Postural orthostatic tachycardia syndrome

Vernino S, Bourne KM, Stiles LE, et al. Postural orthostatic tachycardia syndrome (POTS): state of the science and clinical care from a 2019 National Institutes of Health expert consensus meeting - part 1. Auton Neurosci. 2021 Nov;235:102828.Full text  Abstract

Sheldon RS, Grubb BP 2nd, Olshansky B, et al. 2015 Heart Rhythm Society expert consensus statement on the diagnosis and treatment of postural tachycardia syndrome, inappropriate sinus tachycardia, and vasovagal syncope. Heart Rhythm. 2015 Jun;12(6):e41-63.Full text  Abstract

Shen WK, Sheldon RS, Benditt DG, et al. 2017 ACC/AHA/HRS guideline for the evaluation and management of patients with syncope: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. Circulation. 2017 Aug 1;136(5):e25-e59.Full text  Abstract

Raj SR, Guzman JC, Harvey P, et al. Canadian Cardiovascular Society position statement on postural orthostatic tachycardia syndrome (POTS) and related disorders of chronic orthostatic intolerance. Can J Cardiol. 2020 Mar;36(3):357-72.Full text  Abstract

1. Vernino S, Bourne KM, Stiles LE, et al. Postural orthostatic tachycardia syndrome (POTS): state of the science and clinical care from a 2019 National Institutes of Health expert consensus meeting - part 1. Auton Neurosci. 2021 Nov;235:102828.Full text  Abstract

2. Sheldon RS, Grubb BP 2nd, Olshansky B, et al. 2015 Heart Rhythm Society expert consensus statement on the diagnosis and treatment of postural tachycardia syndrome, inappropriate sinus tachycardia, and vasovagal syncope. Heart Rhythm. 2015 Jun;12(6):e41-63.Full text  Abstract

3. Shen WK, Sheldon RS, Benditt DG, et al. 2017 ACC/AHA/HRS guideline for the evaluation and management of patients with syncope: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. Circulation. 2017 Aug 1;136(5):e25-e59.Full text  Abstract

4. Raj SR, Guzman JC, Harvey P, et al. Canadian Cardiovascular Society position statement on postural orthostatic tachycardia syndrome (POTS) and related disorders of chronic orthostatic intolerance. Can J Cardiol. 2020 Mar;36(3):357-72.Full text  Abstract

5. Fu Q, Vangundy TB, Galbreath MM, et al. Cardiac origins of the postural orthostatic tachycardia syndrome. J Am Coll Cardiol. 2010 Jun 22;55(25):2858-68.Full text  Abstract

6. Raj SR, Biaggioni I, Yamhure PC, et al. Renin-aldosterone paradox and perturbed blood volume regulation underlying postural tachycardia syndrome. Circulation. 2005 Apr 5;111(13):1574-82.Full text  Abstract

7. Jacob G, Biaggioni I, Mosqueda-Garcia R, et al. Relation of blood volume and blood pressure in orthostatic intolerance. Am J Med Sci. 1998 Feb;315(2):95-100. Abstract

8. Arnold AC, Ng J, Raj SR. Postural tachycardia syndrome - diagnosis, physiology, and prognosis. Auton Neurosci. 2018 Dec;215:3-11.Full text  Abstract

9. Freeman R, Wieling W, Axelrod FB, et al. Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome. Clin Auton Res. 2011 Apr;21(2):69-72. Abstract

10. Thieben MJ, Sandroni P, Sletten DM, et al. Postural orthostatic tachycardia syndrome: the Mayo clinic experience. Mayo Clin Proc. 2007 Mar;82(3):308-13. Abstract

11. Boris JR, Bernadzikowski T. Demographics of a large paediatric postural orthostatic tachycardia syndrome program. Cardiol Young. 2018 May;28(5):668-74. Abstract

12. Sandroni P, Opfer-Gehrking TL, McPhee BR, et al. Postural tachycardia syndrome: clinical features and follow-up study. Mayo Clin Proc. 1999 Nov;74(11):1106-10. Abstract

