Frontotemporal dementia

References

Key articles

Rascovsky K, Hodges JR, Knopman D, et al. Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Brain. 2011 Sep;134(Pt 9):2456-77.Full text  Abstract

Rascovsky K, Hodges JR, Knopman D, et al. Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Brain. 2011 Sep;134(Pt 9):2456-77.Full text  Abstract

Moore KM, Nicholas J, Grossman M, et al. Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study. Lancet Neurol. 2020 Feb;19(2):145-56.Full text  Abstract

Mackenzie IR, Neumann M. Molecular neuropathology of frontotemporal dementia: insights into disease mechanisms from postmortem studies. J Neurochem. 2016 Aug;138(suppl 1):54-70.Full text  Abstract

NHMRC Partnership Centre for Dealing with Cognitive and Related Functional Decline in Older People. Clinical practice guidelines and principles of care for people with dementia. Feb 2016 [internet publication].Full text

Dyer SM, Harrison SL, Laver K, et al. An overview of systematic reviews of pharmacological and non-pharmacological interventions for the treatment of behavioral and psychological symptoms of dementia. Int Psychogeriatr. 2018 Mar;30(3):295-309.Full text  Abstract

Buoli M, Serati M, Caldiroli A, et al. Pharmacological management of psychiatric symptoms in frontotemporal dementia: a systematic review. J Geriatr Psychiatry Neurol. 2017 May;30(3):162-9. Abstract

Trieu C, Gossink F, Stek ML, et al. Effectiveness of pharmacological interventions for symptoms of behavioral variant frontotemporal dementia: a systematic review. Cogn Behav Neurol. 2020 Mar;33(1):1-15. Abstract

Reference articles

1. Ratnavalli E, Brayne C, Dawson K, et al. The prevalence of frontotemporal dementia. Neurology. 2002 Jun 11;58(11):1615-21. Abstract

2. Rosso SM, Donker Kaat L, Baks T, et al. Frontotemporal dementia in the Netherlands: patient characteristics and prevalence estimates from a population-based study. Brain. 2003 Sep;126(Pt 9):2016-22.Full text  Abstract

3. Johnson JK, Diehl J, Mendez MF, et al. Frontotemporal lobar degeneration: demographic characteristics of 353 patients. Arch Neurol. 2005 Jun;62(6):925-30.Full text  Abstract

4. Coyle-Gilchrist IT, Dick KM, Patterson K, et al. Prevalence, characteristics, and survival of frontotemporal lobar degeneration syndromes. Neurology. 2016 May 3;86(18):1736-43.Full text  Abstract

5. Piguet O, Hornberger M, Mioshi E, et al. Behavioral-variant frontotemporal dementia: diagnosis, clinical staging and management. Lancet Neurol. 2011 Feb;10(2):162-72. Abstract

6. Neary D, Snowden JS, Gustafson L, et al. Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. Neurology. 1998 Dec;51(6):1546-54. Abstract

7. Gorno-Tempini ML, Hillis AE, Weintraub S, et al. Classification of primary progressive aphasia and its variants. Neurology. 2011 Mar 15;76(11):1006-14.Full text  Abstract

8. Josephs KA. Frontotemporal dementia and related disorders: deciphering the enigma. Ann Neurol. 2008 Jul;64(1):4-14. Abstract

9. Rascovsky K, Hodges JR, Knopman D, et al. Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Brain. 2011 Sep;134(Pt 9):2456-77.Full text  Abstract

10. Harris JM, Gall C, Thompson JC, et al. Sensitivity and specificity of FTDC criteria for behavioral variant frontotemporal dementia. Neurology. 2013 May 14;80(20):1881-7. Abstract

11. Warren JD, Rohrer JD, Rossor MN. Clinical review. Frontotemporal dementia. BMJ. 2013 Aug 6;347:f4827.Full text  Abstract

12. Feldman H, Levy AR, Hsiung GY, et al. A Canadian cohort study of cognitive impairment and related dementias (ACCORD): study methods and baseline results. Neuroepidemiology. 2003 Sep-Oct;22(5):265-74. Abstract

