Oropharyngeal cancer

References

Key articles

National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: head and neck cancers [internet publication].Full text

Amin MB, Edge SB, Greene FL, et al, eds. AJCC cancer staging manual. 8th ed. New York, NY: Springer International Publishing, 2017.

Reference articles

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2. National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: head and neck cancers [internet publication].Full text

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13. Turati F, Garavello W, Tramacere I, et al. A meta-analysis of alcohol drinking and oral and pharyngeal cancers: results from subgroup analyses. Alcohol and Alcoholism. 2013 Jan-Feb;48(1):107-18.Full text  Abstract

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16. D'Souza G, Kreimer AR, Viscidi R, et al. Case-control study of human papillomavirus and oropharyngeal cancer. N Engl J Med. 2007 May 10;356(19):1944-56.Full text  Abstract

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20. Hashibe M, Brennan P, Strange RC, et al. Meta- and pooled analyses of GSTM1, GSTT1, GSTP1, and CYP1A1 genotypes and risk of head and neck cancer. Cancer Epidemiol Biomarkers Prev. 2003 Dec;12(12):1509-17.Full text  Abstract

21. Wang X, Wang HK, McCoy JP, et al. Oncogenic HPV infection interrupts the expression of tumor-suppressive miR-34a through viral oncoprotein E6. RNA. 2009 Apr;15(4):637-47.Full text  Abstract

22. Boffetta P, Hecht S, Gray N, et al. Smokeless tobacco and cancer. Lancet Oncol. 2008 Jul;9(7):667-75. Abstract

23. Chen YJ, Chang JT, Liao CT, et al. Head and neck cancer in the betel quid chewing area: recent advances in molecular carcinogenesis. Cancer Sci. 2008 Aug;99(8):1507-14.Full text  Abstract

24. Chaturvedi AK, Engels EA, Anderson WF, et al. Incidence trends for human papillomavirus-related and -unrelated oral squamous cell carcinomas in the United States. J Clin Oncol. 2008 Feb 1;26(4):612-9.Full text  Abstract

25. Hammarstedt L, Dahlstrand H, Lindquist D, et al. The incidence of tonsillar cancer in Sweden is increasing. Acta Otolaryngol. 2007 Sep;127(9):988-92. Abstract

26. Lee JJ, Jeng JH, Wang HM, et al. Univariate and multivariate analysis of prognostic significance of betel quid chewing in squamous cell carcinoma of buccal mucosa in Taiwan. J Surg Oncol. 2005 Jul 1;91(1):41-7. Abstract

27. Meites E, Szilagyi PG, Chesson HW, et al. Human papillomavirus vaccination for adults: updated recommendations of the Advisory Committee on Immunization Practices. MMWR Morb Mortal Wkly Rep. 2019 Aug 16;68(32):698-702.Full text  Abstract

28. Epstein JB, Gorsky M, Cabay RJ, et al. Screening for and diagnosis of oral premalignant lesions and oropharyngeal squamous cell carcinoma: role of primary care physicians. Can Fam Physician. 2008 Jun;54(6):870-5.Full text  Abstract

29. Nguyen NP, Vos P, Moltz CC, et al. Analysis of the factors influencing dysphagia severity upon diagnosis of head and neck cancer. Br J Radiol. 2008 Sep;81(969):706-10. Abstract

30. Nguyen NP, Vos P, Lee H, et al. Impact of tumor board recommendations on treatment outcome for locally advanced head and neck cancer. Oncology. 2008;75(3-4):186-91. Abstract

31. Nguyen NP, North D, Smith HJ, et al. Safety and effectiveness of prophylactic gastrostomy tubes for head and neck cancer patients undergoing chemoradiation. Surg Oncol. 2006 Dec;15(4):199-203. Abstract

32. Amin MB, Edge SB, Greene FL, et al, eds. AJCC cancer staging manual. 8th ed. New York, NY: Springer International Publishing, 2017.

