Hemangioma

References

Key articles

Krowchuk DP, Frieden IJ, Mancini AJ, et al. Clinical practice guideline for the management of infantile hemangiomas. Pediatrics. 2019 Jan;143(1): e20183475.Full text  Abstract

Darrow DH, Greene AK, Mancini AJ, et al. Diagnosis and management of infantile hemangioma. Pediatrics. 2015 Oct;136(4):e1060-104.Full text  Abstract

Reference articles

1. Krowchuk DP, Frieden IJ, Mancini AJ, et al. Clinical practice guideline for the management of infantile hemangiomas. Pediatrics. 2019 Jan;143(1): e20183475.Full text  Abstract

2. Garzon MC. Infantile hemangioma. In: Callen JP, Horn TD, Mancini AJ, et al, eds. Dermatology. Vol. 2. 2nd ed. St. Louis, MO: Elsevier; 2008:1565-80.

3. Chang LC, Haggstrom AN, Drolet BA, et al. Growth characteristics of infantile hemangiomas: implications for management. Pediatrics. 2008 Aug;122(2):360-7. Abstract

4. Requena L, Sangueza OP. Cutaneous vascular proliferations. Part II. Hyperplasias and benign neoplasms. J Am Acad Dermatol. 1997 Dec;37(6):887-919. Abstract

5. Wananukul S. Clinical manifestation and management of hemangiomas of infancy. J Med Assoc Thai. 2002 Jun;85(suppl 1):S280-5. Abstract

6. Haggstrom AN, Lammer EJ, Schneider RA, et al. Patterns of infantile hemangiomas: new clues to hemangioma pathogenesis and embryonic facial development. Pediatrics. 2006 Mar;117(3):698-703. Abstract

7. Chiller KG, Passaro D, Friedan IJ. Hemangiomas of infancy: clinical characteristics, morphologic subtypes, and their relationship to race, ethnicity and sex. Arch Dermatol. 2002 Dec;138(12):1567-76.Full text  Abstract

8. Metry D, Heyer G, Hess C, et al. Consensus statement on diagnostic criteria for PHACE syndrome. Pediatrics. 2009 Nov;124(5):1447-56. Abstract

9. Goldberg NS, Hebert AA, Esterly NB. Sacral hemangioma and multiple congenital abnormalities. Arch Dermatol. 1986 Jun;122(6):684-7. Abstract

10. Grevelink SV, Mulliken JB. Vascular anomalies and tumors of skin and subcutaneous tissues. In: Freedberg IM, Eisen AZ, Wolff K, et al, eds. Fitzpatrick's dermatology in general medicine. Vol. 1. 6th ed. New York, NY: McGraw-Hill; 2003:1002-26.

11. Glick ZR, Frieden IJ, Garzon MC, et al. Diffuse neonatal hemangiomatosis: an evidence-based review of case reports in the literature. J Am Acad Dermatol. 2012 Nov;67(5):898-903. Abstract

12. Horii KA, Drolet BA, Frieden IJ, et al. Prospective study of the frequency of hepatic hemangiomas in infants with multiple cutaneous infantile hemangiomas. Pediatr Dermatol. 2011 May-Jun;28(3):245-53. Abstract

13. Paller A, Mancini A. Hurwitz clinical pediatric dermatology. 4th ed. Philadelphia, PA: Saunders; 2011:268-302.

14. Darrow DH, Greene AK, Mancini AJ, et al. Diagnosis and management of infantile hemangioma. Pediatrics. 2015 Oct;136(4):e1060-104.Full text  Abstract

15. Kilcline C, Friedan IJ. Infantile hemangiomas: how common are they? A systematic review of the medical literature. Pediatr Dermatol. 2008 Mar-Apr;25(2):168-73. Abstract

16. Bruckner AL, Friedan IJ. Hemangiomas of infancy. J Am Acad Dermatol. 2003 Apr;48(4):477-93. Abstract

17. Drolet BA, Swanson EA, Frieden IJ, et al. Infantile hemangiomas: an emerging health issue linked to an increased rate of low birth weight infants. J Pediatr. 2008 Nov;153(5):712-5. Abstract