13. Stephan BC, Minett T, Pagett E, et al. Diagnosing mild cognitive impairment (MCI) in clinical trials: a systematic review. BMJ Open. 2013 Feb 4;3(2).Full text  Abstract

14. Bernardi L, Frangipane F, Smirne N, et al. Epidemiology and genetics of frontotemporal dementia: a door-to-door survey in Southern Italy. Neurobiol Aging. 2012 Dec;33(12):2948.Full text  Abstract

15. Diehl-Schmid J, Schūlte-Overberg J, Hartmann J, et al. Extrapyramidal signs, primitive reflexes and incontinence in fronto-temporal dementia. Eur J Neurol. 2007 Aug;14(8):860-4. Abstract

16. Bang J, Spina S, Miller BL. Frontotemporal dementia. Lancet. 2015 Oct 24;386(10004):1672-82.Full text  Abstract

17. Mackenzie IR, Neumann M, Bigio EH, et al. Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update. Acta Neuropathol. 2010 Jan;119(1):1-4.Full text  Abstract

18. Rascovsky K, Hodges JR, Knopman D, et al. Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Brain. 2011 Sep;134(Pt 9):2456-77.Full text  Abstract

19. American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 5th ed., text revision (DSM-5-TR). Washington, DC: American Psychiatric Publishing; 2022.Full text

20. American Psychiatric Association. DSM-5-TR neurocognitive disorders supplement. Updated excerpts for delirium codes major and mild neurocognitive disorders. October 2022.Full text

21. Hogan DB, Jetté N, Fiest KM, et al. The prevalence and incidence of frontotemporal dementia: a systematic review. Can J Neurol Sci. 2016 Apr;43 Suppl 1:S96-S109.Full text  Abstract

22. Knopman DS, Mastri AR, Frey WH 2nd, et al. Dementia lacking distinctive histologic features: a common non-Alzheimer degenerative dementia. Neurology. 1990 Feb;40(2):251-6. Abstract

23. Barker WW, Luis CA, Kashuba A, et al. Relative frequencies of Alzheimer disease, Lewy body, vascular and frontotemporal dementia, and hippocampal sclerosis in the State of Florida Brain Bank. Alzheimer Dis Assoc Disord. 2002 Oct-Dec;16(4):203-12. Abstract

24. Ducharme S, Dols A, Laforce R, et al. Recommendations to distinguish behavioural variant frontotemporal dementia from psychiatric disorders. Brain. 2020 Jun 1;143(6):1632-50.Full text  Abstract

25. Baborie A, Griffiths TD, Jaros E, et al. Frontotemporal dementia in elderly individuals. Arch Neurol. 2012 Aug;69(8):1052-60. Abstract

26. Moore KM, Nicholas J, Grossman M, et al. Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study. Lancet Neurol. 2020 Feb;19(2):145-56.Full text  Abstract

27. Gilberti N, Turla M, Alberici A, et al. Prevalence of frontotemporal lobar degeneration in an isolated population: the Vallecamonica study. Neurol Sci. 2012 Aug;33(4):899-904. Abstract

28. Hou CE, Yaffe K, Pérez-Stable EJ, et al. Frequency of dementia etiologies in four ethnic groups. Dement Geriatr Cogn Disord. 2006;22(1):42-7. Abstract

29. Rohrer JD, Guerriro R, Vandrocova J, et al. The hereditability and genetics of frontotemporal lobar degeneration. Neurology. 2009 Nov 3;73(18):1451-6.Full text  Abstract

30. Greaves CV, Rohrer JD. An update on genetic frontotemporal dementia. J Neurol. 2019 Aug;266(8):2075-86.Full text  Abstract

31. Wood EM, Falcone D, Suh E, et al. Development and validation of pedigree classification criteria for frontotemporal lobar degeneration. JAMA Neurol. 2013 Nov;70(11):1411-7.Full text  Abstract

32. Hutton M, Lendon CL, Rizzu P, et al. Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17. Nature. 1998 Jun 18;393(6686):702-5. Abstract

