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Diverticular disease

Last reviewed: 18 Aug 2025
Last updated: 27 Feb 2025

Summary

Definition

History and exam

Key diagnostic factors

  • left lower quadrant abdominal pain
  • fever
Full details

Other diagnostic factors

  • guarding in left lower quadrant
  • tenderness in left lower quadrant
  • rebound tenderness
  • diffuse abdominal tenderness
  • change in bowel habit
  • palpable abdominal mass
Full details

Risk factors

  • age >50 years
  • low dietary fiber
  • diet rich in salt, meat, and sugar
  • obesity (BMI >30)
  • use of nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, or opioids
  • tobacco smoking
  • alcohol consumption
Full details

Investigações diagnósticas

Primeiras investigações a serem solicitadas

  • CBC with differential
  • CRP
  • basic metabolic panel
  • contrast CT scan of abdomen
Detalhes completos

Investigações a serem consideradas

  • blood culture
  • ABG and serum lactate
  • noncontrast CT scan of abdomen
  • abdominal ultrasound (graded-compression)
  • abdominal MRI scan
  • colonoscopy or sigmoidoscopy
  • diagnostic laparoscopy/exploratory laparotomy
Detalhes completos

Algoritmo de tratamento

AGUDA

asymptomatic diverticulosis

acute uncomplicated diverticulitis

acute complicated diverticulitis

CONTÍNUA

recurrent diverticulitis

Colaboradores

Autores

Marilyse Boutros, MD, FACS, FRCSC

Vice-Chair and Regional Director of Research for the Digestive Disease Institute, Cleveland Clinic Weston Hospital

Colorectal Surgeon, Cleveland Clinic Florida

Weston

FL

Clinical Affiliate Professor of Surgery, Florida Atlantic University

Boca Raton

FL

Professor of Surgery, McGill University

Montreal

Canada

Declarações

MB has received teaching honorarium from Ethicon and Johnson and Johnson.

Sameh Hany Emile, MBBCh, MSc, MD, FACS

Project Scientist

Department of Colorectal Surgery

Cleveland Clinic Florida

Weston

FL

Clinical Affiliate Associate Professor of Surgery

Florida Atlantic University

Boca Raton

FL

Associate Professor of Surgery

Mansoura University Faculty of Medicine

Mansoura City

Egypt

Declarações

SHE receives consultancy fees from Becton, Dickinson and Company.

Agradecimentos

Dr Marilyse Boutros and Dr Sameh Hany Emile would like to gratefully acknowledge Dr Mohamed A. Thaha, Dr Jayan D. Jayasinghe, Dr Emma Carrington, Ms Kathryn Lynes, Professor Norman S. Williams, and Dr Abbasi Akhtar, the previous contributors to this topic.

Declarações

MAT declares he has no competing interests. JDJ declares that he has no competing interests. EC has received honoraria for teaching, and acts as a consultant for Laborie Medical Management Systems. KL has received funding for a research fellowship from the David Johnston Fellowship through the Royal College of Surgeons of England. NSW is an author of a reference cited in this topic. AA declares that he has no competing interests.

Revisores

Ned Snyder, MD, FACP

Professor of Medicine

Chief of Clinical Gastroenterology and Hepatology

University of Texas Medical Branch

Galveston

TX

Declarações

NS declares that he has no competing interests.

Nicolas Regenet, MD

Clinic of digestive and endocrine surgery

University Hospital

Nantes

France

Declarações

NR declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

Referências

Nossas equipes internas de editoria e de evidências trabalham em conjunto com colaboradores internacionais especializados e pares revisores para garantir que forneçamos acesso às informações o mais clinicamente relevantes possível.

Principais artigos

Hall J, Hardiman K, Lee S, et al. The American Society of Colon and Rectal Surgeons clinical practice guidelines for the treatment of left-sided colonic diverticulitis. Dis Colon Rectum. 2020 Jun;63(6):728-47.Texto completo  Resumo

Sartelli M, Weber DG, Kluger Y, et al. 2020 update of the WSES guidelines for the management of acute colonic diverticulitis in the emergency setting. World J Emerg Surg. 2020 May 7;15(1):32.Texto completo  Resumo

Stollman N, Smalley W, Hirano I; AGA Institute Clinical Guidelines Committee. American Gastroenterological Association Institute guideline on the management of acute diverticulitis. Gastroenterology. 2015 Dec;149(7):1944-9.Texto completo  Resumo

Peery AF, Shaukat A, Strate LL. AGA clinical practice update on medical management of colonic diverticulitis: expert review. Gastroenterology. 2021 Feb;160(3):906-11.e1.Texto completo  Resumo

American College of Radiology. ACR appropriateness criteria: left lower quadrant pain. 2023 [internet publication].Texto completo

Qaseem A, Etxeandia-Ikobaltzeta I, Lin JS, et al; Clinical Guidelines Committee of the American College of Physicians. Diagnosis and management of acute left-sided colonic diverticulitis: a clinical guideline from the American College of Physicians. Ann Intern Med. 2022 Mar;175(3):399-415.Texto completo  Resumo

Artigos de referência

Uma lista completa das fontes referenciadas neste tópico está disponível para os usuários com acesso total ao BMJ Best Practice.
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  • Diretrizes

    • Diagnosis and management of acute left-sided colonic diverticulitis
    • 2020 update of the WSES guidelines for the management of acute colonic diverticulitis in the emergency setting
    Mais Diretrizes
  • Folhetos informativos para os pacientes

    Appendicitis

    Constipation in adults

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