Evaluation of hypotension


Key articles

Gibson SJ, Helme RD. Age-related differences in pain perception and report. Clin Geriatr Med. 2001 Aug;17(3):433-56, v-vi. Abstract

Monnet X, Marik P, Teboul JL. Passive leg raising for predicting fluid responsiveness: a systematic review and meta-analysis. Intensive Care Med. 2016 Dec;42(12):1935-47. Abstract

Kamaruzzaman S, Watt H, Carson C, et al. The association between orthostatic hypotension and medication use in the British Women's Heart and Health Study. Age Ageing. 2010 Jan;39(1):51-6. Abstract

Reference articles

1. Gibson SJ, Helme RD. Age-related differences in pain perception and report. Clin Geriatr Med. 2001 Aug;17(3):433-56, v-vi. Abstract

2. Sigurdsson E, Thorgeirsson G, Sigvaldason N. Unrecognised myocardial infarction: epidemiology, clinical characteristics and the prognostic role of angina pectoris. The Reykjavik Study. Ann Intern Med. 1995 Jan 15;122(2):96-102. Abstract

3. Williams B, Mancia G, Spiering W, et al. 2018 Practice guidelines for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension. Blood Press. 2018 Dec;27(6):314-40. Abstract

4. Frith J. Diagnosing orthostatic hypotension: a narrative review of the evidence. Br Med Bull. 2015 Sep;115(1):123-34.Full text  Abstract

5. Freeman R, Wieling W, Axelrod FB, et al. Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome. Clin Auton Res. 2011 Apr;21(2):69-72. Abstract

6. Haerlein J, Dassen T, Halfens RJ, et al. Fall risk factors in older people with dementia or cognitive impairment: a systematic review. J Adv Nurs. 2009 May;65(5):922-33. Abstract

7. Corsinovi L, Bo M, Ricauda- Aimonino N, et al. Outcomes in elderly patients admitted to an acute geriatric unit. Arch Gerontol Geriatr. 009 Jul-Aug;49(1):142-5. Abstract

8. Rose BD, Post TW. Hypovolemic states. In: Clinical physiology of acid-base and electrolyte disorders. 5th ed. New York, NY: McGraw-Hill; 2001:415-46.

9. McGee S, Abernethy WB 3rd, Simel DL. The rational clinical examination: is this patient hypovolemic? JAMA. 1999;281:1022-1029. Abstract

10. Portilla D, Andreoli TE. Disorders of extracellular volume. In: Johnson RJ, Feehally J, eds. Comprehensive clinical nephrology. London: Mosby International; 2007:77-91.

11. Gitz Holler J, Jensen HK, Henriksen DP, et al. Etiology of shock in the emergency department: A 12-year population-based cohort study. Shock. 2019 Jan;51(1):60-67.Full text  Abstract

12. Hochman JS. Cardiogenic shock complicating acute myocardial infarction: expanding the paradigm. Circulation. 2003 Jun 24;107(24):2998-3002.Full text  Abstract

13. Standl T, Annecke T, Cascorbi I, et al. The nomenclature, definition and distinction of types of shock. Dtsch Arztebl Int. 2018 Nov 9;115(45):757-768.Full text  Abstract

14. Hines OJ, Pandol SJ. Management of severe acute pancreatitis. BMJ. 2019 Dec 2;367:l6227.Full text  Abstract

15. Asplund CA, O'Connor F G, Noakes TD. Exercise-associated collapse: an evidence-based review and primer for clinicians. Br J Sports Med. 2011 Nov;45(14):1157-62.Full text  Abstract

16. Cecconi M, De Backer D, Antonelli M, et al. Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine. Intensive Care Med. 2014 Dec;40(12):1795-815.Full text  Abstract

17. O'Driscoll BR, Howard LS, Earis J, et al. BTS guideline for oxygen use in adults in healthcare and emergency settings. Thorax. 2017 Jun;72(suppl 1):ii1-90.Full text  Abstract

18. Hasler RM, Nuesch E, Jüni P, et al. Systolic blood pressure below 110 mmHg is associated with increased mortality in blunt major trauma patients: multicentre cohort study. Resuscitation. 2011 Sep;82(9):1202-7. Abstract

19. Wada H, Matsumoto T, Yamashita Y, et al. Diagnosis and treatment of disseminated intravascular coagulation (DIC) according to four DIC guidelines. J Intensive Care. 2014 Feb 20;2(1):15.Full text  Abstract