33. Lenz M, Greess H, Baum U, et al. Oropharynx, oral cavity, floor of the mouth: CT or MRI. Eur J Radiol. 2000 Mar;33(3):203-15. Abstract

34. Zima AJ, Wesolowski JR, Ibrahim N, et al. Magnetic resonance imaging of oropharyngeal cancer. Top Magn Reson Imaging. 2007 Aug;18(4):237-42. Abstract

35. Wong RJ. Current status of FDG-PET for head and neck cancer. J Surg Oncol. 2008 Jun 15;97(8):649-52. Abstract

36. Branstetter BF 4th, Blodgett TM, Zimmer LA, et al. Head and neck malignancy: is PET/CT more accurate than PET or CT alone? Radiology. 2005 May;235(2):580-6. Abstract

37. Kim SJ, Pak K, Kim K. Diagnostic accuracy of F-18 FDG PET or PET/CT for detection of lymph node metastasis in clinically node negative head and neck cancer patients; A systematic review and meta-analysis. Am J Otolaryngol. 2019 Mar - Apr;40(2):297-305. Abstract

38. Heron DE, Andrade RS, Beriwal S, et al. PET-CT in radiation oncology: the impact on diagnosis, treatment planning, and assessment of treatment response. Am J Clin Oncol. 2008 Aug;31(4):352-62. Abstract

39. Balm AJ, van Velthuysen ML, Hoebers FJ, et al. Diagnosis and treatment of a neck node swelling suspicious for a malignancy: an algorithmic approach. Int J Surg Oncol. 2010 May 30;2010:581540.Full text  Abstract

40. van den Brekel MW, Casteljins JA, Stel HV, et al. Modern imaging techniques and ultrasound-guided aspiration cytology for the assessment of neck node metastases: a prospective comparative study. Eur Arch Otorhinolaryngol. 1993;250(1):11-7. Abstract

41. Dabirmoghaddam P, Sharifkashany S, Mashali L. Ultrasound-guided fine needle aspiration cytology in the assessment of cervical metastasis in patients undergoing elective neck dissection. Iran J Radiol. 2014 Aug;11(3):e7928. Abstract

42. Lewis JS Jr, Beadle B, Bishop JA, et al. Human papillomavirus testing in head and neck carcinomas: guideline from the college of American pathologists. Arch Pathol Lab Med. 2018 May;142(5):559-97.Full text  Abstract

43. Guardiola E, Pivot X, Dassonville O, et al. Is routine triple endoscopy for head and neck carcinoma patients necessary in light of a negative chest computed tomography scan? Cancer. 2004 Nov 1;101(9):2028-33.Full text  Abstract

44. Hujala K, Sipilä J, Grenman R. Panendoscopy and synchronous second primary tumors in head and neck cancer patients. Eur Arch Otorhinolaryngol. 2005 Jan;262(1):17-20. Abstract

45. Guardiola E, Chaigneau L, Villanueva C, et al. Is there still a role for triple endoscopy as part of staging for head and neck cancer? Curr Opin Otolaryngol Head Neck Surg. 2006 Apr;14(2):85-8. Abstract

46. Erdi YE. Limits of tumor detectability in nuclear medicine and PET. Mol Imaging Radionucl Ther. 2012 Apr 1;21(1):23-8.Full text  Abstract

47. Miller FR, Karnad AB, Eng T, et al. Management of the unknown primary carcinoma: long-term follow-up on a negative PET scan and negative panendoscopy. Head Neck. 2008 Jan;30(1):28-34.Full text  Abstract

48. Pitchers M, Martin C. Delay in referral of oropharyngeal squamous cell carcinoma to secondary care correlates with a more advanced stage at presentation, and is associated with poorer survival. Br J Cancer. 2006 Apr 10;94(7):955-8.Full text  Abstract

49. Roosli C, Tschudi DC, Studer G, et al. Outcome of patients after treatment for a squamous cell carcinoma of the oropharynx. Laryngoscope. 2009 Mar;119(3):534-40. Abstract

50. Koivunen P, Rantala N, Hyrynkangas, et al. The impact of patient and professional diagnostic delays on survival in pharyngeal cancer. Cancer. 2001 Dec 1;92(11):2885-91.Full text  Abstract

51. Tromp DM, Brouha XD, Hordijk GJ, et al. Patient and tumour factors associated with advanced carcinomas of the head and neck. Oral Oncol. 2005 Mar;41(3):313-9. Abstract

52. van Bokhorst-de van der Schueren MA, van Leeuwen PA, Sauerwein HP, et al. Assessment of malnutrition parameters in head and neck cancer and their relation to postoperative complications. Head Neck. 1997 Aug;19(5):419-25. Abstract

53. Ho T, Zahurak M, Koch WM. Prognostic significance of presentation-to-diagnosis interval in patients with oropharyngeal carcinoma. Arch Otolaryngol Head Neck Surg. 2004 Jan;130(1):45-51.Full text  Abstract

54. Ichimura K, Tanaka T. Trismus in patients with malignant tumours in the head and neck. J Laryngol Otol. 1993 Nov;107(11):1017-20. Abstract

