedy EB, Bergsland E, et al. Adjuvant therapy for stage II colon cancer: ASCO guideline update. J Clin Oncol. 2022 Mar 10;40(8):892-910.სრული ტექსტი  აბსტრაქტი

204. André T, de Gramont A, Vernerey D, et al. Adjuvant fluorouracil, leucovorin, and oxaliplatin in stage II to III colon cancer: updated 10-year survival and outcomes according to BRAF mutation and mismatch repair status of the MOSAIC study. J Clin Oncol. 2015 Dec 10;33(35):4176-87. აბსტრაქტი

205. Loree JM, Sha A, Soleimani M, et al. Survival impact of CAPOX versus FOLFOX in the adjuvant treatment of stage III colon cancer. Clin Colorectal Cancer. 2018 Feb 7;17(2):156-63. აბსტრაქტი

206. Tournigand C, André T, Bonnetain F, et al. Adjuvant therapy with fluorouracil and oxaliplatin in stage II and elderly patients (between ages 70 and 75 years) with colon cancer: subgroup analyses of the Multicenter International Study of Oxaliplatin, Fluorouracil, and Leucovorin in the Adjuvant Treatment of Colon Cancer trial. J Clin Oncol. 2012 Sep 20;30(27):3353-60. აბსტრაქტი

207. Sargent DJ, Marsoni S, Monges G, et al. Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer. J Clin Oncol. 2010 Jul 10;28(20):3219-26.სრული ტექსტი  აბსტრაქტი

208. Des Guetz G, Nicolas P, Perret GY, et al. Does delaying adjuvant chemotherapy after curative surgery for colorectal cancer impair survival? A meta-analysis. Eur J Cancer. 2010 Apr;46(6):1049-55. აბსტრაქტი

209. Biagi JJ, Raphael MJ, Mackillop WJ, et al. Association between time to initiation of adjuvant chemotherapy and survival in colorectal cancer. JAMA. 2011 Jun 8;305(22):2335-42. აბსტრაქტი

210. Lopez NE, Weiss AC, Robles J, et al. A systematic review of clinically available gene expression profiling assays for stage II colorectal cancer: initial steps toward genetic staging. Am J Surg. 2016 Aug 1;212(4):700-14. აბსტრაქტი

211. Morton D, Seymour M, Magill L, et al. Preoperative chemotherapy for operable colon cancer: mature results of an international randomized controlled trial. J Clin Oncol. 2023 Mar 10;41(8):1541-52.სრული ტექსტი  აბსტრაქტი

212. Clark ME, Smith RR. Liver-directed therapies in metastatic colorectal cancer. J Gastrointest Oncol. 2014 Oct;5(5):374-87.სრული ტექსტი  აბსტრაქტი

213. De Groote K, Prenen H. Intrahepatic therapy for liver-dominant metastatic colorectal cancer. World J Gastrointest Oncol. 2015 Sep 15;7(9):148-52.სრული ტექსტი  აბსტრაქტი

214. Jones C, Badger SA, Ellis G. The role of microwave ablation in the management of hepatic colorectal metastases. Surgeon. 2011 Feb;9(1):33-7. აბსტრაქტი

215. Fuchs CS, Marshall J, Barrueco J. Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: updated results from the BICC-C study. J Clin Oncol. 2008 Feb 1;26(4):689-90. აბსტრაქტი

216. Tournigand C, Cervantes A, Figer A, et al. OPTIMOX1: a randomized study of FOLFOX4 or FOLFOX7 with oxaliplatin in a stop-and-go fashion in advanced colorectal cancer - a GERCOR study. J Clin Oncol. 2006 Jan 20;24(3):394-400.სრული ტექსტი  აბსტრაქტი

217. Venook AP, Niedzwiecki D, Lenz HJ, et al. Effect of first-line chemotherapy combined with cetuximab or bevacizumab on overall survival in patients with KRAS wild-type advanced or metastatic colorectal cancer: a randomized clinical trial. JAMA. 2017 Jun 20;317(23):2392-401.სრული ტექსტი  აბსტრაქტი

