Summary
Definition
History and exam
Key diagnostic factors
- hematemesis
Other diagnostic factors
- light-headedness/dizziness
- postural/orthostatic hypotension
- dysphagia
- odynophagia
- pain
- melena
- hematochezia
- shock
- signs of anemia
Risk factors
- condition predisposing to retching, vomiting, and/or straining
- chronic cough
- hiatus hernia
- retching during endoscopy or other instrumentation
- significant alcohol use
- previous instrumentation
- age 30 to 50 years
- male sex
- aspirin or other nonsteroidal anti-inflammatory drug ingestion
- hiccups
- blunt abdominal trauma
- cardiopulmonary resuscitation
Diagnostic tests
1st tests to order
- complete blood count (CBC)
- blood urea nitrogen (BUN)
- liver function test (LFT)
- prothrombin time/international normalized ratio (PT/INR)
- partial thromboplastin time (PTT)
- chest x-ray (CXR)
- esophagogastroduodenoscopy (EGD)
- cross matching/blood grouping
Tests to consider
- creatine kinase (CK)
- creatine kinase-MB (CK-MB)
- troponin
- ECG
- angiography
Treatment algorithm
all patients
Contributors
Authors
Douglas G. Adler, MD, FACG, AGAF, FASGE
Professor of Medicine
Division of Gastroenterology
Department of Internal Medicine
Huntsman Cancer Institute
University of Utah
Salt Lake City
UT
Disclosures
DGA is a consultant for BSC, Merit, Cook, and Olympus.
Acknowledgements
Dr Douglas Adler would like to gratefully acknowledge Dr Shilpa Reddy and Dr Juan Carlos Munoz, the previous contributors to this topic.
Disclosures
SR and JCM declare that they have no competing interests.
Peer reviewers
Joseph Sung, MD
Professor of Medicine
Department of Medicine and Therapeutics
Director
Institute of Digestive Disease
The Chinese University of Hong Kong
Hong Kong
Disclosures
JS declares that he has no competing interests.
Imtiyaz Mohammed, MD
Consultant Gastroenterologist
Sandwell General Hospital
Lyndon
West Bromwich
UK
Disclosures
IM declares that he has no competing interests.
Differentials
- Esophagitis
- Spontaneous esophageal perforation (Boerhaave syndrome)
- Cameron erosions
More DifferentialsGuidelines
- Management of anticoagulants and antiplatelets during acute gastrointestinal bleeding and the periendoscopic period
- Management of nonvariceal upper gastrointestinal bleeding
More GuidelinesPatient information
Bulimia
Hernia
More Patient informationCalculators
Blatchford score for gastrointestinal bleeding
Rockall Score for Upper Gastrointestinal Bleeding
More Calculators- Log in or subscribe to access all of BMJ Best Practice
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