Vitamin C deficiency

Centers for Disease Control and Prevention. Nutrition and growth: refugee health domestic guidance. May 2024 [internet publication].Full text

Dietary Guidelines for Americans. 2020-2025 dietary guidelines for Americans. Dec 2020 [internet publication].Full text

Gonzalez-Campoy JM, St Jeor ST, Castorino K, et al. Clinical practice guidelines for healthy eating for the prevention and treatment of metabolic and endocrine diseases in adults: cosponsored by the American Association of Clinical Endocrinologists/the American College of Endocrinology and the Obesity Society. Endocr Pract. 2013 Sep-Oct;19 Suppl 3:1-82.Full text

Panel on Dietary Antioxidants and Related Compounds, Subcommittees on Upper Reference Levels of Nutrients and Interpretation and Uses of DRIs, Standing Committee on the Scientific Evaluation of Dietary Reference Intakes, Food and Nutrition Board, Institute of Medicine. Chapter 5: vitamin C. In: Food and Nutrition Board, Institute of Medicine’s Dietary reference intakes for vitamin C, vitamin E, selenium, and carotenoids. Washington DC: National Academy Press; 2000: 95-185.Full text  Abstract

National Institutes of Health. Vitamin C: fact sheet for health professionals. Mar 2021 [internet publication].Full text

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19. Hirschmann JV, Raugi GJ. Adult scurvy. J Am Acad Dermatol. 1999 Dec;41(6):895-906. Abstract

20. Levine M, Rumsey SC, Daruwala R, et al. Criteria and recommendations for vitamin C intake. JAMA. 1999 Apr 21;281(15):1415-23. Abstract

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23. Mertens MT, Gertner E. Rheumatic manifestations of scurvy: a report of three recent cases in a major urban center and a review. Semin Arthritis Rheum. 2011 Oct;41(2):286-90. Abstract

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25. Delanghe JR, Langlois MR, De Buyzere ML. Vitamin C deficiency and scurvy are not only a dietary problem but are codetermined by the haptoglobin polymorphism. Clin Chem. 2007 Aug;53(8):1397-400. Abstract

26. Siegel C, Barker B, Kunstadter M. Conditioned oral scurvy due to megavitamin C withdrawal. J Periodontol. 1982 Jul;53(7):453-5. Abstract

27. Clark JW. Conditioned oral scurvy due to megavitamin C withdrawal. J Periodontol. 1983 Mar;54(3):182-3. Abstract

28. Halver JE, Hardy RW. L-ascorbyl-2-sulfate alleviates Atlantic salmon scurvy. Proc Soc Exp Biol Med. 1994 Sep;206(4):421-4. Abstract

29. Committee on Animal Nutrition, Board on Agriculture, National Research Council (NRC) USA. Nutrient requirements of fish. Washington, DC: National Academy Press; 1993:31-2.

30. Roy RN, Guha BC. Production of experimental scurvy in a bird species. Nature. 1958 Dec 13;182(4650):1689-90. Abstract

31. Montel-Hagen A, Kinet S, Manel N, et al. Erythrocyte Glut1 triggers dehydroascorbic acid uptake in mammals unable to synthesize vitamin C. Cell. 2008 Mar 21;132(6):1039-48. Abstract

32. Kallner A, Hartmann D, Hornig D. Steady-state turnover and body pool of ascorbic acid in man. Am J Clin Nutr. 1979 Mar;32(3):530-9. Abstract

33. Linster CL, Van Schaftingen E. Vitamin C: biosynthesis, recycling and degradation in mammals. FEBS J. 2007 Jan;274(1):1-22.Full text  Abstract

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35. Kris-Etherton PM, Lichtenstein AH, Howard BV, et al. Antioxidant vitamin supplements and cardiovascular disease. Circulation. 2004 Aug 3;110(5):637-41.Full text  Abstract

36. Geber J, Murphy E. Scurvy in the Great Irish Famine: evidence of vitamin C deficiency from a mid-19th century skeletal population. Am J Phys Anthropol. 2012 Aug;148(4):512-24.Full text  Abstract