218. Chiorean EG, Nandakumar G, Fadelu T, et al. Treatment of patients with late-stage colorectal cancer: ASCO resource-stratified guideline. JCO Glob Oncol. 2020 Mar;6:414-38.სრული ტექსტი  აბსტრაქტი

219. Cassidy J, Clarke S, Díaz-Rubio E, et al. Randomized phase III study of capecitabine plus oxaliplatin compared with fluorouracil/folinic acid plus oxaliplatin as first-line therapy for metastatic colorectal cancer. J Clin Oncol. 2008 Apr 20;26(12):2006-12.სრული ტექსტი  აბსტრაქტი

220. Rothenberg ML, Cox JV, Butts C, et al. Capecitabine plus oxaliplatin (XELOX) versus 5-fluorouracil/folinic acid plus oxaliplatin (FOLFOX-4) as second-line therapy in metastatic colorectal cancer: a randomized phase III noninferiority study. Ann Oncol. 2008 Oct;19(10):1720-6.სრული ტექსტი  აბსტრაქტი

221. Marques RP, Duarte GS, Sterrantino C, et al. Triplet (FOLFOXIRI) versus doublet (FOLFOX or FOLFIRI) backbone chemotherapy as first-line treatment of metastatic colorectal cancer: a systematic review and meta-analysis. Crit Rev Oncol Hematol. 2017 Aug 25;118:54-62. აბსტრაქტი

222. Fuchs CS, Marshall J, Mitchell E, et al. Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: results from the BICC-C Study. J Clin Oncol. 2007 Oct 20;25(30):4779-86.სრული ტექსტი  აბსტრაქტი

223. Saltz LB, Clarke S, Díaz-Rubio E, et al. Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study. J Clin Oncol. 2008 Apr 20;26(12):2013-9. აბსტრაქტი

224. Giantonio BJ, Catalano PJ, Meropol NJ, et al; Eastern Cooperative Oncology Group Study E3200. Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200. J Clin Oncol. 2007 Apr 20;25(12):1539-44. აბსტრაქტი

225. Bennouna J, Sastre J, Arnold D, et al. Continuation of bevacizumab after first progression in metastatic colorectal cancer (ML18147): a randomised phase 3 trial. Lancet Oncol. 2013 Jan;14(1):29-37. აბსტრაქტი

226. Botrel TE, Clark LG, Paladini L, et al. Efficacy and safety of bevacizumab plus chemotherapy compared to chemotherapy alone in previously untreated advanced or metastatic colorectal cancer: a systematic review and meta-analysis. BMC Cancer. 2016 Aug 24;16:677.სრული ტექსტი  აბსტრაქტი

227. Pei X, Liu Y, Sun L, et al. Outcome of molecular targeted agents plus chemotherapy for second-line therapy of metastatic colorectal cancer: a meta-analysis of randomized trials. Clin Colorectal Cancer. 2016 Mar 31;15(4):e149-56. აბსტრაქტი

228. Cremolini C, Antoniotti C, Stein A, et al. Individual patient data meta-analysis of FOLFOXIRI plus bevacizumab versus doublets plus bevacizumab as initial therapy of unresectable metastatic colorectal cancer. J Clin Oncol. 2020 Aug 20;JCO2001225. აბსტრაქტი

229. Tang W, Ren L, Liu T, et al. Bevacizumab plus mFOLFOX6 versus mFOLFOX6 alone as first-line treatment for RAS mutant unresectable colorectal liver-limited metastases: the BECOME randomized controlled trial. J Clin Oncol. 2020 Sep 20;38(27):3175-84.სრული ტექსტი  აბსტრაქტი

230. Zhu X, Tian X, Yu C, et al. Increased risk of hemorrhage in metastatic colorectal cancer patients treated with bevacizumab: an updated meta-analysis of 12 randomized controlled trials. Medicine (Baltimore). 2016 Aug;95(34):e4232.სრული ტექსტი  აბსტრაქტი

231. Van Cutsem E, Tabernero J, Lakomy R, et al. Addition of aflibercept to fluorouracil, leucovorin, and irinotecan improves survival in a phase III randomized trial in patients with metastatic colorectal cancer previously treated with an oxaliplatin-based regimen. J Clin Oncol. 2012 Oct 1;30(28):3499-506. აბსტრაქტი

