Septic arthritis

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Last reviewed: 18 Jan 2026
Last updated: 22 Nov 2022

Summary

Definição

História e exame físico

Principais fatores diagnósticos

  • hot, swollen, painful, restricted joint
  • acute presentation
Detalhes completos

Outros fatores diagnósticos

  • fever
  • large joint
  • single joint
  • prosthetic joint
  • proportionality of symptoms
  • sexual activity
  • erythema migrans
  • risk factors
Detalhes completos

Fatores de risco

  • underlying joint disease
  • prosthetic joint
  • age
  • immunosuppression
  • contiguous spread
  • exposure to ticks
  • previous intra-articular corticosteroid injection
  • recent joint surgery
  • low socioeconomic status
Detalhes completos

Investigações diagnósticas

Primeiras investigações a serem solicitadas

  • synovial fluid microscopy, Gram stain, and polarising microscopy
  • synovial fluid culture and sensitivities
  • synovial fluid white cell count
  • blood culture and sensitivities
  • white cell count
  • erythrocyte sedimentation rate (ESR)
  • CRP
  • urea and electrolytes
  • LFTs
  • plain x-ray
  • ultrasound
Detalhes completos

Investigações a serem consideradas

  • procalcitonin (PCT)
  • MRI
  • synovial fluid polymerase chain reaction (PCR)
  • swabs for microscopy, culture, and sensitivity
  • urine dipstick, microscopy, culture, and sensitivity
  • enzyme-linked immunosorbent assay (ELISA)
  • synovial biopsy
Detalhes completos

Novos exames

  • calprotectin
Detalhes completos

Algoritmo de tratamento

Inicial

suspected infection in any joint(s): systemic involvement

suspected infection in prosthetic joint(s): no systemic involvement

suspected infection in native joint(s): no systemic involvement

AGUDA

confirmed infection in any joint(s): systemic involvement

confirmed infection in prosthetic joint(s): no systemic involvement

confirmed infection in native joint(s): no systemic involvement

unconfirmed infection with clinically suspected infection in native joint(s): no systemic involvement

Colaboradores

Consultores especialistas

Alexander Alexiou, MB, BS, BSc, DCH, FRCEM, DipIMC RSEd

Consultant in Emergency Medicine

Royal London Hospital

Consultant in Physician Response Unit

Barts Health NHS Trust/London Air Ambulance

London

UK

Declarações

AA declares that he has no competing interests.

Agradecimentos

BMJ Best Practice would like to gratefully acknowledge the previous expert contributors to this, whose work is retained in parts of the content:

Gerald Coakley PhD, FRCP

Consultant Rheumatologist

Queen Elizabeth Hospital

London

UK

GC is an author of a reference cited in this topic.

Catherine J. Mathews MSc, FRCP

Consultant Rheumatologist

Queen Elizabeth Hospital

London

UK

CJM is an author of a reference cited in this topic.

Johann Grundlingh

Emergency Medicine Consultant

Royal London Hospital

Barts Health NHS Trust

Honorary senior lecturer

Queen Mary University

London

UK

JG declares that he has no competing interests.

Theodore Young

CT1 anaesthetics

Anaesthetic Department

Peterborough City Hospital

Peterborough

UK

TY declares that he has no competing interests.

同行评议者

Catherine J. Mathews, MSc, FRCP

Consultant Rheumatologist

Lewisham and Greenwich NHS Trust

London

UK

利益声明

CJM is an author of references cited in this topic.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

参考文献

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

关键文献

Coakley G, Mathews C, Field M, et al. BSR and BHPR, BOA, RCGP and BSAC guidelines for management of the hot swollen joint in adults. Rheumatology (Oxford). 2006 Aug;45(8):1039-41.全文  摘要

Mathews CJ, Coakley G; British Society for Rheumatology. Hot joint update 2017. March 2017 [internet publication].全文

参考文献

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
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