55. Nahmias C, Lemmens C, Faul D, et al. Does reducing CT artifacts from dental implants influence the PET interpretation in PET/CT studies of oral cancer and head and neck cancer? J Nucl Med. 2008 Jul;49(7):1047-52.Full text  Abstract

56. Gourin CG, Watts T, Willams HT, et al. Identification of distant metastases with PET-CT in patients with suspected recurrent head and neck cancer. Laryngoscope. 2009 Apr;119(4):703-6. Abstract

57. Pantvaidya GH, Agarwal JP, Deshpande MS, et al. PET-CT in recurrent head neck cancers: a study to evaluate impact on patient management. J Surg Oncol. 2009 Oct 1;100(5):401-3. Abstract

58. Abgral R, Querellou S, Potard G, et al. Does 18-FDG PET/CT improve the detection of posttreatment recurrence of head and neck squamous cell carcinoma in patients negative for disease on clinical follow-up? J Nucl Med. 2009 Jan;50(1):24-9. Abstract

59. Connell CA, Corry J, Milner AD, et al. Clinical impact of, and prognostic stratification by, F-18 FDG PET/CT in head and neck mucosal squamous cell carcinoma. Head Neck. 2007 Nov;29(11):986-95. Abstract

60. Oken MM, Creech RH, Tormey DC, et al. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol. 1982 Dec;5(6):649-55. Abstract

61. Epstein JB, Silverman S Jr., Epstein JD, et al. Analysis of oral lesion biopsies identified and evaluated by visual examination, chemoluminescence and toluidine blue. Oral Oncol. 2008 Jun;44(6):538-44. [Erratum in: Oral Oncol. 2008 Jun;44(6):615.] Abstract

62. NIH National Cancer Institute. Oral cavity, pharyngeal, and laryngeal cancer screening (PDQ®) - health professional version. May 2023 [internet publication].Full text

63. American College of Radiology. ACR appropriateness criteria: staging and post-therapy assessment of head and neck cancer​. 2023 [internet publication].Full text

64. Machiels JP, René Leemans C, Golusinski W, et al. Squamous cell carcinoma of the oral cavity, larynx, oropharynx and hypopharynx: EHNS-ESMO-ESTRO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2020 Nov;31(11):1462-75.Full text  Abstract

65. Cosmidis A, Rame JP, Dassonville O, et al; Groupement d'Etudes des Tumeurs de la Tête et du Cou (GETTEC). T1-T2 N0 oropharyngeal cancers treated with surgery alone: a GETTEC study. Eur Arch Otorhinolaryngol. 2004 May;261(5):276-81. Abstract

66. Parsons JT, Mendenhall WM, Stringer SP, et al. Squamous cell carcinoma of the oropharynx: surgery, radiotherapy, or both. Cancer. 2002 Jun 1;94(11):2967-80.Full text  Abstract

67. Soo KC, Tan EH, Wee J, et al. Surgery and adjuvant radiotherapy vs concurrent chemoradiotherapy in stage III/IV nonmetastatic squamous cell head and neck cancer: a randomised comparison. Br J Cancer. 2005 Aug 8;93(3):279-86.Full text  Abstract

68. Rieger J, Dickson N, Lemire R, et al. Social perception of speech in individuals with oropharyngeal reconstruction. J Psychosoc Oncol. 2006;24(4):33-51. Abstract

69. Rogers SN, Miller RD, Ali K, et al. Patients' perceived health status following primary surgery for oral and oropharyngeal cancer. Int J Oral Maxillofac Surg. 2006 Oct;35(10):913-9. Abstract

70. Bonner JA, Harari PM, Giralt J, et al. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med. 2006 Feb 9;354(6):567-78.Full text  Abstract

71. Xu Q, Huang S, Yang K. Combination immunochemotherapy for recurrent or metastatic head and neck squamous cell carcinoma: a systematic review and meta-analysis. BMJ Open. 2023 Jun 13;13(6):e069047.Full text  Abstract

72. Vermorken JB, Mesia R, Rivera F, et al. Platinum-based chemotherapy plus cetuximab in head and neck cancer. N Engl J Med. 2008 Sep 11;359(11):1116-27.Full text  Abstract

73. Adelstein DJ, Ismaila N, Ku JA, et al. Role of treatment deintensification in the management of p16+ oropharyngeal cancer: ASCO provisional clinical opinion. J Clin Oncol. 2019 Jun 20;37(18):1578-89.Full text  Abstract