232. Tabernero J, Yoshino T, Cohn AL, et al; RAISE Study Investigators. Ramucirumab versus placebo in combination with second-line FOLFIRI in patients with metastatic colorectal carcinoma that progressed during or after first-line therapy with bevacizumab, oxaliplatin, and a fluoropyrimidine (RAISE): a randomised, double-blind, multicentre, phase 3 study. Lancet Oncol. 2015 May;16(5):499-508. აბსტრაქტი

233. Chen Q, Cheng M, Wang Z, et al. The efficacy and safety of panitumumab plus irinotecan-based chemotherapy in the treatment of metastatic colorectal cancer: a meta-analysis. Medicine (Baltimore). 2016 Dec;95(50):e5284.სრული ტექსტი  აბსტრაქტი

234. Heinemann V, Rivera F, O'Neil BH, et al. A study-level meta-analysis of efficacy data from head-to-head first-line trials of epidermal growth factor receptor inhibitors versus bevacizumab in patients with RAS wild-type metastatic colorectal cancer. Eur J Cancer. 2016 Sep 1;67:11-20.სრული ტექსტი  აბსტრაქტი

235. Yang YF, Wang GY, He JL, et al. Overall survival of patients with KRAS wild-type tumor treated with FOLFOX/FORFIRI±cetuximab as the first-line treatment for metastatic colorectal cancer: a meta-analysis. Medicine (Baltimore). 2017 Mar;96(12):e6335.სრული ტექსტი  აბსტრაქტი

236. Sepulveda AR, Hamilton SR, Allegra CJ, et al. Molecular biomarkers for the evaluation of colorectal cancer: guideline from the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and American Society of Clinical Oncology. Arch Pathol Lab Med. 2017 Feb 6;141(5):625-57.სრული ტექსტი  აბსტრაქტი

237. Pietrantonio F, Cremolini C, Petrelli F, et al. First-line anti-EGFR monoclonal antibodies in panRAS wild-type metastatic colorectal cancer: a systematic review and meta-analysis. Crit Rev Oncol Hematol. 2015 Jun 5;96(1):156-66. აბსტრაქტი

238. Modest DP, Karthaus M, Fruehauf S, et al. Panitumumab plus fluorouracil and folinic acid versus fluorouracil and folinic acid alone as maintenance therapy in RAS wild-type metastatic colorectal cancer: The randomized PANAMA trial (AIO KRK 0212). J Clin Oncol. 2021 Sep 17;JCO2101332.სრული ტექსტი  აბსტრაქტი

239. Loupakis F, Cremolini C, Masi G, et al. Initial therapy with FOLFOXIRI and bevacizumab for metastatic colorectal cancer. N Engl J Med. 2014 Oct 23;371(17):1609-18.სრული ტექსტი  აბსტრაქტი

240. Hochster HS, Grothey A, Hart L, et al. Improved time to treatment failure with an intermittent oxaliplatin strategy: results of CONcePT. Ann Oncol. 2014 Jun;25(6):1172-8.სრული ტექსტი  აბსტრაქტი

241. Yalcin S, Uslu R, Dane F, et al. Bevacizumab + capecitabine as maintenance therapy after initial bevacizumab + XELOX treatment in previously untreated patients with metastatic colorectal cancer: phase III 'Stop and Go' study results - a Turkish Oncology Group Trial. Oncology. 2013;85(6):328-35.სრული ტექსტი  აბსტრაქტი

242. Simkens LH, van Tinteren H, May A, et al. Maintenance treatment with capecitabine and bevacizumab in metastatic colorectal cancer (CAIRO3): a phase 3 randomised controlled trial of the Dutch Colorectal Cancer Group. Lancet. 2015 May 9;385(9980):1843-52. აბსტრაქტი

243. Aparicio T, Ghiringhelli F, Boige V, et al. Bevacizumab maintenance versus no maintenance during chemotherapy-free intervals in metastatic colorectal cancer: a randomized phase III trial (PRODIGE 9). J Clin Oncol. 2018 Mar 1;36(7):674-81.სრული ტექსტი  აბსტრაქტი