18. Smith CJF, Friedlander SF, Guma M, et al. Infantile hemangiomas: an updated review on risk factors, pathogenesis, and treatment. Birth Defects Res. 2017 Jul 3;109(11):809-15.Full text  Abstract

19. Hemangioma Investigator Group, Haggstrom AN, Drolet, BA, et al. Prospective study of infantile hemangiomas: demographic, prenatal, and perinatal characteristics. J Pediatr. 2007 Mar;150(3):291-4. Abstract

20. Barnes CM, Christison-Lagay EA, Folkman J. The placenta theory and the origin of infantile hemangioma. Lymphat Res Biol. 2007;5(4):245-55. Abstract

21. Pittman KM, Losken HW, Kleinman ME, et al. No evidence for maternal-fetal microchimerism in infantile hemangioma: a molecular genetic investigation. J Invest Dermatol. 2006 Nov;126(11):2533-8.Full text  Abstract

22. Regnier S, Dupin N, Le Danff C, et al. Endothelial cells in infantile haemangiomas originate from the child and not from the mother (a fluorescence in situ hybridization-based study). Br J Dermatol. 2007 Jul;157(1):158-60. Abstract

23. Haggstrom AN, Drolet BA, Baselga E, et al. Prospective study of infantile hemangiomas: clinical characteristics predicting complications and treatment. Pediatrics. 2006 Sep;118(3):882-7. Abstract

24. Paltiel HJ, Burrows PE, Kozakewich HP, et al. Soft-tissue vascular anomalies: utility of US for diagnosis. Radiology. 2000 Mar;214(3):747-54. Abstract

25. Kern S, Niemeyer C, Darge K, et al. Differentiation of vascular birthmarks by MR imaging. An investigation of hemangiomas, venous and lymphatic malformations. Acta Radiol. 2000 Sep;41(5):453-7. Abstract

26. Kitami M. Diffusion-weighted imaging as a routine MRI protocol for the evaluation of 'infantile hemangioma'. Clin Imaging. 2017 Nov - Dec;46:121. Abstract

27. Weedon D. Vascular tumors. In: Houston MJ, ed. Skin pathology. 2nd ed. New York, NY: Churchill Livingston; 2002:1001-43.

28. North PE, Waner M, Mizeracki A, et al. GLUT1: a newly discovered immunohistochemical marker for juvenile hemangioma. Hum Pathol. 2000 Jan;31(1):11-22. Abstract

29. Bree AF, Siegfried E, Sotelo-Avila C, et al. Infantile hemangioma: speculation on placental trophoblastic origin. Arch Dermatol. 2001 May;137(5):573-7.Full text  Abstract

30. North PE, Waner M, James CA, et al. Congenital nonprogressive hemangioma: a distinct clinicopathological entity unlike infantile hemangioma. Arch Dermatol. 2001 Dec;137(12):1607-20.Full text  Abstract

31. Metry DW, Dowd CF, Barkovich AJ, et al. The many faces of PHACE syndrome. J Pediatr. 2001 Jul;139(1):117-23. [Erratum in: J Pediatr 2001 Sep;139(3):470.] Abstract

32. Legiehn GM, Heran MK. Venous malformations: classification, development, diagnosis, and interventional radiologic management. Radiol Clin North Am. 2008 May;46(3):545-97. Abstract

33. Enjolras O. Vascular malformations. In: Callen JP, Horn TD, Mancini AJ, et al, eds. Dermatology. Vol. 2. 2nd ed. St. Louis, MO: Elsevier; 2008:1581-95.

