Cerumen impaction

Schwartz SR, Magit AE, Rosenfeld RM, et al. Clinical practice guideline (update): earwax (cerumen impaction). Otolaryngol Head Neck Surg. 2017 Jan;156(1_suppl):S1-29.Full text  Abstract

Roeser RJ, Ballachanda BB. Physiology, pathophysiology, and anthropology/epidemiology of human ear canal secretions. J Am Acad Audiol. 1997 Dec;8(6):391-400. Abstract

Horton GA, Simpson MTW, Beyea MM, et al. Cerumen management: an updated clinical review and evidence-based approach for primary care physicians. J Prim Care Community Health. 2020 Jan-Dec;11:2150132720904181.Full text  Abstract

Roland PS, Eaton DA, Gross RD, et al. Randomized, placebo-controlled evaluation of Cerumenex and murine earwax removal products. Arch Otolaryngol Head Neck Surg. 2004 Oct;130(10):1175-7.Full text  Abstract

Aaron K, Cooper TE, Warner L, et al. Ear drops for the removal of ear wax. Cochrane Database Syst Rev. 2018 Jul 25;(7):CD012171.Full text  Abstract

1. Schwartz SR, Magit AE, Rosenfeld RM, et al. Clinical practice guideline (update): earwax (cerumen impaction). Otolaryngol Head Neck Surg. 2017 Jan;156(1_suppl):S1-29.Full text  Abstract

2. Roeser RJ, Ballachanda BB. Physiology, pathophysiology, and anthropology/epidemiology of human ear canal secretions. J Am Acad Audiol. 1997 Dec;8(6):391-400. Abstract

3. Yoshiura K, Kinoshita A, Ishida T, et al. A SNP in the ABCC11 gene is the determinant of human earwax type. Nat Genet. 2006 Mar;38(3):324-30. Abstract

4. Horton GA, Simpson MTW, Beyea MM, et al. Cerumen management: an updated clinical review and evidence-based approach for primary care physicians. J Prim Care Community Health. 2020 Jan-Dec;11:2150132720904181.Full text  Abstract

5. Guest JF, Greener MJ, Robinson AC, et al. Impacted cerumen: composition, production, epidemiology and management. QJM. 2004 Aug;97(8):477-88.Full text  Abstract

6. Tomita H, Yamada K, Ghadami M, et al. Mapping of the wet/dry earwax locus to the pericentromeric region of chromosome 16. Lancet. 2002 Jun 8;359(9322):2000-2. Abstract

7. Shott SR. Down syndrome: common otolaryngologic manifestations. Am J Med Genet C Semin Med Genet. 2006 Aug 15;142C(3):131-40.Full text  Abstract

8. Freeman RB. Impacted cerumen: how to safely remove earwax in an office visit. Geriatrics. 1995 Jun;50(6):52-3. Abstract

9. Coppin R, Wicke D, Little P. Managing earwax in primary care: efficacy of self-treatment using a bulb syringe. Br J Gen Pract. 2008 Jan;58(546):44-9.Full text  Abstract

10. Coppin R, Wicke D, Little P. Randomized trial of bulb syringes for earwax: impact on health service utilization. Ann Fam Med. 2011 Mar-Apr;9(2):110-4.Full text  Abstract

11. Hand C, Harvey I. The effectiveness of topical preparations for the treatment of earwax: a systematic review. Br J Gen Pract. 2004 Nov;54(508):862-7.Full text  Abstract

12. Roland PS, Eaton DA, Gross RD, et al. Randomized, placebo-controlled evaluation of Cerumenex and murine earwax removal products. Arch Otolaryngol Head Neck Surg. 2004 Oct;130(10):1175-7.Full text  Abstract

13. Aaron K, Cooper TE, Warner L, et al. Ear drops for the removal of ear wax. Cochrane Database Syst Rev. 2018 Jul 25;(7):CD012171.Full text  Abstract

14. Rubin J, Yu VL, Kamerer DB, et al. Aural irrigation with water: a potential pathogenic mechanism for inducing malignant external otitis? Ann Otol Rhinol Laryngol. 1990 Feb;99(2 Pt 1):117-9. Abstract

15. Zikk D, Rapoport Y, Himelfarb MZ. Invasive external otitis after removal of impacted cerumen by irrigation. N Engl J Med. 1991 Sep 26;325(13):969-70. Abstract

16. Seely DR, Quigley SM, Langman AW. Ear candles - efficacy and safety. Laryngoscope. 1996 Oct;106(10):1226-9. Abstract

17. Food and Drug Administration. Detention without physical examination of ear candles. Center for Devices and Radiological Health. June 2013 [internet publication].Full text

18. Driscoll PV, Ramachandrula A, Drezner DA, et al. Characteristics of cerumen in diabetic patients: a key to understanding malignant external otitis. Otolaryngol Head Neck Surg. 1993 Oct;109(4):676-9. Abstract