244. Adams RA, Fisher DJ, Graham J, et al. Capecitabine versus active monitoring in stable or responding metastatic colorectal cancer after 16 weeks of first-line therapy: results of the randomized FOCUS4-N trial. J Clin Oncol. 2021 Sep 13;JCO2101436.სრული ტექსტი  აბსტრაქტი

245. Ma H, Wu X, Tao M, et al. Efficacy and safety of bevacizumab-based maintenance therapy in metastatic colorectal cancer: a meta-analysis. Medicine (Baltimore). 2019 Dec;98(50):e18227.სრული ტექსტი  აბსტრაქტი

246. Xu W, Gong Y, Kuang M, et al. Survival benefit and safety of bevacizumab in combination with erlotinib as maintenance therapy in patients with metastatic colorectal cancer: a meta-analysis. Clin Drug Investig. 2017 Feb;37(2):155-65. აბსტრაქტი

247. Lo Nigro C, Ricci V, Vivenza D, et al. Prognostic and predictive biomarkers in metastatic colorectal cancer anti-EGFR therapy. World J Gastroenterol. 2016 Aug 14;22(30):6944-54.სრული ტექსტი  აბსტრაქტი

248. Grothey A, Van Cutsem E, Sobrero A, et al; CORRECT Study Group. Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial. Lancet. 2013 Jan 26;381(9863):303-12. აბსტრაქტი

249. Mercier J, Voutsadakis IA. A systematic review and meta-analysis of retrospective series of regorafenib for treatment of metastatic colorectal cancer. Anticancer Res. 2017 Nov;37(11):5925-34.სრული ტექსტი  აბსტრაქტი

250. Røed Skårderud M, Polk A, Kjeldgaard Vistisen K, et al. Efficacy and safety of regorafenib in the treatment of metastatic colorectal cancer: a systematic review. Cancer Treat Rev. 2017 Nov 10;62:61-73. აბსტრაქტი

251. National Institute for Health and Care Excellence. Regorafenib for previously treated metastatic colorectal cancer. Feb 2023 [internet publication].სრული ტექსტი

252. Mayer RJ, Van Cutsem E, Falcone A, et al; RECOURSE Study Group. Randomized trial of TAS-102 for refractory metastatic colorectal cancer. N Engl J Med. 2015 May 14;372(20):1909-19.სრული ტექსტი  აბსტრაქტი

253. André T, Shiu KK, Kim TW, et al. Pembrolizumab in microsatellite-instability-high advanced colorectal cancer. N Engl J Med. 2020 Dec 3;383(23):2207-18. აბსტრაქტი

254. Andre T, Amonkar M, Norquist JM, et al. Health-related quality of life in patients with microsatellite instability-high or mismatch repair deficient metastatic colorectal cancer treated with first-line pembrolizumab versus chemotherapy (KEYNOTE-177): an open-label, randomised, phase 3 trial. Lancet Oncol. 2021 May;22(5):665-77. აბსტრაქტი

255. Diaz LA Jr, Shiu KK, Kim TW, et al. Pembrolizumab versus chemotherapy for microsatellite instability-high or mismatch repair-deficient metastatic colorectal cancer (KEYNOTE-177): final analysis of a randomised, open-label, phase 3 study. Lancet Oncol. 2022 May;23(5):659-70. აბსტრაქტი

256. Overman MJ, Lonardi S, Wong KY, et al. Durable clinical benefit with nivolumab plus ipilimumab in DNA mismatch repair-deficient/microsatellite instability-high metastatic colorectal cancer. J Clin Oncol. 2018 Jan 20;36(8):773-9.სრული ტექსტი  აბსტრაქტი

257. ClinicalTrials.gov. Study of induction PD-1 blockade in subjects with locally advanced mismatch repair deficient solid tumors. Oct 2022 [internet publication].სრული ტექსტი

258. Cercek A, Lumish M, Sinopoli J, et al. PD-1 blockade in mismatch repair-deficient, locally advanced rectal cancer. N Engl J Med. 2022 Jun 23;386(25):2363-76. აბსტრაქტი

