Approximately 80 to 85 children each year are diagnosed with Wilms' tumours in the UK. In the US, approximately 500 children and adolescents <20 years of age are diagnosed each year. The incidence has not changed globally during a 21-year period. The incidence was thought to be slightly higher in females and black children when compared to males and white children; more recent data, however, show equal incidence in both sexes and among black and white children. Incidence in Asian people is about half that of black and white people. White children have an increased incidence of loss of IGF2 imprinting in precursor renal lesions and Wilms' tumours compared to children of Asian descent.
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