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Contact dermatitis

最后审阅: 9 Dec 2025
最后更新: 20 Jun 2023

小结

定义

病史和体格检查

关键诊断因素

  • occupational history of exposure
  • history of atopic dermatitis
  • previous episodes of similar dermatitis
  • acute onset
  • affecting hands and face
  • affecting sun-exposed skin
  • sparing of non-exposed areas of skin
  • pruritus
  • burning
  • erythema
  • vesicles and bullae
  • urticaria
  • lichenoid lesions
  • corrosion or ulceration
  • pustules and acneiform lesions
完整详情

其他诊断因素

  • scaling
  • lichenification
  • social history of exposure
  • persistence of symptoms
  • crusting
  • erythema multiforme
  • cellulitic lesions
  • leukoderma
  • hypopigmentation/depigmentation
  • hyperpigmentation
  • purpura
  • miliaria
  • alopecia
  • granulomatous lesions
完整详情

危险因素

  • occupation with frequent exposure to water or caustic material
  • atopic dermatitis
完整详情

诊断性检查

首要检查

  • patch testing
完整详情

需考虑的检查

  • repeated open application test (ROAT) or provocative use test (PUT)
  • skin biopsy
完整详情

治疗流程

急症处理

irritant contact dermatitis

allergic contact dermatitis (ACD)

持续性治疗

contact dermatitis

撰稿人

作者

JiaDe Yu, MD, FAAD

Assistant Professor of Adult and Pediatric Dermatology

Director of Contact and Occupational Dermatology

Department of Dermatology

Massachusetts General Hospital

Harvard Medical School

Boston

MA

利益声明

JY was on the board for the American Contact Dermatitis Society from 2019-2022 (term ended and unpaid). JY has received a career development grant from the Dermatology Foundation and research grants from the Pediatric Dermatology Research Alliance and the American Contact Dermatitis Society. JY has received honorarium from the National Eczema Association for consultant work as part of its SEAL of approval project, and is on the editorial board for the Pediatric Dermatology journal and the Dermatitis journal.

鸣谢

Dr JiaDe Yu would like to gratefully acknowledge Dr Gerard Guillet, Dr David M. Ozog, and Dr Snehal Desai, previous contributors to this topic.

利益声明

GG, DMO, and SD declare that they have no competing interests.

同行评议者

Christen Mowad, MD

Assistant Professor

Department of Dermatology

Geisinger Medical Center

Danville

PA

利益声明

CM declares that he has no competing interests.

John English, MBBS, FRCP

Consultant Dermatologist

Department of Dermatology

Queen's Medical Centre

Nottingham University Hospitals

Nottingham

UK

利益声明

JE declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

参考文献

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

关键文献

Johnston GA, Exton LS, Mohd Mustapa MF, et al. British Association of Dermatologists' guidelines for the management of contact dermatitis 2017. Br J Dermatol. 2017 Feb;176(2):317-29.全文  摘要

Johansen JD, Aalto-Korte K, Agner T, et al. European Society of Contact Dermatitis guideline for diagnostic patch testing: recommendations on best practice. Contact Dermatitis. 2015 Oct;73(4):195-221.全文  摘要

Fonacier L, Bernstein DI, Pacheco K, et al; American Academy of Allergy, Asthma & Immunology; American College of Allergy, Asthma & Immunology; Joint Council of Allergy, Asthma & Immunology. Contact dermatitis: a practice parameter - update 2015. J Allergy Clin Immunol Pract. 2015 May-Jun;3(3 Suppl):S1-39.全文  摘要

参考文献

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
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  • 指南

    • Pediatric allergic contact dermatitis. Part I: Clinical features and common contact allergens in children
    • ​Pediatric allergic contact dermatitis. Part 2: Patch testing series, procedure, and unique scenarios
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