33. Baker M, Mackenzie IR, Pickering-Brown SM, et al. Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17. Nature. 2006 Aug 24;442(7105):916-9. Abstract

34. Cruts M, Gijselinck I, van der Zee J, et al. Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21. Nature. 2006 Aug 24;442(7105):920-4. Abstract

35. DeJesus-Hernandez M, Mackenzie IR, Boeve BF, et al. Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. Neuron. 2011 Oct 20;72(2):245-56.Full text  Abstract

36. Byrne S, Elamin M, Bede P, et al. Cognitive and clinical characteristics of patients with amyotrophic lateral sclerosis carrying a C9orf72 repeat expansion: a population-based cohort study. Lancet Neurol. 2012 Mar;11(3):232-40.Full text  Abstract

37. Balendra R, Isaacs AM. C9orf72-mediated ALS and FTD: multiple pathways to disease. Nat Rev Neurol. 2018 Sep;14(9):544-58.Full text  Abstract

38. Mol MO, van Rooij JGJ, Wong TH, et al. Underlying genetic variation in familial frontotemporal dementia: sequencing of 198 patients. Neurobiol Aging. 2021 Jan;97:148.e9-148.e16.Full text  Abstract

39. Borroni B, Bonvicini C, Galimberti D, et al. Founder effect and estimation of the age of the Progranulin Thr272fs mutation in 14 Italian pedigrees with frontotemporal lobar degeneration. Neurobiol Aging. 2011 Mar;32(3):555.e1-8. Abstract

40. Deutsch MB, Mendez MF, Teng E. Interactions between traumatic brain injury and frontotemporal degeneration. Dement Geriatr Cogn Disord. 2015;39(3-4):143-53.Full text  Abstract

41. Wang HK, Lee YC, Huang CY, et al. Traumatic brain injury causes frontotemporal dementia and TDP-43 proteolysis. Neuroscience. 2015 Aug 6;300:94-103. Abstract

42. Huang CH, Lin CW, Lee YC, et al. Is traumatic brain injury a risk factor for neurodegeneration? A meta-analysis of population-based studies. BMC Neurol. 2018 Nov 5;18(1):184.Full text  Abstract

43. Josephs KA, Hodges JR, Snowden JS, et al. Neuropathological background of phenotypical variability in frontotemporal dementia. Acta Neuropathol. 2011 Aug;122(2):137-53.Full text  Abstract

44. Mackenzie IR, Neumann M, Baborie A, et al. A harmonized classification system for FTLD-TDP pathology. Acta Neuropathol. 2011 Jul;122(1):111-3.Full text  Abstract

45. Neumann M, Mackenzie IRA. Review: Neuropathology of non-tau frontotemporal lobar degeneration. Neuropathol Appl Neurobiol. 2019 Feb;45(1):19-40. Abstract

46. Mackenzie IR, Neumann M. Molecular neuropathology of frontotemporal dementia: insights into disease mechanisms from postmortem studies. J Neurochem. 2016 Aug;138(suppl 1):54-70.Full text  Abstract

47. Lee G, Leugers CJ. Tau and tauopathies. Prog Mol Biol Transl Sci. 2012;107:263-93.Full text  Abstract

48. Rademakers R, Neumann M, Mackenzie IR. Advances in understanding the molecular basis of frontotemporal dementia. Nat Rev Neurol. 2012 Aug;8(8):423-34.Full text  Abstract

49. Paloneva J, Kestilä M, Wu J, et al. Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts. Nat Genet. 2000 Jul;25(3):357-61. Abstract

50. Paloneva J, Manninen T, Christman G, et al. Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype. Am J Hum Genet. 2002 Sep;71(3):656-62.Full text  Abstract

51. Kennedy DP, Adolphs R. The social brain in psychiatric and neurological disorders. Trends Cogn Sci. 2012 Nov;16(11):559-72.Full text  Abstract

52. Boeve BF. Links between frontotemporal lobar degeneration, corticobasal degeneration, progressive supranuclear palsy, and amyotrophic lateral sclerosis. Alzheimer Dis Assoc Disord. 2007 Oct-Dec;21(4):S31-8. Abstract

