Hemorrhagic stroke

References

Key articles

Greenberg SM, Ziai WC, Cordonnier C, et al. 2022 Guideline for the management of patients with spontaneous intracerebral hemorrhage: a guideline from the American Heart Association/American Stroke Association. Stroke. 2022 Jul;53(7):e282-361.Full text  Abstract

Derdeyn CP, Zipfel GJ, Albuquerque FC, et al. Management of brain arteriovenous malformations: a scientific statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2017 Aug;48(8):e200-24.Full text  Abstract

Kleindorfer DO, Towfighi A, Chaturvedi S, et al. 2021 guideline for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline from the American Heart Association/American Stroke Association. Stroke. 2021 Jul;52(7):e364-e467.Full text  Abstract

Steiner T, Al-Shahi Salman R, Beer R, et al. European Stroke Organisation (ESO) guidelines for the management of spontaneous intracerebral hemorrhage. Int J Stroke. 2014 Oct;9(7):840-55.Full text  Abstract

Reference articles

1. Qureshi AI, Tuhrim S, Broderick JP, et al. Spontaneous intracerebral hemorrhage. N Engl J Med. 2001 May 10;344(19):1450-60. Abstract

2. Smith EE, Rosand J, Greenberg SM. Hemorrhagic stroke. Neuroimaging Clin N Am. 2005 May;15(2):259-72. Abstract

3. Rathore SS, Hinn AR, Cooper LS, et al. Characterization of incident stroke signs and symptoms: findings from the atherosclerosis risk in communities study. Stroke. 2002 Nov;33(11):2718-21.Full text  Abstract

4. GBD 2016 Stroke Collaborators. Global, regional, and national burden of stroke, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol. 2019 May;18(5):439-58.Full text  Abstract

5. Tsao CW, Aday AW, Almarzooq ZI, et al. Heart disease and stroke statistics-2022 update: a report from the American Heart Association. Circulation. 2022 Feb 22;145(8):e153-639.Full text  Abstract

6. GBD 2019 Diseases and Injuries Collaborators. Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020 Oct 17;396(10258):1204-22.Full text  Abstract

7. GBD 2016 Lifetime Risk of Stroke Collaborators, Feigin VL, Nguyen G, et al. Global, regional, and country-specific lifetime risks of stroke, 1990 and 2016. N Engl J Med. 2018 Dec 20;379(25):2429-37.Full text  Abstract

8. Greenberg SM, Ziai WC, Cordonnier C, et al. 2022 Guideline for the management of patients with spontaneous intracerebral hemorrhage: a guideline from the American Heart Association/American Stroke Association. Stroke. 2022 Jul;53(7):e282-361.Full text  Abstract

9. Appelros P, Stegmayr B, Terént A. Sex differences in stroke epidemiology: a systematic review. Stroke. 2009 Apr;40(4):1082-90.Full text  Abstract

10. Block F, Dafotakis M. Cerebral amyloid angiopathy in stroke medicine. Dtsch Arztebl Int. 2017 Jan 20;114(3):37-42.Full text  Abstract

11. Smith EE, Greenberg SM. Clinical diagnosis of cerebral amyloid angiopathy: validation of the Boston criteria. Curr Atheroscler Rep. 2003 Jul;5(4):260-6. Abstract

12. Zhang-Nunes SX, Maat-Schieman ML, van Duinen SG, et al. The cerebral beta-amyloid angiopathies: hereditary and sporadic. Brain Pathol. 2006 Jan;16(1):30-9. Abstract

13. Wang DN, Hou XW, Yang BW, et al. Quantity of cerebral microbleeds, antiplatelet therapy, and intracerebral hemorrhage outcomes: a systematic review and meta-analysis. J Stroke Cerebrovasc Dis. 2015 Dec;24(12):2728-37. Abstract

14. Derdeyn CP, Zipfel GJ, Albuquerque FC, et al. Management of brain arteriovenous malformations: a scientific statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2017 Aug;48(8):e200-24.Full text  Abstract

15. Fisher CM. Pathological observations in hypertensive cerebral hemorrhage. J Neuropathol Exp Neurol. 1971 Jul;30(3):536-50. Abstract

16. Mayer SA, Brun NC, Begtrup K, et al. Efficacy and safety of recombinant activated factor VII for acute intracerebral hemorrhage. N Engl J Med. 2008 May 15;358(20):2127-37. Abstract

17. Al-Shahi Salman R, Frantzias J, Lee RJ, et al. Absolute risk and predictors of the growth of acute spontaneous intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data. Lancet Neurol. 2018 Oct;17(10):885-94.Full text  Abstract

18. Petrovska-Cvetkovska D, Dolnenec-Baneva N, Nikodijevik D, et al. Correlative study between serum matrix metalloproteinase-9 values and neurologic deficit in acute, primary, supratentorial, intracerebral haemorrhage. Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2014;35(2):39-44.Full text  Abstract