13. Shaw BH, Stiles LE, Bourne K, et al. The face of postural tachycardia syndrome - insights from a large cross-sectional online community-based survey. J Intern Med. 2019 Oct;286(4):438-48.Full text  Abstract

14. Watari M, Nakane S, Mukaino A, et al. Autoimmune postural orthostatic tachycardia syndrome. Ann Clin Transl Neurol. 2018 Apr;5(4):486-92.Full text  Abstract

15. Low PA, Sandroni P, Joyner M, et al. Postural tachycardia syndrome (POTS). J Cardiovasc Electrophysiol. 2009 Mar;20(3):352-8.Full text  Abstract

16. Low PA, Opfer-Gehrking TL, Textor SC, et al. Postural tachycardia syndrome (POTS). Neurology. 1995 Apr;45(4 suppl 5):S19-25. Abstract

17. Mathias CJ, Low DA, Iodice V, et al. Postural tachycardia syndrome - current experience and concepts. Nat Rev Neurol. 2011 Dec 6;8(1):22-34. Abstract

18. Ruzieh M, Grubb BP. Overview of the management of postural tachycardia syndrome in pregnant patients. Auton Neurosci. 2018 Dec;215:102-5.Full text  Abstract

19. Garland EM, Winker R, Williams SM, et al. Endothelial NO synthase polymorphisms and postural tachycardia syndrome. Hypertension. 2005 Nov;46(5):1103-10.Full text  Abstract

20. Jacob G, Garland EM, Costa F, et al. Beta2-adrenoceptor genotype and function affect hemodynamic profile heterogeneity in postural tachycardia syndrome. Hypertension. 2006 Mar;47(3):421-7.Full text  Abstract

21. Penny HA, Aziz I, Ferrar M, et al. Is there a relationship between gluten sensitivity and postural tachycardia syndrome? Eur J Gastroenterol Hepatol. 2016 Dec;28(12):1383-7. Abstract

22. Blitshteyn S. Autoimmune markers and autoimmune disorders in patients with postural tachycardia syndrome (POTS). Lupus. 2015 Nov;24(13):1364-9. Abstract

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25. Fedorowski A, Li H, Yu X, et al. Antiadrenergic autoimmunity in postural tachycardia syndrome. Europace. 2017 Jul 1;19(7):1211-9.Full text  Abstract

26. Li H, Yu X, Liles C, et al. Autoimmune basis for postural tachycardia syndrome. J Am Heart Assoc. 2014 Feb 26;3(1):e000755.Full text  Abstract

27. Vernino S, Stiles LE. Autoimmunity in postural orthostatic tachycardia syndrome: current understanding. Auton Neurosci. 2018 Dec;215:78-82.Full text  Abstract

28. Li H, Zhang G, Zhou L, et al. Adrenergic autoantibody-induced postural tachycardia syndrome in rabbits. J Am Heart Assoc. 2019 Oct;8(19):e013006.Full text  Abstract

29. Li J, Liao Y, Du J, et al. [Relationship between 24-hour urinary sodium and renin-angiotensin-aldosterone system in children with postural tachycardia syndrome]. [in chi]. Zhonghua Yi Xue Za Zhi. 2015 Sep 22;95(36):2928-32. Abstract

30. Mustafa HI, Garland EM, Biaggioni I, et al. Abnormalities of angiotensin regulation in postural tachycardia syndrome. Heart Rhythm. 2011 Mar;8(3):422-8. Abstract

31. Stewart JM, Medow MS, Glover JL, et al. Persistent splanchnic hyperemia during upright tilt in postural tachycardia syndrome. Am J Physiol Heart Circ Physiol. 2006 Feb;290(2):H665-73.Full text  Abstract

32. Reilly CC, Floyd SV, Lee K, et al. Breathlessness and dysfunctional breathing in patients with postural orthostatic tachycardia syndrome (POTS): The impact of a physiotherapy intervention. Auton Neurosci. 2020 Jan;223:102601.Full text  Abstract

33. Deb A, Morgenshtern K, Culbertson CJ, et al. A survey-based analysis of symptoms in patients with postural orthostatic tachycardia syndrome. Proc (Bayl Univ Med Cent). 2015 Apr;28(2):157-9.Full text  Abstract