20. Innerhofer P, Fries D, Mittermayr M, et al. Reversal of trauma-induced coagulopathy using first-line coagulation factor concentrates or fresh frozen plasma (RETIC): a single-centre, parallel-group, open-label, randomised trial. Lancet Haematol. 2017 Jun;4(6):e258-71. Abstract

21. Papageorgiou C, Jourdi G, Adjambri E, et al. Disseminated Intravascular Coagulation: An Update on Pathogenesis, Diagnosis, and Therapeutic Strategies. Clin Appl Thromb Hemost. 2018 Dec;24(9_suppl):8S-28S.Full text  Abstract

22. Pollack CV Jr, Reilly PA, van Ryn J, et al. Idarucizumab for dabigatran reversal: full cohort analysis. N Engl J Med. 2017 Aug 3;377(5):431-41. Abstract

23. Gayet-Ageron A, Prieto-Merino D, Ker K, et al. Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients. Lancet. 2018 Jan 13;391(10116):125-32.Full text  Abstract

24. Chu DK, Kim LH, Young PJ, et al. Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis. Lancet. 2018 Apr 28;391(10131):1693-1705. Abstract

25. O'Gara PT, Kushner FG, Ascheim DD, et al. 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2013 Jul 1;82(1):E1-27.Full text  Abstract

26. McDonagh TA, Metra M, Adamo M, et al. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J. 2021 Sep 21;42(36):3599-3726. Abstract

27. Stein PD, Gottschalk A, Saltzman MA, et al. Diagnosis of acute pulmonary embolism in the elderly. J Am Coll Cardiol. 1991 Nov 15;18(6):1452-7. Abstract

28. American College of Surgeons. Advanced Trauma Life Support Student Course Manual. 2018 10th edition. 2018 [internet publication].

29. National Patient Safety Agency. Alert: Blood control safety cannula and needle thoracostomy for tension pneumothorax. April 2020 [internet publication].Full text

30. Leigh-Smith S, Harris T. Tension pneumothorax - time for a re-think? Emerg Med J. 2005 Jan;22(1):8-16.Full text  Abstract

31. Jones R, Hollingsworth J. Tension pneumothoraces not responding to needle thoracocentesis. Emerg Med J. 2002 Mar;19(2):176-7.Full text  Abstract

32. Singer M, Deutschman CS, Seymour CW, et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 2016 Feb 23;315(8):801-10.Full text  Abstract

33. National Institute for Health and Care Excellence. Sepsis: recognition, diagnosis and early management. Sept 2017 [internet publication].Full text

34. Warmerdam M, Baris L, van Liebergen M, et al. The association between systolic blood pressure and in-hospital mortality in older emergency department patients who are hospitalised with a suspected infection. Emerg Med J. 2018 Oct;35(10):619-622.Full text  Abstract

35. Royal College of Physicians. National Early Warning Score (NEWS) 2. December 2017 [internet publication].Full text

36. American College of Emergency Physicians (ACEP) Expert Panel on Sepsis. DART: an evidence-driven tool to guide the early recognition and treatment of sepsis and septic shock. [internet publication].Full text

37. Matson PL, Turner SR, Yovich JM, et al. Oligospermic infertility treated by in-vitro fertilization. Aust N Z J Obstet Gynaecol. 1986 Feb;26(1):84-7.Full text  Abstract

38. Society of Critical Care Medicine; European Society of Intensive Care Medicine. Surviving Sepsis Campaign: hour-1 bundle. Initial resuscitation for sepsis and septic shock. 2019 [internet publication]

39. Lavonas EJ, Drennan IR, Gabrielli A, et al. Part 10: Special circumstances of resuscitation: 2015 American Heart Association guidelines update for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2015 Nov 3;132(18 Suppl 2):S501-18.Full text  Abstract

40. Resuscitation Council UK. Guidance: Anaphylaxis. 2021 [internet publication].Full text

41. European Resuscitation Council. ERC Guidelines. 2021 [internet publication].Full text

42. Rushworth RL, Torpy DJ, Falhammar H. Adrenal Crisis. N Engl J Med. 2019 Aug 29;381(9):852-61.Full text  Abstract

43. Pinsky MR. Hemodynamic evaluation and monitoring in the ICU. Chest. 2007 Dec;132(6):2020-9. Abstract

44. Rady MY, Rivers EP, Nowak RM. Resuscitation of the critically ill in the ED: responses of blood pressure, heart rate, shock index, central venous oxygen saturation, and lactate. Am J Emerg Med. 1996 Mar;14(2):218-25. Abstract

45. Monnet X, Marik P, Teboul JL. Passive leg raising for predicting fluid responsiveness: a systematic review and meta-analysis. Intensive Care Med. 2016 Dec;42(12):1935-47. Abstract