259. Zhou X, Yao Z, Bai H, et al. Treatment-related adverse events of PD-1 and PD-L1 inhibitor-based combination therapies in clinical trials: a systematic review and meta-analysis. Lancet Oncol. 2021 Sep;22(9):1265-74. აბსტრაქტი

260. National Institute for Health and Care Excellence. Encorafenib plus cetuximab for previously treated BRAF V600E mutation-positive metastatic colorectal cancer. Jan 2021 [internet publication].სრული ტექსტი

261. Kopetz S, Grothey A, Yaeger R, et al. Encorafenib, binimetinib, and cetuximab in BRAF V600E-mutated colorectal cancer. N Engl J Med. 2019 Oct 24;381(17):1632-43.სრული ტექსტი  აბსტრაქტი

262. Farago AF, Demetri GD. Larotrectinib, a selective tropomyosin receptor kinase inhibitor for adult and pediatric tropomyosin receptor kinase fusion cancers. Future Oncol. 2020 Mar;16(9):417-25. აბსტრაქტი

263. Federman N, McDermott R. Larotrectinib, a highly selective tropomyosin receptor kinase (TRK) inhibitor for the treatment of TRK fusion cancer. Expert Rev Clin Pharmacol. 2019 Oct;12(10):931-9.სრული ტექსტი  აბსტრაქტი

264. Doebele RC, Drilon A, Paz-Ares L, et al. Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1-2 trials. Lancet Oncol. 2020 Feb;21(2):271-82. აბსტრაქტი

265. Mocellin S, Baretta Z, Roqué I, et al. Second-line systemic therapy for metastatic colorectal cancer. Cochrane Database Syst Rev. 2017 Jan 27;(1):CD006875.სრული ტექსტი  აბსტრაქტი

266. Sobrero AF, Maurel J, Fehrenbacher L, et al. EPIC: phase III trial of cetuximab plus irinotecan after fluoropyrimidine and oxaliplatin failure in patients with metastatic colorectal cancer. J Clin Oncol. 2008 May 10;26(14):2311-9. აბსტრაქტი

267. Aldrich J, Pundole X, Tummala S, et al. Inflammatory myositis in cancer patients receiving immune checkpoint inhibitors. Arthritis Rheumatol. 2021 May;73(5):866-74.სრული ტექსტი  აბსტრაქტი

268. Poston GJ, Adam R, Alberts S, et al. OncoSurge: a strategy for improving resectability with curative intent in metastatic colorectal cancer. J Clin Oncol. 2005 Oct 1;23(28):7125-34.სრული ტექსტი  აბსტრაქტი

269. Douillard JY, Oliner KS, Siena S, et al. Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer. N Engl J Med. 2013 Sep 12;369(11):1023-34.სრული ტექსტი  აბსტრაქტი

270. Van Cutsem E, Lenz HJ, Köhne CH, et al. Fluorouracil, leucovorin, and irinotecan plus cetuximab treatment and RAS mutations in colorectal cancer. J Clin Oncol. 2015 Mar 1;33(7):692-700.სრული ტექსტი  აბსტრაქტი

271. Bjørn MX, Perdawood SK. Transanal total mesorectal excision--a systematic review. Dan Med J. 2015 Jul;62(7):A5105.სრული ტექსტი  აბსტრაქტი

272. Lau SYC, Choy KT, Yang TWW, et al. Defining the learning curve of transanal total mesorectal excision: a systematic review and meta-analysis. ANZ J Surg. 2022 Mar;92(3):355-64. აბსტრაქტი

273. Butterworth JW, Butterworth WA, Meyer J, et al. A systematic review and meta-analysis of robotic-assisted transabdominal total mesorectal excision and transanal total mesorectal excision: which approach offers optimal short-term outcomes for mid-to-low rectal adenocarcinoma? Tech Coloproctol. 2021 Nov;25(11):1183-98. აბსტრაქტი

274. National Institute for Health and Care Excellence. Transanal total mesorectal excision for rectal cancer. Dec 2021 [internet publication].სრული ტექსტი

275. Townsend AR, Chong LC, Karapetis C, et al. Selective internal radiation therapy for liver metastases from colorectal cancer. Cancer Treat Rev. 2016 Nov;50:148-54. აბსტრაქტი

