Assessment of neutropenia

References

Key articles

Boxer LA, Newberger PE. A molecular classification of congenital neutropenia syndromes. Pediatr Blood Cancer. 2007 Oct 15;49(5):609-14.Full text  Abstract

Cham B, Bonilla MA, Winkelstein J. Neutropenia associated with primary immunodeficiency syndromes. Semin Hematol. 2002 Apr;39(2):107-12. Abstract

Taplitz RA, Kennedy EB, Bow EJ, et al. Outpatient management of fever and neutropenia in adults treated for malignancy: American Society of Clinical Oncology and Infectious Diseases Society of America clinical practice guideline update. J Clin Oncol. 2018 May 10;36(14):1443-53.Full text  Abstract

Reference articles

1. Dale DC, Welte K. Neutrophenia and neutrophilia. In: Kaushansky K, Prchal JT, Burns LJ, et al, eds. Williams hematology. 10th ed. New York, NY: McGraw-Hill; 2021Full text

2. Lichtman MA. Classification and clinical manifestations of neutrophil disorders. In: Kaushansky K, Prchal JT, Burns LJ, et al, eds. Williams hematology. 10th ed. New York, NY: McGraw-Hill; 2021.Full text

3. Newburger PE, Dale DC. Evaluation and management of patients with isolated neutropenia. Semin Hematol. 2013 Jul;50(3):198-206.Full text  Abstract

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12. Andres E, Maloisel F. Idiosyncratic drug-induced agranulocytosis or acute neutropenia. Curr Opin Hematol. 2008 Jan;15(1):15-21. Abstract

13. Boccia R, Glaspy J, Crawford J, et al. Chemotherapy-induced neutropenia and febrile neutropenia in the US: a beast of burden that needs to be tamed? Oncologist. 2022 Aug 5;27(8):625-36.Full text  Abstract

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17. Andersohn F, Konzen C, Garbe E. Systematic review: Agranulocytosis induced by nonchemotherapy drugs. Ann Intern Med. 2007 May 1;146(9):657-65. Abstract

18. Theophile H, Begaud B, Martin K., et al. Incidence of agranulocytosis in Southwest France. Eur J Epidemiol. 2004;19(6):563-5. Abstract

19. van der Klauw MM, Goudsmit R, Halie MR, et al. A population-based case-cohort study of drug-associated agranulocytosis. Arch Intern Med. 1999 Feb 22;159(4):369-74. Abstract

20. Andres E, Maloisel F, Kurtz JE, et al. Modern management of non-chemotherapy drug-induced agranulocytosis: a monocentric cohort study of 90 cases and review of the literature. Eur J Intern Med. 2002 Aug;13(5):324-8. Abstract

21. Salama A, Schutz B, Kiefel V, et al. Immune-mediated agranulocytosis related to drugs and their metabolites: mode of sensitization and heterogeneity of antibodies. Br J Haematol. 1989 Jun;72(2):127-32. Abstract

22. Murphy MF, Chapman JF, Metcalfe P, et al. Antibiotic-induced neutropenia. Lancet. 1985 Dec 7;2(8467):1306-7. Abstract

23. Bhatt V, Saleem A. Review: Drug-induced neutropenia - pathophysiology, clinical features, and management. Ann Clin Lab Sci. 2004 Spring;34(2):131-7.Full text  Abstract

24. Schwartzberg LS. Neutropenia: etiology and pathogenesis. Clin Cornerstone. 2006;8 (Suppl 5):S5-11. Abstract

25. Capsoni F, Sarzi-Puttini P, Zanella A. Primary and secondary autoimmune neutropenia. Arthritis Res Ther. 2005;7(5):208-14.Full text  Abstract

26. Klein C, Grudzien M, Appaswamy G, et al. HAX1 deficiency causes autosomal recessive severe congenital neutropenia (Kostmann disease). Nat Genet. 2007 Jan;39(1):86-92. Abstract

27. Bonilla MA, Dale D, Zeidler C, et al. Long-term safety of treatment with recombinant human granulocyte colony-stimulating factor (r-metHuG-CSF) in patients with severe congenital neutropenias. Br J Haematol. 1994 Dec;88(4):723-30. Abstract

28. Freedman MH. Safety of long-term administration of granulocyte colony-stimulating factor for severe chronic neutropenia. Curr Opin Hematol. 1997 May;4(3):217-24. Abstract

29. Welte K, Zeidler C, Dale DC. Severe congenital neutropenia. Semin Hematol. 2006 Jul;43(3):189-95. Abstract

30. Dror Y, Freedman MH. Shwachman-Diamond syndrome: An inherited preleukemic bone marrow failure disorder with aberrant hematopoietic progenitors and faulty marrow microenvironment. Blood. 1999 Nov 1;94(9):3048-54.Full text  Abstract

