Dyshidrotic dermatitis

References

Key articles

Agner T, Elsner P. Hand eczema: epidemiology, prognosis and prevention. J Eur Acad Dermatol Venereol. 2020 Jan;34 Suppl 1:4-12.Full text  Abstract

Elsner P, Agner T. Hand eczema: treatment. J Eur Acad Dermatol Venereol. 2020 Jan;34 Suppl 1:13-21.Full text  Abstract

Jacob PT, Marie LAS, Jose HA, et al. Guidelines for diagnosis, prevention and treatment of hand eczema. Contact Dermatitis. 2022 May;86(5):357-78. Abstract

Christoffers WA, Coenraads PJ, Svensson Å, et al. Interventions for hand eczema. Cochrane Database Syst Rev. 2019 Apr 26;4(4):CD004055.Full text  Abstract

Reference articles

1. Agner T, Elsner P. Hand eczema: epidemiology, prognosis and prevention. J Eur Acad Dermatol Venereol. 2020 Jan;34 Suppl 1:4-12.Full text  Abstract

2. Fowler JF Jr, Storrs FJ. Nickel allergy and dyshidrotic eczema: are they related? Am J Contact Dermatol. 2001;12:119-121. Abstract

3. Agrup G. Hand eczema and other hand dermatoses in south Sweden. Acta Derm Venereol (Stockh). 1969;49(Suppl 61):5-91.

4. Magina S, Barros MA, Ferreira JA, et al. Atopy, nickel sensitivity, occupation, and clinical patterns in different types of hand dermatitis. Am J Contact Dermat. 2003;14:63-68. Abstract

5. Gladys TE, Maczuga S, Flamm A. Characterizing demographics and cost of care for dyshidrotic eczema. Contact Dermatitis. 2022 Feb;86(2):107-12.Full text  Abstract

6. Lodi A, Betti R, Chiarelli G, et al. Epidemiological, clinical and allergological observations on pompholyx. Contact Dermatitis. 1992;26:17-21. Abstract

7. Edman B. Palmar eczema: a pathogenic role for acetylsalicyclic acid, contraceptives and smoking? Acta Derm Venereol. 1988;68:402-407. Abstract

8. Lehucher-Michel MP, Koeppel MC, Lanteaume A, et al. Dyshidrotic eczema and occupation: a descriptive study. Contact Dermatitis. 2000;43:200-205. Abstract

9. Bryld LE, Agner T, Menne T. Relationship between vesicular eruptions on the hands and tinea pedis, atopic dermatitis and nickel allergy. Acta Derm Venereol. 2003;83:186-188. Abstract

10. Prystupa K, Rudzki E. Oral tolerance of nickel in patients with dyshidrosis. Contact Dermatitis. 2000;42:276-277. Abstract

11. Veien NK, Hattel T, Justesen O, et al. Oral challenge with metal salts. (I). Vesicular patch-test-negative hand eczema. Contact Dermatitis. 1983;9:402-406. Abstract

12. Crosti C, Lodi A. Pompholyx: A still unresolved kind of eczema. Dermatol. 1993;186:241-242. Abstract

13. Yokozeki H, Katayama I, Nishioka K, et al. The role of metal allergy and local hyperhidrosis in the pathogenesis of pompholyx. J Dermatol. 1992;19:964-967. Abstract

14. Wollina U, Abdel Naser MB. Pharmacotherapy of pompholyx. Expert Opin Pharmacother. 2004;5:1517-1522. Abstract

15. Elsner P, Agner T. Hand eczema: treatment. J Eur Acad Dermatol Venereol. 2020 Jan;34 Suppl 1:13-21.Full text  Abstract

16. Shenefelt PD. Psychodermatological disorders: recognition and treatment. Int J Dermatol. 2011;50:1309-22. Abstract

17. Kutzner H, Wurzel R, Wolff H. Are acrosyringia involved in the pathogenesis of "dyshidrosis"? Am J Dermatopathol. 1986;8:109-116. Abstract

18. de Boer EM, Bruynzeel DP, van Ketel WG. Dyshidrotic eczema as an occupational dermatitis in metal workers. Contact Dermatitis. 1988;19:184-188. Abstract

19. Thelin I, Agrup G. Pompholyx - a one year series. Acta Derm Venereol. 1985;65:214-217. Abstract

20. Guillet MH, Wierzbicka E, Guillet S, et al. A 3-year causative study of pompholyx in 120 patients. Arch Dermatol. 2007;143:1504-1508. Abstract

