Motion sickness

Cha YH, Golding JF, Keshavarz B, et al. Motion sickness diagnostic criteria: consensus document of the Classification Committee of the Bárány Society. J Vestib Res. 2021;31(5):327-44.Full text  Abstract

Centers for Disease Control and Prevention. CDC Yellow Book 2024: health information for international travel. Section 8: Travel by air, land & sea - motion sickness. May 2023 [internet publication].Full text

Spinks AB, Wasiak J. Scopolamine (hyoscine) for preventing and treating motion sickness. Cochrane Database Syst Rev. 2011;(6):CD002851.Full text  Abstract

1. Cha YH, Golding JF, Keshavarz B, et al. Motion sickness diagnostic criteria: consensus document of the Classification Committee of the Bárány Society. J Vestib Res. 2021;31(5):327-44.Full text  Abstract

2. Reason JT, Graybiel A. Changes in subjective estimates of well-being during the onset and remission of motion sickness symptomatology in the slow rotation room. Aerosp Med. 1970 Feb;41(2):166-71.

3. Hu S, Grant WF, Stern RM, et al. Motion sickness severity and physiological correlates during repeated exposures to a rotating optokinetic drum. Aviat Space Environ Med. 1991;62:308-314. Abstract

4. Guerraz M, Yardley L, Bertholon P, et al. Visual vertigo: symptom assessment, spatial orientation and postural control. Brain. 2001;124:1646-56.Full text  Abstract

5. Stanney KM, Hale KS, Nahmens I, et al. What to expect from immersive virtual environment exposure: influences of gender, body mass index, and past experience. Hum Factors. 2003;45:504-520. Abstract

6. Kennedy RS, Fowlkes JE. Simulator sickness is polygenic and polysymptomatic: implications for research. Int J Aviat Psychol. 1992;2:23-38.

7. Kennedy R, Lane N, Lilienthal M, et al. Profile analysis of simulator sickness symptoms: application to virtual reality environments. Presence. 1992;1:295-301.

8. Golding JF, Stott JR. Effect of sickness severity on habituation to repeated motion challenges in aircrew referred for airsickness treatment. Aviat Space Environ Med. 1995;66:625-630. Abstract

9. Centers for Disease Control and Prevention. CDC Yellow Book 2024: health information for international travel. Section 8: Travel by air, land & sea - motion sickness. May 2023 [internet publication].Full text

10. Bronstein AM, Golding JF, Gresty MA. Visual vertigo, motion sickness, and disorientation in vehicles. Semin Neurol. 2020 Feb;40(1):116-29. Abstract

11. Keshavarz B, Golding JF. Motion sickness: current concepts and management. Curr Opin Neurol. 2022 Feb 1;35(1):107-12. Abstract

12. Turner M, Griffin MJ. Motion sickness in public road transport: passenger behavior and susceptibility. Ergonomics. 1999;42:444-461. Abstract

13. Flanagan MB, May JG, Dobie TG. Sex differences in tolerance to visually-induced motion sickness. Aviat Space Environ Med. 2005;76:642-46. Abstract

14. Kennedy RS, Lanham DS, Massey CJ, et al. Gender differences in simulator sickness incidence: implications for military virtual reality systems. Safe J. 1995;25:69-76.

15. Klosterhalfen S, Kellermann S, Pan F, et al. Effects of ethnicity and gender on motion sickness susceptibility. Aviat Space Environ Med. 2005;76:1051-1057. Abstract

16. Lawther A, Griffin MJ. A survey of the occurrence of motion sickness amongst passengers at sea. Aviat Space Environ Med. 1988;59:399-406. Abstract

17. Stern RM, Hu S, LeBlanc R, et al. Chinese hyper-susceptibility to vection-induced motion sickness. Aviat Space Environ Med. 1993;64: 827-830. Abstract

18. Zhang LL, Wang JQ, Qi RR, et al. Motion sickness: current knowledge and recent advance. CNS Neurosci Ther. 2016 Jan;22(1):15-24. Abstract

19. Golding JF, Mueller AG, Gresty MA. A motion sickness maximum around the 0.2 Hz frequency range of horizontal translational oscillation. Aviat Space Environ Med. 2001;72:188-192. Abstract

20. Lawther A, Griffin MJ. Prediction of the incidence of motion sickness from the magnitude, frequency, and duration of vertical oscillation. J Acoust Soc Am. 1987;82:957-966. Abstract

21. O'Hanlon JF, McCauley ME. Motion sickness incidence as a function of the frequency and acceleration of vertical sinusoidal motion. Aerosp Med. 1974;45:366-369. Abstract

22. Bijveld MM, Bronstein AM, Golding JF, et al. Nauseogenicity of off-vertical axis rotation vs. equivalent visual motion. Aviat Space Environ Med. 2008;79:661-665. Abstract