19. Yang Q, Zhuang X, Peng F, et al. Relationship of plasma matrix metalloproteinase-9 and hematoma expansion in acute hypertensive cerebral hemorrhage. Int J Neurosci. 2016;126(3):213-8. Abstract

20. Mittal MK, LacKamp A. Intracerebral hemorrhage: perihemorrhagic edema and secondary hematoma expansion: from bench work to ongoing controversies. Front Neurol. 2016 Nov 21;7:210.Full text  Abstract

21. Hemphill JC 3rd, Bonovich DC, Besmertis L, et al. The ICH score: a simple, reliable grading scale for intracerebral hemorrhage. Stroke. 2001 Apr;32(4):891-7.Full text  Abstract

22. Kannel WB, Wolf PA, Verter J, et al. Epidemiologic assessment of the role of blood pressure in stroke. The Framingham study. JAMA. 1970 Oct 12;214(2):301-10. Abstract

23. Woo D, Sauerbeck LR, Kissela BM, et al. Genetic and environmental risk factors for intracerebral hemorrhage: preliminary results of a population-based study. Stroke. 2002 May;33(5):1190-5.Full text  Abstract

24. Tsao CW, Aday AW, Almarzooq ZI, et al. Heart disease and stroke statistics-2022 update: a report from the American Heart Association. Circulation. 2022 Feb 22;145(8):e153-e639.Full text  Abstract

25. Broderick J, Brott T, Kothari R, et al. The Greater Cincinnati/Northern Kentucky Stroke Study: preliminary first-ever and total incidence rates of stroke among blacks. Stroke. 1998 Feb;29(2):415-21.Full text  Abstract

26. Labovitz DL, Halim A, Boden-Albala B, et al. The incidence of deep and lobar intracerebral hemorrhage in whites, blacks and Hispanics. Neurology. 2005 Aug 23;65(4):518-22. Abstract

27. Flaherty ML, Woo D, Haverbusch M, et al. Racial variations in location and risk of intracerebral hemorrhage. Stroke. 2005 May;36(5):934-7.Full text  Abstract

28. Greenberg SM, Eng JA, Ning M, et al. Hemorrhage burden predicts recurrent intracerebral hemorrhage after lobar hemorrhage. Stroke. 2004 Jun;35(6):1415-20.Full text  Abstract

29. Smith EE, Gurol ME, Eng JA, et al. White matter lesions, cognition, and recurrent hemorrhage in lobar intracerebral hemorrhage. Neurology. 2004 Nov 9;63(9):1606-12. Abstract

30. O'Donnell HC, Rosand J, Knudsen KA, et al. Apolipoprotein E genotype and the risk of recurrent lobar intracerebral hemorrhage. N Engl J Med. 2000 Jan 27;342(4):240-5.Full text  Abstract

31. Gould DB, Phalan FC, van Mil SE, et al. Role of COL4A1 in small-vessel disease and hemorrhagic stroke. N Engl J Med. 2006 Apr 6;354(14):1489-96.Full text  Abstract

32. Antithrombotic Trialists' Collaboration. Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. BMJ. 2002 Jan 12;324(7329):71-86.Full text  Abstract

33. Huang WY, Saver JL, Wu YL, et al. Frequency of intracranial hemorrhage with low-dose aspirin in individuals without symptomatic cardiovascular disease: a systematic review and meta-analysis. JAMA Neurol. 2019 May 13;76(8):906-14.Full text  Abstract

34. Ruff CT, Giugliano RP, Braunwald E, et al. Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials. Lancet. 2014 Mar 15;383(9921):955-62. Abstract

35. Lappin JM, Darke S, Farrell M. Stroke and methamphetamine use in young adults: a review. J Neurol Neurosurg Psychiatry. 2017 Dec;88(12):1079-91. Abstract

36. Wojak JC, Flamm ES. Intracranial hemorrhage and cocaine use. Stroke. 1987 Jul-Aug;18(4):712-5.Full text  Abstract

37. Barnes B, Cawley CM, Barrow DL. Intracerebral hemorrhage secondary to vascular lesions. Neurosurg Clin N Am. 2002 Jul;13(3):289-97. Abstract

38. Ariesen MJ, Claus SP, Rinkel GJ, et al. Risk factors for intracerebral hemorrhage in the general population: a systematic review. Stroke. 2003 Aug;34(8):2060-5.Full text  Abstract

39. Price AJ, Wright FL, Green J, et al. Differences in risk factors for 3 types of stroke: UK prospective study and meta-analyses. Neurology. 2018 Jan 23;90(4):e298-306.Full text  Abstract

