Any patient with suspected or confirmed HPAI H5N1 virus infection should be started on antiviral treatment as soon as possible and isolated following recommended infection control precautions. Local and national public health authorities should be contacted immediately. Instructions for discharge or home care and risk management of clinically mild illness with HPAI H5N1 virus infection should be provided by local or national public health departments to fit the needs of the particular case. The health department will determine whether quarantine of exposed people, other forms of social distancing, and other pharmacologic and nonpharmacologic measures must be undertaken to prevent HPAI H5N1 virus transmission among exposed people in the community. Physicians are not recommended to manage HPAI H5N1 cases without close guidance and involvement by local or national public health departments.
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