46. Marik PE, Lemson J. Fluid responsiveness: an evolution of our understanding. Br J Anaesth. 2014 Apr;112(4):617-20.Full text  Abstract

47. Atkinson P, Bowra J, Milne J, et al. International Federation for Emergency Medicine Consensus Statement: Sonography in hypotension and cardiac arrest (SHoC): An international consensus on the use of point of care ultrasound for undifferentiated hypotension and during cardiac arrest. CJEM. 2017 Nov;19(6):459-70.Full text  Abstract

48. Atkinson PR, Milne J, Diegelmann L, et al. Does point-of-care ultrasonography improve clinical outcomes in emergency department patients with undifferentiated hypotension? An international randomized controlled trial from the SHoC-ED investigators. Ann Emerg Med. 2018 Oct;72(4):478-489.Full text  Abstract

49. Warren J, Moazzez A, Chong V, et al. Narrowed pulse pressure predicts massive transfusion and emergent operative intervention following penetrating trauma. Am J Surg. 2019 Dec;218(6):1185-1188.Full text  Abstract

50. Reynolds HR, Hochman JS. Cardiogenic shock: current concepts and improving outcomes. Circulation. 2008 Feb 5;117(5):686-97.Full text  Abstract

51. Clinch D, Banerjee AK, Ostick G. Absence of abdominal pain in elderly patients with peptic ulcer disease. Age Ageing. 1984 Mar;13(2):120-3. Abstract

52. Liston R, McLoughlin R, Clinch D. Acute pneumothorax: A comparison of elderly with younger patients. Age Ageing. 1994 Sep;23(5):393-5. Abstract

53. Kuipers J, Verboom LM, Ipema KJR, et al. The prevalence of intradialytic hypotension in patients on conventional hemodialysis: A systematic review with meta-analysis. Am J Nephrol. 2019;49(6):497-506.Full text  Abstract

54. Kamaruzzaman S, Watt H, Carson C, et al. The association between orthostatic hypotension and medication use in the British Women's Heart and Health Study. Age Ageing. 2010 Jan;39(1):51-6. Abstract

55. Wynne HA, Schofield S. Drug-induced orthostatic hypotension. In: Kenny RA ,ed. Syncope in the older patient: causes, investigations and consequences of syncope and falls. London: Chapman & Hall. 1996:137-54.

56. Maxwell EN, Johnson B, Cammilleri J, et al. Intravenous acetaminophen-induced hypotension: A review of the current literature. Ann Pharmacother. 2019 Oct;53(10):1033-1041.Full text  Abstract

57. Heidenreich PA, Bozkurt B, Aguilar D, et al. 2022 AHA/ACC/HFSA guideline for the management of heart failure: a report of the American College of Cardiology/American Heart Association joint committee on clinical practice guidelines. Circulation. 2022 May 3;145(18):e895-e1032.Full text  Abstract

58. Hanna FWF, Issa BG, Kevil B, et al. Investigating cortisol excess or deficiency: a practical approach. BMJ. 2019 Nov 26;367:l6039.Full text  Abstract

59. National Institute for Health and Care Excellence. Anaphylaxis: assessment and referral after emergency treatment. Aug 2020 [internet publication].Full text

60. Kusminsky RE. Complications of central venous catheterization. J Am Coll Surg. 2007 Apr;204(4):681-96. Abstract

61. McGee DC, Gould MK. Preventing complications of central venous catheterization. N Engl J Med. 2003 Mar 20;348(12):1123-33.Full text  Abstract

62. Smith RN, Nolan JP. Central venous catheters. BMJ. 2013 Nov 11;347:f6570.Full text  Abstract

63. Reich DL. Monitoring in anesthesia and perioperative care. Cambridge: Cambridge University Press; 2011.

64. Abbott Northwestern Hospital Internal Medicine Residency. Internal jugular central venous line. 2015 [internet publication].Full text

65. Bishop L, Dougherty L, Bodenham A, et al. Guidelines on the insertion and management of central venous access devices in adults. Int J Lab Hematol. 2007 Aug;29(4):261-78. Abstract

66. Practice guidelines for central venous access 2020: an updated report by the American Society of Anesthesiologists Task Force on Central Venous Access. Anesthesiology. 2020 Jan;132(1):8-43.Full text  Abstract

67. Fletcher SJ, Bodenham AR. Safe placement of central venous catheters: where should the tip of the catheter lie? Br J Anaesth. 2000 Aug;85(2):188-91. Abstract