53. LoBue C, Wilmoth K, Cullum CM, et al. Traumatic brain injury history is associated with earlier age of onset of frontotemporal dementia. J Neurol Neurosurg Psychiatry. 2016 Aug;87(8):817-20.Full text  Abstract

54. Livingston G, Huntley J, Sommerlad A, et al. Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. Lancet. 2020 Aug 8;396(10248):413-46.Full text  Abstract

55. Ngandu T, Lehtisalo J, Solomon A, et al. A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial. Lancet. 2015 Jun 6;385(9984):2255-63. Abstract

56. Vellas B, Carrie I, Gillette-Guyonnet S, et al. MAPT study: a multidomain approach for preventing Alzheimer's disease: design and baseline data. J Prev Alzheimers Dis. 2014 Jun;1(1):13-22.Full text  Abstract

57. Moll van Charante EP, Richard E, Eurelings LS, et al. Effectiveness of a 6-year multidomain vascular care intervention to prevent dementia (preDIVA): a cluster-randomised controlled trial. Lancet. 2016 Aug 20;388(10046):797-805. Abstract

58. Olney NT, Spina S, Miller BL. Frontotemporal dementia. Neurol Clin. 2017 May;35(2):339-74.Full text  Abstract

59. Johnen A, Bertoux M. Psychological and cognitive markers of behavioral variant frontotemporal dementia-a clinical neuropsychologist's view on diagnostic criteria and beyond. Front Neurol. 2019 Jun 7;10:594.Full text  Abstract

60. NHMRC Partnership Centre for Dealing with Cognitive and Related Functional Decline in Older People. Clinical practice guidelines and principles of care for people with dementia. Feb 2016 [internet publication].Full text

61. Goldman JS, Rademakers R, Huey ED, et al. An algorithm for genetic testing of frontotemporal lobar degeneration. Neurology. 2011 Feb 1;76(5):475-83.Full text  Abstract

62. Davis DH, Creavin ST, Yip JL, et al. Montreal Cognitive Assessment for the detection of dementia. Cochrane Database Syst Rev. 2021 Jul 13;(7):CD010775.Full text  Abstract

63. Dubois B, Slachevsky A, Litvan I, et al. The FAB: a frontal assessment battery at bedside. Neurology. 2000 Dec 12;55(11):1621-6. Abstract

64. Royall DR, Mahurin RK, Gray KF. Bedside assessment of executive cognitive impairment: the executive interview. J Am Geriatr Soc. 1992 Dec;40(12):1221-6. Abstract

65. Larson EB, Heinemann AW. Rasch analysis of the Executive Interview (The EXIT-25) and introduction of an abridged version (The Quick EXIT). Arch Phys Med Rehabil. 2010 Mar;91(3):389-94.Full text  Abstract

66. Kumfor F, Piguet O. Disturbance of emotional processing in frontotemporal dementia: a synthesis of cognitive and neuroimaging findings. Neuropsychol Rev. 2012 Sep;22(3):280-97. Abstract

67. Mathias JL, Morphett K. Neurobehavioral differences between Alzheimer's disease and frontotemporal dementia: a meta-analysis. J Clin Exp Neuropsychol. 2010 Aug;32(7):682-98. Abstract

68. Mioshi E, Hsieh S, Savage S, et al. Clinical staging and disease progression in frontotemporal dementia. Neurology. 2010 May 18;74(20):1591-7. Abstract

69. Landqvist Waldö M, Frizell Santillo A, Passant U, et al. Cerebrospinal fluid neurofilament light chain protein levels in subtypes of frontotemporal dementia. BMC Neurol. 2013 May 29;13:54.Full text  Abstract

70. Meeter LH, Dopper EG, Jiskoot LC, et al. Neurofilament light chain: a biomarker for genetic frontotemporal dementia. Ann Clin Transl Neurol. 2016 Aug;3(8):623-36.Full text  Abstract

71. Chaudhry A, Houlden H, Rizig M. Novel fluid biomarkers to differentiate frontotemporal dementia and dementia with Lewy bodies from Alzheimer's disease: a systematic review. J Neurol Sci. 2020 Aug 15;415:116886. Abstract