23. Drummond PD. Triggers of motion sickness in migraine sufferers. Headache. 2005;45:653-656. Abstract

24. Huang TC, Wang SJ, Kheradmand A. Vestibular migraine: an update on current understanding and future directions. Cephalalgia. 2020 Jan;40(1):107-21.Full text  Abstract

25. Arshad Q, Moreno-Ajona D, Goadsby PJ, et al. What visuospatial perception has taught us about the pathophysiology of vestibular migraine. Curr Opin Neurol. 2024 Feb 1;37(1):32-9. Abstract

26. Stern RM, Koch KL, Stewart WR, et al. Spectral analysis of tachygastria recorded during motion sickness. Gastroenterol. 1987;92:92-97. Abstract

27. Neimer J, Eskiizmirliler S, Ventre-Dominey J, et al. Trains with a view to sickness. Curr Biol. 2001;11:R549-R550. Abstract

28. Williamson MJ, Thomas MJ, Stern RM. The contribution of expectations to motion sickness symptoms and gastric activity. Psychosom Res. 2004;56:721-6. Abstract

29. Houchens PW, Jones MB. Behavioral contagion in an experimental motion environment. Aviat Space Environ Med. 2003;74:649-653. Abstract

30. Zajonc TP, Roland PS. Vertigo and motion sickness. Part II: Pharmacologic treatment. Ear Nose Throat J. 2006;85:25-35. Abstract

31. Zajonc TP, Roland PS. Vertigo and motion sickness. Part I: vestibular anatomy and physiology. Ear Nose Throat J. 2005;84:581-584. Abstract

32. Ventre-Dominey J, Luyat M, Denise P, et al. Motion sickness induced by otolith stimulation is correlated with otolith-induced eye movements. Neuroscience. 2008;155:771-779. Abstract

33. Dai M, Kunin M, Raphan T, et al. The relation of motion sickness to the spatial-temporal properties of velocity storage. Exp Brain Res. 2003;151:173-189. Abstract

34. Cohen B, Dai M, Yakushin SB, et al. Baclofen, motion sickness susceptibility and the neural basis for velocity storage. Prog Brain Res. 2008;171:543-553. Abstract

35. Dai M, Sofroniou S, Kunin M, et al. Motion sickness induced by off-vertical axis rotation (OVAR). Exp Brain Res. 2010 Jul;204(2):207-22. Abstract

36. Stern RM, Leibowitz HW, Unblad I, et al. Tachygastria and motion sickness. Aviat Space Environ Med. 1985;56:1074-1077. Abstract

37. Drummond PD. Effect of tryptophan depletion on symptoms of motion sickness in migraineurs. Neurology. 2005;65:620-622. Abstract

38. von Reinhart J. Histamin-intoleranz: histamin und seekrankheit. Stuttgart: Thieme; 2004.

39. Lichtenberg BK, Young LR, Arrott AP. Human ocular counterrolling induced by varying linear accelerations. Exp Brain Res. 1982;48:127-136. Abstract

40. Merfeld DM, Park S, Gianna-Poulin C, et al. Vestibular perception and action employ qualitatively different mechanisms. II. VOR and perceptual responses during combined Tilt&Translation. J Neurophysiol. 2005;94:199-205.Full text  Abstract

41. Merfeld DM, Park S, Gianna-Poulin C, et al. Vestibular perception and action employ qualitatively different mechanisms. I. Frequency response of VOR and perceptual responses during Translation and Tilt. J Neurophysiol. 2005;94:186-198.Full text  Abstract

42. Wood SJ. Human otolith-ocular reflexes during off-vertical axis rotation: effect of frequency on tilt-translation ambiguity and motion sickness. Neurosci Lett. 2002;323:41-44. Abstract

43. Kheradmand A, Winnick A. Perception of upright: multisensory convergence and the role of temporo-parietal cortex. Front Neurol. 2017;8:552.Full text  Abstract

44. Money KE, Cheung BS. Another function of the inner ear: facilitation of the emetic response to poisons. Aviat Space Environ Med. 1983;54:208-211. Abstract

45. Treisman M. Motion sickness: an evolutionary hypothesis. Science. 1977;197:493-495. Abstract

46. Yates BJ, Miller AD, Lucot JB. Physiological basis and pharmacology of motion sickness: an update. Brain Res Bull. 1998;47:395-406. Abstract

47. Reavley CM, Golding JF, Cherkas LF, et al. Genetic influences on motion sickness susceptibility in adult women: a classical twin study. Aviat Space Environ Med. 2006 Nov;77(11):1148-52.Full text  Abstract

48. Drummond PD, Granston A. Facial pain increases nausea and headache during motion sickness in migraineurs. Brain. 2004;127:526-534. Abstract

49. Murdin L, Chamberlain F, Cheema S, et al. Motion sickness in migraine and vestibular disorders. J Neurol Neurosurg Psychiatry. 2015 May;86(5):585-7.Full text

50. Pavlou M, Lingeswaran A, Davies RA, et al. Simulator based rehabilitation in refractory dizziness. J Neurol. 2004;251:983-95. Abstract

51. Takahashi M, Okada Y, Saito A, et al. Locomotion and motion sickness under horizontal and vertical reversal of vision. Acta Otolaryngol Suppl. 1991;481:319-21.