21. Vocks E, Plötz SG, Ring J. The Dyshidrotic Eczema and Severity Index - a score developed for the assessment of dyshidrotic eczema. Dermatol. 1999;198:265-269. Abstract

22. Jacob PT, Marie LAS, Jose HA, et al. Guidelines for diagnosis, prevention and treatment of hand eczema. Contact Dermatitis. 2022 May;86(5):357-78. Abstract

23. Warshaw E. Therapeutic options for chronic hand dermatitis. Dermatol Ther. 2004;17:240-250. Abstract

24. Swartling C, Naver H, Lindberg M, et al. Treatment of dyshidrotic hand dermatitis with intradermal botulinum toxin. J Am Acad Dermatol. 2002;47:667-671. Abstract

25. Odia S, Vocks E, Rakoski J, et al. Successful treatment of dyshidrotic hand eczema using tap water iontophoresis with pulsed direct current. Acta Derm Venereol. 1996;76:472-474. Abstract

26. Wollina U, Karamfilov T. Adjuvant botulinum toxin A in dyshidrotic hand eczema: a controlled prospective pilot study with left-right comparison. J Eur Acad Dermatol Venereol. 2002;16:40-42. Abstract

27. Veien NK, Kaaber K. Nickel, cobalt and chromium sensitivity in patients with pompholyx (dyshidrotic eczema). Contact Dermatitis. 1979;5:371-374. Abstract

28. Veien NK, Hattel T, Justesen O, et al. Dietary restrictions in the treatment of adult patients with eczema. Contact Dermatitis. 1987;17:223-228. Abstract

29. Veien NK, Hattel T, Justesen O, et al. Dietary treatment of nickel dermatitis. Acta Derm Venereol. 1985;65:138-142. Abstract

30. Kaaber K, Menné T, Veien N, et al. Treatment of nickel dermatitis with Antabuse; a double blind study. Contact Dermatitis. 1983;9:297-299. Abstract

31. Pigatto PD, Gibelli E, Fumagalli M, et al. Disodium cromoglycate versus diet in the treatment and prevention of nickel-positive pompholyx. Contact Dermatitis. 1990;22:27-31. Abstract

32. Santucci B, Cristaudo A, Cannistraci C, et al. Nickel sensitivity: effects of prolonged oral intake of the element. Contact Dermatitis. 1988;19:202-205. Abstract

33. Sharma AD. Low nickel diet in dermatology. Indian J Dermatol. 2013 May;58(3):240.Full text  Abstract

34. Veien NK, Olhom Larsen P, Thestrup-Pedersen K, et al. Long-term, intermittent treatment of chronic hand eczema with mometasone furoate. Br J Dermatol. 1999;140:882-886. Abstract

35. Volden G. Successful treatment of chronic skin diseases with clobetasol propionate and a hydrocolloid occlusive dressing. Acta Derm Venereol. 1992;72(1):69-71. Abstract

36. Sidbury R, Alikhan A, Bercovitch L, et al. Guidelines of care for the management of atopic dermatitis in adults with topical therapies. J Am Acad Dermatol. 2023 Jul;89(1):e1-20.Full text  Abstract

37. Schnopp C, Remling R, Möhrenschlager M, et al. Topical tacrolimus (FK 506) and mometasone furoate in the treatment of dyshidrotic palmar eczema: A randomized, observer-blinded trial. J Am Acad Dermatol. 2002;46:73-77. Abstract

38. Belsito DV, Fowler JF Jr, Marks JG Jr, et al. Pimecrolimus cream 1%: a potential new treatment for chronic hand dermatitis. Cutis. 2004;73:31-38. Abstract

39. Christoffers WA, Coenraads PJ, Svensson Å, et al. Interventions for hand eczema. Cochrane Database Syst Rev. 2019 Apr 26;4(4):CD004055.Full text  Abstract

40. Davis MD, McEvoy M, el-Azhary RA. Topical psoralen-ultraviolet A therapy for palmoplantar dermatoses: experience with 35 consecutive patients. Mayo Clin Proc. 1998;73:407-411. Abstract

41. Schempp CM, Müller H, Czech W, et al. Treatment of chronic palmoplantar eczema with local bath-PUVA therapy. J Am Acad Dermatol. 1997;36:733-737. Abstract

