Резюме
Определение
Анамнез и осмотр
Ключевые диагностические факторы
- family history of vision loss
- history of retinitis pigmentosa
- congenital stationary night blindness
- past medical history of vitamin A deficiency or malignancy
Другие диагностические факторы
- decreased visual acuity in dim light
- variable pupillary responses (depending on underlying cause)
- retinal vascular attenuation
- visual field loss
- peripheral chorioretinal degeneration
- history of drugs that interfere with vitamin A metabolism
Факторы риска
- retinitis pigmentosa
- congenital stationary night blindness
- vitamin A deficiency
- cancer-associated retinopathy
- melanoma-associated retinopathy
- gyrate atrophy
- choroideremia
Диагностические исследования
Исследования, которые показаны в первую очередь
- electroretinography (ERG)
- slit-biomicroscopy and indirect ophthalmoscopy
Исследования, проведение которых нужно рассмотреть
- serum vitamin A level
- next-generation-sequencing
Алгоритм лечения
genetic night blindness
acquired night blindness
Составители
Авторы
Jonathan Smith, FRCOphth, MRCP
Consultant Ophthalmologist
Sunderland Eye Infirmary
Sunderland
UK
Раскрытие информации
JS has received sponsorship from Novartis, Bayer, and DORC for meeting travel and accommodation. JS was awarded a research grant in 2017 by the British Vitreoretinal Society.
Muhammad Raza Cheema, MRCGP, MRes, FRCOphth, FEBO
Specialist Registrar
Ophthalmology
Sunderland Eye Infirmary
Sunderland
UK
Раскрытие информации
MRC declares that he has no competing interests.
Wendy Adams, MRCP, FRCOphth
Consultant Ophthalmologist
Sunderland Eye Infirmary
Sunderland
UK
Раскрытие информации
WA declares that she has no competing interests.
Выражение благодарностей
Dr Jonathan Smith, Dr Wendy Adams, and Dr Muhammad Raza Cheema would like to gratefully acknowledge the assistance of Ms Karen Bradshaw. KB declares that she has no competing interests.
Рецензенты
Makoto Nakamura, MD
Associate Professor
Department of Ophthalmology
Nagoya University Graduate School of Medicine
Nagoya
Japan
Раскрытие информации
MN declares that he has no competing interests.
Eric Amesbury, MD
Klara Spinks Fleming Fellow
Jules Stein Eye Institute
UCLA
Los Angeles
CA
Declarações
EA declares that he has no competing interests.
Creig S. Hoyt, MD
Emeritus Professor and Chairman
Department of Ophthalmology
University of California
San Francisco
CA
Declarações
CSH declares that he has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
Referências
Principais artigos
Hartong DT, Berson EL, Dryja TP. Retinitis pigmentosa. Lancet. 2006 Nov 18;368(9549):1795-809. Resumo
Petzold A, Plant GT. Clinical disorders affecting mesopic vision. Ophthalmic Physiol Opt. 2006 May;26(3):326-41. Resumo
Goodwin P. Hereditary retinal disease. Curr Opin Ophthalmol. 2008 May;19(3):255-62. Resumo
Law WC, Rando RR. The molecular basis of retinoic acid induced night blindness. Biochem Biophys Res Commun. 1989 Jun 15;161(2):825-9. Resumo
Artigos de referência
Uma lista completa das fontes referenciadas neste tópico está disponível para os usuários com acesso total ao BMJ Best Practice.
Diagnósticos diferenciais
- Myopia
- Glaucoma
- Optic neuropathy
Mais Diagnósticos diferenciaisDiretrizes
- Vision rehabilitation preferred practice pattern
- Standard for full-field clinical electroretinography
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