34. Nayagam JS. Managing gastrointestinal manifestations in patients with PoTS: a UK DGH experience. Br J Cardiol. July 2019;26:101-4.Full text

35. Faure Walker N, Gall R, Gall N, et al. The postural tachycardia syndrome (PoTS) bladder-urodynamic findings. Urology. 2021 Jul;153:107-12. Abstract

36. Kaufman MR, Chang-Kit L, Raj SR, et al. Overactive bladder and autonomic dysfunction: lower urinary tract symptoms in females with postural tachycardia syndrome. Neurourol Urodyn. 2017 Mar;36(3):610-3.Full text  Abstract

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38. Lewis I, Pairman J, Spickett G, et al. Clinical characteristics of a novel subgroup of chronic fatigue syndrome patients with postural orthostatic tachycardia syndrome. J Intern Med. 2013 May;273(5):501-10.Full text  Abstract

39. Miller AJ, Stiles LE, Sheehan T, et al. Prevalence of hypermobile Ehlers-Danlos syndrome in postural orthostatic tachycardia syndrome. Auton Neurosci. 2020 Mar;224:102637. Abstract

40. Roma M, Marden CL, De Wandele I, et al. Postural tachycardia syndrome and other forms of orthostatic intolerance in Ehlers-Danlos syndrome. Auton Neurosci. 2018 Dec;215:89-96.Full text  Abstract

41. Kanjwal K, Karabin B, Kanjwal Y, et al. Autonomic dysfunction presenting as postural orthostatic tachycardia syndrome in patients with multiple sclerosis. Int J Med Sci. 2010 Mar 11;7(2):62-7.Full text  Abstract

42. Goodman BP. Evaluation of postural tachycardia syndrome (POTS). Auton Neurosci. 2018 Dec;215:12-9.Full text  Abstract

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52. Brignole M, Moya A, de Lange FJ, et al. 2018 ESC Guidelines for the diagnosis and management of syncope. Eur Heart J. 2018 Jun 1;39(21):1883-948.Full text  Abstract

53. Morgan K, Smith A, Blitshteyn S. POTS and pregnancy: a review of literature and recommendations for evaluation and treatment. Int J Womens Health. 2022 Dec 24;14:1831-47.Full text  Abstract

54. Gee ME, Watkins AK, Brown JN, et al. Ivabradine for the treatment of postural orthostatic tachycardia syndrome: a systematic review. Am J Cardiovasc Drugs. 2018 Jun;18(3):195-204. Abstract

55. Sutton R, Salukhe TV, Franzen-McManus AC, et al. Ivabradine in treatment of sinus tachycardia mediated vasovagal syncope. Europace. 2014 Feb;16(2):284-8.Full text  Abstract

56. Lai CC, Fischer PR, Brands CK, et al. Outcomes in adolescents with postural orthostatic tachycardia syndrome treated with midodrine and beta-blockers. Pacing Clin Electrophysiol. 2009 Feb;32(2):234-8. Abstract

57. Zhang F, Li X, Ochs T, et al. Midregional pro-adrenomedullin as a predictor for therapeutic response to midodrine hydrochloride in children with postural orthostatic tachycardia syndrome. J Am Coll Cardiol. 2012 Jul 24;60(4):315-20.Full text  Abstract

58. Ross AJ, Ocon AJ, Medow MS, et al. A double-blind placebo-controlled cross-over study of the vascular effects of midodrine in neuropathic compared with hyperadrenergic postural tachycardia syndrome. Clin Sci (Lond). 2014 Feb;126(4):289-96. Abstract

59. Garland EM, Gamboa A, Nwazue VC, et al. Effect of high dietary sodium intake in patients with postural tachycardia syndrome. J Am Coll Cardiol. 2021 May 4;77(17):2174-84.Full text  Abstract

60. Bourne KM, Sheldon RS, Hall J, et al. Compression garment reduces orthostatic tachycardia and symptoms in patients with postural orthostatic tachycardia syndrome. J Am Coll Cardiol. 2021 Jan 26;77(3):285-96.Full text  Abstract