40. Ungprasert P, Matteson EL, Thongprayoon C. Nonaspirin nonsteroidal anti-inflammatory drugs and risk of hemorrhagic stroke: a systematic review and meta-analysis of observational studies. Stroke. 2016 Feb;47(2):356-64. Abstract

41. Boulanger M, Poon MT, Wild SH, et al. Association between diabetes mellitus and the occurrence and outcome of intracerebral hemorrhage. Neurology. 2016 Aug 30;87(9):870-8.Full text  Abstract

42. Saliba W, Barnett-Griness O, Gronich N, et al. Association of diabetes and glycated hemoglobin with the risk of intracerebral hemorrhage: a population-based cohort study. Diabetes Care. 2019 Apr;42(4):682-8.Full text  Abstract

43. Reynolds K, Lewis B, Nolen JD, et al. Alcohol consumption and risk of stroke: a meta-analysis. JAMA. 2003 Feb 5;289(5):579-88. Abstract

44. Cohen BA, Biller J. Hemorrhagic stroke due to cerebral vasculitis and the role of immunosuppressive therapy. Neurosurg Clin N Am. 1992 Jul;3(3):611-24. Abstract

45. Takahashi JC, Funaki T, Houkin K, et al; JAM Trial Investigators. Significance of the hemorrhagic site for recurrent bleeding: prespecified analysis in the Japan Adult Moyamoya trial. Stroke. 2016 Jan;47(1):37-43. Abstract

46. Rutten-Jacobs LC, Larsson SC, Malik R, et al. Genetic risk, incident stroke, and the benefits of adhering to a healthy lifestyle: cohort study of 306 473 UK Biobank participants. BMJ. 2018 Oct 24;363:k4168.Full text  Abstract

47. Pandian JD, Gall SL, Kate MP, et al. Prevention of stroke: a global perspective. Lancet. 2018 Oct 6;392(10154):1269-78. Abstract

48. Feng Q, Fan S, Wu Y, et al. Adherence to the dietary approaches to stop hypertension diet and risk of stroke: a meta-analysis of prospective studies. Medicine (Baltimore). 2018 Sep;97(38):e12450.Full text  Abstract

49. Blacquiere D, Lindsay MP, Foley N, et al. Canadian stroke best practice recommendations: telestroke best practice guidelines update 2017. Int J Stroke. 2017 Oct;12(8):886-95.Full text  Abstract

50. Demaerschalk BM, Berg J, Chong BW, et al. American Telemedicine Association: telestroke guidelines. Telemed J E Health. 2017 May;23(5):376-89.Full text  Abstract

51. Hwang DY, Dell CA, Sparks MJ, et al. Clinician judgment vs formal scales for predicting intracerebral hemorrhage outcomes. Neurology. 2016 Jan 12;86(2):126-33. Abstract

52. McKinney JS, Kostis WJ. Statin therapy and the risk of intracerebral hemorrhage: a meta-analysis of 31 randomized controlled trials. Stroke. 2012 Aug;43(8):2149-56. Abstract

53. Biffi A, Devan WJ, Anderson CD, et al. Statin use and outcome after intracerebral hemorrhage: case-control study and meta-analysis. Neurology. 2011 May 3;76(18):1581-8.Full text  Abstract

54. Priglinger M, Arima H, Anderson C, et al; INTERACT Investigators. No relationship of lipid-lowering agents to hematoma growth: pooled analysis of the Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trials studies. Stroke. 2015 Mar;46(3):857-9.Full text  Abstract

55. Ma Y, Li Z, Chen L, et al. Blood lipid levels, statin therapy and the risk of intracerebral hemorrhage. Lipids Health Dis. 2016 Mar 1;15:43.Full text  Abstract

56. Passero S, Rocchi R, Rossi S, et al. Seizures after spontaneous supratentorial intracerebral hemorrhage. Epilepsia. 2002 Oct;43(10):1175-80. Abstract

57. Runchey S, McGee S. Does this patient have a hemorrhagic stroke?: clinical findings distinguishing hemorrhagic stroke from ischemic stroke. JAMA. 2010 Jun 9;303(22):2280-6. Abstract

58. Cordonnier C, Demchuk A, Ziai W, et al. Intracerebral haemorrhage: current approaches to acute management. Lancet. 2018 Oct 6;392(10154):1257-68. Abstract

59. Kleindorfer DO, Towfighi A, Chaturvedi S, et al. 2021 guideline for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline from the American Heart Association/American Stroke Association. Stroke. 2021 Jul;52(7):e364-e467.Full text  Abstract

60. Bailey RD, Hart RG, Benavente O, et al. Recurrent brain hemorrhage is more frequent than ischemic stroke after intracranial hemorrhage. Neurology. 2001 Mar 27;56(6):773-7. Abstract

