Summary
Definition
History and exam
Key diagnostic factors
- left lower quadrant abdominal pain
- leukocytosis
- fever
- rectal bleeding
Other diagnostic factors
- guarding in left lower quadrant
- tenderness in left lower quadrant
- bloating
- constipation
- pelvic tenderness on digital rectal exam
- diffuse abdominal tenderness
- diarrhea
- palpable abdominal mass
Risk factors
- low dietary fiber
- diet rich in salt, meat, and sugar
- age >50 years
- obesity (BMI >30)
- nonsteroidal anti-inflammatory drug (NSAID) use
Diagnostic tests
1st tests to order
- CBC with differential
- CRP
Tests to consider
- CT scan of abdomen
- blood culture
- abdominal x-ray
- abdominal ultrasound (graded-compression)
- abdominal MRI scan
- chest x-ray
- contrast enema
- colonoscopy
- sigmoidoscopy
- angiogram
- diagnostic laparoscopy/exploratory laparotomy
Treatment algorithm
asymptomatic diverticulosis
symptomatic diverticular disease
symptomatic diverticulitis (uncomplicated)
symptomatic diverticulitis (complicated)
recurrent diverticulitis
Contributors
Authors
Mohamed A. Thaha, PhD, FRCS (Gen Surg), PG Cert Hlt Econ
Senior Lecturer & Consultant in Colorectal Surgery
National Bowel Research Centre
Blizard Institute
Barts and The London School of Medicine and Dentistry
Queen Mary University of London
The Royal London Hospital
Barts Health NHS Trust
London
UK
Disclosures
MAT declares that he has no competing interests.
Jayan Dewanta Jayasinghe, MD
International Senior Fellow in Colorectal Surgery
The Royal London Hospital
Barts Health NHS Trust
London
UK
Disclosures
JDJ declares that he has no competing interests.
Acknowledgements
Dr Mohamed A. Thaha and Dr Jayan D. Jayasinghe would like to gratefully acknowledge Dr Emma Carrington, Ms Kathryn Lynes, Professor Norman S. Williams, and Dr Abbasi Akhtar, the previous contributors to this topic.
Disclosures
EC has received honoraria for teaching, and acts as a consultant for Laborie Medical Management Systems. KL has received funding for a research fellowship from the David Johnston Fellowship through the Royal College of Surgeons of England. NSW is an author of a reference cited in this topic. AA declares that he has no competing interests.
Peer reviewers
Ned Snyder, MD, FACP
Professor of Medicine
Chief of Clinical Gastroenterology and Hepatology
University of Texas Medical Branch
Galveston
TX
Disclosures
NS declares that he has no competing interests.
Nicolas Regenet, MD
Clinic of digestive and endocrine surgery
University Hospital
Nantes
France
Disclosures
NR declares that he has no competing interests.
Differentials
- Endometriosis
- Colorectal cancer
- Appendicitis
More DifferentialsGuidelines
- Appropriateness criteria: left lower quadrant pain
- 2020 update of the WSES guidelines for the management of acute colonic diverticulitis in the emergency setting
More GuidelinesPatient information
Appendicitis
Constipation in adults
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