Summary
Definition
History and exam
Key diagnostic factors
- use of nonpressure-relieving support surface
- localized skin changes on areas subjected to pressure
- shallow open wound or tissue loss on areas subjected to pressure
- a full-thickness wound on areas subjected to pressure with or without undermining (tunneling)
- a full-thickness wound with involvement of major tissues on areas subjected to pressure with or without undermining (tunneling)
- localized tenderness and warmth around area of wound
- increased exudate and/or foul odor
Risk factors
- immobility
- sensory impairment
- older age
- surgery
- intensive care stay
- malnourishment
- history of previous pressure ulcers
- environmental factors
- fecal or urinary incontinence
- diabetes mellitus
- peripheral vascular disease
Diagnostic tests
1st tests to order
- clinical diagnosis
Tests to consider
- erythrocyte sedimentation rate (ESR)
- WBC
- serum glucose or HbA1c
- deep tissue biopsy
- bone biopsy
- magnetic resonance imaging (MRI)
- duplex ultrasound
Emerging tests
- subepidermal moisture (SEM) measurement
Treatment algorithm
all patients
Contributors
Authors
Lisa J. Gould, MD, PhD
Staff Plastic Surgeon
South Shore Health Center for Wound Healing
Weymouth, MA
Clinical Associate Professor
Department of Medicine, Brown University Warren Alpert Medical School
Providence, RI
Disclosures
LG is a paid consultant for Solventum Medical, distributor of the vacuum-assisted closure (VAC) negative pressure wound therapy device and AVITA Medical. LG is a member of the National Pressure Injury Advisory Panel's Public Policy Committee, the American College of Surgeons Patient Education Committee, and the Real-World Evidence Work Group, Wound Care Collaborative Community. LG serves as a General Committee member for the International Wound Infection Institute. LG served as the vice chair of the Wound Care Collaborative Community (ended 2024) and was on the Board of Directors of the Wound Healing Society (ended 2026). She was the lead author for the Wound Healing Society 2023 Pressure Ulcer Guidelines update.
Acknowledgements
Dr Lisa J. Gould would like to gratefully acknowledge Dr Dan R. Berlowitz, Dr Madhuri Reddy, and Dr Stephen Thomas, previous contributors to this topic.
Disclosures
DRB and MR are the authors of a number of references cited in this topic. ST declares that he has no competing interests.
Peer reviewers
Jane Deng, MD
Assistant Professor of Medicine
David Geffen School of Medicine at UCLA
Los Angeles, CA
Disclosures
JD declares that she has no competing interests.
Keith Harding, FRCGP, FRCP, FRCS
Sub Dean of Innovation & Engagement
Head of Section of Wound Healing
School of Medicine
Cardiff University
Cardiff
UK
Disclosures
KH has worked in the area of wound healing for many years and has helped establish and sustain a section of wound healing in a university medical school. The school is entirely self-funded and receives funding from a wide range of commercial concerns in addition to the NHS and grant-giving bodies. The funding is provided to the University rather than to KH personally, and this funding is used to provide sustainability for a wide range of individuals employed within this section.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
References
Key articles
Edsberg LE, Black JM, Goldberg M, et al. Revised National Pressure Ulcer Advisory Panel pressure injury staging system: Revised pressure injury staging system. J Wound Ostomy Continence Nurs. 2016 Nov/Dec;43(6):585-97.Full text Abstract
Gould LJ, Alderden J, Aslam R, et al. WHS guidelines for the treatment of pressure ulcers - 2023 update. Wound Repair Regen. 2024 Jan-Feb;32(1):6-33.Full text Abstract
National Institute for Health and Care Excellence. Pressure ulcers: prevention and management of pressure ulcers. April 2014 [internet publication].Full text
Reference articles
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
Differentials
- Moisture-associated dermatitis
- Venous ulcers
- Arterial ulcers
More DifferentialsGuidelines
- Best practice recommendations for skin health and wound management: Chapter 7, prevention and management of pressure injuries
- Wound Healing Society 2023 update on guidelines for pressure ulcers
More GuidelinesPatient information
Pressure sores
More Patient informationCalculators
Norton Scale to Stratify Risk of Pressure Sores
More CalculatorsLog in or subscribe to access all of BMJ Best Practice
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