61. Wada R, Aviv RI, Fox AJ, et al. CT angiography "spot sign" predicts hematoma expansion in acute intracerebral hemorrhage. Stroke. 2007 Apr;38(4):1257-62.Full text  Abstract

62. Goldstein JN, Fazen LE, Snider R, et al. Contrast extravasation on CT angiography predicts hematoma expansion in intracerebral hemorrhage. Neurology. 2007 Mar 20;68(12):889-94. Abstract

63. Delgado Almandoz JE, Yoo AJ, Stone MJ, et al. Systematic characterization of the computed tomography angiography spot sign in primary intracerebral hemorrhage identifies patients at highest risk for hematoma expansion: the spot sign score. Stroke. 2009 Sep;40(9):2994-3000.Full text  Abstract

64. Almandoz JE, Yoo AJ, Stone MJ, et al. The spot sign score in primary intracerebral hemorrhage identifies patients at highest risk of in-hospital mortality and poor outcome among survivors. Stroke. 2010 Jan;41(1):54-60. Abstract

65. Naidech AM. Diagnosis and management of spontaneous intracerebral hemorrhage. Continuum (Minneap Minn). 2015 Oct;21(5 Neurocritical Care):1288-98. Abstract

66. Viswanathan A, Rakich SM, Engel C, et al. Antiplatelet use after intracerebral hemorrhage. Neurology. 2006 Jan 24;66(2):206-9. Abstract

67. Mittal S, Wu Z, Neelavalli J, et al. Susceptibility-weighted imaging: technical aspects and clinical applications, part 2. AJNR Am J Neuroradiol. 2009 Feb;30(2):232-52.Full text  Abstract

68. Catanzaro JN, Meraj PM, Zheng S, et al. Electrocardiographic T-wave changes underlying acute cardiac and cerebral events. Am J Emerg Med. 2008 Jul;26(6):716-20. Abstract

69. Zhu XL, Chan MS, Poon WS. Spontaneous intracranial hemorrhage: which patients need diagnostic cerebral angiography? A prospective study of 206 cases and review of the literature. Stroke. 1997 Jul;28(7):1406-9.Full text  Abstract

70. Jeerakathil T, Wolf PA, Beiser A, et al. Cerebral microbleeds: prevalence and associations with cardiovascular risk factors in the Framingham Study. Stroke. 2004 Aug;35(8):1831-5.Full text  Abstract

71. Chalela JA, Kidwell CS, Nentwich LM, et al. Magnetic resonance imaging and computed tomography in emergency assessment of patients with suspected acute stroke: a prospective comparison. Lancet. 2007 Jan 27;369(9558):293-8.Full text  Abstract

72. Knudsen KA, Rosand J, Karluk D, et al. Clinical diagnosis of cerebral amyloid angiopathy: validation of the Boston criteria. Neurology. 2001 Feb 27;56(4):537-9. Abstract

73. American College of Radiology. ACR appropriateness criteria: cerebrovascular disease. 2016 [internet publication].Full text

74. Boulanger JM, Lindsay MP, Gubitz G, et al. Canadian Stroke best practice recommendations for acute stroke management: prehospital, emergency department, and acute inpatient stroke care, 6th edition, update 2018. Int J Stroke. 2018 Dec;13(9):949-84.Full text  Abstract

75. Stroke Foundation (Australia). Clinical guidelines for stroke management. 2022 [internet publication].Full text

76. Irimia P, Asenbaum S, Brainin M, et al; European Federation of Neurological Societies. Use of imaging in cerebrovascular disease. In: Gilhus NE, Barnes MP, Brainin M, eds. European handbook of neurological management, vol 1, 2nd ed. London, UK: Blackwell Publishing; 2011:19-34.

77. Adeoye O, Nyström KV, Yavagal DR, et al. Recommendations for the establishment of stroke systems of care: a 2019 update. Stroke. 2019 Jul;50(7):e187-210.Full text  Abstract

78. Langhorne P, Ramachandra S, Stroke Unit Trialists' Collaboration. Organised inpatient (stroke unit) care for stroke: network meta-analysis. Cochrane Database Syst Rev. 2020 Apr 23;(4):CD000197.Full text  Abstract

79. Soar J, Böttiger BW, Carli P, et al. European Resuscitation Council Guidelines 2021: adult advanced life support. Resuscitation. 2021 Apr;161:115-51.Full text  Abstract

80. Colquhoun MC, Handley AJ, Evans TR. ABC of resuscitation. 5th ed. London: BMJ Publishing Group; 2004.

81. Chrimes N, Higgs A, Hagberg CA, et al. Preventing unrecognised oesophageal intubation: a consensus guideline from the Project for Universal Management of Airways and international airway societies. Anaesthesia. 2022 Aug 17 [Epub ahead of print].Full text  Abstract

