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Strongyloides infection

Последний просмотренный: 19 Aug 2025
Last updated: 02 Aug 2023

Резюме

Определение

Анамнез и осмотр

Ключевые диагностические факторы

  • history of soil exposure in an endemic area
  • infection with other parasites
Полная информация

Другие диагностические факторы

  • abdominal pain
  • altered bowel habit
  • weight loss
  • fever (hyperinfection)
  • signs of sepsis (hyperinfection)
  • chronic cough
  • wheezing
  • pruritus or dermatitis
  • larva currens
  • urticaria
  • cutaneous larva migrans
  • apparent drug reaction rash (hyperinfection)
  • other skin complaints
  • symptoms and signs of inflammatory bowel disease
Полная информация

Факторы риска

  • soil exposure in or migrants from an endemic area of the world
  • international travelers
  • corticosteroids (risk of hyperinfection)
  • human T-cell lymphotropic virus type-1 (HTLV-1) infection (risk of hyperinfection)
  • impaired immunity
  • solid-organ transplant recipient
Полная информация

Диагностические исследования

Исследования, которые показаны в первую очередь

  • stool ova and parasites (O&P) exam
  • CBC with differential
  • therapeutic trial with ivermectin (in specific situations)
Полная информация

Исследования, проведение которых нужно рассмотреть

  • sputum O&P exam
  • clinical sample (nonstool or sputum) O&P exam
  • strongyloides IgG serology
  • tissue biopsy
Полная информация

Неотложные исследования

  • polymerase chain reaction (PCR)

Алгоритм лечения

Начальные

immigrant from endemic area

Острый

able to tolerate oral therapy: not critically ill (nonpregnant)

unable to tolerate oral therapy or critically ill (nonpregnant)

pregnant

ПРОДОЛЖЕНИЕ

poor clinical response or initial treatment not completed

Составители

Авторы

David R. Boulware, MD, MPH, CTropMed
David R. Boulware

Professor of Medicine

Department of Medicine

University of Minnesota

Minneapolis

MN

Раскрытие информации

DRB is an author of a number of references cited in this topic.

Рецензенты

Elizabeth Barnett, MD

Professor

Department of Pediatrics

Boston Medical Center

Boston University

Boston

MA

Раскрытие информации

EB declares that she is on a speaker's bureau for Merck. She is an author of a reference cited in this topic.

Linda Nield, MD, FAAP

Professor of Pediatrics

West Virginia University School of Medicine

Morgantown

WV

Раскрытие информации

LN is an author of a reference cited in this topic.

Geoff Gill, MA, MSc, MD, FRCP, DTMH

Professor of International Medicine and Honorary Consultant Physician

Liverpool School of Tropical Medicine

Liverpool

UK

Раскрытие информации

GG declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

Список литературы

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Основные статьи

World Gastroenterology Organisation. WGO practice guideline: management of strongyloidiasis. February 2018 [internet publication].Полный текст

Loutfy MR, Wilson M, Keystone JS, et al. Serology and eosinophil count in the diagnosis and management of strongyloidiasis in a non-endemic area. Am J Trop Med Hyg. 2002 Jun;66(6):749-52. Аннотация

Henriquez-Camacho C, Gotuzzo E, Echevarria J, et al. Ivermectin versus albendazole or thiabendazole for Strongyloides stercoralis infection. Cochrane Database Syst Rev. 2016 Jan 18;(1):CD007745.Полный текст  Аннотация

Статьи, указанные как источники

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

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