Upper airway cough syndrome

American College of Chest Physicians. Diagnosis and Management of Cough. ​Chronic upper airway cough syndrome secondary to rhinosinus diseases (previously referred to as postnasal drip syndrome): ACCP evidence-based clinical practice guidelines. Jan 2006 [internet publication].Full text

European Respiratory Society. ERS guidelines on the diagnosis and treatment of chronic cough in adults and children. 2020 [internet publication]. Full text

American College of Chest Physicians. Treatment of unexplained chronic cough: CHEST guideline and expert panel report. 2016 [internet publication].Full text

1. American College of Chest Physicians. Diagnosis and Management of Cough. ​Chronic upper airway cough syndrome secondary to rhinosinus diseases (previously referred to as postnasal drip syndrome): ACCP evidence-based clinical practice guidelines. Jan 2006 [internet publication].Full text

2. Macedo P, Saleh H, Torrego A, et al. Postnasal drip and chronic cough: an open interventional study. Respir Med. 2009 Nov;103(11):1700-5.Full text  Abstract

3. Morice AH. Post-nasal drip syndrome - a symptom to be sniffed at? Pulm Pharmacol Ther. 2004;17(6):343-5. Abstract

4. Morice AH, Millqvist E, Belvisi MG, et al. Expert opinion on the cough hypersensitivity syndrome in respiratory medicine. Eur Respir J. 2014 Nov;44(5):1132-48.Full text  Abstract

5. Meltzer EO, Zeiger RS, Dicpinigaitis P, et al. Prevalence and burden of chronic cough in the United States. J Allergy Clin Immunol Pract. 2021 Nov;9(11):4037-44.e2. Abstract

6. Liang H, Ye W, Wang Z, et al. Prevalence of chronic cough in China: a systematic review and meta-analysis. BMC Pulm Med. 2022 Feb 12;22(1):62.Full text  Abstract

7. Chung KF, Pavord ID. Prevalence, pathogenesis, and causes of chronic cough. Lancet 2008 Apr 19;371(9621):1364-74. Abstract

8. Mello CJ, Irwin RS, Curley FJ. Predictive values of the character, timing, and complications of chronic cough in diagnosing its cause. Arch Intern Med. 1996 May 13;156(9):997-1003. Abstract

9. Irwin RS, Corrao WM, Pratter MR. Chronic persistent cough in the adult: the spectrum and frequency of causes and successful outcome of specific therapy. Am Rev Respir Dis. 1981 Apr;123(4 Pt 1):413-7. Abstract

10. Kohno S, Ishida T, Uchida Y, et al. The Japanese Respiratory Society guidelines for management of cough. Respirology. 2006 Sep;11 Suppl 4:S135-86. Abstract

11. Niimi A, Torrego A, Nicholson AG, et al. Nature of airway inflammation and remodeling in chronic cough. J Allergy Clin Immunol. 2005 Sep;116(3):565-70.Full text  Abstract

12. O'Hara J, Jones NS. "Post-nasal drip syndrome": most patients with purulent nasal secretions do not complain of chronic cough. Rhinology. 2006 Dec;44(4):270-3. Abstract

13. Morice AH. Chronic cough hypersensitivity syndrome. Cough. 2013 May 13;9(1):14.Full text  Abstract

14. Chung KF, McGarvey L, Mazzone SB. Chronic cough as a neuropathic disorder. Lancet Respir Med. 2013 Jul;1(5):414-22. Abstract

15. Hull JH, Backer V, Gibson PG, et al. Laryngeal dysfunction: assessment and management for the clinician. Am J Respir Crit Care Med. 2016 Nov 1;194(9):1062-72.Full text  Abstract

16. Braunstahl GJ, Overbeek SE, Fokkens WJ, et al. Segmental bronchoprovocation in allergic rhinitis patients affects mast cell and basophil numbers in nasal and bronchial mucosa. Am J Respir Crit Care Med. 2001 Sep 1;164(5):858-65.Full text  Abstract

17. Tarlo SM. Cough: occupational and environmental considerations: ACCP evidence-based clinical practice guidelines. Chest. 2006 Jan;129(1 suppl):186S-96S.Full text  Abstract

18. Dicpinigaitis PV. Angiotensin-converting enzyme inhibitor-induced cough: ACCP evidence-based clinical practice guidelines. Chest. 2006 Jan;129(1 suppl):169S-73S.Full text  Abstract

