Placental abruption


Key articles

American College of Radiology. ACR appropriateness criteria: second and third trimester bleeding. 2020 [internet publication].Full text

Society for Maternal-Fetal Medicine (SMFM), Gyamfi-Bannerman C. Society for Maternal-Fetal Medicine (SMFM) Consult Series #44: Management of bleeding in the late preterm period. Am J Obstet Gynecol. 2018 Jan;218(1):B2-8.Full text  Abstract

Reference articles

1. Oyelese Y, Ananth CV. Placental abruption. Obstet Gynecol. 2006 Oct;108(4):1005-16. Abstract

2. Ananth CV, Lavery JA, Vintzileos AM, et al. Severe placental abruption: clinical definition and associations with maternal complications. Am J Obstet Gynecol. 2016 Feb;214(2):272.e1-272.Full text  Abstract

3. Ananth CV, Keyes KM, Hamilton A, et al. An international contrast of rates of placental abruption: an age-period-cohort analysis. PLoS One. 2015 May 27;10(5):e0125246.Full text  Abstract

4. Tikkanen M. Placental abruption: epidemiology, risk factors and consequences. Acta Obstet Gynecol Scand. 2011 Feb;90(2):140-9. Abstract

5. Ventolini G, Samlowski R, Hood DL. Placental findings in low-risk, singleton, term pregnancies after uncomplicated deliveries. Am J Perinatol. 2004 Aug;21(6):325-8. Abstract

6. Ananth CV, Oyelese Y, Yeo L, et al. Placental abruption in the United States, 1979 through 2001: temporal trends and potential determinants. Am J Obstet Gynecol. 2005 Jan;192(1):191-8. Abstract

7. Ananth CV, Oyelese Y, Prasad V, et al. Evidence of placental abruption as a chronic process: associations with vaginal bleeding early in pregnancy and placental lesions. Eur J Obstet Gynecol Reprod Biol. 2006 Sep-Oct;128(1-2):15-21. Abstract

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9. Harrington K, Cooper D, Lees C, et al. Doppler ultrasound of the uterine arteries: the importance of bilateral notching in the prediction of pre-eclampsia, placental abruption or delivery of a small-for-gestational-age baby. Ultrasound Obstet Gynecol. 1996 Mar;7(3):182-8. Abstract

10. Dommisse J, Tiltman AJ. Placental bed biopsies in placental abruption. Br J Obstet Gynaecol. 1992 Aug;99(8):651-4. Abstract

11. Ananth CV, Peltier MR, Chavez MR, et al. Recurrence of ischemic placental disease. Obstet Gynecol. 2004 Jun 1;103(11):4003-9. Abstract

12. Brenner B. Clinical management of thrombophilia-related placental vascular complications. Blood. 2004 Jun 1;103(11):4003-9. Abstract

13. ACOG Practice Bulletin No. 197: Inherited Thrombophilias in Pregnancy. Obstet Gynecol. 2018 Jul;132(1):e18-e34. Abstract

14. Ananth CV, Smulian JC, Vintzileos AM. Incidence of placental abruption in relation to cigarette smoking and hypertensive disorders during pregnancy: a meta-analysis of observational studies. Obstet Gynecol.1999 Apr;93(4):622-8. Abstract

15. Zetterstrom K, Lindeberg SN, Haglund B, et al. Maternal complications in women with chronic hypertension: a population-based cohort study. Acta Obstet Gynecol Scand. 2005 May;84(5):419-24. Abstract

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18. Tikkanen M, Nuutila M, Hiilesmaa V, et al. Clinical presentation and risk factors of placental abruption. Acta Obstet Gynecol Scand. 2006;85(6):700-5. Abstract

19. Bhattacharya S, Campbell DM. The incidence of severe complications of preeclampsia. Hypertens Pregnancy. 2005;24(2):181-90. Abstract