82. Mendelow AD, Gregson BA, Fernandes HM, et al. Early surgery versus initial conservative treatment in patients with spontaneous supratentorial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage (STICH): a randomised trial. Lancet. 2005 Jan 29-Feb 4;365(9457):387-97. Abstract

83. Mendelow AD, Gregson BA, Rowan EN, et al; STICH II Investigators. Early surgery versus initial conservative treatment in patients with spontaneous supratentorial lobar intracerebral haematomas (STICH II): a randomised trial. Lancet. 2013 Aug 3;382(9890):397-408. Abstract

84. Scaggiante J, Zhang X, Mocco J, et al. Minimally invasive surgery for intracerebral hemorrhage: an updated meta-analysis of randomized controlled trials. Stroke. 2018 Nov;49(11):2612-20.Full text  Abstract

85. Tang Y, Yin F, Fu D, et al. Efficacy and safety of minimal invasive surgery treatment in hypertensive intracerebral hemorrhage: a systematic review and meta-analysis. BMC Neurol. 2018 Sep 3;18(1):136.Full text  Abstract

86. Xia Z, Wu X, Li J, et al. Minimally invasive surgery is superior to conventional craniotomy in patients with spontaneous supratentorial intracerebral hemorrhage: a systematic review and meta-analysis. World Neurosurg. 2018 Jul;115:266-73. Abstract

87. Cavallo C, Zhao X, Abou-Al-Shaar H, et al. Minimally invasive approaches for the evacuation of intracerebral hemorrhage: a systematic review. J Neurosurg Sci. 2018 Dec;62(6):718-33. Abstract

88. Zhou X, Chen J, Li Q, et al. Minimally invasive surgery for spontaneous supratentorial intracerebral hemorrhage: a meta-analysis of randomized controlled trials. Stroke. 2012 Nov;43(11):2923-30.Full text  Abstract

89. Hanley DF, Thompson RE, Rosenblum M, et al. Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label, blinded endpoint phase 3 trial. Lancet. 2019 Mar 9;393(10175):1021-32. Abstract

90. Li Q, Gao Y, Xin W, et al. Meta-analysis of prognosis of different treatments for symptomatic moyamoya disease. World Neurosurg. 2019 Jul;127:354-61. Abstract

91. Jeon JP, Kim JE, Cho WS, et al. Meta-analysis of the surgical outcomes of symptomatic moyamoya disease in adults. J Neurosurg. 2018 Mar;128(3):793-9.Full text  Abstract

92. Wang G, Zhang X, Feng M, et al. Efficacy of surgical treatment on the recurrent stroke prevention for adult patients with hemorrhagic moyamoya disease. J Craniofac Surg. 2017 Nov;28(8):2113-6. Abstract

93. Wei W, Chen X, Yu J, et al. Risk factors for postoperative stroke in adult patients with moyamoya disease: a systematic review with meta-analysis. BMC Neurol. 2019 May 15;19(1):98.Full text  Abstract

94. Martino R, Foley N, Bhogal S, et al. Dysphagia after stroke: incidence, diagnosis, and pulmonary complications. Stroke. 2005 Dec;36(12):2756-63.Full text  Abstract

95. Warusevitane A, Karunatilake D, Sim J, et al. Safety and effect of metoclopramide to prevent pneumonia in patients with stroke fed via nasogastric tubes trial. Stroke. 2015 Feb;46(2):454-60.Full text  Abstract

96. Powers WJ, Rabinstein AA, Ackerson T, et al. 2018 guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2018 Mar;49(3):e46-99.Full text  Abstract

97. Bath PM, Woodhouse L, Scutt P, et al; ENOS Trial Investigators. Efficacy of nitric oxide, with or without continuing antihypertensive treatment, for management of high blood pressure in acute stroke (ENOS): a partial-factorial randomised controlled trial. Lancet. 2015 Feb 14;385(9968):617-28.Full text  Abstract

98. Anderson CS, Huang Y, Wang JG, et al. Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT): a randomised pilot trial. Lancet Neurol. 2008 May;7(5):391-9. Abstract

99. Qureshi AI, Foster LD, Lobanova I, et al. Intensive blood pressure lowering in patients with moderate to severe grade acute cerebral hemorrhage: post hoc analysis of Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH)-2 Trial. Cerebrovasc Dis. 2020;49(3):244-52.Full text  Abstract

100. Mayer SA, Brun NC, Begtrup K, et al. Recombinant activated factor VII for acute intracerebral hemorrhage. N Engl J Med. 2005 Feb 24;352(8):777-85.Full text  Abstract

101. Frontera JA, Lewin JJ 3rd, Rabinstein AA, et al. Guideline for reversal of antithrombotics in intracranial hemorrhage: executive summary. A statement for healthcare professionals from the Neurocritical Care Society and the Society of Critical Care Medicine. Crit Care Med. 2016 Dec;44(12):2251-7.Full text  Abstract

