Epidemiology

Approximately 80 to 85 children each year are diagnosed with Wilms' tumours in the UK.[21] In the US, approximately 500 children and adolescents <20 years of age are diagnosed each year.[3][4] The incidence has not changed globally during a 21-year period.[22][23][24][25][26][27][28][29] The incidence was thought to be slightly higher in females and black children when compared to males and white children;[22] more recent data, however, show equal incidence in both sexes and among black and white children.[22][23][24][27][30] Incidence in Asian people is about half that of black and white people.[3][24][31] White children have an increased incidence of loss of IGF2 imprinting in precursor renal lesions and Wilms' tumours compared to children of Asian descent.[32][33][34]

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