20. Tikkanen M, Nuutila M, Hiilesmaa V, et al. Prepregnancy risk factors for placental abruption. Acta Obstet Gynecol Scand. 2006;85(1):40-4. Abstract

21. Shobeiri F, Masoumi SZ, Jenabi E. The association between maternal smoking and placenta abruption: a meta-analysis. J Matern Fetal Neonatal Med. 2017 Aug;30(16):1963-7. Abstract

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23. Landy HJ, Hinson J. Placental abruption associated with cocaine use: case report. Reprod Toxicol. 1987-1988;1(3):203-5. Abstract

24. Addis A, Moretti ME, Ahmed Syed F, et al. Fetal effects of cocaine: an updated meta-analysis. Reprod Toxicol. 2001 Jul-Aug;15(4):341-69. Abstract

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27. Schiff MA, Holt VL. Pregnancy outcomes following hospitalization for motor vehicle crashes in Washington State from 1989 to 2001. Am J Epidemiol. 2005 Mar 15;161(6):503-10.Full text  Abstract

28. El-Kady D, Gilbert WM, Anderson J, et al. Trauma during pregnancy: an analysis of maternal and fetal outcomes in a large population. Am J Obstet Gynecol. 2004 Jun;190(6):1661-8. Abstract

29. Getahun D, Oyelese Y, Salihu HM, et al. Previous cesarean delivery and risks of placenta previa and placental abruption. Obstet Gynecol. 2006 Apr;107(4):771-8. Abstract

30. Lydon-Rochelle M, Holt VL, Easterling TR, et al. First-birth cesarean and placental abruption or previa at second birth(1). Obstet Gynecol. 2001 May;97(5 Pt 1):765-9. Abstract

31. Yang Q, Wen SW, Oppenheimer L, et al. Association of caesarean delivery for first birth with placenta praevia and placental abruption in second pregnancy. BJOG. 2007 May;114(5):609-13. Abstract

32. Ananth CV, Oyelese Y, Srinivas N, et al. Preterm premature rupture of membranes, intrauterine infection, and oligohydramnios: risk factors for placental abruption. Obstet Gynecol. 2004 Jul;104(1):71-7. Abstract

33. Kramer MS, Usher RH, Pollack R, et al. Etiologic determinants of abruptio placentae. Obstet Gynecol. 1997 Feb;89(2):221-6. Abstract

34. Hung TH, Hsieh CC, Hsu JJ, et al. Risk factors for placental abruption in an Asian population. Reprod Sci. 2007 Jan;14(1):59-65. Abstract

35. Rasmussen S, Irgens LM, Dalaker K. Outcome of pregnancies subsequent to placental abruption: a risk assessment. Acta Obstet Gynecol Scand. 2000 Jun;79(6):496-501. Abstract

36. Rasmussen S, Irgens LM, Albrechtsen S, et al. Women with a history of placental abruption: when in a subsequent pregnancy should special surveillance for a recurrent placental abruption be initiated? Acta Obstet Gynecol Scand. 2001 Aug;80(8):708-12. Abstract

37. Toivonen S, Heinonen S, Anttila M, et al. Obstetric prognosis after placental abruption. Fetal Diagn Ther. 2004 Jul-Aug;19(4):336-41. Abstract

38. Ruiter L, Ravelli AC, de Graaf IM, et al. Incidence and recurrence rate of placental abruption: a longitudinal linked national cohort study in the Netherlands. Am J Obstet Gynecol. 2015 Oct;213(4):573.e1-8. Abstract

39. Salihu HM, Bekan B, Aliyu MH, et al. Perinatal mortality associated with abruptio placenta in singletons and multiples. Am J Obstet Gynecol. 2005 Jul;193(1):198-203. Abstract

40. Sheiner E, Bashiri A, Levy A, et al. Obstetric characteristics and perinatal outcome of pregnancies with uterine leiomyomas. J Reprod Med. 2004 Mar;49(3):182-6. Abstract