31. Boocock GR, Morrison JA, Popovic M, et al. Mutations in SBDS are associated with Shwachman-Diamond syndrome. Nat Genet. 2003 Jan;33(1):97-101. Abstract

32. Son JS, Seo GH, Kim YM, et al. Clinical and genetic features of four patients with pearson syndrome: an observational study. Medicine (Baltimore). 2022 Feb 4;101(5):e28793.Full text  Abstract

33. Boxer LA, Newberger PE. A molecular classification of congenital neutropenia syndromes. Pediatr Blood Cancer. 2007 Oct 15;49(5):609-14.Full text  Abstract

34. van Raam BJ, Kuijpers TW. Mitochondrial defects lie at the basis of neutropenia in Barth syndrome. Curr Opin Hematol. 2009 Jan;16(1):14-9. Abstract

35. Ancliff PJ. Congenital neutropenia. Blood Rev. 2003 Dec;17(4):209-16. Abstract

36. Aprikyan AA, Liles WC, Park JR, et al. Myelokathexis, a congenital disorder of severe neutropenia characterized by accelerated apoptosis and defective expression of bcl-x in neutrophil precursors. Blood. 2000 Jan 1;95(1):320-7.Full text  Abstract

37. Kivitie-Kallio S, Norio R. Cohen syndrome: essential features, natural history, and heterogeneity. Am J Med Genet. 2001 Aug 1;102(2):125-35. Abstract

38. Taban M, Memoracion-Peralta DS, Wang H, et al. Cohen syndrome: report of nine cases and review of the literature, with emphasis on ophthalmic features. J AAPOS. 2007 Oct;11(5):431-7. Abstract

39. Cham B, Bonilla MA, Winkelstein J. Neutropenia associated with primary immunodeficiency syndromes. Semin Hematol. 2002 Apr;39(2):107-12. Abstract

40. Gorlin RJ, Gelb B, Diaz GA, et al. WHIM syndrome, an autosomal dominant disorder: clinical, hematological, and molecular studies. Am J Med Genet. 2000 Apr 24;91(5):368-76. Abstract

41. Maaloul I, Talmoudi J, Chabchoub I, et al. Chediak-higashi syndrome presenting in accelerated phase: a case report and literature review. Hematol Oncol Stem Cell Ther. 2016 Jun;9(2):71-5.Full text  Abstract

42. Heinz WJ, Buchheidt D, Christopeit M, et al. Diagnosis and empirical treatment of fever of unknown origin (FUO) in adult neutropenic patients: guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO). Ann Hematol. 2017 Nov;96(11):1775-92.Full text  Abstract

43. Kochanek M, Schalk E, von Bergwelt-Baildon M, et al. Management of sepsis in neutropenic cancer patients: 2018 guidelines from the Infectious Diseases Working Party (AGIHO) and Intensive Care Working Party (iCHOP) of the German Society of Hematology and Medical Oncology (DGHO). Ann Hematol. 2019 May;98(5):1051-69. Abstract

44. Clarke RT, Jenyon T, van Hamel Parsons V, et al. Neutropenic sepsis: management and complications. Clin Med (Lond). 2013 Apr;13(2):185-7.Full text

45. Singer M, Deutschman CS, Seymour CW, et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 2016 Feb 23;315(8):801-10.Full text  Abstract

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50. Academy of Medical Royal Colleges. Statement on the initial antimicrobial treatment of sepsis. May 2022 [internet publication].Full text

51. Schlapbach LJ, Watson RS, Sorce LR, et al. International consensus criteria for pediatric sepsis and septic shock. JAMA. 2024 Feb 27;331(8):665-74.Full text  Abstract

52. Surviving Sepsis Campaign. Hour-1 bundle: initial resuscitation for sepsis and septic shock. 2019 [internet publication].Full text

53. James RM, Kinsey SE. The investigation and management of chronic neutropenia in children. Arch Dis Child. 2006 Oct;91(10):852-8.Full text  Abstract

54. Newburger PE. Disorders of neutrophil number and function. Hematology Am Soc Hematol Educ Program. 2006:104-10. Abstract

55. Zeidler C, Welte K. Kostmann syndrome and severe congenital neutropenia. Semin Hematol. 2002 Apr;39(2):82-8. Abstract

56. Taplitz RA, Kennedy EB, Bow EJ, et al. Outpatient management of fever and neutropenia in adults treated for malignancy: American Society of Clinical Oncology and Infectious Diseases Society of America clinical practice guideline update. J Clin Oncol. 2018 May 10;36(14):1443-53.Full text  Abstract

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