34. Pandey A, Gangopadhyay AN, Sharma SP, et al. Conservative management of ulcerated haemangioma - twenty years experience. Int Wound J. 2009 Feb;6(1):59-62. Abstract

35. Berenguer B, Mulliken JB, Enjolras O, et al. Rapidly involuting congenital hemangioma: clinical and histopathologic features. Pediatr Dev Pathol. 2003 Nov-Dec;6(6):495-510. Abstract

36. Requena C, Miranda L, Canete A, et al. Congenital fibrosarcoma simulating congenital hemangioma. Pediatr Dermatol. 2008 Jan-Feb;25(1):141-4. Abstract

37. Yan AC, Chamlin SL, Liang MG, et al. Congenital infantile fibrosarcoma: a masquerader of ulcerated hemangioma. Pediatr Dermatol. 2006 Jul-Aug;23(4):330-4. Abstract

38. North PE, Kincannon J. Vascular neoplasms and neoplastic-like proliferations. In: Callen JP, Horn TD, Mancini AJ, et al, eds. Dermatology. Vol. 2. 2nd ed. St. Louis, MO: Elsevier; 2008:1771-94.

39. Izadpanah A, Izadpanah A, Kanevsky J, et al. Propranolol versus corticosteroids in the treatment of infantile hemangioma: a systematic review and meta-analysis. Plast Reconstr Surg. 2013 Mar;131(3):601-13. Abstract

40. Drolet BA, Frommelt PC, Chamlin SL, et al. Initiation and use of propranolol for infantile hemangioma: report of a consensus conference. Pediatrics. 2013 Jan;131(1):128-40. Abstract

41. Léauté-Labrèze C, Hoeger P, Mazereeuw-Hautier J, et al. A randomized, controlled trial of oral propranolol in infantile hemangioma. N Engl J Med. 2015 Feb 19;372(8):735-46.Full text  Abstract

42. Léauté-Labrèze C, Dumas de la Roque E, Hubiche T, et al. Propranolol for severe hemangiomas of infancy. N Engl J Med. 2008 Jun 12;358(24):2649-51. Abstract

43. Zaher H, Rasheed H, Hegazy RA, et al. Oral propranolol: an effective, safe treatment for infantile hemangiomas. Eur J Dermatol. 2011 Jul-Aug;21(4):558-63. Abstract

44. Fuchsmann C, Quintal MC, Giguere C, et al. Propranolol as first-line treatment of head and neck hemangiomas. Arch Otolaryngol Head Neck Surg. 2011 May;137(5):471-8. Abstract

45. Missoi TG, Lueder GT, Gilbertson K, et al. Oral propranolol for treatment of periocular infantile hemangiomas. Arch Ophthalmol. 2011 Jul;129(7):899-903. Abstract

46. Peridis S, Pilgrim G, Athanasopoulos I, et al. A meta-analysis on the effectiveness of propranolol for the treatment of infantile airway haemangiomas. Int J Pediatr Otorhinolaryngol. 2011 Apr;75(4):455-60. Abstract

47. Hong E, Fischer G. Propranolol for recalcitrant ulcerated hemangioma of infancy. Pediatr Dermatol. Pediatr Dermatol. 2012 Jan-Feb;29(1):64-7. Abstract

48. Mazereeuw-Hautier J, Hoeger PH, Benlahrech S, et al. Efficacy of propranolol in hepatic infantile hemangiomas with diffuse neonatal hemangiomatosis. J Pediatr. 2010 Aug;157(2):340-2. Abstract

49. Marqueling AL, Oza V, Frieden IJ, et al. Propranolol and infantile hemangiomas four years later: a systematic review. Pediatr Dermatol. 2013 Mar-Apr;30(2):182-91. Abstract

50. de Graaf M, Breur JM, Raphael MF, et al. Adverse effects of propranolol when used in the treatment of hemangiomas: A case series of 28 infants. J Am Acad Dermatol. 2011 Aug;65(2):320-7. Abstract

51. Holland KE, Frieden IJ, Frommelt PC, et al. Hypoglycemia in children taking propranolol for the treatment of infantile hemangioma. Arch Dermatol. 2010 Jul;146(7):775-8.Full text  Abstract

52. Lawley LP, Siegfried E, Todd JL. Propranolol treatment for hemangioma of infancy: risks and recommendations. Pediatr Dermatol. 2009 Sep-Oct;26(5):610-4.Full text  Abstract