41. Prochazka M, Lubusky M, Slavik L, et al. Frequency of selected thrombophilias in women with placental abruption. Aust N Z J Obstet Gynaecol. 2007 Aug;47(4):297-301. Abstract

42. Facchinetti F. Factor V Leiden in pregnancies complicated by placental abruption. BJOG. 2004 Jan;111(1):93. Abstract

43. Kinzler WL, Prasad V, Ananth CV, et al. The effect of maternal thrombophilia on placental abruption: Histologic correlates. J Matern Fetal Neonatal Med. 2009 Mar;22(3):243-8. Abstract

44. Jaaskelainen E, Keski-Nisula L, Toivonen S, et al. MTHFR C677T polymorphism is not associated with placental abruption or preeclampsia in Finnish women. Hypertens Pregnancy. 2006;25(2):73-80. Abstract

45. Dizon-Townson D, Miller C, Sibai B, et al. The relationship of the factor V Leiden mutation and pregnancy outcomes for mother and fetus. Obstet Gynecol. 2005 Sep;106(3):517-24. Abstract

46. American College of Radiology. ACR appropriateness criteria: second and third trimester bleeding. 2020 [internet publication].Full text

47. Notelovitz M, Bottoms SF, Dase DF, et al. Painless abruptio placentae. Obstet Gynecol. 1979 Feb;53(2):270-2. Abstract

48. Ananth CV, Berkowitz GS, Savitz DA, et al. Placental abruption and adverse perinatal outcomes. JAMA. 1999 Nov 3;282(17):1646-51.Full text  Abstract

49. Usui R, Matsubara S, Ohkuchi A, et al. Fetal heart rate pattern reflecting the severity of placental abruption. Arch Gynecol Obstet. 2008 Mar;277(3):249-53. Abstract

50. Visser GHA, Thommesen T, Di Renzo GC, et al. FIGO/ICM guidelines for preventing Rhesus disease: a call to action. Int J Gynaecol Obstet. 2021 Feb;152(2):144-7.Full text  Abstract

51. Atkinson A, Santolaya-Forgas J, Matta P, et al. The sensitivity of the Kleihauer-Betke test for placental abruption. J Obstet Gynaecol. 2015 Feb;35(2):139-41. Abstract

52. Emery CL, Morway LF, Chung-Park M, et al. The Kleihauer-Betke test. Clinical utility, indication, and correlation in patients with placental abruption and cocaine use. Arch Pathol Lab Med. 1995 Nov;119(11):1032-7. Abstract

53. Committee on Practice Bulletins—Obstetrics and the American Institute of Ultrasound in Medicine. Practice Bulletin No. 175: Ultrasound in Pregnancy. Obstet Gynecol. 2016 Dec;128(6):e241-56. Abstract

54. Kikutani M, Ishihara K, Araki T. Value of ultrasonography in the diagnosis of placental abruption. J Nippon Med Sch. 2003 Jun;70(3):227-33.Full text  Abstract

55. Yeo L, Ananth C, Vintzileos A. Placental abruption. In: Sciarra J, ed. Gynecology and obstetrics. Hagerstown, MD: Lippincott, Williams & Wilkins; 2004.

56. Glantz C, Purnell L. Clinical utility of sonography in the diagnosis and treatment of placental abruption. J Ultrasound Med. 2002 Aug;21(8):837-40. Abstract

57. Shinde GR, Vaswani BP, Patange RP, et al. Diagnostic performance of ultrasonography for detection of abruption and its clinical correlation and maternal and foetal outcome. J Clin Diagn Res. 2016 Aug;10(8):QC04-7.Full text  Abstract

58. Dhanraj D, Lambers D. The incidences of positive Kleihauer-Betke test in low-risk pregnancies and maternal trauma patients. Am J Obstet Gynecol. 2004 May;190(5):1461-3. Abstract

59. American College of Obstetricians and Gynecologists. Ultrasound in pregnancy. Dec 2016 [internet publication].Full text