72. van der Ende EL, Xiao M, Xu D, et al. Neuronal pentraxin 2: a synapse-derived CSF biomarker in genetic frontotemporal dementia. J Neurol Neurosurg Psychiatry. 2020 Jun;91(6):612-21.Full text  Abstract

73. Whitwell JL. FTD spectrum: neuroimaging across the FTD spectrum. Prog Mol Biol Transl Sci. 2019;165:187-223.Full text  Abstract

74. Agosta F, Galantucci S, Magnani G, et al. MRI signatures of the frontotemporal lobar degeneration continuum. Hum Brain Mapp. 2015 Jul;36(7):2602-14. Abstract

75. Quigley HC. PET imaging of brain amyloid in dementia: a review. Int J Geriatr Psychiatry. 2011 Oct;26(10):991-9. Abstract

76. American College of Radiology. ACR-ACNM-ASNR-SNMMI practice parameter for brain PET-CT imaging in dementia. 2020 [internet publication].Full text

77. Bruun M, Koikkalainen J, Rhodius-Meester HFM, et al. Detecting frontotemporal dementia syndromes using MRI biomarkers. Neuroimage Clin. 2019;22:101711.Full text  Abstract

78. Perry A, Wen W, Lord A, et al. The organisation of the elderly connectome. Neuroimage. 2015 Jul 1;114:414-26. Abstract

79. Lam BY, Halliday GM, Irish M, et al. Longitudinal white matter changes in frontotemporal dementia subtypes. Hum Brain Mapp. 2014 Jul;35(7):3547-57. Abstract

80. Goldman J. New approaches to genetic counseling and testing for Alzheimer’s disease and frontotemporal degeneration. Curr Neurol Neurosci Rep. 2012 Oct;12(5):502-10.Full text  Abstract

81. Cairns NJ, Bigio EH, Mackenzie IR, et al. Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration. Acta Neuropathol. 2007 Jul;114(1):5-22.Full text  Abstract

82. McKhann GM, Albert MS, Grossman M, et al. Clinical and pathological diagnosis of frontotemporal dementia: report of the Work Group on Frontotemporal Dementia and Pick's Disease. Arch Neurol. 2001 Nov;58(11):1803-9. Abstract

83. Snowden JS, Neary D, Mann DM. Frontotemporal dementia. Br J Psychiatry. 2002 Feb;180:140-3. Abstract

84. Ikeda M, Brown J, Holland AJ, et al. Changes in appetite, food preference, and eating habits in frontotemporal dementia and Alzheimer's disease. J Neurol Neurosurg Psychiatry. 2002 Oct;73(4):371-6.Full text  Abstract

85. Moheb N, Charuworn K, Ashla MM, et al. Repetitive behaviors in frontotemporal dementia: compulsions or impulsions? J Neuropsychiatry Clin Neurosci. 2019 Spring;31(2):132-6.Full text  Abstract

86. Mendez MF, Lauterbach EC, Sampson SM, et al. An evidence-based review of the psychopathology of frontotemporal dementia: a report of the ANPA Committee on Research. J Neuropsychiatry Clin Neurosci. 2008 Spring;20(2):130-49. Abstract

87. Mosconi L, Tsui WH, Herholz K, et al. Multicenter standardized 18F-FDG PET diagnosis of mild cognitive impairment, Alzheimer's disease, and other dementias. J Nucl Med. 2008 Mar;49(3):390-8.Full text  Abstract

88. Goldman JS, Farmer JM, Van Deerlin VM, et al. Frontotemporal dementia: genetics and genetic counseling dilemmas. Neurologist. 2004 Sep;10(5):227-34. Abstract

89. Young JJ, Lavakumar M, Tampi D, et al. Frontotemporal dementia: latest evidence and clinical implications. Ther Adv Psychopharmacol. 2018 Jan;8(1):33-48.Full text  Abstract