42. Behrens S, von Kobyletzki G, Gruss C, et al. PUVA-bath photochemotherapy (PUVA-soak therapy) of recalcitrant dermatoses of the palms and soles. Photodermatol Photoimmunol Photomed. 1999;15:47-51. Abstract

43. Egan CA, Rallis TM, Meadows KP, et al. Low-dose oral methotrexate treatment for recalcitrant palmoplantar pompholyx. J Am Acad Derm. 1999;40:612-614. Abstract

44. Scerri L. Azathioprine in dermatological practice. An overview with special emphasis on its use in non-bullous inflammatory dermatoses. Adv Exp Med Biol. 1999;455:343-348. Abstract

45. Granlund H, Erkko P, Eriksson E, et al. Comparison of cyclosporine and topical betamethasone-17, 21-dipropionate in the treatment of severe chronic hand eczema. Acta Derm Venereol. 1996;76:371-376. Abstract

46. Pickenäcker A, Luger TA, Schwartz T. Dyshidrotic eczema treated with mycophenolate mofetil. Arch Dermatol. 1998;134:378-379. Abstract

47. Lowe NJ, Weingarten D, Bourget T, et al. PUVA therapy for psoriasis: comparison of oral and bath-water delivery of 8-methoxypsoralen. J Am Acad Dermatol. 1986;14:754-60. Abstract

48. LeVine MJ, Parrish JA, Fitzpatrick TB. Oral methoxsalen photochemotherapy (PUVA) of dyshidrotic eczema. Acta Derm Venereol. 1981;61:570-71. Abstract

49. Polderman MC, Govaert JC, le Cessie S, et al. A double-blind placebo-controlled trial of UVA-1 in the treatment of dyshidrotic eczema. Clin Exp Dermatol. 2003;28:584-87. Abstract

50. Rivard J, Lim HW. The use of 308-nm excimer laser for dermatoses: experience with 34 patients. J Drugs Dermatol. 2006;5:550-54. Abstract

51. Wollina U. Pompholyx: what's new? Expert Opin Investig Drugs. 2008;17:897-904. Abstract

52. Simpson EL, Bieber T, Guttman-Yassky E, et al. Two phase 3 trials of Dupilumab versus placebo in atopic dermatitis. N Engl J Med. 2016 Dec 15;375(24):2335-48.Full text  Abstract

53. Ho JSS, Molin S. A review of existing and new treatments for the management of hand eczema. J Cutan Med Surg. 2023 Jul 27;:12034754231188325.Full text  Abstract

54. Voorberg AN, Romeijn GLE, de Bruin-Weller MS, et al. The long-term effect of dupilumab on chronic hand eczema in patients with moderate to severe atopic dermatitis-52 week results from the Dutch BioDay Registry. Contact Dermatitis. 2022 Aug;87(2):185-91.Full text  Abstract

55. Voorberg AN, Kamphuis E, Christoffers WA, et al. Efficacy and safety of dupilumab in patients with severe chronic hand eczema with inadequate response or intolerance to alitretinoin: a randomized, double-blind, placebo-controlled phase IIb proof-of-concept study. Br J Dermatol. 2023 Sep 15;189(4):400-9.Full text  Abstract

56. Oosterhaven JAF, Romeijn GLE, Schuttelaar MLA. Dupilumab treatment of very severe refractory atopic hand eczema. JAMA Dermatol. 2018 Aug 1;154(8):969-70.Full text  Abstract

57. Cheng J, Facheris P, Ungar B, et al. Current emerging and investigational drugs for the treatment of chronic hand eczema. Expert Opin Investig Drugs. 2022 Aug;31(8):843-53.Full text  Abstract

58. Deng L, Luo Y, An B, et al. Recalcitrant palmar-plantar atopic dermatitis successfully treated with dupilumab: a case series. Clin Cosmet Investig Dermatol. 2022;15:2421-26.Full text  Abstract

59. Bissonnette R, Papp KA, Poulin Y, et al. Topical tofacitinib for atopic dermatitis: a phase IIa randomized trial. Br J Dermatol. 2016 Nov;175(5):902-11.Full text  Abstract

60. Nakagawa H, Nemoto O, Igarashi A, et al. Delgocitinib ointment, a topical Janus kinase inhibitor, in adult patients with moderate to severe atopic dermatitis: a phase 3, randomized, double-blind, vehicle-controlled study and an open-label, long-term extension study. J Am Acad Dermatol. 2020 Apr;82(4):823-31.Full text  Abstract