276. van Hazel GA, Heinemann V, Sharma NK, et al. SIRFLOX: randomized phase III trial comparing first-line mFOLFOX6 (plus or minus bevacizumab) versus mFOLFOX6 (plus or minus bevacizumab) plus selective internal radiation therapy in patients with metastatic colorectal cancer. J Clin Oncol. 2016 May 20;34(15):1723-31.სრული ტექსტი  აბსტრაქტი

277. Van Hazel G, Blackwell A, Anderson J, et al. Randomised phase 2 trial of SIR-Spheres plus fluorouracil/leucovorin chemotherapy versus fluorouracil/leucovorin chemotherapy alone in advanced colorectal cancer. J Surg Oncol. 2004 Nov 1;88(2):78-85. აბსტრაქტი

278. Gray B, Van Hazel G, Hope M, et al. Randomised trial of SIR-Spheres plus chemotherapy vs. chemotherapy alone for treating patients with liver metastases from primary large bowel cancer. Ann Oncol. 2001 Dec;12(12):1711-20. აბსტრაქტი

279. Hendlisz A, Van den Eynde M, Peeters M, et al. Phase III trial comparing protracted intravenous fluorouracil infusion alone or with yttrium-90 resin microspheres radioembolization for liver-limited metastatic colorectal cancer refractory to standard chemotherapy. J Clin Oncol. 2010 Aug 10;28(23):3687-94.სრული ტექსტი  აბსტრაქტი

280. Mulcahy MF, Mahvash A, Pracht M, et al. Radioembolization with chemotherapy for colorectal liver metastases: a randomized, open-label, international, multicenter, phase III trial. J Clin Oncol. 2021 Sep 20;JCO2101839.სრული ტექსტი  აბსტრაქტი

281. Wasan HS, Gibbs P, Sharma NK, et al. First-line selective internal radiotherapy plus chemotherapy versus chemotherapy alone in patients with liver metastases from colorectal cancer (FOXFIRE, SIRFLOX, and FOXFIRE-Global): a combined analysis of three multicentre, randomised, phase 3 trials. Lancet Oncol. 2017 Sep;18(9):1159-71.სრული ტექსტი  აბსტრაქტი

282. ClinicalTrials.gov. SOX versus XELOX as adjuvant chemotherapy for stage III colorectal cancer patients. ClinicalTrials.gov identifier: NCT03448549. Mar 2020 [internet publication].სრული ტექსტი

283. ClinicalTrials.gov.​ Tucatinib Plus trastuzumab in patients With HER2+ colorectal cancer. Feb 2023 [internet publication].სრული ტექსტი

284. Shirley M. Fruquintinib: First global approval. Drugs. 2018 Nov;78(16):1757-61. აბსტრაქტი

285. Li J, Qin S, Xu RH, et al. Effect of fruquintinib vs placebo on overall survival in patients with previously treated metastatic colorectal cancer: the FRESCO randomized clinical trial. JAMA. 2018 Jun 26;319(24):2486-96.სრული ტექსტი  აბსტრაქტი

286. ClinicalTrials.gov. ​A study of efficacy and safety of fruquintinib (HMPL-013) in patients with metastatic colorectal cancer (FRESCO-2). Mar 2023 [internet publication].სრული ტექსტი

287. Dasari A, Lonardi S, Garcia-Carbonero R, et al. Fruquintinib versus placebo in patients with refractory metastatic colorectal cancer (FRESCO-2): an international, multicentre, randomised, double-blind, phase 3 study. Lancet. 2023 Jul 1;402(10395):41-53. აბსტრაქტი

288. ClinicalTrials.gov. ​A study of botensilimab and balstilimab for the treatment of colorectal cancer. Apr 2023 [internet publication].სრული ტექსტი

289. Heresbach D, Manfredi S, D'halluin PN, et al. Review in depth and meta-analysis of controlled trials on colorectal cancer screening by faecal occult blood test. Eur J Gastroenterol Hepatol. 2006 Apr;18(4):427-33. აბსტრაქტი