102. Garcia DA, Baglin TP, Weitz JI, et al. Parenteral anticoagulants: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest. 2012 Feb;141(2 suppl):e24-43S.Full text  Abstract

103. Pollack CV Jr, Reilly PA, Eikelboom J, et al. Idarucizumab for dabigatran reversal. N Engl J Med. 2015 Aug 6;373(6):511-20.Full text  Abstract

104. Connolly SJ, Crowther M, Eikelboom JW, et al. Full study report of andexanet alfa for bleeding associated with factor Xa inhibitors. N Engl J Med. 2019 Apr 4;380(14):1326-35.Full text  Abstract

105. Al-Shahi Salman R, Law ZK, Bath PM, et al. Haemostatic therapies for acute spontaneous intracerebral haemorrhage. Cochrane Database Syst Rev. 2018 Apr 17;(4):CD005951.Full text  Abstract

106. Thompson BB, Bejot Y, Caso V, et al. Prior antiplatelet therapy and outcome following intracerebral hemorrhage: a systematic review. Neurology. 2010 Oct 12;75(15):1333-42. Abstract

107. Naidech AM, Jovanovic B, Liebling S, et al. Reduced platelet activity is associated with early clot growth and worse 3-month outcome after intracerebral hemorrhage. Stroke. 2009 Jul;40(7):2398-401.Full text  Abstract

108. Baharoglu MI, Cordonnier C, Al-Shahi Salman R, et al. Platelet transfusion versus standard care after acute stroke due to spontaneous cerebral haemorrhage associated with antiplatelet therapy (PATCH): a randomised, open-label, phase 3 trial. Lancet. 2016 Jun 25;387(10038):2605-13. Abstract

109. den Hertog HM, van der Worp HB, van Gemert HM, et al; PAIS Investigators. The Paracetamol (Acetaminophen) In Stroke (PAIS) trial: a multicentre, randomised, placebo-controlled, phase III trial. Lancet Neurol. 2009 May;8(5):434-40. Abstract

110. de Ridder IR, den Hertog HM, van Gemert HM, et al. PAIS 2 (Paracetamol [Acetaminophen] in Stroke 2): results of a randomized, double-blind placebo-controlled clinical trial. Stroke. 2017 Apr;48(4):977-82.Full text  Abstract

111. ElSayed NA, Aleppo G, Aroda VR, et al. 16. Diabetes care in the hospital: standards of care in diabetes-2023. Diabetes Care. 2023 Jan 1;46(suppl 1):S267-78.Full text  Abstract

112. Saxena A, Anderson CS, Wang X, et al. Prognostic significance of hyperglycemia in acute intracerebral hemorrhage: the INTERACT2 Study. Stroke. 2016 Mar;47(3):682-8.Full text  Abstract

113. Zheng J, Yu Z, Ma L, et al. Association between blood glucose and functional outcome in intracerebral hemorrhage: a systematic review and meta-analysis. World Neurosurg. 2018 Jun;114:e756-65. Abstract

114. Skaf E, Stein PD, Beemath A, et al. Venous thromboembolism in patients with ischemic and hemorrhagic stroke. Am J Cardiol. 2005 Dec 15;96(12):1731-3. Abstract

115. Nyquist P, Bautista C, Jichici D, et al. Prophylaxis of venous thrombosis in neurocritical care patients: an evidence-based guideline. A statement for healthcare professionals from the Neurocritical Care Society. Neurocrit Care. 2016 Feb;24(1):47-60. Abstract

116. Dennis M, Sandercock P, Reid J, et al; CLOTS (Clots in Legs Or sTockings after Stroke) Trials Collaboration. Effectiveness of intermittent pneumatic compression in reduction of risk of deep vein thrombosis in patients who have had a stroke (CLOTS 3): a multicentre randomised controlled trial. Lancet. 2013 Aug 10;382(9891):516-24.Full text  Abstract

117. Zhang D, Li F, Li X, et al. Effect of intermittent pneumatic compression on preventing deep vein thrombosis among stroke patients: a systematic review and meta-analysis. Worldviews Evid Based Nurs. 2018 Jun;15(3):189-96. Abstract

118. Boeer A, Voth E, Henze T, et al. Early heparin therapy in patients with spontaneous intracerebral haemorrhage. J Neurol Neurosurg Psychiatry. 1991 May;54(5):466-7.Full text  Abstract

119. Winstein CJ, Stein J, Arena R, et al. Guidelines for adult stroke rehabilitation and recovery: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2016 Jun;47(6):e98-e169.Full text  Abstract

120. Cumming TB, Churilov L, Collier J, et al. Early mobilization and quality of life after stroke: findings from AVERT. Neurology. 2019 Aug 13;93(7):e717-28.Full text  Abstract