90. Khanassov V, Vedel I. Family physician-case manager collaboration and needs of patients with dementia and their caregivers: a systematic mixed studies review. Ann Fam Med. 2016 Mar;14(2):166-77.Full text  Abstract

91. Soril LJ, Leggett LE, Lorenzetti DL, et al. Effective use of the built environment to manage behavioural and psychological symptoms of dementia: a systematic review. PLoS One. 2014 Dec 17;9(12):e115425.Full text  Abstract

92. Mulkey MA, Everhart DE, Hardin SR. Fronto-temporal dementia: a case study and strategies and support for caregivers. Br J Community Nurs. 2019 Nov 2;24(11):544-9. Abstract

93. Machiels M, Metzelthin SF, Hamers JP, et al. Interventions to improve communication between people with dementia and nursing staff during daily nursing care: a systematic review. Int J Nurs Stud. 2017 Jan;66:37-46. Abstract

94. Bott NT, Radke A, Stephens ML, et al. Frontotemporal dementia: diagnosis, deficits and management. Neurodegener Dis Manag. 2014;4(6):439-54. Abstract

95. Abraha I, Rimland JM, Trotta FM, et al. Systematic review of systematic reviews of non-pharmacological interventions to treat behavioural disturbances in older patients with dementia. The SENATOR-OnTop series. BMJ Open. 2017 Mar 16;7(3):e012759.Full text  Abstract

96. Brodaty H, Arasaratnam C. Meta-analysis of nonpharmacological interventions for neuropsychiatric symptoms of dementia. Am J Psychiatry. 2012 Sep;169(9):946-53.Full text  Abstract

97. Dyer SM, Harrison SL, Laver K, et al. An overview of systematic reviews of pharmacological and non-pharmacological interventions for the treatment of behavioral and psychological symptoms of dementia. Int Psychogeriatr. 2018 Mar;30(3):295-309.Full text  Abstract

98. Carrion C, Folkvord F, Anastasiadou D, et al. Cognitive therapy for dementia patients: a systematic review. Dement Geriatr Cogn Disord. 2018;46(1-2):1-26.Full text  Abstract

99. Bahar-Fuchs A, Martyr A, Goh AM, et al. Cognitive training for people with mild to moderate dementia. Cochrane Database Syst Rev. 2019 Mar 25;(3):CD013069.Full text  Abstract

100. van der Steen JT, Smaling HJ, van der Wouden JC, et al. Music-based therapeutic interventions for people with dementia. Cochrane Database Syst Rev. 2018 Jul 23;(7):CD003477.Full text  Abstract

101. Langhammer B, Sagbakken M, Kvaal K, et al. Music therapy and physical activity to ease anxiety, restlessness, irritability, and aggression in individuals with dementia with signs of frontotemporal lobe degeneration. J Psychosoc Nurs Ment Health Serv. 2019 May 1;57(5):29-37. Abstract

102. Watt JA, Goodarzi Z, Veroniki AA, et al. Comparative efficacy of interventions for aggressive and agitated behaviors in dementia: a systematic review and network meta-analysis. Ann Intern Med. 2019 Nov 5;171(9):633-42. Abstract

103. McCarter SJ, St Louis EK, Boeve BF. Sleep disturbances in frontotemporal dementia. Curr Neurol Neurosci Rep. 2016 Sep;16(9):85. Abstract

104. Buoli M, Serati M, Caldiroli A, et al. Pharmacological management of psychiatric symptoms in frontotemporal dementia: a systematic review. J Geriatr Psychiatry Neurol. 2017 May;30(3):162-9. Abstract

105. Trieu C, Gossink F, Stek ML, et al. Effectiveness of pharmacological interventions for symptoms of behavioral variant frontotemporal dementia: a systematic review. Cogn Behav Neurol. 2020 Mar;33(1):1-15. Abstract

106. Reus VI, Fochtmann LJ, Eyler AE, et al. The American Psychiatric Association practice guideline on the use of antipsychotics to treat agitation or psychosis in patients with dementia. Am J Psychiatry. 2016 May 1;173(5):543-6.Full text  Abstract