52. Lee SH, Kim M, Kim H, et al. Visual fatigue induced by watching virtual reality device and the effect of anisometropia. Ergonomics. 2021 Dec;64(12):1522-31. Abstract

53. Golding JF, Prosyanikova O, Flynn M, et al. The effects of smoking nicotine tobacco versus smoking deprivation on motion sickness. Aviat Space Environ Med. 2008;79:262.

54. Redfern MS, Furman JM, Jacob RG. Visually induced postural sway in anxiety disorders. J Anxiety Disord. 2007;21:704-716.Full text  Abstract

55. Redfern MS, Yardley L, Bronstein AM. Visual influences on balance. J Anxiety Disord. 2001;15:81-94. Abstract

56. Romas RT, Jacob RG, Lilienfeld SO. Space and motion discomfort in Brazilian versus American patients with anxiety disorders. J Anxiety Disord. 1997;11:131-139. Abstract

57. Golding JF, Kadzere P, Gresty MA. Motion sickness susceptibility fluctuates through the menstrual cycle. Aviat Space Environ Med. 2005:76; 970-973. Abstract

58. Saman Y, Sharif M, Lee A, et al. Sex-disease dimorphism underpins enhanced motion sickness susceptibility in primary adrenal insufficiency: a cross-sectional observational study. Exp Brain Res. 2023 Apr;241(4):1199-206. Abstract

59. Stern RM, Hu S, Anderson RB, et al. The effects of fixation and restricted visual field on vection-induced motion sickness. Aviat Space Environ Med. 1990;61:712-715. Abstract

60. Streitberger K, Ezzo J, Schneider A. Acupuncture for nausea and vomiting: an update of clinical and experimental studies. Auton Neurosci. 2006;129:107-17. Abstract

61. Hu S, Stern RM, Koch KL. Electrical acustimulation relieves vection-induced motion sickness. Gastroenterology. 1992;102:1854-8. Abstract

62. Denise P, Vouriot A, Normand H, et al. Effect of temporal relationship between respiration and body motion on motion sickness. Auton Neurosci. 2009;151:142-6. Abstract

63. Golding JF. Predicting individual differences in motion sickness susceptibility by questionnaire. Pers Individ Dif. 2006;41:237-248.

64. Jokerst MD, Gatto M, Fazio R, et al. Slow deep breathing prevents the development of tachygastria and symptoms of motion sickness. Aviat Space Environ Med. 1999;70:1189-1192. Abstract

65. Yen Pik Sang F, Billar JP, Gresty MA, et al. Effect of a novel motion desensitization training regime and controlled breathing on habituation to motion sickness. Percept Mot Skills. 2005;101:244-256. Abstract

66. Yen Pik Sang FD, Billar JP, Golding JF, et al. Behavioral methods of alleviating motion sickness: effectiveness of controlled breathing and a music audiotape. J Travel Med. 2003;10:108-11.Full text  Abstract

67. Yen Pik Sang FD, Golding JF, Gresty MA. Suppression of sickness by controlled breathing during mildly nauseogenic motion. Aviat Space Environ Med. 2003;74:998-1002. Abstract

68. Fiori F, David N, Aglioti SM. Processing of proprioceptive and vestibular body signals and self-transcendence in Ashtanga yoga practitioners. Front Hum Neurosci. 2014 Sep 18:8:734.Full text  Abstract

69. Nigmatullina Y, Hellyer PJ, Nachev P, et al. The neuroanatomical correlates of training-related perceptuo-reflex uncoupling in dancers. Cereb Cortex. 2015 Feb;25(2):554-62.Full text  Abstract

70. Wood CD, Graybiel A. Evaluation of 16 antimotion sickness drugs under controlled laboratory conditions. Aerospace Med. 1968;39:1341-1344.

