In the US, the prevalence of membranous nephropathy is close to 2000 patients per year. In contrast to other primary glomerular diseases, the incidence of MN has remained constant since the 1980s. It is one of the most common causes of nephrotic syndrome globally, just behind focal segmental glomerular sclerosis, which is the most common aetiology. This disease affects patients of all ages and races but is more common in men, and is most commonly diagnosed in middle age. Incidence peaks in the fourth to fifth decades of life. MN is rare in the paediatric population but is serious when it occurs.
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