107. Magierski R, Sobow T, Schwertner E, et al. Pharmacotherapy of behavioral and psychological symptoms of dementia: state of the art and future progress. Front Pharmacol. 2020 Jul 31;11:1168.Full text  Abstract

108. Ralph SJ, Espinet AJ. Increased all-cause mortality by antipsychotic drugs: updated review and meta-analysis in dementia and general mental health care. J Alzheimers Dis Rep. 2018 Feb 2;2(1):1-26.Full text  Abstract

109. Yunusa I, Alsumali A, Garba AE, et al. Assessment of reported comparative effectiveness and safety of atypical antipsychotics in the treatment of behavioral and psychological symptoms of dementia: a network meta-analysis. JAMA Netw Open. 2019 Mar 1;2(3):e190828.Full text  Abstract

110. Boxer AL, Boeve BF. Frontotemporal dementia treatment: current symptomatic therapies and implications of recent genetic, biochemical, and neuroimaging studies. Alzheimer Dis Assoc Disord. 2007 Oct-Dec;21(4):S79-87. Abstract

111. McCleery J, Sharpley AL. Pharmacotherapies for sleep disturbances in dementia. Cochrane Database Syst Rev. 2020 Nov 15;(11):CD009178.Full text  Abstract

112. Drayton SJ, Davies K, Steinberg M, et al. Amantadine for executive dysfunction syndrome in patients with dementia. Psychosomatics. 2004 May-Jun;45(3):205-9. Abstract

113. Boxer AL, Knopman DS, Kaufer DI, et al. Memantine in patients with frontotemporal lobar degeneration: a multicentre, randomised, double-blind, placebo-controlled trial. Lancet Neurol. 2013 Feb;12(2):149-56.Full text  Abstract

114. McShane R, Westby MJ, Roberts E, et al. Memantine for dementia. Cochrane Database Syst Rev. 2019 Mar 20;3(3):CD003154.Full text  Abstract

115. Galvez-Andres A, Blasco-Fontecilla H, Gonzalez-Parra S, et al. Secondary bipolar disorder and Diogenes syndrome in frontotemporal dementia: behavioral improvement with quetiapine and sodium valproate. J Clin Psychopharmacol. 2007 Dec;27(6):722-3. Abstract

116. Chow TW, Mendez MF. Goals in symptomatic pharmacologic management of frontotemporal lobar degeneration. Am J Alzheimers Dis Other Demen. 2002 Sep-Oct;17(5):267-72.Full text  Abstract

117. European Medicines Agency. New measures to avoid valproate exposure in pregnancy endorsed. Mar 2018 [internet publication].Full text

118. Tsai RM, Boxer AL. Treatment of frontotemporal dementia. Curr Treat Options Neurol. 2014 Nov;16(11):319.Full text  Abstract

119. El-Sohl AA, Niederman MS, Drinka P. Nursing home-acquired pneumonia: a review of risk factors and therapeutic approaches. Curr Med Res Opin. 2010 Dec;26(12):2707-14. Abstract

120. Taylor LP, Besbris JM, Graf WD, et al. Clinical guidance in neuropalliative care: an AAN position statement. Neurology. 2022 Mar 8;98(10):409-16.Full text  Abstract

121. Chiong W, Tsou AY, Simmons Z, et al. Ethical considerations in dementia diagnosis and care: AAN position statement. Neurology. 2021 Jul 13;97(2):80-9.Full text  Abstract

122. Davies N, Barrado-Martín Y, Vickerstaff V, et al. Enteral tube feeding for people with severe dementia. Cochrane Database Syst Rev. 2021 Aug 13;(8):CD013503.Full text  Abstract

123. Boxer AL, Gold M, Huey E, et al. Frontotemporal degeneration, the next therapeutic frontier: molecules and animal models for frontotemporal drug development. Alzheimers Dement. 2013 Mar;9(2):176-88.Full text  Abstract

124. Seripa D, Solfrizzi V, Imbimbo BP, et al. Tau-directed approaches for the treatment of Alzheimer's disease: focus on leuco-methylthioninium. Expert Rev Neurother. 2016;16(3):259-77. Abstract

