Approach

Diagnosis of MEN syndromes involves careful screening of patients with endocrine tumours. Diagnostic suspicion is raised if numerous symptoms are present. Diagnosis of MEN1 is based on patients having 2 or more MEN1-associated tumours, or 1 associated tumour and a first-degree relative with the condition, or on the basis of genetics alone with a diagnosed pathogenic mutation of MEN1.[1]

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