37. Farah Z, Rettenmaier R, Atkins D. Vitamin content of camel milk. Int J Vitam Nutr Res. 1992;62(1):30-3. Abstract

38. Deligny C, Dehlinger V, Goëb V, et al. Paradoxical appearance of adult scurvy in Martinique, French West Indies. Eur J Intern Med. 2011 Apr;22(2):e7-8. Abstract

39. Marik PE, Liggett A. Adding an orange to the banana bag: vitamin C deficiency is common in alcohol use disorders. Crit Care. 2019 May 10;23(1):165.Full text  Abstract

40. Mosdøl A, Erens B, Brunner EJ. Estimated prevalence and predictors of vitamin C deficiency within UK's low-income population. J Public Health (Oxf). 2008 Dec;30(4):456-60.Full text  Abstract

41. Ahmad SA, Al Thobiti TA, El Toum M, et al. Florid Scurvy in an Autistic Child on a Ketogenic Diet. Pediatr Emerg Care. 2018 Nov 19;:. Abstract

42. Willmott NS, Bryan RA. Case report: scurvy in an epileptic child on a ketogenic diet with oral complications. Eur Arch Paediatr Dent. 2008 Sep;9(3):148-52. Abstract

43. Cole JA, Warthan MM, Hirano SA, et al. Scurvy in a 10-year-old boy. Pediatr Dermatol. 2011 Jul-Aug;28(4):444-6. Abstract

44. Estienne M, Bugiani M, Bizzi A, et al. Scurvy hidden behind neuropsychiatric symptoms. Neurol Sci. 2011 Dec;32(6):1091-3. Abstract

45. Tengco LW, Rayco-Solon P, Solon JA, et al. Determinants of anemia among preschool children in the Philippines. J Am Coll Nutr. 2008 Apr;27(2):229-43. Abstract

46. Kamel AY, Dave NJ, Zhao VM, et al. Micronutrient Alterations During Continuous Renal Replacement Therapy in Critically Ill Adults: A Retrospective Study. Nutr Clin Pract. 2017 Dec 18;33(3):439-446. Abstract

47. Yepes-Calderón M, van der Veen Y, Martín Del Campo S F, et al. Vitamin C deficiency after kidney transplantation: a cohort and cross-sectional study of the TransplantLines biobank. Eur J Nutr. 2024 Sep;63(6):2357-66.Full text  Abstract

48. Riess KP, Farnen JP, Lambert PJ, et al. Ascorbic acid deficiency in bariatric surgical population. SSurg Obes Relat Dis. 2009 Jan-Feb;5(1):81-6. Abstract

49. Clements RH, Katasani VG, Palepu R, et al. Incidence of vitamin deficiency after laparoscopic Roux-en-Y gastric bypass in a university hospital setting. Am Surg. 2006 Dec;72(12):1196-202. Abstract

50. Fujii T, Luethi N, Young PJ, et al. Effect of vitamin C, hydrocortisone, and thiamine vs hydrocortisone alone on time alive and free of vasopressor support among patients with septic shock: the VITAMINS randomized clinical trial. JAMA. 2020 Feb 4;323(5):423-31.Full text  Abstract

51. Lamontagne F, Masse MH, Menard J, et al. Intravenous vitamin C in adults with sepsis in the intensive care unit. N Engl J Med. 2022 Jun 23;386(25):2387-98.Full text  Abstract

52. Gan R, Eintracht S, Hoffer LJ. Vitamin C deficiency in a university teaching hospital. J Am Coll Nutr. 2008 Jun;27(3):428-33. Abstract

53. Sharma Y, Miller M, Shahi R, et al. Vitamin C deficiency in Australian hospitalised patients: an observational study. Intern Med J. 2019 Feb;49(2):189-196. Abstract

54. Wu JR, Song EK, Moser DK, et al. Dietary Vitamin C Deficiency Is Associated With Health-Related Quality of Life and Cardiac Event-free Survival in Adults With Heart Failure. J Cardiovasc Nurs. 2019 Jan/Feb;34(1):29-35. Abstract

55. Song EK, Kang SM. Vitamin C Deficiency, High-Sensitivity C-Reactive Protein, and Cardiac Event-Free Survival in Patients With Heart Failure. J Cardiovasc Nurs. 2018 Jan/Feb;33(1):6-12. Abstract

