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Functional neurologic and somatic symptom disorders

最后审阅: 11 Dec 2025
最后更新: 28 Nov 2023

小结

定义

病史和体格检查

关键诊断因素

  • unconventional behavior during history
  • emotional processing problems
  • recent psychological or physical stressors
  • remote life stressors
  • multiple illness behaviors
  • unusual neurologic deficits
  • give-way weakness
  • inconsistent examination findings
  • paradoxical sensory findings
  • distractible symptoms
  • generalized seizure-like motor movements without loss of awareness
  • gait disorders
  • functional movement disorders
完整详情

其他诊断因素

  • cognitive complaints
  • Hoover sign
  • speech disturbance
  • swallowing disturbance
  • pseudoclonus
  • convergence spasm
完整详情

危险因素

  • history of sexual or physical abuse
  • adverse childhood events
  • history of trauma-related disorders
  • female sex
  • alexithymia
  • neuroticism
  • previously poor doctor-patient relationships
完整详情

诊断性检查

首要检查

  • laboratory testing
  • electroencephalogram (EEG)
完整详情

需考虑的检查

  • comprehensive neuropsychological testing
  • standardized personality testing
  • focused symptom inventories
完整详情

治疗流程

急症处理

functional neurologic disorder

somatic symptom disorder

撰稿人

作者

Cynthia M. Stonnington, MD
Cynthia M. Stonnington

Professor of Psychiatry

Mayo Clinic

Scottsdale

AZ

利益声明

CMS is an author of a number of references cited in this topic.

Erika Driver-Dunckley, MD
Erika Driver-Dunckley

Professor of Neurology

Mayo Clinic

Scottsdale

AZ

利益声明

EDD declares that she has no competing interests.

Katherine H. Noe, MD, PhD
Katherine H. Noe

Associate Professor of Neurology

Mayo Clinic

Scottsdale

AZ

利益声明

KHN declares that she has no competing interests.

Dona Locke, PhD
Dona Locke

Professor of Psychology

Mayo Clinic

Scottsdale

AZ

利益声明

DL declares that she has no competing interests.

同行评议者

David Perez, MD, MMSc

Psychiatrist and Assistant Neurologist

Massachusetts General Hospital

Associate Professor of Neurology and Psychiatry

Harvard Medical School

Boston

MA

利益声明

DLP has received honoraria for continuing medical education lectures in functional neurologic disorder, research funding for the NH and Sidney R. Baer Jr. Foundation, and royalties from Springer Nature for a textbook on functional movement disorder. DLP has also previously published with the BMJ and is on the editorial board of Epilepsy & Behavior. DLP is the author of a number of papers cited in this topic.

James L Levenson, MD

Rhona Arenstein Professor of Psychiatry

Virginia Commonwealth University

Virginia

利益声明

JLL declares that he was the unpaid text editor for the sections of DSM 5 and DSM 5-TR covering the two diagnoses listed in the topic.

Anton Scamvougeras, MBChB, FRCP

Consultant Neuropsychiatrist and Associate Clinical Professor

Department of Psychiatry

University of British Columbia

Vancouver

British Columbia

Canada

利益声明

AS declares that he has no competing interests. AS is the author of one paper cited in the topic.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

参考文献

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

关键文献

Perez DL, Aybek S, Popkirov S, et al; American Neuropsychiatric Association Committee on Research. A review and expert opinion on the neuropsychiatric assessment of motor functional neurological disorders. J Neuropsychiatry Clin Neurosci. 2021 Winter;33(1):14-26.全文  摘要

Löwe B, Levenson J, Depping M, et al. Somatic symptom disorder: a scoping review on the empirical evidence of a new diagnosis. Psychol Med. 2022 Mar;52(4):632-48.全文  摘要

Stone J, Burton C, Carson A. Recognising and explaining functional neurological disorder. BMJ. 2020 Oct 21;371:m3745.

Bennett K, Diamond C, Hoeritzauer I, et al. A practical review of functional neurological disorder (FND) for the general physician. Clin Med (Lond). 2021 Jan;21(1):28-36.全文  摘要

Baslet G, Bajestan SN, Aybek S, et al. Evidence-based practice for the clinical assessment of psychogenic nonepileptic seizures: a report from the American Neuropsychiatric Association Committee on Research. J Neuropsychiatry Clin Neurosci. 2021 Winter;33(1):27-42.全文  摘要

den Boeft M, Claassen-van Dessel N, van der Wouden JC. How should we manage adults with persistent unexplained physical symptoms? BMJ. 2017 Feb 8;356:j268. 摘要

Henningsen P, Zipfel S, Herzog W. Management of functional somatic syndromes. Lancet. 2007 Mar 17;369(9565):946-55. 摘要

参考文献

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
  • Functional neurologic and somatic symptom disorders images
  • 鉴别诊断

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    • Body dysmorphic disorder
    • Factitious disorder
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  • 指南

    • A review and expert opinion on the neuropsychiatric assessment of motor functional neurological disorders
    • Evidence-based practice for the clinical assessment of psychogenic nonepileptic seizures
    更多 指南
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