Caused by infestation with Sarcoptes scabiei , a 0.3- to 0.5-mm mite that can burrow and deposit eggs in the human stratum corneum.
Transmission usually occurs via direct skin-to-skin contact, seen most commonly in overcrowded living conditions.
Clinical features include pruritus, erythematous papules, and linear burrows in the interdigital web space and red nodules on the penis, with patients often reporting history of exposure to an infested individual.
Microscopic visualization of mites, their eggs, or feces in skin scrapings is helpful but not essential to initiation of treatment.
Most popular treatment options include topical permethrin and oral ivermectin.
Primarily considered a nuisance in the developed world. Children in the developing world can contract secondary streptococcal infection in their skin lesions, with potential complications of rheumatic heart disease or poststreptococcal glomerulonephritis.
Scabies is caused by infestation with the ectoparasite Sarcoptes scabiei , a mite that burrows through the human stratum corneum. Spread is primarily via direct contact with an infested individual. Clinical clues to diagnosis include intense pruritus and linear erythematous burrows, particularly on the extremities, or erythematous papules and nodules elsewhere such as in the axilla or genital area. Rarely, it can present on the neck and scalp. Diagnosis is based on history and clinical appearance. Confirmation by microscopic visualization of the mite, its eggs, or feces on skin scraping is helpful but not necessary. 
Department of Dermatology
University of Pittsburgh
LKF declares that she has no competing interests.
Dermatology Center of Canyon County
RH declares that he has no competing interests.
Dr Laura Korb Ferris and Dr Ryan Harris would like to gratefully acknowledge Dr Pooja Khera, a previous contributor to this monograph. PK declares that she has no competing interests.
Department of Pathology and Laboratory Medicine
University of California
DC declares that he has no competing interests.
International Foundation of Dermatology
RJH declares that he has no competing interests.
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