121. Liu N, Cadilhac DA, Andrew NE, et al. Randomized controlled trial of early rehabilitation after intracerebral hemorrhage stroke: difference in outcomes within 6 months of stroke. Stroke. 2014 Dec;45(12):3502-7.Full text  Abstract

122. Sall J, Eapen BC, Tran JE, et al. The management of stroke rehabilitation: a synopsis of the 2019 U.S. Department of Veterans Affairs and U.S. Department of Defense clinical practice guideline. Ann Intern Med. 2019 Dec 17;171(12):916-24.Full text  Abstract

123. Barclay RE, Stevenson TJ, Poluha W, et al. Mental practice for treating upper extremity deficits in individuals with hemiparesis after stroke. Cochrane Database Syst Rev. 2020 May 25;5:CD005950.Full text  Abstract

124. FOCUS Trial Collaboration. Effects of fluoxetine on functional outcomes after acute stroke (FOCUS): a pragmatic, double-blind, randomised, controlled trial. Lancet. 2019 Jan 19;393(10168):265-74.Full text  Abstract

125. AFFINITY Trial Collaboration. Safety and efficacy of fluoxetine on functional outcome after acute stroke (AFFINITY): a randomised, double-blind, placebo-controlled trial. Lancet Neurol. 2020 Aug;19(8):651-60. Abstract

126. Legg LA, Rudberg AS, Hua X, et al. Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery. Cochrane Database Syst Rev. 2021 Nov 15;11:CD009286.Full text  Abstract

127. Gibbons EM, Thomson AN, de Noronha M, et al. Are virtual reality technologies effective in improving lower limb outcomes for patients following stroke - a systematic review with meta-analysis. Top Stroke Rehabil. 2016 Dec;23(6):440-57. Abstract

128. Palma GC, Freitas TB, Bonuzzi GM, et al. Effects of virtual reality for stroke individuals based on the International Classification of Functioning and Health: a systematic review. Top Stroke Rehabil. 2017 May;24(4):269-78. Abstract

129. Chu DK, Kim LH, Young PJ, et al. Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis. Lancet. 2018 Apr 28;391(10131):1693-705. Abstract

130. Siemieniuk RAC, Chu DK, Kim LH, et al. Oxygen therapy for acutely ill medical patients: a clinical practice guideline. BMJ. 2018 Oct 24;363:k4169.Full text  Abstract

131. Schwarz S, Hafner K, Aschoff A, et al. Incidence and prognostic significance of fever following intracerebral hemorrhage. Neurology. 2000 Jan 25;54(2):354-61. Abstract

132. Takagi T, Hara HJ. Protective effects of cilostazol against hemorrhagic stroke: current and future perspectives. Pharmacol Sci. 2016 Jul;131(3):155-61. Abstract

133. Elsner B, Kugler J, Pohl M, et al. Transcranial direct current stimulation (tDCS) for improving activities of daily living, and physical and cognitive functioning, in people after stroke. Cochrane Database Syst Rev. 2020 Nov 11;(11):CD009645.Full text  Abstract

134. Dionísio A, Duarte IC, Patrício M, et al. Transcranial magnetic stimulation as an intervention tool to recover from language, swallowing and attentional deficits after stroke: a systematic review. Cerebrovasc Dis. 2018;46(3-4):178-85.Full text  Abstract

135. Dionísio A, Duarte IC, Patrício M, et al. The use of repetitive transcranial magnetic stimulation for stroke rehabilitation: a systematic review. J Stroke Cerebrovasc Dis. 2018 Jan;27(1):1-31. Abstract

136. Bundy DT, Souders L, Baranyai K, et al. Contralesional brain-computer interface control of a powered exoskeleton for motor recovery in chronic stroke survivors. Stroke. 2017 Jul;48(7):1908-15.Full text  Abstract

137. Hemphill JC 3rd, Adeoye OM, Alexander DN, et al. Clinical performance measures for adults hospitalized with intracerebral hemorrhage: performance measures for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2018 Jul;49(7):e243-61.Full text  Abstract

138. Hobbs FR, Taylor CJ, Jan Geersing G, et al. European Primary Care Cardiovascular Society (EPCCS) consensus guidance on stroke prevention in atrial fibrillation (SPAF) in primary care. Eur J Prev Cardiol. 2016 Mar;23(5):460-73.Full text  Abstract

139. Steiner T, Al-Shahi Salman R, Beer R, et al. European Stroke Organisation (ESO) guidelines for the management of spontaneous intracerebral hemorrhage. Int J Stroke. 2014 Oct;9(7):840-55.Full text  Abstract

140. Hemphill JC 3rd, Farrant M, Neill TA Jr. Prospective validation of the ICH Score for 12-month functional outcome. Neurology. 2009 Oct 6;73(14):1088-94. Abstract