290. Burch JA, Soares-Weiser K, St John DJ, et al. Diagnostic accuracy of faecal occult blood tests used in screening for colorectal cancer: a systematic review. J Med Screen. 2007;14(3):132-7.სრული ტექსტი  აბსტრაქტი

291. O'Connell JB, Maggard MA, Ko CY. Colon cancer survival rates with the new American Joint Committee on Cancer sixth edition staging. J Natl Cancer Inst. 2004 Oct 6;96(19):1420-5.სრული ტექსტი  აბსტრაქტი

292. Gebremedhn EG, Shortland PJ, Mahns DA. The incidence of acute oxaliplatin-induced neuropathy and its impact on treatment in the first cycle: a systematic review. BMC Cancer. 2018 Apr 12;18(1):410.სრული ტექსტი  აბსტრაქტი

293. Lee S, Ma C, Shi Q, et al. Potential mediators of oxaliplatin-induced peripheral neuropathy from adjuvant therapy in stage III colon cancer: findings from CALGB (Alliance)/SWOG 80702. J Clin Oncol. 2023 Feb 10;41(5):1079-91.სრული ტექსტი  აბსტრაქტი

294. Stintzing S, Kapaun C, Laubender RP, et al. Prognostic value of cetuximab-related skin toxicity in metastatic colorectal cancer patients and its correlation with parameters of the epidermal growth factor receptor signal transduction pathway: results from a randomized trial of the GERMAN AIO CRC Study Group. Int J Cancer. 2012 Jun 26;132(1):236-45.სრული ტექსტი  აბსტრაქტი

295. Patel SV, Liberman SA, Burgess PL, et al. The American Society of Colon and Rectal Surgeons clinical practice guidelines for the reduction of venous thromboembolic disease in colorectal surgery. Dis Colon Rectum. 2023 Sep 1;66(9):1162-73.სრული ტექსტი

296. Emoto S, Nozawa H, Kawai K, et al. Venous thromboembolism in colorectal surgery: incidence, risk factors, and prophylaxis. Asian J Surg. 2019 Sep;42(9):863-73.სრული ტექსტი  აბსტრაქტი

297. Patel SV, Zhang L, Wei XS, et al. A population-based cohort study of venous thromboembolism rates following surgery and during adjuvant chemotherapy in patients with colon cancer. Dis Colon Rectum. 2020 Mar;63(3):336-45.სრული ტექსტი  აბსტრაქტი

298. National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: management of immunotherapy-related toxicities [internet publication].სრული ტექსტი

299. Hassan C, Antonelli G, Dumonceau JM, et al. Post-polypectomy colonoscopy surveillance: European Society of Gastrointestinal Endoscopy (ESGE) Guideline - Update 2020. Endoscopy. 2020 Aug;52(8):687-700.სრული ტექსტი  აბსტრაქტი

300. Ligibel JA, Bohlke K, May AM, et al. exercise, diet, and weight management during cancer treatment: ASCO Guideline. J Clin Oncol. 2022 Aug 1;40(22):2491-507.სრული ტექსტი  აბსტრაქტი

301. Veettil SK, Lim KG, Ching SM, et al. Effects of aspirin and non-aspirin nonsteroidal anti-inflammatory drugs on the incidence of recurrent colorectal adenomas: a systematic review with meta-analysis and trial sequential analysis of randomized clinical trials. BMC Cancer. 2017 Nov 14;17(1):763.სრული ტექსტი  აბსტრაქტი

302. Liao X, Lochhead P, Nishihara R, et al. Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival. N Engl J Med. 2012 Oct 25;367(17):1596-606.სრული ტექსტი  აბსტრაქტი

303. Dulai PS, Singh S, Marquez E, et al. Chemoprevention of colorectal cancer in individuals with previous colorectal neoplasia: systematic review and network meta-analysis. BMJ. 2016 Dec 5;355:i6188.სრული ტექსტი  აბსტრაქტი

304. Hua X, Phipps AI, Burnett-Hartman AN, et al. Timing of aspirin and other nonsteroidal anti-inflammatory drug use among patients with colorectal cancer in relation to tumor markers and survival. J Clin Oncol. 2017 Aug 20;35(24):2806-13. აბსტრაქტი

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