71. Spinks AB, Wasiak J. Scopolamine (hyoscine) for preventing and treating motion sickness. Cochrane Database Syst Rev. 2011;(6):CD002851.Full text  Abstract

72. Burton MJ, Roland PS, Rosenfeld RM. Extracts from The Cochrane Library: Scopolamine (hyoscine) for preventing and treating motion sickness. Otolaryngol Head Neck Surg. 2010;142:468-471. Abstract

73. Karrim N, Byrne R, Magula N, et al. Antihistamines for motion sickness. Cochrane Database Syst Rev. 2022 Oct 17;10(10):CD012715.Full text  Abstract

74. Stewart JJ, Wood MJ, Parish RC, et al. Prokinetic effects of erythromycin after antimotion sickness drugs. J Clin Pharmacol. 2000;40:347-353. Abstract

75. Bar R, Gil A, Tal D. Safety of double-dose transdermal scopolamine. Pharmacotherapy. 2009;29:1082-1088. Abstract

76. Howland J, Rohsenow DJ, Minsky S, et al. The effects of transdermal scopolamine on simulated ship navigation and attention/reaction time. Int J Occup Environ Health. 2008;14:250-256. Abstract

77. Cowings PS, Toscano WB. Autogenic-feedback training exercise is superior to promethazine for control of motion sickness symptoms. J Clin Pharmacol. 2000;40:1154-65. Abstract

78. Golding JF, Stott JR. Objective and subjective time courses of recovery from motion sickness assessed by repeated motion challenges. J Vestib Res. 1997;7:421-428. Abstract

79. Stern RM, Hu SQ, Vasey MW, et al. Adaptation to vection-induced symptoms of motion sickness. Aviat Space Environ Med. 1989 Jun;60(6):566-72.Full text  Abstract

80. Ressiot E, Dolz M, Bonne L, et al. Prospective study on the efficacy of optokinetic training in the treatment of seasickness. Eur Ann Otorhinolaryngol Head Neck Dis. 2013;130:263-268. Abstract

81. Stroud KJ, Harm DL, Klaus DM. Preflight virtual reality training as a countermeasure for space motion sickness and disorientation. Aviat Space Environ Med. 2005;76:352-356. Abstract

82. Dobie TG, May JG. Cognitive-behavioural management of motion sickness. Aviat Space Environ Med. 1994;65:C1-C2. Abstract

83. Toscano WB, Cowings PS. Reducing motion sickness: a comparison of autogenic-feedback training and an alternative cognitive task. Aviat Space Environ Med. 1982;53:449-453. Abstract

84. Javid FA, Naylor RJ. The effect of serotonin and serotonin receptor antagonists on motion sickness in Suncus murinus. Pharmacol Biochem Behav. 2002;73:979-989. Abstract

85. Marcus DA, Furman JM. Prevention of motion sickness with rizatriptan: a double-blind, placebo-controlled pilot study. Med Sci Monit. 2006;12:PI1-PI7. Abstract

86. Furman JM, Marcus DA, Balaban CD. Rizatriptan reduces vestibular-induced motion sickness in migraineurs. J Headache Pain. 2011 Feb;12(1):81-8.Full text  Abstract

87. Klocker N, Hanschke W, Toussaint S, et al. Scopolamine nasal spray in motion sickness: a randomised, controlled, and crossover study for the comparison of two scopolamine nasal sprays with oral dimenhydrinate and placebo. Eur J Pharm Sci. 2001;13:227-232. Abstract

88. Ahmed S, Sileno AP, de Meireles JC, et al. Effects of pH and dose on nasal absorption of scopolamine hydrobromide in human subjects. Pharm Res. 2000;17:974-977. Abstract

89. Simmons RG, Phillips JB, Lojewski RA, et al. The efficacy of low-dose intranasal scopolamine for motion sickness. Aviat Space Environ Med. 2010;81:405-412. Abstract

90. Stankovic AS, Alvarenga DL, Coleman Daniels VR, et al. Intranasal scopolamine for motion sickness. Aerosp Med Hum Perform. 2019 Nov 1;90(11):917-24.Full text  Abstract

91. Yang M, Li Z, Pan F, et al. Alpha tACS on parieto-occipital cortex mitigates motion sickness based on multiple physiological observation. IEEE Trans Neural Syst Rehabil Eng. 2024;32:2398-407.Full text  Abstract

92. Li G, Zanto T. Reduced VR motion sickness by applying random-phase transcranial alternating current stimulation to the left parietal cortex. Brain Stimul. 2024 May-Jun;17(3):550-2.Full text

93. Takeuchi N, Mori T, Suzukamo Y, et al. Modulation of excitability in the temporoparietal junction relieves virtual reality sickness. Cyberpsychol Behav Soc Netw. 2018 Jun;21(6):381-7. Abstract

94. Arshad Q, Cerchiai N, Goga U, et al. Electrocortical therapy for motion sickness. Neurology. 2015 Oct 6;85(14):1257-9.Full text

95. Grunfeld E, Price C, Goadsby P, et al. Migraine, motion sickness and menstruation in mariners. Lancet. 1998;351:1106. Abstract