60. Gayet-Ageron A, Prieto-Merino D, Ker K, et al. Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients. Lancet. 2018 Jan 13;391(10116):125-32.Full text  Abstract

61. Society of Obstetricians and Gynaecologists of Canada. Guidelines for the Management of a Pregnant Trauma Patient. Jun 2015 [internet publication].Full text

62. Society for Maternal-Fetal Medicine (SMFM), Gyamfi-Bannerman C. Society for Maternal-Fetal Medicine (SMFM) Consult Series #44: Management of bleeding in the late preterm period. Am J Obstet Gynecol. 2018 Jan;218(1):B2-8.Full text  Abstract

63. Kayani SI, Walkinshaw SA, Preston C. Pregnancy outcome in severe placental abruption. BJOG. 2003 Jul;110(7):679-83. Abstract

64. American College of Obstetricians and Gynecologists. Antenatal Corticosteroid Therapy for Fetal Maturation. Aug 2017 [internet publication].Full text

65. Saller DN Jr, Nagey DA, Pupkin MJ, et al. Tocolysis in the management of third trimester bleeding. J Perinatol. 1990 Jun;10(2):125-8. Abstract

66. Towers CV, Pircon RA, Heppard M. Is tocolysis safe in the management of third-trimester bleeding? Am J Obstet Gynecol. 1990 Jun;10(2):125-8. Abstract

67. Henderson CE, Goldman B, Divon MY. Ritodrine therapy in the presence of chronic abruptio placentae. Obstet Gynecol. 1992 Sep;80(3 Pt 2):510-2. Abstract

68. US Food and Drug Administration. FDA drug safety communication: FDA recommends against prolonged use of magnesium sulfate to stop pre-term labor due to bone changes in exposed babies. May 2013 [internet publication].Full text

69. Medicines and Healthcare products Regulatory Agency. Magnesium sulfate: risk of skeletal adverse effects in the neonate following prolonged or repeated use in pregnancy. 2019 May;12(10):3.Full text

70. Ananth CV, Wilcox AJ. Placental abruption and perinatal mortality in the United States. Am J Epidemiol. 2001 Feb 15;153(4):332-7.Full text  Abstract

71. Ananth CV, Vintzileos AM. Medically indicated preterm birth: recognizing the importance of the problem. Clin Perinatol. 2008 Mar;35(1):53-67. Abstract

72. Ananth CV, Vintzileos AM. Maternal-fetal conditions necessitating a medical intervention resulting in preterm birth. Am J Obstet Gynecol. 2006 Dec;195(6):1557-63. Abstract

73. Gibbs JM, Weindling AM. Neonatal intracranial lesions following placental abruption. Eur J Pediatr. 1994 Mar;153(3):195-7. Abstract

74. Pitaphrom A, Sukcharoen N. Pregnancy outcomes in placental abruption. J Med Assoc Thai. 2006 Oct;89(10):1572-8. Abstract

75. Rasmussen S, Irgens LM, Dalaker K. The effect on the likelihood of further pregnancy of placental abruption and the rate of its recurrence. Br J Obstet Gynaecol. 1997 Nov;104(11):1292-5. Abstract

76. Furuhashi M, Kurauchi O, Suganuma N. Pregnancy following placental abruption. Arch Gynecol Obstet. 2002 Nov;267(1):11-3. Abstract

77. Ananth CV, Patrick HS, Ananth S, et al. Maternal cardiovascular and cerebrovascular health after placental abruption: a systematic review and meta-analysis (CHAP-SR). Am J Epidemiol. 2021 Dec 1;190(12):2718-29.Full text  Abstract

78. Lockwood CJ, Toti P, Arcuri F, et al. Mechanisms of abruption-induced premature rupture of the fetal membranes: thrombin-enhanced interleukin-8 expression in term decidua. Am J Pathol. 2005 Nov;167(5):1443-9. Abstract

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