74. Nichols AC, Faquin WC, Westra WH, et al. HPV-16 infection predicts treatment outcome in oropharyngeal squamous cell carcinoma. Otolaryngol Head Neck Surg. 2009 Feb;140(2):228-34. Abstract

75. Lassen P, Eriksen JG, Hamilton-Dutoit S, et al. Effect of HPV-associated p16INK4A expression on response to radiotherapy and survival in squamous cell carcinoma of the head and neck. J Clin Oncol. 2009 Apr 20;27(12):1992-8. Abstract

76. Fakhry C, Westra W, Li S, et al. Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial. J Natl Cancer Inst. 2008 Feb 20;100(4):261-9.Full text  Abstract

77. Parikh A, Lin D, Goyal N. Clinical outcomes of transoral robotic-assisted surgery for the management of head and neck cancer. Robot Surg. 2023 Feb 20;2(2015):95-105.Full text

78. Denittis AS, Machtay M, Rosenthal DI, et al. Advanced oropharyngeal cancer treated with surgery and radiotherapy: oncologic outcome and functional assessment. Am J Otolaryngol. 2001 Sep-Oct;22(5):329-35. Abstract

79. Lim YC, Hong HJ, Baek SJ, et al. Combined surgery and postoperative radiotherapy for oropharyngeal squamous cell carcinoma in Korea: analysis of 110 cases. Int J Oral Maxillofac Surg. 2008 Dec;37(12):1099-105. Abstract

80. Nguyen NP, Vos P, Smith HJ, et al. Concurrent chemoradiation for locally advanced oropharyngeal cancer. Am J Otolaryngol. 2007 Jan-Feb;28(1):3-8. Abstract

81. Adelstein DJ, Saxton JP, Lavertu P, et al. A phase III randomized trial comparing concurrent chemotherapy and radiotherapy with radiotherapy alone in resectable stage III and IV squamous cell head and neck cancer: preliminary results. Head Neck. 1997 Oct;19(7):567-75. Abstract

82. Blanchard P, Baujat B, Holostenco V, et al. Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): a comprehensive analysis by tumour site. Radiother Oncol. 2011 Jul;100(1):33-40. Abstract

83. Budach V, Stuschke M, Budach W, et al. Hyperfractionated accelerated chemoradiation with concurrent fluorouracil-mitomycin is more effective than dose-escalated hyperfractionated accelerated radiation therapy alone in locally advanced head and neck cancer: final results of the Radiotherapy Cooperative Clinical Trials Group of the German Cancer Society 95-06 Prospective Randomized Trial. J Clin Oncol. 2005 Feb 20;23(6):1125-35.Full text  Abstract

84. Tao Y, Auperin A, Sire C, et al. Improved outcome by adding concurrent chemotherapy to cetuximab and radiotherapy for locally advanced head and neck carcinomas: results of the GORTEC 2007-01 phase III randomized trial. J Clin Oncol. 2018 Nov;36(31):3084-90. Abstract

85. Gillison ML, Trotti AM, Harris J, et al. Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal cancer (NRG Oncology RTOG 1016): a randomised, multicentre, non-inferiority trial. Lancet. 2018 Nov 15;393(10166):40-50. Abstract

86. Mehanna H, Robinson M, Hartley A, et al. Radiotherapy plus cisplatin or cetuximab in low-risk human papillomavirus-positive oropharyngeal cancer (De-ESCALaTE HPV): an open-label randomised controlled phase 3 trial. Lancet. 2018 Nov 15;393(10166):51-60.Full text  Abstract

87. Bensadoun RJ, Benezery K, Dassonville O, et al. French multicenter phase III randomized study testing concurrent twice-a-day radiotherapy and cisplatin/5-fluorouracil chemotherapy (BiRCF) in unresectable pharyngeal carcinoma: results at 2 years (FNCLCC-GORTEC). Int J Radiat Oncol Biol Phys. 2006 Mar 15;64(4):983-94. Abstract

88. Staar S, Rudat V, Stuetzer H, et al. Intensified hyperfractionated accelerated radiotherapy limits the additional benefit of simultaneous chemotherapy: results of a multicentric randomized German trial in advanced head-and-neck cancer. Int J Radiat Oncol Biol Phys. 2001 Aug 1;50(5):1161-71. [Erratum in: Int J Radiat Oncol Biol Phys 2001 Oct 1;51(2):569.] Abstract