19. Irwin RS, Baumann MH, Bolser DC, et al. Diagnosis and management of cough executive summary: ACCP evidence-based clinical practice guidelines. Chest. 2006 Jan;129(1 Suppl):1S-23S.Full text  Abstract

20. Vertigan AE, Kapela SM, Kearney EK, et al. Laryngeal dysfunction in cough hypersensitivity syndrome: a cross-sectional observational study. J Allergy Clin Immunol Pract. 2018 Nov-Dec;6(6):2087-95. Abstract

21. Vertigan AE, Bone SL, Gibson PG. Development and validation of the Newcastle laryngeal hypersensitivity questionnaire. Cough. 2014 Feb 19;10(1):1.Full text  Abstract

22. Brozek JL, Bousquet J, Baena-Cagnani CE, et al. Allergic rhinitis and its impact on asthma (ARIA) guidelines: 2010 revision. J Allergy Clin Immunol. 2010 Sep;126(3):466-76.Full text  Abstract

23. American College of Radiology. ACR appropriateness criteria: chronic cough.​ 2021 [internet publication].Full text

24. Bucca CB, Bugiani M, Culla B, et al. Chronic cough and irritable larynx. J Allergy Clin Immunol. 2011 Feb;127(2):412-9.Full text  Abstract

25. Bucca C, Rolla G, Brussino L, et al. Are asthma-like symptoms due to bronchial or extrathoracic airway dysfunction? Lancet. 1995 Sep 23;346(8978):791-5. Abstract

26. European Respiratory Society. ERS guidelines on the diagnosis and treatment of chronic cough in adults and children. 2020 [internet publication]. Full text

27. Pratter MR, Bartter T, Akers S, et al. An algorithmic approach to chronic cough. Ann Intern Med. 1993 Nov 15;119(10):977-83. Abstract

28. European Medicines Agency. Pseudoephedrine-containing medicinal products - referral. Jan 2024 [internet publication].Full text

29. Fokkens WJ, Lund VJ, Mullol J, et al. EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists. Rhinology. 2012 Mar;50(1):1-12. Abstract

30. US Food & Drug Administration. FDA requires Boxed Warning about serious mental health side effects for asthma and allergy drug montelukast (Singulair); advises restricting use for allergic rhinitis. 4 March 2020 [internet publication].Full text

31. Pawar S, Lim HJ, Gill M, et al. Treatment of postnasal drip with proton pump inhibitors: a prospective, randomized, placebo-controlled study. Am J Rhinol. 2007 Nov-Dec;21(6):695-701. Abstract

32. American College of Chest Physicians. Treatment of unexplained chronic cough: CHEST guideline and expert panel report. 2016 [internet publication].Full text

33. Vertigan AE, Theodoros DG, Gibson PG, et al. Efficacy of speech pathology management for chronic cough: a randomised placebo controlled trial of treatment efficacy. Thorax. 2006 Dec;61(12):1065-9.Full text  Abstract

34. Ryan NM, Vertigan AE, Bone S, et al. Cough reflex sensitivity improves with speech language pathology management of refractory chronic cough. Cough. 2010 Jul 28;6:5.Full text  Abstract

35. Chamberlain S, Birring SS, Garrod R. Nonpharmacological interventions for refractory chronic cough patients: systematic review. Lung. 2014 Feb;192(1):75-85. Abstract

36. Ryan NM, Birring SS, Gibson PG. Gabapentin for refractory chronic cough: a randomised, double-blind, placebo-controlled trial. Lancet. 2012 Nov 3;380(9853):1583-9. Abstract

37. Smith JA, Kitt MM, Morice AH, et al. MK-7264, a P2X3 receptor antagonist, reduces cough frequency in patients with refractory chronic cough: results from a randomized, controlled, phase 2b clinical trial. Am J Respir Crit Care Med. 2017;195:A7608.

38. McGarvey LP, Birring SS, Morice AH, et al. Efficacy and safety of gefapixant, a P2X(3) receptor antagonist, in refractory chronic cough and unexplained chronic cough (COUGH-1 and COUGH-2): results from two double-blind, randomised, parallel-group, placebo-controlled, phase 3 trials. Lancet. 2022 Mar 5;399(10328):909-23. Abstract

39. Irwin RS. Complications of cough: ACCP evidence-based clinical practice guidelines. Chest. 2006 Jan;129(1 suppl):54S-8S.Full text  Abstract