141. Rost NS, Smith EE, Chang Y, et al. Prediction of functional outcome in patients with primary intracerebral hemorrhage: the FUNC score. Stroke. 2008 Aug;39(8):2304-9.Full text  Abstract

142. Morgenstern LB, Zahuranec DB, Sánchez BN, et al. Full medical support for intracerebral hemorrhage. Neurology. 2015 Apr 28;84(17):1739-44. Abstract

143. Saunders DH, Sanderson M, Hayes S, et al. Physical fitness training for stroke patients. Cochrane Database Syst Rev. 2020 Mar 20;(3):CD003316.Full text  Abstract

144. Macellari F, Paciaroni M, Agnelli G, et al. Neuroimaging in intracerebral hemorrhage. Stroke. 2014 Mar;45(3):903-8.Full text  Abstract

145. Boulouis G, Morotti A, Goldstein JN, et al. Intensive blood pressure lowering in patients with acute intracerebral haemorrhage: clinical outcomes and haemorrhage expansion. Systematic review and meta-analysis of randomised trials. J Neurol Neurosurg Psychiatry. 2017 Apr;88(4):339-45. Abstract

146. Carandini T, Bozzano V, Scarpini E, et al. Intensive versus standard lowering of blood pressure in the acute phase of intracranial haemorrhage: a systematic review and meta-analysis. Intern Emerg Med. 2018 Jan;13(1):95-105. Abstract

147. Whelton PK, Carey RM, Aronow WS, et al. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Hypertension. 2018 Jun;71(6):e13-115.Full text  Abstract

148. D'Isabella NT, Shkredova DA, Richardson JA, et al. Effects of exercise on cardiovascular risk factors following stroke or transient ischemic attack: a systematic review and meta-analysis. Clin Rehabil. 2017 Dec;31(12):1561-72. Abstract

149. Eckman MH, Rosand J, Knudsen KA, et al. Can patients be anticoagulated after intracerebral hemorrhage? A decision analysis. Stroke. 2003 Jul;34(7):1710-6.Full text  Abstract

150. Biffi A, Kuramatsu JB, Leasure A, et al. Oral anticoagulation and functional outcome after intracerebral hemorrhage. Ann Neurol. 2017 Nov;82(5):755-65. Abstract

151. Katsanos AH, Mavridis D, Parissis J, et al. Novel oral anticoagulants for the secondary prevention of cerebral ischemia: a network meta-analysis. Ther Adv Neurol Disord. 2016 Sep;9(5):359-68.Full text  Abstract

152. Bentz BA. Nonvitamin K antagonist oral anticoagulants in everyday practice: stroke prevention in atrial fibrillation and treatment of venous thromboembolism. J Am Assoc Nurse Pract. 2015 Dec;27(12):721-31. Abstract

153. Brønnum Nielsen P, Skjøth F, Søgaard M, et al. Non-vitamin K antagonist oral anticoagulants versus warfarin in atrial fibrillation patients with intracerebral hemorrhage. Stroke. 2019 Apr;50(4):939-46.Full text  Abstract

154. Murthy SB, Gupta A, Merkler AE, et al. Restarting anticoagulant therapy after intracranial hemorrhage: a systematic review and meta-analysis. Stroke. 2017 Jun;48(6):1594-600.Full text  Abstract

155. Oertel LB, Fogerty AE. Use of direct oral anticoagulants for stroke prevention in elderly patients with nonvalvular atrial fibrillation. J Am Assoc Nurse Pract. 2017 Sep;29(9):551-61. Abstract

156. Raccah BH, Perlman A, Danenberg HD, et al. Major bleeding and hemorrhagic stroke with direct oral anticoagulants in patients with renal failure: systematic review and meta-analysis of randomized trials. Chest. 2016 Jun;149(6):1516-24. Abstract

157. Tereshchenko LG, Henrikson CA, Cigarroa J, et al. Comparative effectiveness of interventions for stroke prevention in atrial fibrillation: a network meta-analysis. J Am Heart Assoc. 2016 May 20;5(5):e003206.Full text  Abstract

158. Perry LA, Berge E, Bowditch J, et al. Antithrombotic treatment after stroke due to intracerebral haemorrhage. Cochrane Database Syst Rev. 2017 May 25;(5):CD012144.Full text  Abstract

159. RESTART Collaboration. Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial. Lancet. 2019 Jun 29;393(10191):2613-23.Full text  Abstract

160. Li L, Geraghty OC, Mehta Z, et al. Age-specific risks, severity, time course, and outcome of bleeding on long-term antiplatelet treatment after vascular events: a population-based cohort study. Lancet. 2017 Jul 29;390(10093):490-9.Full text  Abstract

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