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62. Smith EC, Diedrich A, Raj SR, et al. Splanchnic venous compression enhances the effects of ß-blockade in the treatment of postural tachycardia syndrome. J Am Heart Assoc. 2020 Jul 21;9(14):e016196.Full text  Abstract

63. Grubb AF, Grubb BP. Postural orthostatic tachycardia syndrome: new concepts in pathophysiology and management. Trends Cardiovasc Med. 2023 Feb;33(2):65-9. Abstract

64. Sheldon R, Raj SR, Rose MS, et al. Fludrocortisone for the prevention of vasovagal syncope: a randomized, placebo-controlled trial. J Am Coll Cardiol. 2016 Jul 5;68(1):1-9.Full text  Abstract

65. Gachoka D, Kanjwal K, Karabin B, et al. Desmopressin in the treatment of postural orthostatic tachycardia. J Innov Card Rhythm Manag. 2015 Dec;6(12):2222-6.Full text

66. Coffin ST, Black BK, Biaggioni I, et al. Desmopressin acutely decreases tachycardia and improves symptoms in the postural tachycardia syndrome. Heart Rhythm. 2012 Sep;9(9):1484-90. Abstract

67. Grubb BP. Postural tachycardia syndrome. Circulation. 2008 May 27;117(21):2814-7.Full text  Abstract

68. Moon J, Kim DY, Lee WJ, et al. Efficacy of propranolol, bisoprolol, and pyridostigmine for postural tachycardia syndrome: a randomized clinical trial. Neurotherapeutics. 2018 Jul;15(3):785-95.Full text  Abstract

69. Taub PR, Zadourian A, Lo HC, et al. Randomized trial of ivabradine in patients with hyperadrenergic postural orthostatic tachycardia syndrome. J Am Coll Cardiol. 2021 Feb 23;77(7):861-71.Full text  Abstract

70. Raj SR, Black BK, Biaggioni I, et al. Acetylcholinesterase inhibition improves tachycardia in postural tachycardia syndrome. Circulation. 2005 May 31;111(21):2734-40.Full text  Abstract

71. Kanjwal K, Karabin B, Sheikh M, et al. Pyridostigmine in the treatment of postural orthostatic tachycardia: a single-center experience. Pacing Clin Electrophysiol. 2011 Jun;34(6):750-5. Abstract

72. Vyas R, Nesheiwat Z, Ruzieh M, et al. Bupropion in the treatment of postural orthostatic tachycardia syndrome (POTS): a single-center experience. J Investig Med. 2020 Aug;68(6):1156-8. Abstract

73. Kanjwal K, Saeed B, Karabin B, et al. Erythropoietin in the treatment of postural orthostatic tachycardia syndrome. Am J Ther. 2012 Mar;19(2):92-5. Abstract

74. Miller AJ, Raj SR. Pharmacotherapy for postural tachycardia syndrome. Auton Neurosci. 2018 Dec;215:28-36.Full text  Abstract

75. Hoeldtke RD, Bryner KD, Hoeldtke ME, et al. Treatment of postural tachycardia syndrome: a comparison of octreotide and midodrine. Clin Auton Res. 2006 Dec;16(6):390-5. Abstract

76. Ruzieh M, Dasa O, Pacenta A, et al. Droxidopa in the treatment of postural orthostatic tachycardia syndrome. Am J Ther. 2017 Mar/Apr;24(2):e157-e161.Full text  Abstract

77. Ruzieh M, Baugh A, Dasa O, et al. Effects of intermittent intravenous saline infusions in patients with medication-refractory postural tachycardia syndrome. J Interv Card Electrophysiol. 2017 Apr;48(3):255-60. Abstract

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79. Goodman BP. Treatment updates in postural tachycardia syndrome. Curr Treat Options Neurol. 2020 Aug 25;22:35.Full text

80. ClinicalTrials.gov. IVIG (Gamunex-C) treatment study for POTS subjects (iSTAND). Jan 2023 [internet publication].Full text