61. Papp K, Szepietowski JC, Kircik L, et al. Efficacy and safety of ruxolitinib cream for the treatment of atopic dermatitis: results from 2 phase 3, randomized, double-blind studies. J Am Acad Dermatol. 2021 Oct;85(4):863-72.Full text  Abstract

62. Reich K, Thyssen JP, Blauvelt A, et al. Efficacy and safety of abrocitinib versus dupilumab in adults with moderate-to-severe atopic dermatitis: a randomised, double-blind, multicentre phase 3 trial. Lancet. 2022 Jul 23;400(10348):273-82.Full text  Abstract

63. Bieber T, Simpson EL, Silverberg JI, et al. Abrocitinib versus placebo or dupilumab for atopic dermatitis. N Engl J Med. 2021 Mar 25;384(12):1101-12.Full text  Abstract

64. Shi VY, Bhutani T, Fonacier L, et al. Phase 3 efficacy and safety of abrocitinib in adults with moderate-to-severe atopic dermatitis after switching from dupilumab (JADE EXTEND). J Am Acad Dermatol. 2022 Aug;87(2):351-58.Full text  Abstract

65. Simpson EL, Sinclair R, Forman S, et al. Efficacy and safety of abrocitinib in adults and adolescents with moderate-to-severe atopic dermatitis (JADE MONO-1): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial. Lancet. 2020 Jul 25;396(10246):255-66.Full text  Abstract

66. Silverberg JI, Simpson EL, Thyssen JP, et al. Efficacy and safety of abrocitinib in patients with moderate-to-severe atopic dermatitis: a randomized clinical trial. JAMA Dermatol. 2020 Aug 1;156(8):863-73.Full text  Abstract

67. Guttman-Yassky E, Silverberg JI, Nemoto O, et al. Baricitinib in adult patients with moderate-to-severe atopic dermatitis: a phase 2 parallel, double-blinded, randomized placebo-controlled multiple-dose study. J Am Acad Dermatol. 2019 Apr;80(4):913-21.e9.Full text  Abstract

68. Bieber T, Reich K, Paul C, et al. Efficacy and safety of baricitinib in combination with topical corticosteroids in patients with moderate-to-severe atopic dermatitis with inadequate response, intolerance or contraindication to ciclosporin: results from a randomized, placebo-controlled, phase III clinical trial (BREEZE-AD4). Br J Dermatol. 2022 Sep;187(3):338-52.Full text  Abstract

69. Guttman-Yassky E, Teixeira HD, Simpson EL, et al. Once-daily upadacitinib versus placebo in adolescents and adults with moderate-to-severe atopic dermatitis (Measure Up 1 and Measure Up 2): results from two replicate double-blind, randomised controlled phase 3 trials. Lancet. 2021 Jun 5;397(10290):2151-68.Full text  Abstract

70. Reich K, Teixeira HD, de Bruin-Weller M, et al. Safety and efficacy of upadacitinib in combination with topical corticosteroids in adolescents and adults with moderate-to-severe atopic dermatitis (AD Up): results from a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet. 2021 Jun 5;397(10290):2169-81.Full text  Abstract

71. Kiszla BM, Orlowski TJ, Kole LCS. Efficacy and tolerance of upadacitinib in the treatment of dyshidrotic eczema. JAAD Case Rep. 2023 Aug;38:141-43.Full text  Abstract

72. Paller AS, Tom WL, Lebwohl MG, et al. Efficacy and safety of crisaborole ointment, a novel, nonsteroidal phosphodiesterase 4 (PDE4) inhibitor for the topical treatment of atopic dermatitis (AD) in children and adults. J Am Acad Dermatol. 2016 Sep;75(3):494-503.e6.Full text  Abstract

73. Chu DK, Chu AWL, Rayner DG, et al. Topical treatments for atopic dermatitis (eczema): systematic review and network meta-analysis of randomized trials. J Allergy Clin Immunol. 2023 Sep 5.Full text  Abstract

74. Kahn JS, Grossman-Kranseler JS, Zancanaro P, et al. Topical crisaborole in the treatment of atopic hand dermatitis: a retrospective chart review. Dermatitis. 2021 Nov-Dec 01;32(6):e141-43.Full text  Abstract

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