68. Gibson F, Bodenham A. Misplaced central venous catheters: applied anatomy and practical management. Br J Anaesth. 2013 Mar;110(3):333-46.Full text  Abstract

69. Schuster M, Nave H, Piepenbrock S, et al. The carina as a landmark in central venous catheter placement. Br J Anaesth. 2000 Aug;85(2):192-4. Abstract

70. Webster J, Osborne S, Rickard CM, et al. Clinically-indicated replacement versus routine replacement of peripheral venous catheters. Cochrane Database Syst Rev. 2019 Jan 23;(1):CD007798.Full text  Abstract

71. Wieling W, Thijs RD, van Dijk N, et al. Symptoms and signs of syncope: a review of the link between physiology and clinical clues. Brain. 2009 Oct;132(Pt 10):2630-42. Abstract

72. Brignole M, Moya A, de Lange FJ, et al. 2018 ESC Guidelines for the diagnosis and management of syncope. Eur Heart J. 2018 Jun 1;39(21):1883-1948.Full text  Abstract

73. Bannister R. Chronic autonomic failure with postural hypotension. Lancet. 1979 Aug 25;2(8139):404-6. Abstract

74. Mathias CJ, Bannister R. Clinical features and evaluation of the primary chronic autonomic failure syndromes. In: Bannister R, Mathias CJ eds. Autonomic failure: A textbook of clinical disorders of the autonomic nervous system. 4th ed. New York, NY: Oxford University Press;1999:562

75. Wang AK, Fealey RD, Gehrking TL, et al. Patterns of neuropathy and autonomic failure in patients with amyloidosis. Mayo Clin Proc. 2008 Nov;83(11):1226-30.Full text  Abstract

76. Hiorth YH, Pedersen KF, Dalen I, et al. Orthostatic hypotension in Parkinson disease: A 7-year prospective population-based study. Neurology. 2019 Oct 15;93(16):e1526-e1534.Full text  Abstract

77. Moore A, Ryan J, Watts M et al. Orthostatic tolerance in older patients with vitamin B12 deficiency before and after vitamin B12 replacement. Clin Auton Res. 2004 Apr;14(2):67-71. Abstract

78. Sarasin FP, Louis-Simonet M, Caraballo D, et al. Prevalence of orthostatic hypotension among patients with syncope in the ED. Am J Emerg Med. 2002 Oct;20(6):497-501. Abstract

79. Kenny RA, Richardson DA. Carotid sinus syndrome and falls in older adults. Am J Geriatr Cardiol. 2001 Mar-Apr;10(2):97-9. Abstract

80. Kenny RA, Bayliss J, Ingram A, et al. Head-Up tilt table testing: a useful test for investigating unexplained falls. Lancet. 1986;i:1352-54.

81. Kearney F, Moore A, Donegan C. Orthostatic hypotension in older adults. Rev Clin Gerontol. 2007;17(4):259-75.

82. Batlle D, Chen S, Haque S. Physiological principles in the clinical evaluation of electrolyte, water, and acid-base disorders. In: Alpern RJ, Caplan MJ, Moe OW, eds. Seldin and Giebisch's the kidney: physiology and pathophysiology. 5th ed. San Diego, CA: Academic Press; 2012:2477-512.

83. Oakland K, Chadwick G, East JE, et al. Diagnosis and management of acute lower gastrointestinal bleeding: guidelines from the British Society of Gastroenterology. Gut. 2019 May;68(5):776-89.Full text  Abstract

84. Siegel CL, Cohan RH, Korobkin M, et al. Abdominal aortic aneurysm morphology: CT features in patients with ruptured and nonruptured aneurysms. AJR Am J Roentgenol. 1994 Nov;163(5):1123-9.Full text  Abstract

85. Dent B, Kendall RJ, Boyle AA, et al. Emergency ultrasound of the abdominal aorta by UK emergency physicians: a prospective cohort study. Emerg Med J. 2007 Aug;24(8):547-9. Abstract

86. Rompianesi G, Hann A, Komolafe O, et al. Serum amylase and lipase and urinary trypsinogen and amylase for diagnosis of acute pancreatitis. Cochrane Database Syst Rev. 2017 Apr 21;4:CD012010.Full text  Abstract

87. The PIOPED Investigators. Value of the ventilation/perfusion scan in acute pulmonary embolism. Results of the prospective investigation of pulmonary embolism diagnosis (PIOPED). JAMA. 1990 May 23-30;263(20):2753-9. Abstract

88. Hassan SA, Banchs J, Iliescu C, et al. Carcinoid heart disease. Heart. 2017 Oct;103(19):1488-95. Abstract

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