In its mildest form, serotonin toxicity is probably relatively common but is often unreported.[2][3][8][9] In addition, the ambiguous nature of the Sternbach criteria,[10] a set of criteria that has been used to define serotonin toxicity for many years, means that many other medical conditions were often misdiagnosed as serotonin toxicity, despite the second part of the Sternbach criteria requiring the absence of other causes.[3][11]

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