89. Semrau R, Mueller RP, Stuetzer H, et al. Efficacy of intensified hyperfractionated and accelerated radiotherapy and concurrent chemotherapy with carboplatin and 5-fluorouracil: updated results of a randomized multicentric trial in advanced head-and-neck cancer. Int J Radiat Oncol Biol Phys. 2006 Apr 1;64(5):1308-16. Abstract

90. Denis F, Garaud P, Bardet E, et al. Final results of the 94-01 French Head and Neck Oncology and Radiotherapy Group randomized trial comparing radiotherapy alone with concomitant chemoradiotherapy in advanced-stage oropharynx carcinoma. J Clin Oncol. 2004 Jan 1;22(1):69-76.Full text  Abstract

91. Calais G, Alfonsi M, Bardet E, et al. Randomized trial of radiation therapy versus concomitant chemotherapy and radiation therapy for advanced-stage oropharynx carcinoma. J Natl Cancer Inst. 1999 Dec 15;91(24):2081-6.Full text  Abstract

92. Brizel DM, Albers ME, Fisher SR, et al. Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer. N Engl J Med. 1998 Jun 18;338(25):1798-804.Full text  Abstract

93. Pignon JP, le Maitre A, Maillard E, et al; MACH-NC Collaborative Group. Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patients. Radiother Oncol. 2009 Jul;92(1):4-14. Abstract

94. Posner MR, Hershock DM, Blajman CR, et al; TAX 324 Study Group. Cisplatin and fluorouracil alone or with docetaxel in head and neck cancer. N Engl J Med. 2007 Oct 25;357(17):1705-15.Full text  Abstract

95. Adelstein DJ, Li Y, Adams GL, et al. An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer. J Clin Oncol. 2003 Jan 1;21(1):92-8. Abstract

96. Blanchard P, Bourhis J, Lacas B, et al; Meta-Analysis of Chemotherapy in Head and Neck Cancer, Induction Project, Collaborative Group. Taxane-cisplatin-fluorouracil as induction chemotherapy in locally advanced head and neck cancers: an individual patient data meta-analysis of the meta-analysis of chemotherapy in head and neck cancer group. J Clin Oncol. 2013 Aug 10;31(23):2854-60.Full text  Abstract

97. Martins RG, Parvathaneni U, Bauman JE, et al. Cisplatin and radiotherapy with or without erlotinib in locally advanced squamous cell carcinoma of the head and neck: a randomized phase II trial. J Clin Oncol. 2013 Apr 10;31(11):1415-21.Full text  Abstract

98. Mesia R, Henke M, Fortin A, et al. Chemoradiotherapy with or without panitumumab in patients with unresected, locally advanced squamous-cell carcinoma of the head and neck (CONCERT-1): a randomised, controlled, open-label phase 2 trial. Lancet Oncol. 2015 Feb;16(2):208-20. Abstract

99. Burtness B, Goldwasser MA, Flood W, et al. A phase III randomized trial of cisplatin plus placebo compared with cisplatin plus cetuximab in metastatic/recurrent head and neck cancer: an Eastern Cooperative Oncology Group study. J Clin Oncol. 2005 Dec 1;23(34):8646-54. [Erratum in: J Clin Oncol. 2006 Feb 1;24(4):724.]Full text  Abstract

100. Tol J, Koopman M, Cats A, et al. Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer. N Engl J Med. 2009 Feb 5;360(6):563-72.Full text  Abstract

101. Bumpous JM. Surgical salvage of cancer of the oropharynx after chemoradiation. Curr Oncol Rep. 2009 Mar;11(2):151-5. Abstract

102. Watkins JM, Shirai KS, Wahlquist AE, et al. Toxicity and survival outcomes of hyperfractionated split-course reirradiation and daily concurrent chemotherapy in locoregionally recurrent, previously irradiated head and neck cancers. Head Neck. 2009 Apr;31(4):493-502. Abstract

103. Seiwert TY, Burtness B, Mehra R, et al. Safety and clinical activity of pembrolizumab for treatment of recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-012): an open-label, multicentre, phase 1b trial. Lancet Oncol. 2016 May 27;17(7):956-65. Abstract

104. Chow LQ, Haddad R, Gupta S, et al. Antitumor activity of pembrolizumab in biomarker-unselected patients with recurrent and/or metastatic head and neck squamous cell carcinoma: results from the phase Ib KEYNOTE-012 expansion cohort. J Clin Oncol. 2016 Sep 30;34(32):3838-45.Full text  Abstract