56. Rasheed M, Simmons G, Fisher B, et al. Reduced plasma ascorbic acid levels in recipients of myeloablative conditioning and hematopoietic cell transplantation. Eur J Haematol. 2019 Aug 1;103(4):329-334. Abstract

57. Al-Subu AM, Long MT, Nelson KL, et al. Risk of hypovitaminosis and vitamin C deficiency in pediatric patients undergoing cardiopulmonary bypass. Pediatr Cardiol. 2023 Oct;44(7):1487-94. Abstract

58. Dunleavy KA, Ungaro RC, Manning L, et al. Vitamin C deficiency in inflammatory bowel disease: the forgotten micronutrient. Crohns Colitis 360. 2021 Feb 23;3(1):otab009.Full text  Abstract

59. Kletzel M, Powers K, Hayes M. Scurvy: a new problem for patients with chronic GVHD involving mucous membranes; an easy problem to resolve. Pediatr Transplant. 2014 Aug;18(5):524-6. Abstract

60. Perkins A, Sontheimer C, Otjen JP, et al. Scurvy Masquerading as Juvenile Idiopathic Arthritis or Vasculitis with Elevated Inflammatory Markers: A Case Series. J Pediatr. 2019 Dec 13;:.Full text  Abstract

61. Hood J, Hodges RE. Ocular lesions in scurvy. Am J Clin Nutr. 1969 May;22(5):559-67. Abstract

62. Berger MM, Shenkin A, Schweinlin A, et al. ESPEN micronutrient guideline. Clin Nutr. 2022 Jun;41(6):1357-424.Full text  Abstract

63. Pan T, Hennrikus EF, Hennrikus WL. Modern day scurvy in pediatric orthopaedics: a forgotten illness. J Pediatr Orthop. 2021 Mar 1;41(3):e279-84. Abstract

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67. Gulko E, Collins LK, Murphy RC, et al. MRI findings in pediatric patients with scurvy. Skeletal Radiol. 2015 Feb;44(2):291-7. Abstract

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70. Centers for Disease Control and Prevention. Nutrition and growth: refugee health domestic guidance. May 2024 [internet publication].Full text

71. Strametz R, Weberschock T, Erler A, et al. Critical view: parenteral administration of vitamins in asymptomatic patients. Z Allgemeinmed. 2008;84:502-6.

72. Fowler AA 3rd, Truwit JD, Hite RD, et al. Effect of vitamin C infusion on organ failure and biomarkers of inflammation and vascular injury in patients with sepsis and severe acute respiratory failure: the CITRIS-ALI randomized clinical trial. JAMA. 2019 Oct 1;322(13):1261-70.Full text  Abstract

73. Dietary Guidelines for Americans. 2020-2025 dietary guidelines for Americans. Dec 2020 [internet publication].Full text

74. Gonzalez-Campoy JM, St Jeor ST, Castorino K, et al. Clinical practice guidelines for healthy eating for the prevention and treatment of metabolic and endocrine diseases in adults: cosponsored by the American Association of Clinical Endocrinologists/the American College of Endocrinology and the Obesity Society. Endocr Pract. 2013 Sep-Oct;19 Suppl 3:1-82.Full text

75. Panel on Dietary Antioxidants and Related Compounds, Subcommittees on Upper Reference Levels of Nutrients and Interpretation and Uses of DRIs, Standing Committee on the Scientific Evaluation of Dietary Reference Intakes, Food and Nutrition Board, Institute of Medicine. Chapter 5: vitamin C. In: Food and Nutrition Board, Institute of Medicine’s Dietary reference intakes for vitamin C, vitamin E, selenium, and carotenoids. Washington DC: National Academy Press; 2000: 95-185.Full text  Abstract

76. Dionne CE, Laurin D, Desrosiers T, et al. Serum vitamin C and spinal pain: a nationwide study. Pain. 2016 Nov;157(11):2527-35. Abstract

77. National Institutes of Health. Vitamin C: fact sheet for health professionals. Mar 2021 [internet publication].Full text