53. Ni N, Langer P, Wagner R, et al. Topical timolol for periocular hemangioma: report of further study. Arch Ophthalmol. 2011 Mar;129(3):377-9. Abstract

54. Pope E, Chakkittakandiyil A. Topical timolol gel for infantile hemangiomas: a pilot study. Arch Dermatol. 2010 May;146(5):564-5.Full text  Abstract

55. National Institute for Health and Care Excellence. Infantile haemangioma: topical timolol. August 2015 [internet publication].Full text

56. Pope E, Krafchik BR, Macarthur C, et al. Oral versus high-dose pulse corticosteroids for problematic infantile hemangiomas: a randomized, controlled trial. Pediatrics. 2007 Jun;119(6):e1239-47. Abstract

57. Jalil S, Akhtar J, Ahmed S. Corticosteroids therapy in the management of infantile cutaneous hemangioma. J Coll Physicians Surg Pak. 2006 Oct;16(10):662-5. Abstract

58. Rossler J, Wehl G, Niemeyer CM. Evaluating systemic prednisone therapy for proliferating haemangioma in infancy. Eur J Pediatr. 2008 Jul;167(7):813-5. Abstract

59. Bennett ML, Fleischer AB Jr., Chamlin SL, et al. Oral corticosteroid use is effective for cutaneous hemangiomas: an evidence-based evaluation. Arch Dermatol. 2001 Sep;137(9):1208-13. Abstract

60. George ME, Sharma V, Jacobson J, et al. Adverse effects of systemic glucocorticosteroid therapy in infants with hemangiomas. Arch Dermatol. 2004 Aug;140(8):963-9.Full text  Abstract

61. Lomenick JP, Reifschneider KL, Lucky AW, et al. Prevalence of adrenal insufficiency following systemic glucocorticoid therapy in infants with hemangiomas. Arch Dermatol. 2009 Mar;145(3):262-6. Abstract

62. Chantharatanapiboon W. Intralesional corticosteroid therapy in hemangiomas: clinical outcome in 160 cases. J Med Assoc Thai. 2008 Oct;91(suppl 3):S90-6. Abstract

63. Chen MT, Yeong EK, Horng SY. Intralesional corticosteroid therapy in proliferating head and neck hemangiomas: a review of 155 cases. J Pediatr Surg. 2000 Mar;35(3):420-3. Abstract

64. Buckmiller LM, Francis CL, Glade RS. Intralesional steroid injection for proliferative parotid hemangiomas. Int J Pediatr Otorhinolaryngol. 2008 Jan;72(1):81-7. Abstract

65. Sinno H, Thibaudeau S, Coughlin R, et al. Management of infantile parotid gland hemangiomas: a 40-year experience. Plast Reconstr Surg. 2010 Jan;125(1):265-73. Abstract

66. Batta K, Goodyear HM, Moss C, et al. Randomised controlled study of early pulsed dye laser treatment of uncomplicated childhood haemangiomas: results of a 1-year analysis. Lancet. 2002 Aug 17;360(9332):521-7. Abstract

67. Stier MF, Click SA, Hirsch RJ. Laser treatment of pediatric vascular lesions: port-wine stains and hemangiomas. J Am Acad Dermatol. 2008 Feb;58(2):261-85. Abstract

68. Smit JM, Bauland CG, Wijnberg DS, et al. Pulsed dye laser treatment, a review of indications and outcome based on published trials. Br J Plast Surg. 2005 Oct;58(7):981-7. Abstract

69. Brightman LA, Brauer JA, Terushkin V, et al. Ablative fractional resurfacing for involuted hemangioma residuum. Arch Dermatol. 2012 Nov;148(11):1294-8.Full text  Abstract

70. Brandling-Bennett HA, Metry DW, Baselga E, et al. Infantile hemangiomas with unusually prolonged growth phase: a case series. Arch Dermatol. 2008 Dec;144(12):1632-7. Abstract

71. Li G, Xu D, Hu Z, et al. Embolic retinal and choroidal vascular occlusion after peribulbar triamcinolone injection: a case report. Medicine (Baltimore). 2018 Apr;97(17):e0467.Full text  Abstract

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