105. Burtness B, Harrington KJ, Greil R, et al. Pembrolizumab alone or with chemotherapy versus cetuximab with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-048): a randomised, open-label, phase 3 study. Lancet. 2019 Nov 23;394(10212):1915-28. Abstract

106. Ferris RL, Blumenschein G Jr, Fayette J, et al. Nivolumab for recurrent squamous-cell carcinoma of the head and neck. N Engl J Med. 2016 Nov 10;375(19):1856-67.Full text  Abstract

107. Harrington KJ, Ferris RL, Blumenschein G Jr, et al. Nivolumab versus standard, single-agent therapy of investigator's choice in recurrent or metastatic squamous cell carcinoma of the head and neck (CheckMate 141): health-related quality-of-life results from a randomised, phase 3 trial. Lancet Oncol. 2017 Aug;18(8):1104-15. Abstract

108. Brock PR, Maibach R, Childs M, et al. Sodium thiosulfate for protection from cisplatin-induced hearing loss. N Engl J Med. 2018 Jun 21;378(25):2376-85.Full text  Abstract

109. Meluch AA, Spigel D, Burris HA, et al. Combined modality therapy with radiation therapy (RT), chemotherapy, bevacizumab, and erlotinib in the treatment of patients (pts) with locally advanced squamous carcinoma of the head and neck. J Clin Oncol. 2009 May 20;27(15_suppl):6012.

110. Mercke C, Wickart-Johansson G, Sjodin H, et al. Upfront chemotherapy and accelerated radiotherapy with EGFR inhibition for locally advanced inoperable head and neck cancer. J Clin Oncol. 2009 May 20;27(15_suppl):6040.

111. Vermorken JB, Stöhlmacher-Williams J, Davidenko I, et al; SPECTRUM investigators. Cisplatin and fluorouracil with or without panitumumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck (SPECTRUM): an open-label phase 3 randomised trial. Lancet Oncol. 2013 Jul;14(8):697-710. Abstract

112. Pang E, Delic NC, Hong A, et al. Radiosensitization of oropharyngeal squamous cell carcinoma cells by human papillomavirus 16 oncoprotein E6∗I. Int J Radiat Oncol Biol Phys. 2011 Mar 1;79(3):860-5. Abstract

113. Young R, Rischin D, Fisher R, et al. Relationship between epidermal growth factor receptor status, p16(INK4A), and outcome in head and neck squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev. 2011 Jun;20(6):1230-7. Abstract

114. Nguyen NP, Ceizyk M, Vos P, et al. Feasibility of tomotherapy-based image-guided radiotherapy for locally advanced oropharyngeal cancer. PLoS One. 2013;8(3):e60268.Full text  Abstract

115. Kuhn MA, Gillespie MB, Ishman SL, et al. Expert consensus statement: management of dysphagia in head and neck cancer patients. Otolaryngol Head Neck Surg. 2023 Apr;168(4):571-92.Full text  Abstract

116. Yilmaz E, Ismaila N, Bauman JE, et al. Immunotherapy and biomarker testing in recurrent and metastatic head and neck cancers: ASCO guideline. J Clin Oncol. 2023 Feb 10;41(5):1132-46.Full text  Abstract

117. Koyfman SA, Ismaila N, Crook D, et al. Management of the neck in squamous cell carcinoma of the oral cavity and oropharynx: ASCO clinical practice guideline. J Clin Oncol. 2019 Jul 10;37(20):1753-74.Full text  Abstract

118. Quon H, Vapiwala N, Forastiere A, et al. Radiation therapy for oropharyngeal squamous cell carcinoma: American Society of Clinical Oncology endorsement of the American Society for Radiation Oncology evidence-based clinical practice guideline. J Clin Oncol. 2017 Oct 24;35(36):4078-90.Full text  Abstract

119. Beitler JJ, Quon H, Jones CU, et al; Expert Panel on Radiation Oncology - Head and Neck. ACR appropriateness criteria® locoregional therapy for resectable oropharyngeal squamous cell carcinomas. Head Neck. 2016 Jun 22;38(9):1299-309. Abstract

120. Rischin D, Young RJ, Fisher R, et al. Prognostic significance of p16INK4A and human papillomavirus in patients with oropharyngeal cancer treated on TROG 02.02 phase III trial. J Clin Oncol. 2010 Sep 20;28(27):4142-8. Abstract

121. Ang KK, Harris J, Wheeler R, et al. Human papillomavirus and survival of patients with oropharyngeal cancer. N Engl J Med. 2010 Jul 1;363(1):24-35.Full text  Abstract

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