125. Min SW, Chen X, Tracy TE, et al. Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits. Nat Med. 2015 Oct;21(10):1154-62.Full text  Abstract

126. Liu W, Zhao L, Blackman B, et al. Vectored intracerebral immunization with the anti-tau monoclonal antibody PHF1 markedly reduces tau pathology in mutant tau transgenic mice. J Neurosci. 2016 Dec 7;36(49):12425-35.Full text  Abstract

127. Gozes I, Ivashko-Pachima Y. ADNP: in search for molecular mechanisms and innovative therapeutic strategies for frontotemporal degeneration. Front Aging Neurosci. 2015 Oct 29;7:205.Full text  Abstract

128. Alberici A, Archetti S, Pilotto A, et al. Results from a pilot study on amiodarone administration in monogenic frontotemporal dementia with granulin mutation. Neurol Sci. 2014 Aug;35(8):1215-9. Abstract

129. Lagier-Tourenne C, Baughn M, Rigo F, et al. Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):E4530-9.Full text  Abstract

130. Supasitthumrong T, Bolea-Alamanac BM, Asmer S, et al. Gabapentin and pregabalin to treat aggressivity in dementia: a systematic review and illustrative case report. Br J Clin Pharmacol. 2019 Apr;85(4):690-703.Full text  Abstract

131. Xie SX, Forman MS, Farmer J, et al. Factors associated with survival probability in autopsy-proven frontotemporal lobar degeneration. J Neurol Neurosurg Psychiatry. 2008 Feb;79(2):126-9. Abstract

132. Pasquier F, Richard F, Lebert F. Natural history of frontotemporal dementia: comparison with Alzheimer's disease. Dement Geriatr Cogn Disord. 2004;17(4):253-7. Abstract

133. Borroni B, Grassi M, Agosti C, et al. Survival in frontotemporal lobar degeneration and related disorders: latent class predictors and brain functional correlates. Rejuvenation Res. 2009 Feb;12(1):33-44. Abstract

134. Kang SJ, Cha KR, Seo SW, et al. Survival in frontotemporal lobar degeneration in a Korean population. Alzheimer Dis Assoc Disord. 2010 Oct-Dec;24(4):339-42. Abstract

135. Chiu WZ, Kaat LD, Seelaar H, et al. Survival in progressive supranuclear palsy and frontotemporal dementia. J Neurol Neurosurg Psychiatry. 2010 Apr;81(4):441-5. Abstract

136. Nunnemann S, Last D, Schuster T, et al. Survival in a German population with frontotemporal lobar degeneration. Neuroepidemiology. 2011;37(3-4):160-5. Abstract

137. Rascovsky K, Salmon DP, Lipton AM, et al. Rate of progression differs in frontotemporal dementia and Alzheimer disease. Neurology. 2005 Aug 9;65(3):397-403. Abstract

138. Arena JE, Weigand SD, Whitwell JL, et al. Progressive supranuclear palsy: progression and survival. J Neurol. 2016 Feb;263(2):380-9. Abstract

139. Nath U, Ben-Shlomo Y, Thomson RG, et al. Clinical features and natural history of progressive supranuclear palsy: a clinical cohort study. Neurology. 2003 Mar 25;60(6):910-6. Abstract

140. Riedijk SR, de Vugt ME, Duivenvoorden HJ, et al. Caregiver burden, health-related quality of life and coping in dementia caregivers: a comparison of frontotemporal dementia and Alzheimer's disease. Dement Geriatr Cogn Disord. 2006;22(5-6):405-12. Abstract

141. Toepper M, Falkenstein M. Driving fitness in different forms of dementia: an update. J Am Geriatr Soc. 2019 Oct;67(10):2186-92. Abstract

142. Iverson DJ, Gronseth GS, Reger MA, et al. Practice parameter update: evaluation and management of driving risk in dementia: report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2010 Apr 20;74(16):1316-24.Full text  Abstract

143. Driving and Dementia Working Group. Driving with dementia or mild cognitive impairment: consensus guidelines for clinicians. 2018 [internet publication].Full text

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