Attention deficit hyperactivity disorder (ADHD) is a common childhood-onset disorder characterized by inattention, hyperactivity, and/or impulsivity demonstrated across 2 or more settings (such as home and school).
Several inattentive or hyperactive/impulsive symptoms must be present prior to 12 years of age, and 60% to 70% of patients have persistent functional impairment into adulthood.
Diagnosed by clinical history, which should include information from multiple sources, including parents, caregivers, and teachers.
Mainstay of treatment is stimulant medication, which can be effective in 85% of patients; nonstimulants are less often effective, but may have other advantages in terms of duration of action or in particular populations.
Stimulant medications have been associated with cardiovascular side effects. These should be monitored in children with heart conditions.
ADHD is a neurodevelopmental disorder characterized by inattention, hyperactivity, and impulsivity. It has a chronic course with symptoms that begin in early childhood but often persist into adult life. A key element of the definition is that symptoms manifest in two or more settings, for example in home and school, or home and work. As a result, ADHD can limit academic, interpersonal, and occupational success and can also lead to greater risk-taking and accidents. In addition, patients with ADHD are more likely to have coexisting psychiatric disorders such as oppositional defiant disorder (ODD), conduct disorder, substance abuse, and possibly mood and anxiety disorders, such as depression and mania.
This topic covers the management of ADHD in children only. Please see ADHD in adults for more information on adult care.
History and exam
Key diagnostic factors
- failure to give close attention to details or making careless mistakes in schoolwork, work, or other activities
- difficulty sustaining attention in tasks or play activities
- does not seem to listen when spoken to directly
- does not follow through on instructions and fails to finish schoolwork, chores, or duties in the workplace
- often has difficulty organizing tasks and activities
- avoids, dislikes, or is reluctant to engage in tasks that require sustained mental effort (such as schoolwork or homework)
- often loses things necessary for tasks or activities (e.g., toys, school assignments, pencils, books, or tools)
- easily distracted by extraneous stimuli
- forgetful in daily activities
- fidgets or taps with hands or feet or squirms in seat
- leaves seat in classroom or in other situations in which remaining seated is expected
- runs about or climbs excessively during inappropriate situations
- difficulty playing or engaging in leisure activities quietly
- often "on the go" or acts as if "driven by a motor"
- often talks excessively
- often blurts out answers before questions have been completed
- often has difficulty awaiting turn
- often interrupts or intrudes on others (e.g., butts into conversations or games)
Other diagnostic factors
- mild mood symptoms (dysphoria, mood lability, irritability, boredom)
- difficulty with peer interactions
- low self-esteem
- working memory (i.e., short-term memory) impairment
- processing speed impairment (i.e., the rate at which information is dealt with)
- family history of ADHD
- male sex
- low birth weight
- maternal nicotine use during pregnancy
- tic disorders
- maternal alcohol use during pregnancy
- stress during pregnancy and labor
- psychosocial adversity
- lead exposure
- traumatic brain injury
- severe early deprivation
- iron deficiency
1st investigations to order
- no formal laboratory or imaging studies
Investigations to consider
- neuropsychological testing
preschool-age children: 4-6 years
school-age children: 6-18 years
- Learning/language disorder
- Oppositional defiant disorder
- Diagnostic and Statistical Manual of Mental Disorders, 5th edition, Text Revision (DSM-5-TR)
- Clinical practice guideline for the diagnosis, evaluation, and treatment of attention-deficit/hyperactivity disorder in children and adolescents
ADHD: what is it?
ADHD in children: what treatments work?More Patient leaflets
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