Evidence tables

This table is a summary of the analysis reported in a guideline (underpinned by a systematic review) that focuses on the above important clinical question.

Confidence in the evidence is very low or low where GRADE has been performed and there is a trade off between benefits and harms of the intervention.

Population: Adults with type 2 diabetes

Intervention: Self-monitoring blood glucose

Comparison: No self-monitoring blood glucose (including usual care and self-monitoring of urine glucose)

OutcomeEffectiveness (BMJ rating)?Confidence in evidence (GRADE)?

Hemoglobin A1c (HbA1c) (follow up: 24-52 weeks)

Favors intervention


Fasting blood glucose (mmol/L) (follow up: 26-52 weeks)

Favors intervention


Postprandial blood glucose (mg/dL) at 26 weeks for adults with type 2 diabetes on diet, antidiabetic, and/or insulin medicines (follow up: 6 months)

Favors intervention


Any hypoglycemia from 26-52 weeks (follow up: 6-12 months)

Favors comparison


Severe hypoglycemia from 26-52 weeks (follow up: 6-12 months)

No statistically significant difference


Adverse events at 6 months for adults with type 2 diabetes on oral antidiabetes medicines (follow up: 6 months)

No statistically significant difference


Recommendations as stated in the source guideline

The guideline development group states: do not routinely offer self-monitoring of blood glucose levels for adults with type 2 diabetes unless:

  • the person is on insulin or

  • there is evidence of hypoglycemic episodes or

  • the person is on oral medication that may increase their risk of hypoglycemia while driving or operating machinery or

  • the person is pregnant, or is planning to become pregnant.


The guideline development group noted that self-monitoring of blood glucose provides the potential for tight glycemic control which reduces the risk of diabetes-related complications. However, the impact on hypoglycemic events is important in determining the safety and acceptability in patients.

This evidence table is related to the following section/s:

Cochrane Clinical Answers

Use of this content is subject to our disclaimer